Defining polypharmacy in the elderly: A systematic review protocol

BMJ Open

Volumn 6, Issue 3, 2016, Pages

  Mortazavi, Seyede Salehe ^a   Shati, Mohsen ^b   Keshtkar, Abasali ^c   Malakouti, Seyed Kazem ^a   Bazargan, Mohsen ^d   Assari, Shervin ^e,f  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^e UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; CONSENSUS DEVELOPMENT; GERIATRIC CARE; HUMAN; MEDICAL EXPERT; POLYPHARMACY; REVIEW; RISK ASSESSMENT; RISK FACTOR; SYSTEMATIC REVIEW; AGING; BIBLIOGRAPHIC DATABASE; LITERATURE; METHODOLOGY;

AGED; AGING; DATABASES, BIBLIOGRAPHIC; HUMANS; POLYPHARMACY; RESEARCH DESIGN; REVIEW LITERATURE AS TOPIC;

EID: 84962304148     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2015-010989     Document Type: Review

References (30)

1. Patterson SM, Hughes CA, Kerse N, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev 2012;5:CD008165.
2. Johnell K, Klarin I. The relationship between number of drugs and potential drug-drug interactions in the elderly. Drug Saf 2007;30:911-18.
3. Prybys K, Melville K, Hanna J, et al. Polypharmacy in the elderly: clinical challenges in emergency practice: part 1 overview, etiology, and drug interactions. Emerg Med Rep 2002;23:145-53.
4. Fick D, Semla T, Beizer J, etal. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am GeriatrSoc 2012;60:616-31.
5. Fick DM, Cooper JW, Wade WE, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003;163:2716.
6. Gnjidic D, Le Couteur DG, Kouladjian L, et al. Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes. Clin Geriatr Med 2012;28:237-53.
7. Fulton MM, Allen ER. Polypharmacy in the elderly: a literature review. J Am Acad Nurse Pract 2005;17:123-32.
8. Duerden M, Avery T, Payne R. Polypharmacy and medicines optimisation: making it safe and sound. 2013. http://www.volgmed.ru/uploads/files/2014-12/35099-prilozhenie-1-3-k-informacionnomu-pismu-2.pdf
9. Friend DG. Polypharmacy; multiple-ingredient and shotgun prescriptions. N Engl J Med 1959;260:1015-18.
10. De las Cuevas C, Sanz EJ. Polypharmacy in psychiatric practice in the Canary Islands. BMC Psychiatry 2004;4:18.
11. Riker GI, Setter SM. Polypharmacy in older adults at home: what it is and what to do about it-implications for home healthcare and hospice. Home Healthc Nurse 2012;30:474-85.
12. de la Varre C. Polypharmacy in older adults: the effective design of an online information resource. University of North Carolina, 2000.
13. Williams A, Manias E, Walker R. Interventions to improve medication adherence in people with multiple chronic conditions: a systematic review. J Adv Nurs 2008;63:132-43.
14. MacLaughlin EJ, Raehl CL, Treadway AK, et al. Assessing medication adherence in the elderly: which tools to use in clinical practice? Drugs Aging 2005;22:231-55.
15. Wise J. Polypharmacy: a necessary evil. BMJ 2013;347:f7033.
16. Guthrie B, Payne K, Alderson P, etal. Adapting clinical guidelines to take account of multimorbidity. BMJ 2012;345:e6341.
17. Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother 2007;5:345-51.
18. Baker DW, Wolf MS, Feinglass J, et al. Health literacy and mortality among elderly persons. Arch Intern Med 2007;167:1503-9.
19. Burkhardt H. Polypharmacy. In: Wehling M, ed. Drug therapy for the elderly. Vienna: Springer, 2013:319-29.
20. Rollason V, Vogt N. Reduction of polypharmacy in the elderly. Drugs Aging 2003;20:817-32.
21. Salih SB, Yousuf M, Durihim H, etal. Prevalence and associated factors of polypharmacy among adult Saudi medical outpatients at a tertiary care center. J Family Community Med 2013;20:162-7.
22. Rohrer JE, Garrison G, Oberhelman SA, etal. Epidemiology of polypharmacy among family medicine patients at hospital discharge. J Prim Care Community Health 2013;4:101-5.
23. Kojima T, Akishita M, Nakamura T, et al. Polypharmacy as a risk for fall occurrence in geriatric outpatients. Geriatr Gerontol Int 2012;12:425-30.
24. Dwyer LL, Han B, Woodwell DA, etal. Polypharmacy in nursing home residents in the United States: results of the 2004 National Nursing Home Survey. Am J Geriatr Pharmacother 2010;8:63-72.
25. Lai SW, Su LT, Lin CH, et al. Polypharmacy increases the risk of Parkinson's disease in older people in Taiwan: a population-based study. Psychogeriatrics 2011;11:150-6.
26. Nguyen JK, Fouts MM, Kotabe SE, et al. Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents. Am J Geriatr Pharmacother 2006;4:36-41.
27. Aparasu RR, Mort JR. Prevalence, correlates, and associated outcomes of potentially inappropriate psychotropic use in the community-dwelling elderly. Am J Geriatr Pharmacother 2004;2:102-11.
28. Sehgal V, Bajwa SJ, Sehgal R, et al. Polypharmacy and potentially inappropriate medication use as the precipitating factor in readmissions to the hospital. J Family Med Prim Care 2013;2:194.
29. World Health organization. Ageing and health. 2015. http://www.who.int/mediacentre/factsheets/fs404/en/ (accessed 11 01 2015).
30. Bregnhøj L, Thirstrup S, Kristensen MB, etal. Combined intervention programme reduces inappropriate prescribing in elderly patients exposed to polypharmacy in primary care. Eur J Clin Pharmacol 2009;65:199-207.