Polypharmacy as a risk for fall occurrence in geriatric outpatients

Geriatrics and Gerontology International

Volumn 12, Issue 3, 2012, Pages 425-430

  Kojima, Taro ^a   Akishita, Masahiro ^a   Nakamura, Tetsuro ^b   Nomura, Kazushi ^a   Ogawa, Sumito ^a   Iijima, Katsuya ^a   Eto, Masato ^a   Ouchi, Yasuyoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Research Institute of Aging Science   (Japan)

Author keywords

Bone musculo skeletal; Elderly; Falls; Geriatric medicine; Internal medicine; Polypharmacy

Indexed keywords

AGED; ANAMNESIS; ARTICLE; COMORBIDITY; FALL RISK; FEMALE; FOLLOW UP; GERIATRIC PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; PHYSICAL EXAMINATION; PHYSICIAN; POLYPHARMACY; PRIORITY JOURNAL; SELF REPORT;

ACCIDENTAL FALLS; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; LOGISTIC MODELS; MALE; OUTPATIENTS; POLYPHARMACY; RISK FACTORS;

EID: 84862641416     PISSN: 14441586     EISSN: 14470594     Source Type: Journal    
DOI: 10.1111/j.1447-0594.2011.00783.x     Document Type: Article

References (22)

1. Stel VS, Pluijm SM, Deeg DJ, Smit JH, Bouter LM, Lips P. A classification tree for predicting recurrent falling in community- dwelling older persons. J Am Geriatr Soc 2003; 51: 1356-1364.
2. Kojima S, Furuna T, Ikeda N, Nakamura M, Sawada Y. Falls among community-dwelling elderly people of Hokkaido, Japan. Geriatr Gerontol Int 2008; 8: 272-277.
3. Okochi J, Toba T, Takahashi T etal. Simple screening test for risk of falls in the elderly. Geriatr Gerontol Int 2006; 6: 223-227.
4. Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systematic review and meta-analysis: II. Cardiac and analgesic drugs. J Am Geriatr Soc 1999; 47: 40-50.
5. Berlie HD, Garwood CL. Diabetes medications related to an increased risk of falls and fall-related morbidity in the elderly. Ann Pharmacother 2010; 44: 712-717.
6. Araki A, Ito H. Diabetes mellitus and geriatric syndromes. Geriatr Gerontol Int 2009; 9: 105-114.
7. Kojima T, Akishita M, Nakamura T etal. Association of polypharmacy with fall risk among geriatric outpatients. Geriatr Gerontol Int 2011; 11: 438-444.
8. Toba K, Okochi J, Takahashi T etal. Development of a portable fall risk index for elderly people living in the community. Nippon Ronen Igakkai Zasshi 2005; 42: 346-352. (In Japanese.)
9. Kron M, Loy S, Sturm E etal. Risk indicators for falls in institutionalized frail elderly. Am J Epidemiol 2003; 158: 645-653.
10. van Doorn C, Gruber-Baldini AL, Zimmerman S etal. Dementia as a risk factor for falls and fall injuries among nursing home residents. J Am Geriatr Soc 2003; 51: 1213-1218.
11. Halfon P, Eggli Y, Van Melle G, Vagnair A. Risk of falls for hospitalized patients: a predictive model based on routinely available data. J Clin Epidemiol 2001; 54: 1258-1266.
12. Tanaka M, Suemaru K, Ikegawa Y etal. Relationship between the risk of falling and drugs in an academic hospital. Yakugaku Zasshi 2008; 128: 1355-1361.
13. Ensrud KE, Blackwell TL, Redline S etal. Sleep disturbances and frailty status in older community-dwelling men. J Am Geriatr Soc 2009; 57: 2085-2093.
14. Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systematic review and meta-analysis: I. Psychotropic drugs. J Am Geriatr Soc 1999; 47: 30-39.
15. Woolcott JC, Richardson KJ, Wiens MO etal. Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med 2009; 169: 1952-1960.
16. Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med 1988; 319: 1701-1707.
17. Kelly KD, Pickett W, Yiannakoulias N etal. Medication use and falls in community-dwelling older persons. Age Ageing 2003; 32: 503-509.
18. Thapa PB, Gideon P, Cost TW, Milam AB, Ray WA. Antidepressants and the risk of falls among nursing home residents. N Engl J Med 1998; 339: 875-882.
19. Bloem BR, Steijns JA, Smits-Engelsman BC. An update on falls. Curr Opin Neurol 2003; 16: 15-26.
20. Arai H, Akishita M, Teramoto S etal. Incidence of adverse drug reactions in geriatric units of university hospitals. Geriatr Gerontol Int 2005; 5: 293-297.
21. Iwata M, Kuzuya M, Kitagawa Y, Suzuki Y, Iguchi A. Underappreciated predictors for postdischarge mortality in acute hospitalized oldest-old patients. Gerontology 2006; 52: 92-98.
22. Baranzini F, Diurni M, Ceccon F etal. Fall-related injuries in a nursing home setting: is polypharmacy a risk factor? BMC Health Serv Res 2009; 9: 228.