Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen

Acta Neuropathologica

Volumn 132, Issue 1, 2016, Pages 43-58

  Kinzel, Silke ^a   Lehmann Horn, Klaus ^b   Torke, Sebastian ^a   Häusler, Darius ^a   Winkler, Anne ^a   Stadelmann, Christine ^a   Payne, Natalie ^c   Feldmann, Linda ^a   Saiz, Albert ^d   Reindl, Markus ^e   Lalive, Patrice H ^f   Bernard, Claude C ^c   Brück, Wolfgang ^a   Weber, Martin S ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b Technische Universität München Munich Cluster for Systems Neurology   (Germany)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF BARCELONA   (Spain)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^f GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Auto antibodies; Experimental autoimmune encephalomyelitis; Fc receptor; Multiple sclerosis; Myeloid antigen presenting cells; Opsonization

Indexed keywords

AUTOANTIGEN; CD20 ANTIBODY; FC RECEPTOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PROTEIN ANTIBODY; AUTOANTIBODY; FCGR1 PROTEIN, MOUSE; IMMUNOGLOBULIN G; MOG PROTEIN, HUMAN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM DISEASE; COCULTURE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FLOW CYTOMETRY; HUMORAL IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DEFICIENCY; FEMALE; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELOOPTIC NEUROPATHY; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIBODIES; B-LYMPHOCYTES; COCULTURE TECHNIQUES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN G; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NEUROMYELITIS OPTICA; RECEPTORS, IGG; T-LYMPHOCYTES;

EID: 84962259757     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-016-1559-8     Document Type: Article

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