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Volumn 113, Issue 12, 2016, Pages 3281-3286

Dynamic control of strand excision during human DNA mismatch repair

Author keywords

EXOI; Lynch syndrome HNPCC; MLH1 PMS2; MSH2 MSH6; Single molecule

Indexed keywords

CELL EXTRACT; DNA; DOUBLE STRANDED DNA; EXONUCLEASE; HETERODIMER; PROTEIN MSH2; PROTEIN MSH6; PROTEIN MUTL; SINGLE STRANDED DNA; SINGLE STRANDED DNA BINDING PROTEIN; ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; DNA LIGASE; G-T MISMATCH-BINDING PROTEIN; MISMATCH REPAIR PROTEIN PMS2; MLH1 PROTEIN, HUMAN; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84962240768     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1523748113     Document Type: Article
Times cited : (31)

References (40)
  • 1
    • 84946074083 scopus 로고    scopus 로고
    • Mismatch repair
    • Fishel R (2015) Mismatch repair. J Biol Chem 290(44):26395-26403.
    • (2015) J Biol Chem , vol.290 , Issue.44 , pp. 26395-26403
    • Fishel, R.1
  • 2
    • 84880918800 scopus 로고    scopus 로고
    • The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome
    • Martín-López JV, Fishel R (2013) The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome. Fam Cancer 12(2): 159-168.
    • (2013) Fam Cancer , vol.12 , Issue.2 , pp. 159-168
    • Martín-López, J.V.1    Fishel, R.2
  • 3
    • 84887491721 scopus 로고    scopus 로고
    • Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins
    • Bowen N, et al. (2013) Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins. Proc Natl Acad Sci USA 110(46): 18472-18477.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.46 , pp. 18472-18477
    • Bowen, N.1
  • 4
    • 28844503379 scopus 로고    scopus 로고
    • Human mismatch repair: Reconstitution of a nick-directed bidirectional reaction
    • Constantin N, Dzantiev L, Kadyrov FA, Modrich P (2005) Human mismatch repair: Reconstitution of a nick-directed bidirectional reaction. J Biol Chem 280(48): 39752-39761.
    • (2005) J Biol Chem , vol.280 , Issue.48 , pp. 39752-39761
    • Constantin, N.1    Dzantiev, L.2    Kadyrov, F.A.3    Modrich, P.4
  • 5
    • 0345276522 scopus 로고    scopus 로고
    • Mechanism of 5′-directed excision in human mismatch repair
    • Genschel J, Modrich P (2003) Mechanism of 5′-directed excision in human mismatch repair. Mol Cell 12(5):1077-1086.
    • (2003) Mol Cell , vol.12 , Issue.5 , pp. 1077-1086
    • Genschel, J.1    Modrich, P.2
  • 6
    • 24144447320 scopus 로고    scopus 로고
    • Reconstitution of 5′-directed human mismatch repair in a purified system
    • Zhang Y, et al. (2005) Reconstitution of 5′-directed human mismatch repair in a purified system. Cell 122(5):693-705.
    • (2005) Cell , vol.122 , Issue.5 , pp. 693-705
    • Zhang, Y.1
  • 7
    • 0027190956 scopus 로고
    • Bidirectional excision in methyl-directed mismatch repair
    • Grilley M, Griffith J, Modrich P (1993) Bidirectional excision in methyl-directed mismatch repair. J Biol Chem 268(16):11830-11837.
    • (1993) J Biol Chem , vol.268 , Issue.16 , pp. 11830-11837
    • Grilley, M.1    Griffith, J.2    Modrich, P.3
  • 8
    • 33746189409 scopus 로고    scopus 로고
    • Endonucleolytic function of MutLalpha in human mismatch repair
    • Kadyrov FA, Dzantiev L, Constantin N, Modrich P (2006) Endonucleolytic function of MutLalpha in human mismatch repair. Cell 126(2):297-308.
    • (2006) Cell , vol.126 , Issue.2 , pp. 297-308
    • Kadyrov, F.A.1    Dzantiev, L.2    Constantin, N.3    Modrich, P.4
  • 9
    • 0033621353 scopus 로고    scopus 로고
    • The RAD2 domain of human exonuclease 1 exhibits 5′ to 3′ exonuclease and flap structure-specific endonuclease activities
    • Lee BI, Wilson DM, 3rd (1999) The RAD2 domain of human exonuclease 1 exhibits 5′ to 3′ exonuclease and flap structure-specific endonuclease activities. J Biol Chem 274(53):37763-37769.
    • (1999) J Biol Chem , vol.274 , Issue.53 , pp. 37763-37769
    • Lee, B.I.1    Wilson, D.M.2
  • 10
    • 79955466020 scopus 로고    scopus 로고
    • In vitro studies of DNA mismatch repair proteins
    • Geng H, et al. (2011) In vitro studies of DNA mismatch repair proteins. Anal Biochem 413(2):179-184.
    • (2011) Anal Biochem , vol.413 , Issue.2 , pp. 179-184
    • Geng, H.1
  • 11
    • 0028941627 scopus 로고
    • Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
    • Li G-M, Modrich P (1995) Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci USA 92(6):1950-1954.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.6 , pp. 1950-1954
    • Li, G.-M.1    Modrich, P.2
  • 12
    • 34548783162 scopus 로고    scopus 로고
    • Coupling distant sites in DNA during DNA mismatch repair
    • Kolodner RD, Mendillo ML, Putnam CD (2007) Coupling distant sites in DNA during DNA mismatch repair. Proc Natl Acad Sci USA 104(32):12953-12954.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.32 , pp. 12953-12954
    • Kolodner, R.D.1    Mendillo, M.L.2    Putnam, C.D.3
  • 14
    • 31844453991 scopus 로고    scopus 로고
    • DNA primase acts as a molecular brake in DNA replication
    • Lee JB, et al. (2006) DNA primase acts as a molecular brake in DNA replication. Nature 439(7076):621-624.
    • (2006) Nature , vol.439 , Issue.7076 , pp. 621-624
    • Lee, J.B.1
  • 15
    • 0041821716 scopus 로고    scopus 로고
    • Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder
    • van Oijen AM, et al. (2003) Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder. Science 301(5637):1235-1238.
    • (2003) Science , vol.301 , Issue.5637 , pp. 1235-1238
    • Van Oijen, A.M.1
  • 16
    • 85015087906 scopus 로고    scopus 로고
    • Ten years of tension: Single-molecule DNA mechanics
    • Bustamante C, Bryant Z, Smith SB (2003) Ten years of tension: Single-molecule DNA mechanics. Nature 421(6921):423-427.
    • (2003) Nature , vol.421 , Issue.6921 , pp. 423-427
    • Bustamante, C.1    Bryant, Z.2    Smith, S.B.3
  • 17
    • 79953838905 scopus 로고    scopus 로고
    • Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family
    • Orans J, et al. (2011) Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family. Cell 145(2):212-223.
    • (2011) Cell , vol.145 , Issue.2 , pp. 212-223
    • Orans, J.1
  • 18
    • 0036121372 scopus 로고    scopus 로고
    • Partial reconstitution of human DNA mismatch repair in vitro: Characterization of the role of human replication protein A
    • Ramilo C, et al. (2002) Partial reconstitution of human DNA mismatch repair in vitro: Characterization of the role of human replication protein A. Mol Cell Biol 22(7): 2037-2046.
    • (2002) Mol Cell Biol , vol.22 , Issue.7 , pp. 2037-2046
    • Ramilo, C.1
  • 19
    • 84876896603 scopus 로고    scopus 로고
    • Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50- Xrs2 to DNA end resection
    • Cannavo E, Cejka P, Kowalczykowski SC (2013) Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50- Xrs2 to DNA end resection. Proc Natl Acad Sci USA 110(18):E1661-E1668.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.18 , pp. E1661-E1668
    • Cannavo, E.1    Cejka, P.2    Kowalczykowski, S.C.3
  • 20
    • 79952363840 scopus 로고    scopus 로고
    • MutS switches between two fundamentally distinct clamps during mismatch repair
    • Jeong C, et al. (2011) MutS switches between two fundamentally distinct clamps during mismatch repair. Nat Struct Mol Biol 18(3):379-385.
    • (2011) Nat Struct Mol Biol , vol.18 , Issue.3 , pp. 379-385
    • Jeong, C.1
  • 21
    • 84904755513 scopus 로고    scopus 로고
    • Single-molecule views of MutS on mismatched DNA
    • Lee JB, et al. (2014) Single-molecule views of MutS on mismatched DNA. DNA Repair (Amst) 20:82-93.
    • (2014) DNA Repair (Amst) , vol.20 , pp. 82-93
    • Lee, J.B.1
  • 22
    • 84862208973 scopus 로고    scopus 로고
    • Plasmodium falciparum SSB tetramer wraps single-stranded DNA with similar topology but opposite polarity to E. Coli SSB
    • Antony E, Weiland EA, Korolev S, Lohman TM (2012) Plasmodium falciparum SSB tetramer wraps single-stranded DNA with similar topology but opposite polarity to E. coli SSB. J Mol Biol 420(4-5):269-283.
    • (2012) J Mol Biol , vol.420 , Issue.4-5 , pp. 269-283
    • Antony, E.1    Weiland, E.A.2    Korolev, S.3    Lohman, T.M.4
  • 23
    • 84867693856 scopus 로고    scopus 로고
    • Structure and conformational change of a replication protein A heterotrimer bound to ssDNA
    • Fan J, Pavletich NP (2012) Structure and conformational change of a replication protein A heterotrimer bound to ssDNA. Genes Dev 26(20):2337-2347.
    • (2012) Genes Dev , vol.26 , Issue.20 , pp. 2337-2347
    • Fan, J.1    Pavletich, N.P.2
  • 24
    • 0032584384 scopus 로고    scopus 로고
    • Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha
    • Genschel J, Littman SJ, Drummond JT, Modrich P (1998) Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. J Biol Chem 273(31):19895-19901.
    • (1998) J Biol Chem , vol.273 , Issue.31 , pp. 19895-19901
    • Genschel, J.1    Littman, S.J.2    Drummond, J.T.3    Modrich, P.4
  • 25
    • 84863534989 scopus 로고    scopus 로고
    • ATP alters the diffusion mechanics of MutS on mismatched DNA
    • Cho WK, et al. (2012) ATP alters the diffusion mechanics of MutS on mismatched DNA. Structure 20(7):1264-1274.
    • (2012) Structure , vol.20 , Issue.7 , pp. 1264-1274
    • Cho, W.K.1
  • 26
    • 84868514786 scopus 로고    scopus 로고
    • Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair
    • Gorman J, et al. (2012) Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair. Proc Natl Acad Sci USA 109(45):E3074-E3083.
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.45 , pp. E3074-E3083
    • Gorman, J.1
  • 27
    • 0033083040 scopus 로고    scopus 로고
    • HMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
    • Gradia S, et al. (1999) hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA. Mol Cell 3(2):255-261.
    • (1999) Mol Cell , vol.3 , Issue.2 , pp. 255-261
    • Gradia, S.1
  • 28
    • 79956335271 scopus 로고    scopus 로고
    • Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity
    • Hwang H, Kim H, Myong S (2011) Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity. Proc Natl Acad Sci USA 108(18): 7414-7418.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.18 , pp. 7414-7418
    • Hwang, H.1    Kim, H.2    Myong, S.3
  • 29
    • 33749134033 scopus 로고    scopus 로고
    • A dynamic model for replication protein A (RPA) function in DNA processing pathways
    • Fanning E, Klimovich V, Nager AR (2006) A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res 34(15):4126-4137.
    • (2006) Nucleic Acids Res , vol.34 , Issue.15 , pp. 4126-4137
    • Fanning, E.1    Klimovich, V.2    Nager, A.R.3
  • 30
    • 0041669372 scopus 로고    scopus 로고
    • The coordinated functions of the E. Coli MutS and MutL proteins in mismatch repair
    • Acharya S, Foster PL, Brooks P, Fishel R (2003) The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. Mol Cell 12(1):233-246.
    • (2003) Mol Cell , vol.12 , Issue.1 , pp. 233-246
    • Acharya, S.1    Foster, P.L.2    Brooks, P.3    Fishel, R.4
  • 31
    • 0032109778 scopus 로고    scopus 로고
    • Chromosomal rearrangements occur in S. Cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by doublestrand- break repair
    • Chen C, Umezu K, Kolodner RD (1998) Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by doublestrand- break repair. Mol Cell 2(1):9-22.
    • (1998) Mol Cell , vol.2 , Issue.1 , pp. 9-22
    • Chen, C.1    Umezu, K.2    Kolodner, R.D.3
  • 32
    • 0035979993 scopus 로고    scopus 로고
    • The interaction of DNA mismatch repair proteins with human exonuclease i
    • Schmutte C, Sadoff MM, Shim KS, Acharya S, Fishel R (2001) The interaction of DNA mismatch repair proteins with human exonuclease I. J Biol Chem 276(35):33011-33018.
    • (2001) J Biol Chem , vol.276 , Issue.35 , pp. 33011-33018
    • Schmutte, C.1    Sadoff, M.M.2    Shim, K.S.3    Acharya, S.4    Fishel, R.5
  • 33
    • 34249066085 scopus 로고    scopus 로고
    • PCNA, the maestro of the replication fork
    • Moldovan GL, Pfander B, Jentsch S (2007) PCNA, the maestro of the replication fork. Cell 129(4):665-679.
    • (2007) Cell , vol.129 , Issue.4 , pp. 665-679
    • Moldovan, G.L.1    Pfander, B.2    Jentsch, S.3
  • 34
    • 84940875569 scopus 로고    scopus 로고
    • MutL traps MutS at a DNA mismatch
    • Qiu R, et al. (2015) MutL traps MutS at a DNA mismatch. Proc Natl Acad Sci USA 112(35):10914-10919.
    • (2015) Proc Natl Acad Sci USA , vol.112 , Issue.35 , pp. 10914-10919
    • Qiu, R.1
  • 35
    • 79951500316 scopus 로고    scopus 로고
    • Okazaki fragment maturation: Nucleases take centre stage
    • Zheng L, Shen B (2011) Okazaki fragment maturation: Nucleases take centre stage. J Mol Cell Biol 3(1):23-30.
    • (2011) J Mol Cell Biol , vol.3 , Issue.1 , pp. 23-30
    • Zheng, L.1    Shen, B.2
  • 36
    • 0030806219 scopus 로고    scopus 로고
    • Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2
    • Tishkoff DX, et al. (1997) Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci USA 94(14):7487-7492.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.14 , pp. 7487-7492
    • Tishkoff, D.X.1
  • 37
    • 84863338643 scopus 로고    scopus 로고
    • RAD51 protein ATP cap regulates nucleoprotein filament stability
    • Amunugama R, et al. (2012) RAD51 protein ATP cap regulates nucleoprotein filament stability. J Biol Chem 287(12):8724-8736.
    • (2012) J Biol Chem , vol.287 , Issue.12 , pp. 8724-8736
    • Amunugama, R.1
  • 38
    • 81155123697 scopus 로고    scopus 로고
    • Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6
    • Heinen CD, et al. (2011) Human MSH2 (hMSH2) protein controls ATP processing by hMSH2-hMSH6. J Biol Chem 286(46):40287-40295.
    • (2011) J Biol Chem , vol.286 , Issue.46 , pp. 40287-40295
    • Heinen, C.D.1
  • 39
    • 78649757433 scopus 로고    scopus 로고
    • Single-molecule analysis reveals the kinetics and physiological relevance of MutL-ssDNA binding
    • Park J, et al. (2010) Single-molecule analysis reveals the kinetics and physiological relevance of MutL-ssDNA binding. PLoS One 5(11):e15496.
    • (2010) PLoS One , vol.5 , Issue.11 , pp. e15496
    • Park, J.1
  • 40
    • 84875478557 scopus 로고    scopus 로고
    • Tri-track: Free software for large-scale particle tracking
    • Vallotton P, Olivier S (2013) Tri-track: Free software for large-scale particle tracking. Microsc Microanal 19(2):451-460.
    • (2013) Microsc Microanal , vol.19 , Issue.2 , pp. 451-460
    • Vallotton, P.1    Olivier, S.2


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