Impact of sulfadoxine-pyrimethamine resistance on effectiveness of intermittent preventive therapy for Malaria in pregnancy at clearing infections and preventing low birth weight

Clinical Infectious Diseases

Volumn 62, Issue 3, 2016, Pages 323-333

  Desai, Meghna ^a,b   Gutman, Julie ^a   Taylor, Steve M ^c,d   Wiegand, Ryan E ^a   Khairallah, Carole ^e   Kayentao, Kassoum ^e,f   Ouma, Peter ^b   Coulibaly, Sheick O ^g   Kalilani, Linda ^h   Mace, Kimberly E ^a   Arinaitwe, Emmanuel ⁱ   Mathanga, Don P ^h   Doumbo, Ogobara ^f   Otieno, Kephas ^b   Edgar, Dabira ^g   Chaluluka, Ebbie ^h   Kamuliwo, Mulakwa ^j   Ades, Veronica ^k   Skarbinski, Jacek ^a   Shi, Ya Ping ^a   Magnussen, Pascal ^l   Meshnick, Steve ^d   Ter Kuile, Feiko O ^e   more..

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d University of North Carolina at Chapel Hill   (United States)

^e LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^f Sociétés   (Mali)

^g UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^h UNIVERSITY OF MALAWI   (Malawi)

ⁱ INFECTIOUS DISEASES RESEARCH COLLABORATION   (Uganda)

^j National Malaria Control Centre   (Zambia)

^k NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^l UNIVERSITY OF COPENHAGEN   (Denmark)

more..

Author keywords

effectiveness; intermittent preventive treatment; malaria in pregnancy; sulfadoxine pyrimethamine resistance

Indexed keywords

PYRIMETHAMINE PLUS SULFADOXINE; ANTIMALARIAL AGENT; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATION; FANASIL, PYRIMETHAMINE DRUG COMBINATION; MUTANT PROTEIN; PYRIMETHAMINE; SULFADOXINE;

ADULT; ARTICLE; BIRTH WEIGHT; DELIVERY; DISEASE ASSOCIATION; DRUG EFFICACY; FEMALE; FOLLOW UP; HEMOGLOBIN BLOOD LEVEL; HUMAN; IN VIVO STUDY; INFECTION PREVENTION; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALARIA; MATERNAL BLOOD; MULTIDRUG RESISTANCE; PARASITE CLEARANCE; PREGNANT WOMAN; PREVALENCE; PRIORITY JOURNAL; RECURRENT DISEASE; RISK ASSESSMENT; RISK REDUCTION; TREATMENT FAILURE; AFRICA SOUTH OF THE SAHARA; AMINO ACID SUBSTITUTION; COMPLICATION; DRUG COMBINATION; DRUG RESISTANCE; DRUG THERAPY; ENZYMOLOGY; EPIDEMIOLOGY; GENETICS; NEWBORN; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PROCEDURES; PROSPECTIVE STUDY; TREATMENT OUTCOME; YOUNG ADULT;

ADULT; AFRICA SOUTH OF THE SAHARA; AMINO ACID SUBSTITUTION; ANTIMALARIALS; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATIONS; DRUG RESISTANCE; DRUG THERAPY; FEMALE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; MALARIA; MUTANT PROTEINS; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PROSPECTIVE STUDIES; PYRIMETHAMINE; SULFADOXINE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84962234990     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/civ881     Document Type: Article

References (38)

1. Dellicour S, Tatem AJ, Guerra CA, Snow PR, ter Kuile FO. Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study. PLoS Med 2010; 7: e1000221
2. Desai M, ter Kuile FO, Nosten F., et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 2007; 7: 93-104
3. World Health Organization. A strategic framework for malaria prevention and control during pregnancy in the African Region. Brazzaville: WHO Regional Office for Africa, 2004
4. ter Kuile FO, Van Eijk AM, Filler SJ. Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic review. JAMA 2007; 297: 2603-16
5. Eisele TP, Larsen DA, Anglewicz PA., et al. Malaria prevention in pregnancy, birthweight, and neonatal mortality: ameta-Analysis of 32 national cross-sectional datasets in Africa. Lancet Infect Dis 2012; 12: 942-9
6. World Health Organization Policy Advisory Committee and Secretariat. Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of September 2012 meeting. Malar J 2012; 11: 424
7. Kayentao K, Garner P, Van Eijk AM., et al. Intermittent preventive therapy for malaria during pregnancy using 2 vs 3 or more doses of sulfadoxine-pyrimethamine and risk of low birth weight in Africa: systematic review and meta-Analysis. JAMA 2013; 309: 594-604
8. Van Eijk AM, Hill J, Alegana VA., et al. Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey data. Lancet Infect Dis 2011; 11: 190-207
9. Van Eijk AM, Hill J, Larsen DA., et al. Coverage of intermittent preventive treatment and insecticide-Treated nets for the control of malaria during pregnancy in sub-Saharan Africa: a synthesis and meta-Analysis of national survey data, 2009-Lancet Infect Dis 2013; 13: 1029-42
10. Harrington WE, Mutabingwa TK, Muehlenbachs A., et al. Competitive facilitation of drug-resistant Plasmodium falciparum malaria parasites in pregnant women who receive preventive treatment. Proc Natl Acad Sci U S A 2009; 106: 9027-32
11. Minja DT, Schmiegelow C, Mmbando B., et al. Plasmodium falciparum mutant haplotype infection during pregnancy associated with reduced birthweight, Tanzania. Emerg Infect Dis 2013; 19: 1446-54
12. Roper C, Pearce R, Nair S, Sharp B, Nosten F, Anderson T. Intercontinental spread of pyrimethamine-resistant malaria. Science 2004; 305: 1124
13. Wootton JC, Feng X, Ferdig MT., et al. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature 2002; 418: 320-3
14. Arinaitwe E, Ades V, Walakira A., et al. Intermittent preventive therapy with sulfadoxine-pyrimethamine for malaria in pregnancy: a cross-sectional study from Tororo, Uganda. PLoS One 2013; 8: e73073
15. Gutman J, Mwandama D, Wiegand RE, Ali D, Mathanga DP, Skarbinski J. Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on maternal and birth outcomes in Machinga district, Malawi. J Infect Dis 2013; 208: 907-16
16. Coulibaly SO, Kayentao K, Taylor S., et al. Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study. Malar J 2014; 13: 41
17. Kalilani L, Taylor S, Madanitsa M., et al. Waning effectiveness of intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) in the presence of high SP resistance in Malawi [abstract 1179]. In: American Society of Tropical Medicine and Hygiene, 60th Annual Meeting, Philadelphia, PA, 4-8 December 2011
18. Iriemenam NC, Shah M, Gatei W., et al. Temporal trends of sulphadoxinepyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya. Malar J 2012; 11: 134
19. Tan KR, Katalenich BL, Mace KE., et al. Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia. Malar J 2014; 13: 227
20. Mace KE, Chalwe V, Katalenich BL., et al. Evaluation of sulphadoxinepyrimethamine for intermittent preventive treatment of malaria in pregnancy: a retrospective birth outcomes study in Mansa, Zambia. Malar J 2015; 14: 69
21. Gutman J, Mwandama D, Wiegand RE., et al. In vivo efficacy of sulphadoxinepyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi. Malar J 2015; 14: 197
22. United States Pharmacopeia and National Formulary (USP 27-NF 22). Vol. 2. Rockville, MD: US Pharmacopeia Convention, 2004: 1744-5
23. World Health Organization. Methods and techniques for clinical trials on antimalarial drug efficacy: genotyping to identify parasite populations. Geneva, Switzerland: WHO, 2008
24. Taylor SM, Parobek CM, Aragam N., et al. Pooled deep sequencing of Plasmodium falciparum isolates: an efficient and scalable tool to quantify prevailing malaria drug-resistance genotypes. J Infect Dis 2013; 208: 1998-2006
25. Landis SH, Ananth CV, Lokomba V., et al. Ultrasound-derived fetal size nomogram for a sub-Saharan African population: a longitudinal study. Ultrasound Obstet Gynecol 2009; 34: 379-86
26. WorldWide Antimalarial Resistance Network (WWARN). Clinical module. Data management and statistical analysis plan. Oxford: WWARN, 2011
27. Rosenbaum P, Rubin DB. Reducing bias in observational studies using subclassification on the propensity score. J Am Stat Assoc 1984; 79: 516-24
28. McCaffrey DF, Ridgeway G, Morral AR. Propensity score estimation with boosted regression for evaluating causal effects in observational studies. Psychol Methods 2004; 9: 403-25
29. Gething PW, Patil AP, Smith DL., et al. A new world malaria map: Plasmodium falciparum endemicity in 2010. Malar J 2011; 10: 378
30. Rogerson SJ, Pollina E, Getachew A, Tadesse E, Lema VM, Molyneux ME. Placental monocyte infiltrates in response to Plasmodium falciparum malaria infection and their association with adverse pregnancy outcomes. Am J Trop Med Hyg 2003; 68: 115-9
31. Capan M, Mombo-Ngoma G, Makristathis A, Ramharter M. Anti-bacterial activity of intermittent preventive treatment of malaria in pregnancy: comparative in vitro study of sulphadoxine-pyrimethamine, mefloquine, and azithromycin. Malar J 2010; 9: 303
32. Gesase S, Gosling RD, Hashim R., et al. High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at codon 581. PLoS One 2009; 4: e4569
33. Gutman J, Kalilani L, Taylor S., et al. The A581G mutation in the gene encoding Plasmodium falciparum dihydropteroate synthetase reduces the effectiveness of sulfadoxine-pyrimethamine preventive therapy in Malawian pregnant women. J Infect Dis 2015; 211: 1997-2005
34. Metgud CS, Naik VA, Mallapur MD. Factors affecting birth weight of a newborn- a community based study in rural Karnataka, India. PLoS One 2012; 7: e40040
35. Van Eijk AM, Ouma PO, Williamson J., et al. Plasma folate level and high-dose folate supplementation predict sulfadoxine-pyrimethamine treatment failure in pregnant women in western Kenya who have uncomplicated malaria. J Infect Dis 2008; 198: 1550-3
36. Alifrangis M, Nag S, Schousboe ML., et al. Independent origin of Plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia. Emerg Infect Dis 2014; 20: 1280-6
37. Naidoo I, Roper C. Mapping partially resistant , fully resistant , and super resistant malaria. Trends Parasitol 2013; 29: 505-15
38. Taylor SM, Antonia AL, Harrington WE., et al. Independent lineages of highly sulfadoxine-resistant Plasmodium falciparum haplotypes, eastern Africa. Emerg Infect Dis 2014; 20: 1140-8