Aging-related renal injury and inflammation are associated with downregulation of Klotho and induction of RIG-I/NF-κB signaling pathway in senescence-accelerated mice

Aging Clinical and Experimental Research

Volumn 28, Issue 1, 2016, Pages 69-76

  Zeng, Yi ^a   Wang, Ping Han ^a   Zhang, Mao ^a   Du, Jun Rong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Aging; Inflammation; Kidney injury; Klotho; NF B; RIG I

Indexed keywords

ALBUMIN; CREATININE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; KLOTHO PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; TUMOR NECROSIS FACTOR ALPHA; BETA GLUCURONIDASE; DDX58 PROTEIN, MOUSE; DEAD BOX PROTEIN; NFKB1 PROTEIN, MOUSE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; DOWN REGULATION; GLOMERULOSCLEROSIS; INFLAMMATION; INFLAMMATORY CELL; INTERSTITIAL NEPHRITIS; KIDNEY INJURY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE ACCELERATED MOUSE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; FEMALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RENAL INSUFFICIENCY;

AGING; ANIMALS; DEAD-BOX RNA HELICASES; DOWN-REGULATION; FEMALE; GLUCURONIDASE; INFLAMMATION; MALE; MICE; NF-KAPPA B P50 SUBUNIT; RENAL INSUFFICIENCY; SIGNAL TRANSDUCTION;

EID: 84962172891     PISSN: 15940667     EISSN: 17208319     Source Type: Journal    
DOI: 10.1007/s40520-015-0371-y     Document Type: Article

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