Liver transplantation for nonalcoholic steatohepatitis in young patients

Transplant International

Volumn 29, Issue 4, 2016, Pages 418-424

  Alkhouri, Naim ^a   Hanouneh, Ibrahim A ^a   Zein, Nizar N ^a   Lopez, Rocio ^a   Kelly, Dympna ^a   Eghtesad, Bijan ^a   Fung, John J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

children; cryptogenic cirrhosis; liver transplantation; nonalcoholic steatohepatitis; young adults

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BODY MASS; CAUCASIAN; CHILD; END STAGE LIVER DISEASE; FEMALE; FOLLOW UP; GRAFT SURVIVAL; HUMAN; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; RECURRENT DISEASE; RETRANSPLANTATION; SURVIVAL TIME; UNITED STATES; YOUNG ADULT; COHORT ANALYSIS; COMPLICATION; DISEASE COURSE; FACTUAL DATABASE; INSULIN RESISTANCE; KAPLAN MEIER METHOD; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; PRESCHOOL CHILD; TREATMENT OUTCOME;

ADOLESCENT; ADULT; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DATABASES, FACTUAL; DISEASE PROGRESSION; END STAGE LIVER DISEASE; FEMALE; GRAFT SURVIVAL; HUMANS; INSULIN RESISTANCE; KAPLAN-MEIER ESTIMATE; LIVER TRANSPLANTATION; MALE; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84962142449     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12694     Document Type: Article

References (24)

1. Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C,. Prevalence of fatty liver in children and adolescents. Pediatrics 2006; 118: 1388.
2. Williams CD, Stengel J, Asike MI, et al,. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 2011; 140: 124.
3. Aggarwal A, Puri K, Thangada S, Zein N, Alkhouri N,. Nonalcoholic fatty liver disease in children: recent practice guidelines, where do they take us?. Curr Pediatr Rev 2014; 10: 151.
4. Rafiq N, Bai C, Fang Y, et al,. Long-term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol 2009; 7: 234.
5. Charlton M,. Evolving aspects of liver transplantation for nonalcoholic steatohepatitis. Curr Opin Organ Transplant 2013; 18: 251.
6. Charlton MR, Burns JM, Pedersen RA, Watt KD, Heimbach JK, Dierkhising RA,. Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States. Gastroenterology 2011; 141: 1249.
7. Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB, Angulo P,. The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut 2009; 58: 1538.
8. Koskinen J, Magnussen CG, Kahonen M, et al,. Association of liver enzymes with metabolic syndrome and carotid atherosclerosis in young adults. The Cardiovascular Risk in Young Finns Study. Ann Med 2012; 44: 187.
9. Yamazaki Y, Kakizaki S, Sohara N, et al,. Hepatocellular carcinoma in young adults: the clinical characteristics, prognosis, and findings of a patient survival analysis. Dig Dis Sci 2007; 52: 1103.
10. Wong RJ, Cheung R, Ahmed A,. Nonalcoholic steatohepatitis is the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the U.S. Hepatology 2014; 59: 2188.
11. Welsh JA, Karpen S, Vos MB,. Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988-1994 to 2007-2010. J Pediatr 2013; 162: 496.
12. Molleston JP, White F, Teckman J, Fitzgerald JF,. Obese children with steatohepatitis can develop cirrhosis in childhood. Am J Gastroenterol 2002; 97: 2460.
13. Agopian VG, Kaldas FM, Hong JC, et al,. Liver transplantation for nonalcoholic steatohepatitis: the new epidemic. Ann Surg 2012; 256: 624.
14. Alkhouri N, Sedki E, Alisi A, et al,. Combined paediatric NAFLD fibrosis index and transient elastography to predict clinically significant fibrosis in children with fatty liver disease. Liver Int 2013; 33: 79.
15. Xanthakos SA, Podberesky DJ, Serai SD, et al,. Use of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease. J Pediatr 2014; 164: 186.
16. Loomba R, Wolfson T, Ang B, et al,. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology 2014; 60: 1920.
17. Sanyal AJ, Chalasani N, Kowdley KV, et al,. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med 2010; 362: 1675.
18. Mudaliar S, Henry RR, Sanyal AJ, et al,. Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease. Gastroenterology 2013; 145: 574.
19. Lavine JE, Schwimmer JB, Van Natta ML, et al,. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA 2011; 305: 1659.
20. Contos MJ, Cales W, Sterling RK, et al,. Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis. Liver Transpl 2001; 7: 363.
21. Pagadala M, Dasarathy S, Eghtesad B, McCullough AJ,. Posttransplant metabolic syndrome: an epidemic waiting to happen. Liver Transpl 2009; 15: 1662.
22. Hanouneh IA, Zein NN,. Metabolic syndrome and liver transplantation. Minerva Gastroenterol Dietol 2010; 56: 297.
23. Heimbach JK, Watt KD, Poterucha JJ, et al,. Combined liver transplantation and gastric sleeve resection for patients with medically complicated obesity and end-stage liver disease. Am J Transplant 2013; 13: 363.
24. Vajro P, Lenta S, Socha P, et al,. Diagnosis of nonalcoholic fatty liver disease in children and adolescents: position paper of the ESPGHAN Hepatology Committee. J Pediatr Gastroenterol Nutr 2012; 54: 700.