A rabies vaccine adjuvanted with saponins from leaves of the soap tree (Quillaja brasiliensis) induces specific immune responses and protects against lethal challenge

Vaccine

Volumn 34, Issue 20, 2016, Pages 2305-2311

  Yendo, Anna Carolina A ^a   de Costa, Fernanda ^a   Cibulski, Samuel P ^b,c   Teixeira, Thais F ^b,c   Colling, Luana C ^a   Mastrogiovanni, Mauricio ^d   Soulé, Silvia ^d   Roehe, Paulo M ^b,c   Gosmann, Grace ^a   Ferreira, Fernando A ^d   Fett Neto, Arthur G ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b Veterinary Research Institute Desidério Finamor   (Brazil)

^c Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Adjuvant; Challenge; Protection; Quillaja brasiliensis; Rabies virus; Saponin

Indexed keywords

ALUMINUM POTASSIUM SULFATE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; QUIL A; RABIES VACCINE; SAPONIN; SAPONIN ADJUVANTED RABIES VACCINE; UNCLASSIFIED DRUG; VIRUS RNA; IMMUNOLOGICAL ADJUVANT; PLANT EXTRACT; QUILLAJA SAPONIN; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; NONHUMAN; PLANT LEAF; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUILLAJA; QUILLAJA BRASILIENSIS; RABIES; ANIMAL; BLOOD; BRAIN; CHEMISTRY; COMPARATIVE STUDY; IMMUNOLOGY; ISOLATION AND PURIFICATION; VIROLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; BRAIN; FEMALE; IMMUNOGLOBULIN G; MICE; PLANT EXTRACTS; PLANT LEAVES; QUILLAJA; QUILLAJA SAPONINS; RABIES; RABIES VACCINES; RNA, VIRAL;

EID: 84962054158     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2016.03.070     Document Type: Article

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