Hyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via μ-calpain activation

Diabetes

Volumn 64, Issue 3, 2015, Pages 947-959

  Cheng, Zhongjian ^a   Jiang, Xiaohua ^a   Pansuria, Meghana ^a   Fang, Pu ^a   Mai, Jietang ^a   Mallilankaraman, Karthik ^a   Gandhirajan, Rajesh Kumar ^a   Eguchi, Satoru ^a   Scalia, Rosario ^a   Madesh, Muniswamy ^a   Yang, Xiaofeng ^a   Wang, Hong ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALPAIN 1; CALPASTATIN; CYSTATHIONINE BETA SYNTHASE; CYSTEINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; METHIONINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SMALL INTERFERING RNA; STREPTOZOCIN; SUPEROXIDE; THREONINE; CALPAIN; GLUCOSE BLOOD LEVEL; MU-CALPAIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; BIOAVAILABILITY; BODY WEIGHT; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYPERGLYCEMIA; HYPERHOMOCYSTEINEMIA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; BLOOD GLUCOSE; CALPAIN; CELLS, CULTURED; CYSTATHIONINE BETA-SYNTHASE; ENDOTHELIAL CELLS; HUMANS; HYPERGLYCEMIA; HYPERHOMOCYSTEINEMIA; MALE; MICE; MICE, MUTANT STRAINS; NITRIC OXIDE SYNTHASE TYPE III; SUPEROXIDES;

EID: 84962054016     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0784     Document Type: Article

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