In vivo risk evaluation of carbon-coated iron carbide nanoparticles based on short- and long-term exposure scenarios

Nanomedicine

Volumn 11, Issue 7, 2016, Pages 783-796

  Herrmann, Inge K ^a,b,f   Beck Schimmer, Beatrice ^a,b   Schumacher, Christoph M ^c   Gschwind, Sabrina ^d   Kaech, Andres ^b   Ziegler, Urs ^b   Clavien, Pierre Alain ^e   Günther, Detlef ^d   Stark, Wendelin J ^c   Graf, Rolf ^e   Schlegel, Andrea A ^e  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c ETH ZURICH   (Switzerland)

^d LABORATORY OF INORGANIC CHEMISTRY   (Switzerland)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^f SWISS FEDERAL LABORATORIES FOR MATERIALS SCIENCE AND TECHNOLOGY   (Switzerland)

Author keywords

blood purification; long term study; magnetic nanoparticles; targeted drug delivery

Indexed keywords

ALBUMIN; BILIRUBIN; CARBON; CREATININE; GLUCOSE; HEMOGLOBIN; IMMUNOGLOBULIN G; INTERLEUKIN 6; IRON CARBIDE NANOPARTICLE; MACROGOL; MAGNETIC NANOPARTICLE; NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; BIOCOMPATIBLE COATED MATERIAL; DRUG CARRIER; INORGANIC COMPOUND; IRON CARBIDE; IRON DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BODY WEIGHT; CARCINOGENESIS; ERYTHROCYTE COUNT; FEMALE; FIBROSIS; IN VIVO STUDY; INFLAMMATION; KIDNEY; LEUKOCYTE COUNT; LIVER; LONG TERM EXPOSURE; LUNG; MACROPHAGE; MALE; MASS SPECTROMETRY; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM; SMALL INTESTINE; SPLEEN; THROMBOCYTE COUNT; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; MAGNET; METABOLISM; ULTRASTRUCTURE;

ANIMALS; CARBON; CARBON COMPOUNDS, INORGANIC; COATED MATERIALS, BIOCOMPATIBLE; DRUG CARRIERS; FEMALE; IRON COMPOUNDS; LIVER; LUNG; MAGNETS; MALE; MICE; MICE, INBRED C57BL; NANOPARTICLES;

EID: 84962045128     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.16.22     Document Type: Article

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