A basis for rapid clearance of circulating ring-stage malaria parasites by the spiroindolone KAE609

Journal of Infectious Diseases

Volumn 213, Issue 1, 2016, Pages 100-104

  Zhang, Rou ^a   Suwanarusk, Rossarin ^b   Malleret, Benoit ^a,b   Cooke, Brian M ^c   Nosten, Francois ^d,e,f   Lau, Yee Ling ^g   Dao, Ming ^h   Lim, Chwee Teck ^a   Renia, Laurent ^b   Tan, Kevin Shyong Wei ^a   Russell, Bruce ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c MONASH UNIVERSITY   (Australia)

^d SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^e MAHIDOL UNIVERSITY   (Thailand)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g UNIVERSITY OF MALAYA   (Malaysia)

^h Massachusetts Institute of Technology   (United States)

Author keywords

Plasmodium vivax; Plasmodium falciparum; malaria; red blood cell; spiroindolones; KAE609

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE 4; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE 4; ARTESUNATE; CIPARGAMIN; SODIUM ION; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; INDOLE DERIVATIVE; SPIRO COMPOUND;

ACCELERATED SPLENIC CLEARANCE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ERYTHROCYTE; FLOW KINETICS; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MALARIA FALCIPARUM; NONHUMAN; OPEN STUDY; OSMOSIS; PARASITE CLEARANCE; PHASE 2 CLINICAL TRIAL (TOPIC); PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; PRIORITY JOURNAL; SODIUM TRANSPORT; DRUG EFFECTS; GENETICS; PARASITOLOGY;

ANTIMALARIALS; ERYTHROCYTES; HUMANS; INDOLES; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; SPIRO COMPOUNDS;

EID: 84962010370     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv358     Document Type: Article

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