메뉴 건너뛰기




Volumn 36, Issue 13, 2016, Pages 3811-3820

Deficiency of the survival of motor neuron protein impairs mrna localization and local translation in the growth cone of motor neurons

Author keywords

GAP43; Local translation; Motor neuron; RNA trafficking; SMA; SMN

Indexed keywords

ELAV LIKE PROTEIN 4; INSULIN LIKE GROWTH FACTOR 2 MRNA BINDING PROTEIN 1; MESSENGER RNA; NEUROMODULIN; PROTEIN; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG; ACTIN; ELAVL4 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; IMP1 PROTEIN, MOUSE; RNA BINDING PROTEIN; SMALL INTERFERING RNA; SMN2 PROTEIN, HUMAN; SURVIVAL MOTOR NEURON PROTEIN 2;

EID: 84961992254     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2396-15.2016     Document Type: Article
Times cited : (122)

References (61)
  • 1
    • 0028866034 scopus 로고
    • Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice
    • CrossRef Medline
    • Aigner L, Arber S, Kapfhammer JP, Laux T, Schneider C, Botteri F, Brenner HR, Caroni P (1995) Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell 83:269–278. CrossRef Medline
    • (1995) Cell , vol.83 , pp. 269-278
    • Aigner, L.1    Arber, S.2    Kapfhammer, J.P.3    Laux, T.4    Schneider, C.5    Botteri, F.6    Brenner, H.R.7    Caroni, P.8
  • 4
    • 33846162752 scopus 로고    scopus 로고
    • Dynamic association with polysomes during P19 neuronal differentiation and an untranslatedregion- dependent translation regulation of the tau mRNA by the tau mRNA-associated proteins IMP1, HuD, and G3BP1
    • CrossRef Medline
    • Atlas R, Behar L, Sapoznik S, Ginzburg I (2007) Dynamic association with polysomes during P19 neuronal differentiation and an untranslatedregion- dependent translation regulation of the tau mRNA by the tau mRNA-associated proteins IMP1, HuD, and G3BP1. J Neurosci Res 85: 173–183. CrossRef Medline
    • (2007) J Neurosci Res , vol.85 , pp. 173-183
    • Atlas, R.1    Behar, L.2    Sapoznik, S.3    Ginzburg, I.4
  • 5
    • 27144444845 scopus 로고    scopus 로고
    • Toward an assembly line for U7 snRNPs: Interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes
    • CrossRef Medline
    • Azzouz TN, Pillai RS, Däpp C, Chari A, Meister G, Kambach C, Fischer U, Schümperli D (2005) Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. J Biol Chem 280:34435–34440. CrossRef Medline
    • (2005) J Biol Chem , vol.280 , pp. 34435-34440
    • Azzouz, T.N.1    Pillai, R.S.2    Däpp, C.3    Chari, A.4    Meister, G.5    Kambach, C.6    Fischer, U.7    Schümperli, D.8
  • 7
    • 75649131837 scopus 로고    scopus 로고
    • Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets
    • CrossRef Medline
    • Bolognani F, Contente-Cuomo T, Perrone-Bizzozero NI (2010) Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets. Nucleic Acids Res 38:117–130. CrossRef Medline
    • (2010) Nucleic Acids Res , vol.38 , pp. 117-130
    • Bolognani, F.1    Contente-Cuomo, T.2    Perrone-Bizzozero, N.I.3
  • 8
    • 78751685185 scopus 로고    scopus 로고
    • Impaired minor tri-snRNP assembly generates differential splicing defects of U12-type introns in lymphoblasts derived from a type I SMA patient
    • CrossRef Medline
    • Boulisfane N, Choleza M, Rage F, Neel H, Soret J, Bordonné R (2011) Impaired minor tri-snRNP assembly generates differential splicing defects of U12-type introns in lymphoblasts derived from a type I SMA patient. Hum Mol Genet 20:641–648. CrossRef Medline
    • (2011) Hum Mol Genet , vol.20 , pp. 641-648
    • Boulisfane, N.1    Choleza, M.2    Rage, F.3    Neel, H.4    Soret, J.5    Bordonné, R.6
  • 9
    • 0035171131 scopus 로고    scopus 로고
    • Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B’ and the Sm-like protein LSm4, and their interaction with the SMN protein
    • CrossRef Medline
    • Brahms H, Meheus L, de Brabandere V, Fischer U, Lührmann R (2001) Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B’ and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA 7:1531–1542. CrossRef Medline
    • (2001) RNA , vol.7 , pp. 1531-1542
    • Brahms, H.1    Meheus, L.2    de Brabandere, V.3    Fischer, U.4    Lührmann, R.5
  • 10
    • 84880649467 scopus 로고    scopus 로고
    • Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction
    • CrossRef Medline
    • Bronicki LM, Jasmin BJ (2013) Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction. RNA 19:1019–1037. CrossRef Medline
    • (2013) RNA , vol.19 , pp. 1019-1037
    • Bronicki, L.M.1    Jasmin, B.J.2
  • 11
    • 79952943507 scopus 로고    scopus 로고
    • Axonal regeneration and neuronal function are preserved in motor neurons lacking ss-actin in vivo
    • CrossRef Medline
    • Cheever TR, Olson EA, Ervasti JM (2011) Axonal regeneration and neuronal function are preserved in motor neurons lacking ss-actin in vivo. PLoS One 6:e17768. CrossRef Medline
    • (2011) Plos One , vol.6
    • Cheever, T.R.1    Olson, E.A.2    Ervasti, J.M.3
  • 13
    • 84857733745 scopus 로고    scopus 로고
    • SMN in spinal muscular atrophy and snRNP biogenesis
    • CrossRef Medline
    • Coady TH, Lorson CL (2011) SMN in spinal muscular atrophy and snRNP biogenesis. Wiley Interdiscip Rev RNA 2:546–564. CrossRef Medline
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 546-564
    • Coady, T.H.1    Lorson, C.L.2
  • 14
    • 0030130574 scopus 로고    scopus 로고
    • The neurobiology of childhood spinal muscular atrophy
    • CrossRef Medline
    • Crawford TO, Pardo CA (1996) The neurobiology of childhood spinal muscular atrophy. Neurobiol Dis 3:97–110. CrossRef Medline
    • (1996) Neurobiol Dis , vol.3 , pp. 97-110
    • Crawford, T.O.1    Pardo, C.A.2
  • 15
    • 33749522347 scopus 로고    scopus 로고
    • Molecular mechanisms, biological actions, and neuropharmacology of the growth-associated protein GAP-43
    • CrossRef Medline
    • Denny JB (2006) Molecular mechanisms, biological actions, and neuropharmacology of the growth-associated protein GAP-43. Curr Neuropharmacol 4:293–304. CrossRef Medline
    • (2006) Curr Neuropharmacol , vol.4 , pp. 293-304
    • Denny, J.B.1
  • 18
    • 77957973735 scopus 로고    scopus 로고
    • Skeletal muscle in motor neuron diseases: Therapeutic target and delivery route for potential treatments
    • CrossRef Medline
    • Dupuis L, Echaniz-Laguna A (2010) Skeletal muscle in motor neuron diseases: therapeutic target and delivery route for potential treatments. Curr Drug Targets 11:1250–1261. CrossRef Medline
    • (2010) Curr Drug Targets , vol.11 , pp. 1250-1261
    • Dupuis, L.1    Echaniz-Laguna, A.2
  • 19
    • 77951050303 scopus 로고    scopus 로고
    • High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function
    • CrossRef Medline
    • Fallini C, Bassell GJ, Rossoll W (2010) High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function. Mol Neurodegener 5:17. CrossRef Medline
    • (2010) Mol Neurodegener , vol.5 , pp. 17
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 20
    • 79952390939 scopus 로고    scopus 로고
    • The survival of motor neuron (SMN) protein interacts with the mRNAbinding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons
    • CrossRef Medline
    • Fallini C, Zhang H, Su Y, Silani V, Singer RH, Rossoll W, Bassell GJ (2011) The survival of motor neuron (SMN) protein interacts with the mRNAbinding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons. J Neurosci 31:3914–3925. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 3914-3925
    • Fallini, C.1    Zhang, H.2    Su, Y.3    Silani, V.4    Singer, R.H.5    Rossoll, W.6    Bassell, G.J.7
  • 21
    • 84862145991 scopus 로고    scopus 로고
    • Spinalmuscularatrophy: The role ofSMNin axonalmRNAregulation
    • CrossRef Medline
    • Fallini C, Bassell GJ, Rossoll W (2012a) Spinalmuscularatrophy: the role ofSMNin axonalmRNAregulation. Brain Res 1462:81–92. CrossRef Medline
    • (2012) Brain Res , pp. 81-92
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 22
    • 84865063851 scopus 로고    scopus 로고
    • The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
    • CrossRef Medline
    • Fallini C, Bassell GJ, Rossoll W (2012b) The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth. Hum Mol Genet 21:3703–3718. CrossRef Medline
    • (2012) Hum Mol Genet , vol.21 , pp. 3703-3718
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 23
    • 84893795463 scopus 로고    scopus 로고
    • Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons
    • CrossRef Medline
    • Fallini C, Rouanet JP, Donlin-Asp PG, Guo P, Zhang H, Singer RH, Rossoll W, Bassell GJ (2014) Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons. Dev Neurobiol 74:319–332. CrossRef Medline
    • (2014) Dev Neurobiol , vol.74 , pp. 319-332
    • Fallini, C.1    Rouanet, J.P.2    Donlin-Asp, P.G.3    Guo, P.4    Zhang, H.5    Singer, R.H.6    Rossoll, W.7    Bassell, G.J.8
  • 24
    • 0034714380 scopus 로고    scopus 로고
    • Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN)
    • CrossRef Medline
    • Friesen WJ, Dreyfuss G (2000) Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). J Biol Chem 275:26370–26375. CrossRef Medline
    • (2000) J Biol Chem , vol.275 , pp. 26370-26375
    • Friesen, W.J.1    Dreyfuss, G.2
  • 25
    • 84880659519 scopus 로고    scopus 로고
    • Atthe“junction”of spinalmuscularatrophy pathogenesis: The role of neuromuscular junction dysfunction in SMA disease progression
    • CrossRef Medline
    • Goulet BB, Kothary R, Parks RJ (2013) Atthe“junction”of spinalmuscularatrophy pathogenesis: the role of neuromuscular junction dysfunction in SMA disease progression. Curr Mol Med 13:1160–1174. CrossRef Medline
    • (2013) Curr Mol Med , vol.13 , pp. 1160-1174
    • Goulet, B.B.1    Kothary, R.2    Parks, R.J.3
  • 26
    • 79958731794 scopus 로고    scopus 로고
    • Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43
    • CrossRef Medline
    • Grasselli G, Mandolesi G, Strata P, Cesare P (2011) Impaired sprouting and axonal atrophy in cerebellar climbing fibres following in vivo silencing of the growth-associated protein GAP-43. PLoS One 6:e20791. CrossRef Medline
    • (2011) Plos One , vol.6
    • Grasselli, G.1    Mandolesi, G.2    Strata, P.3    Cesare, P.4
  • 28
    • 0031009292 scopus 로고    scopus 로고
    • Modulation of actin filament behavior by GAP-43 (Neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site
    • Medline
    • He Q, Dent EW, Meiri KF (1997) Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site. J Neurosci 17:3515–3524. Medline
    • (1997) J Neurosci , vol.17 , pp. 3515-3524
    • He, Q.1    Dent, E.W.2    Meiri, K.F.3
  • 29
    • 78651094423 scopus 로고    scopus 로고
    • HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects
    • CrossRef Medline
    • Hubers L, Valderrama-Carvajal H, Laframboise J, Timbers J, Sanchez G, Côté J (2011) HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects. Hum Mol Genet 20:553–579. CrossRef Medline
    • (2011) Hum Mol Genet , vol.20 , pp. 553-579
    • Hubers, L.1    Valderrama-Carvajal, H.2    Laframboise, J.3    Timbers, J.4    Sanchez, G.5    Côté, J.6
  • 34
    • 84904464793 scopus 로고    scopus 로고
    • SMN control of RNP assembly: From post-transcriptional gene regulation to motor neuron disease
    • CrossRef Medline
    • Li DK, Tisdale S, Lotti F, Pellizzoni L (2014) SMN control of RNP assembly: From post-transcriptional gene regulation to motor neuron disease. Semin Cell Dev Biol 32:22–29. CrossRef Medline
    • (2014) Semin Cell Dev Biol , vol.32 , pp. 22-29
    • Li, D.K.1    Tisdale, S.2    Lotti, F.3    Pellizzoni, L.4
  • 35
    • 78649723966 scopus 로고    scopus 로고
    • Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy
    • CrossRef Medline
    • Ling KK, Lin MY, Zingg B, Feng Z, Ko CP (2010) Synaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophy. PLoS One 5:e15457. CrossRef Medline
    • (2010) Plos One , vol.5
    • Ling, K.K.1    Lin, M.Y.2    Zingg, B.3    Feng, Z.4    Ko, C.P.5
  • 36
    • 83455213467 scopus 로고    scopus 로고
    • Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
    • CrossRef Medline
    • Ling KK, Gibbs RM, Feng Z, Ko CP (2012) Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy. Hum Mol Genet 21:185–195. CrossRef Medline
    • (2012) Hum Mol Genet , vol.21 , pp. 185-195
    • Ling, K.K.1    Gibbs, R.M.2    Feng, Z.3    Ko, C.P.4
  • 39
    • 0042887389 scopus 로고    scopus 로고
    • Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding
    • CrossRef Medline
    • McWhorter ML, Monani UR, Burghes AH, Beattie CE (2003) Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. J Cell Biol 162:919–931. CrossRef Medline
    • (2003) J Cell Biol , vol.162 , pp. 919-931
    • McWhorter, M.L.1    Monani, U.R.2    Burghes, A.H.3    Beattie, C.E.4
  • 41
    • 41149113045 scopus 로고    scopus 로고
    • Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
    • Medline
    • Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH (2008) Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy. Hum Mol Genet 17:949–962. Medline
    • (2008) Hum Mol Genet , vol.17 , pp. 949-962
    • Murray, L.M.1    Comley, L.H.2    Thomson, D.3    Parkinson, N.4    Talbot, K.5    Gillingwater, T.H.6
  • 42
    • 34047148903 scopus 로고    scopus 로고
    • Chaperoning ribonucleoprotein biogenesis in health and disease
    • CrossRef Medline
    • Pellizzoni L (2007) Chaperoning ribonucleoprotein biogenesis in health and disease. EMBO Rep 8:340–345. CrossRef Medline
    • (2007) EMBO Rep , vol.8 , pp. 340-345
    • Pellizzoni, L.1
  • 43
    • 84888400801 scopus 로고    scopus 로고
    • Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization
    • CrossRef Medline
    • Rage F, Boulisfane N, Rihan K, Neel H, Gostan T, Bertrand E, Bordonné R, Soret J (2013) Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization. RNA 19:1755–1766. CrossRef Medline
    • (2013) RNA , vol.19 , pp. 1755-1766
    • Rage, F.1    Boulisfane, N.2    Rihan, K.3    Neel, H.4    Gostan, T.5    Bertrand, E.6    Bordonné, R.7    Soret, J.8
  • 44
    • 70249095607 scopus 로고    scopus 로고
    • Spinal muscular atrophy and a model for survival of motor neuron protein function in axonal ribonucleoprotein complexes
    • Medline
    • Rossoll W, Bassell GJ (2009) Spinal muscular atrophy and a model for survival of motor neuron protein function in axonal ribonucleoprotein complexes. Results Probl Cell Differ 48:289–326. Medline
    • (2009) Results Probl Cell Differ , vol.48 , pp. 289-326
    • Rossoll, W.1    Bassell, G.J.2
  • 45
    • 0036154096 scopus 로고    scopus 로고
    • Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: A role for Smn in RNA processing in motor axons?
    • CrossRef Medline
    • Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M (2002) Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet 11:93–105. CrossRef Medline
    • (2002) Hum Mol Genet , vol.11 , pp. 93-105
    • Rossoll, W.1    Ak, K.2    Ohndorf, U.M.3    Steegborn, C.4    Jablonka, S.5    Sendtner, M.6
  • 46
    • 0345599021 scopus 로고    scopus 로고
    • Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons
    • CrossRef Medline
    • Rossoll W, Jablonka S, Andreassi C, Kröning AK, Karle K, Monani UR, Sendtner M (2003) Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons. J Cell Biol 163:801–812. CrossRef Medline
    • (2003) J Cell Biol , vol.163 , pp. 801-812
    • Rossoll, W.1    Jablonka, S.2    Reassi, C.3    Kröning, A.K.4    Karle, K.5    Monani, U.R.6    Sendtner, M.7
  • 47
    • 84890188869 scopus 로고    scopus 로고
    • Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy
    • CrossRef Medline
    • Ruiz R, Tabares L (2014) Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy. J Anat 224:74–84. CrossRef Medline
    • (2014) J Anat , vol.224 , pp. 74-84
    • Ruiz, R.1    Tabares, L.2
  • 48
    • 84908122721 scopus 로고    scopus 로고
    • Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation
    • CrossRef Medline
    • Saal L, Briese M, Kneitz S, Glinka M, Sendtner M (2014) Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation. RNA 20:1789–1802. CrossRef Medline
    • (2014) RNA , vol.20 , pp. 1789-1802
    • Saal, L.1    Briese, M.2    Kneitz, S.3    Glinka, M.4    Sendtner, M.5
  • 50
    • 84870562303 scopus 로고    scopus 로고
    • GAP-43 dependency defines distinct effects of netrin-1 on cortical and spinal neurite outgrowth and directional guidance
    • CrossRef Medline
    • Shen Y, Meiri K (2013) GAP-43 dependency defines distinct effects of netrin-1 on cortical and spinal neurite outgrowth and directional guidance. Int J Dev Neurosci 31:11–20. CrossRef Medline
    • (2013) Int J Dev Neurosci , vol.31 , pp. 11-20
    • Shen, Y.1    Meiri, K.2
  • 51
    • 0036138058 scopus 로고    scopus 로고
    • Growthassociated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system
    • Medline
    • Shen Y, Mani S, Donovan SL, Schwob JE, Meiri KF (2002) Growthassociated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J Neurosci 22:239–247. Medline
    • (2002) J Neurosci , vol.22 , pp. 239-247
    • Shen, Y.1    Mani, S.2    Donovan, S.L.3    Schwob, J.E.4    Meiri, K.F.5
  • 53
    • 0028853240 scopus 로고
    • Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43
    • CrossRef Medline
    • Strittmatter SM, Fankhauser C, Huang PL, Mashimo H, Fishman MC (1995) Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell 80:445–452. CrossRef Medline
    • (1995) Cell , vol.80 , pp. 445-452
    • Strittmatter, S.M.1    Fankhauser, C.2    Huang, P.L.3    Mashimo, H.4    Fishman, M.C.5
  • 54
    • 84890146437 scopus 로고    scopus 로고
    • SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3′-end formation of histone mRNAs
    • CrossRef Medline
    • Tisdale S, Lotti F, Saieva L, Van Meerbeke JP, Crawford TO, Sumner CJ, Mentis GZ, Pellizzoni L (2013) SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3′-end formation of histone mRNAs. Cell Rep 5:1187–1195. CrossRef Medline
    • (2013) Cell Rep , vol.5 , pp. 1187-1195
    • Tisdale, S.1    Lotti, F.2    Saieva, L.3    Van Meerbeke, J.P.4    Crawford, T.O.5    Sumner, C.J.6    Mentis, G.Z.7    Pellizzoni, L.8
  • 55
    • 84881225582 scopus 로고    scopus 로고
    • Metabolic labeling with noncanonical amino acids and visualization by chemoselective fluorescent tagging
    • Chapter 7:Unit7.11. CrossRef Medline
    • Tom Dieck S, Muller A, Nehring A, Hinz FI, Bartnik I, Schuman EM, Dieterich DC (2012) Metabolic labeling with noncanonical amino acids and visualization by chemoselective fluorescent tagging. Curr Protoc Cell Biol Chapter 7:Unit7.11. CrossRef Medline
    • (2012) Curr Protoc Cell Biol
    • Tom Dieck, S.1    Muller, A.2    Nehring, A.3    Hinz, F.I.4    Bartnik, I.5    Schuman, E.M.6    Dieterich, D.C.7
  • 56
    • 25844461744 scopus 로고    scopus 로고
    • Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy
    • CrossRef Medline
    • Winkler C, Eggert C, Gradl D, Meister G, Giegerich M, Wedlich D, Laggerbauer B, Fischer U (2005) Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy. Genes Dev 19:2320–2330. CrossRef Medline
    • (2005) Genes Dev , vol.19 , pp. 2320-2330
    • Winkler, C.1    Eggert, C.2    Gradl, D.3    Meister, G.4    Giegerich, M.5    Wedlich, D.6    Laggerbauer, B.7    Fischer, U.8
  • 57
    • 84862139693 scopus 로고    scopus 로고
    • Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy
    • CrossRef Medline
    • Workman E, Kolb SJ, Battle DJ (2012) Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy. Brain Res 1462:93–99. CrossRef Medline
    • (2012) Brain Res , vol.1462 , pp. 93-99
    • Workman, E.1    Kolb, S.J.2    Battle, D.J.3
  • 58
    • 76549115901 scopus 로고    scopus 로고
    • Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy
    • CrossRef Medline
    • Ymlahi-Ouazzani Q, J Bronchain O, Paillard E, Ballagny C, Chesneau A, Jadaud A, Mazabraud A, Pollet N (2010) Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy. Neurogenetics 11:27–40. CrossRef Medline
    • (2010) Neurogenetics , vol.11 , pp. 27-40
    • Ymlahi-Ouazzani, Q.1    J Bronchain, O.2    Paillard, E.3    Ballagny, C.4    Chesneau, A.5    Jadaud, A.6    Mazabraud, A.7    Pollet, N.8
  • 60
    • 43049168361 scopus 로고    scopus 로고
    • SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing
    • CrossRef Medline
    • Zhang Z, Lotti F, Dittmar K, Younis I, Wan L, Kasim M, Dreyfuss G (2008) SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell 133:585–600. CrossRef Medline
    • (2008) Cell , vol.133 , pp. 585-600
    • Zhang, Z.1    Lotti, F.2    Dittmar, K.3    Younis, I.4    Wan, L.5    Kasim, M.6    Dreyfuss, G.7
  • 61
    • 84896304665 scopus 로고    scopus 로고
    • Neuritin, a neurotrophic factor in nervous system physiology
    • CrossRef Medline
    • Zhou S, Zhou J (2014) Neuritin, a neurotrophic factor in nervous system physiology. Curr Med Chem 21:1212–1219. CrossRef Medline
    • (2014) Curr Med Chem , vol.21 , pp. 1212-1219
    • Zhou, S.1    Zhou, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.