Mechanism of thermal decomposition of carbamoyl phosphate and its stabilization by aspartate and ornithine transcarbamoylases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 44, 2008, Pages 16918-16923

  Wang, Qin ^a   Xia, Jiarong ^a   Guallar, Victor ^b   Krilov, Goran ^a   Kantrowitz, Evan R ^a  

^a BOSTON COLLEGE   (United States)

^b BARCELONA SUPERCOMPUTING CENTER   (Spain)

Author keywords

Carbamoyltransferase; Quantum mechanics molecular mechanics; Substrate stabilization; Thermophile

Indexed keywords

ASPARTIC ACID; CARBAMOYL PHOSPHATE; ORNITHINE CARBAMOYLTRANSFERASE;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CONFORMATION; DECOMPOSITION; ENZYME ACTIVE SITE; ENZYME BINDING; ESCHERICHIA COLI; GEOMETRY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; PROTON TRANSPORT; QUANTUM MECHANICS; THERMAL ANALYSIS; THERMOPHILE; THERMOSTABILITY;

EID: 84961985801     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0809631105     Document Type: Article

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