BRAF and MAP2K1 mutations in Langerhans cell histiocytosis: A study of 50 cases

Human Pathology

Volumn 52, Issue , 2016, Pages 61-67

  Alayed, Khaled ^a,b   Medeiros, L Jeffrey ^a   Patel, Keyur P ^a   Zuo, Zhuang ^a   Li, Shaoying ^a   Verma, Shalini ^a   Galbincea, John ^a   Cason, R Craig ^a   Luthra, Rajyalakshmi ^a   Yin, C Cameron ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Age; BRAF mutation; Immunohistochemistry; Langerhans cell histiocytosis; MAP2K1 mutation; Pyrosequencing

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BONE; BRAF GENE; CHILD; CLINICAL ARTICLE; COLON; CONTROLLED STUDY; DURA MATER; FEMALE; GENE; GENE FREQUENCY; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGERHANS CELL HISTIOCYTOSIS; LUNG; MALE; MAP2K1 GENE; SKIN; WILD TYPE; BIOPSY; DNA MUTATIONAL ANALYSIS; ENZYMOLOGY; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; INFANT; MIDDLE AGED; MUTATION; PATHOLOGY; PHENOTYPE; PRESCHOOL CHILD; YOUNG ADULT;

B RAF KINASE; BRAF PROTEIN, HUMAN; GENETIC MARKER; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1;

ADOLESCENT; ADULT; AGED; BIOPSY; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MAP KINASE KINASE 1; MIDDLE AGED; MUTATION; PHENOTYPE; PROTO-ONCOGENE PROTEINS B-RAF; YOUNG ADULT;

EID: 84961837668     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2015.12.029     Document Type: Article

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