B-RAF mutant alleles associated with langerhans cell histiocytosis, a granulomatous pediatric disease

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Satoh, Takeshi ^a   Smith, Alexander ^b   Sarde, Aurelien ^a   Lu, Hui chun ^b   Mian, Sophie ^b   Trouillet, Celine ^a   Mufti, Ghulam ^b   Emile, Jean Francois ^c   Fraternali, Franca ^b   Donadieu, Jean ^d   Geissmann, Frederic ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c HÔPITAL AMBROISE PARÉ   (France)

^d ARMAND TROUSSEAU HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; BRAF PROTEIN, HUMAN; RAF PROTEIN;

ADOLESCENT; ADULT; ALLELE; ARTICLE; B RAF GENE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME POLYMORPHISM; ENZYME STRUCTURE; FEMALE; GENE; GENE FUNCTION; GENE INSERTION; GENE STRUCTURE; GENETIC ASSOCIATION; GRANULOMA; HISTIOCYTOSIS X; HUMAN; HUMAN CELL; INFANT; MALE; MONOCYTE; MUTANT; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PYROSEQUENCING; SCHOOL CHILD; T LYMPHOCYTE; AMINO ACID SEQUENCE; CELL STRAIN HEK293; ENZYMOLOGY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; LANGERHANS CELL HISTIOCYTOSIS; LYMPHOCYTE; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION;

ALLELES; AMINO ACID SEQUENCE; CHILD; CHILD, PRESCHOOL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GRANULOMA; HEK293 CELLS; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; INFANT; LYMPHOCYTES; MALE; MOLECULAR SEQUENCE DATA; MONOCYTES; MUTATION; PHOSPHORYLATION; POLYMORPHISM, GENETIC; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTIONAL ACTIVATION; YOUNG ADULT;

EID: 84859593606     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033891     Document Type: Article

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