Longitudinal changes in functional brain connectivity predicts conversion to Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 51, Issue 2, 2016, Pages 377-389

  Serra, Laura ^a   Cercignani, Mara ^a,b   Mastropasqua, Chiara ^a   Torso, Mario ^a   Spanò, Barbara ^a   Makovac, Elena ^a   Viola, Vanda ^a   Giulietti, Giovanni ^a   Marra, Camillo ^c   Caltagirone, Carlo ^a,d   Bozzali, Marco ^a  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c CATHOLIC UNIVERSITY   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Alzheimer's disease; functional disconnection; grey matter atrophy; longitudinal study; mild cognitive impairment

Indexed keywords

BIOLOGICAL MARKER;

AGED; ALZHEIMER DISEASE; ANALOG DIGITAL CONVERTER; ARTICLE; BRAIN; BRAIN ATROPHY; CLINICAL ARTICLE; CONNECTOME; CONTROLLED STUDY; DEFAULT MODE NETWORK; DIAGNOSTIC ACCURACY; FEMALE; FOLLOW UP; GRAY MATTER; HUMAN; LONGITUDINAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PRECUNEUS; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; ATROPHY; BRAIN MAPPING; COGNITIVE DEFECT; CROSS-SECTIONAL STUDY; DIAGNOSTIC IMAGING; DISCRIMINANT ANALYSIS; DISEASE COURSE; IMAGE PROCESSING; NERVE TRACT; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; REST;

AGED; ALZHEIMER DISEASE; ATROPHY; BRAIN; BRAIN MAPPING; COGNITIVE DYSFUNCTION; CROSS-SECTIONAL STUDIES; DISCRIMINANT ANALYSIS; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GRAY MATTER; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; PROGNOSIS; REST;

EID: 84961832128     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150961     Document Type: Article

References (59)

1. Petersen RC, Caracciolo B, Brayne C, Gauthier S, Jelic V, Fratiglioni L. (2014). Mild cognitive impairment: A concept in evolution. J Intern Med 275, 214-228.
2. Karch CM, Cruchaga C, Goate AM. (2014). Alzheimer's disease genetics: From the bench to the clinic. Neuron 83, 11-26.
3. Serra L, Cercignani M, Petrosini L, Basile B, Perri R, Fadda L, SpanòB, Marra C, Giubilei F, Carlesimo GA, Caltagirone C, Bozzali M. (2011). Neuroanatomical correlates of cognitive reserve in Alzheimer disease. Rejuvenation Res 14, 143-151.
4. Bozzali M, Dowling C, Serra L, SpanòB, Torso M, Marra C, Castelli D, Dowell NG, Koch G, Caltagirone C, Cercignani M. (2014). The impact of cognitive reserve on brain functional connectivity in Alzheimer's disease. J Alzheimers Dis 44, 243-250.
5. Serra L, Musicco M, Cercignani M, Torso M, Spanò B, Mastropasqua C, Giulietti G, Marra C, Bruno G, Koch G, Caltagirone C, Bozzali M. (2015). Cognitive reserve and the risk for Alzheimer's disease: A longitudinal study. Neurobiol Aging 36, 592-600.
6. Serra L, Giulietti G, Cercignani M, Spanò B, Torso M, Castelli D, Perri R, Fadda L, Marra C, Caltagirone C, BozzaliM(2013). Mild cognitive impairment: Same identity for different entities. J Alzheimers Dis 33, 1157-1165.
7. Killiany RJ, Gomez-Isla T, Moss M, Kikinis R, Sandor T, Jolesz F, Tanzi R, Jones K, Hyman BT, Albert MS. (2000). Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease. Ann Neurol 47, 430-439.
8. BozzaliM, FilippiM, Magnani G, CercignaniM, Franceschi M, Schiatti E, Castiglioni S, Mossini R, Falautano M, Scotti G, Comi G, Falini A. (2006). The contribution of voxelbased morphometry in staging patients with mild cognitive impairment. Neurology 67, 453-460.
9. Jack CR Jr, Weigand SD, Shiung MM, Przybelski SA, O'Brien PC, Gunter JL, Knopman DS, Boeve BF, Smith GE, Petersen RC. (2008). Atrophy rates accelerate in amnestic mild cognitive impairment. Neurology 70, 1740-1752.
10. Whitwell JL, Shiung MM, Przybelski SA, Weigand SD, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. (2008). MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment. Neurology 70, 512-520.
11. Ashburner J, Friston KJ. (2001)Whyvoxel-based morphometry should be used. Neuroimage 14, 1238-1243.
12. Ashburner J, Friston KJ. (2005). Unified segmentation. Neuroimage 26, 839-851.
13. Risacher SL, Saykin AJ, West JD, Shen L, Firpi HA, McDonald BC, Alzheimer's Disease Neuroimaging Initiative. (ADNI). (2009). Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort. Curr Alzheimer Res 6, 347-361.
14. Risacher SL, Shen L, West JD, Kim S, McDonald BC, Beckett LA, Harvey DJ, Jack CR Jr, Weiner MW, Saykin AJ, Alzheimer's Disease Neuroimaging Initiative. (ADNI). (2010). Longitudinal MRI atrophy biomarkers: Relationship to conversion in the ADNI cohort. Neurobiol Aging 31, 1401-1418.
15. Bozzali M, Padovani A, Caltagirone C, Borroni B. (2011). Regional grey matter loss and brain disconnection across Alzheimer disease evolution. Curr Med Chem 18, 2452-2458.
16. Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE. (2009). Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci U S A 106, 7209-7214.
17. Zhou J, Greicius MD, Gennatas ED, Growdon ME, Jang JY, Rabinovici GD, Kramer JH, Weiner M, Miller BL, Seeley WW. (2010). Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain 133, 1352-1367.
18. Premi E, Formenti A, Gazzina S, Archetti S, Gasparotti R, Padovani A, Borroni B. (2014). Effect of TMEM106B polymorphism on functional network connectivity in asymptomatic GRN mutation carriers. JAMA Neurol 71, 216-221.
19. Greicius MD, Supekar K, Menon V, Dougherty RF. (2009). Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 19, 72-78.
20. FoxMD, GreiciusM(2010). Clinical applications of resting state functional connectivity. Front Syst Neurosci 4, 19.
21. Qi Z, Wu X, Wang Z, Zhang N, Dong H, Yao L, Li K. (2010). Impairment and compensation coexist in amnestic MCI default mode network. Neuroimage 50, 48-55.
22. Gili T, Cercignani M, Serra L, Perri R, Giove F, Maraviglia B, Caltagirone C, BozzaliM(2011). Regional brain atrophy and functional disconnection across Alzheimer's disease evolution. J Neurol Neurosurg Psychiatry 82, 58-66.
23. Stern Y. (2012). Cognitive reserve in ageing and Alzheimer's disease. Lancet Neurol 11, 1006-1012.
24. Misra C, Fan Y, Davatzikos C. (2009). Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: Results from ADNI. Neuroimage 44, 1415-1422.
25. Runtti H, Mattila J, Van Gils M, Koikkalainen J, Soininen H, Lötjönen J, Alzheimer's Disease Neuroimaging Initiative. (2014). Quantitative evaluation of disease progression in a longitudinal mild cognitive impairment cohort. J Alzheimers Dis 39, 49-61.
26. Wang Z, Liang P, Jia X, Jin G, Song H, Han Y, Lu J, Li K. (2012). The baseline and longitudinal changes of PCC connectivity in mild cognitive impairment: A combined structure and resting-state fMRI study. PLoS One 7, e36838.
27. Wang Z, Liang P, Jia X, Qi Z, Yu L, YangY, ZhouW, Lu J, Li K(2011). Baseline and longitudinal patterns of hippocampal connectivity in mild cognitive impairment: Evidence from resting state fMRI. J Neurol Sci 309, 79-85.
28. Yao H, Zhou B, Zhang Z, Wang P, Guo Y, Shang Y, Wang L, Zhang X, An N, Liu Y, Alzheimer's Disease Neuroimaging Initiative. (2014). Longitudinal alteration of amygdalar functional connectivity in mild cognitive impairment subjects revealed by resting-state FMRI. Brain Connect 4, 361-370.
29. American Psychiatric Association. (2013). DSM-V Diagnostic and Statistical Manual of Mental Disorders. Edizione Italiana: Masson, Milano
30. FolsteinMF, Folstein SE, McHugh PR. (1975). "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
31. Magni E, Binetti G, Padovani A, Cappa SF, Bianchetti A, Trabucchi M. (1996). The Mini-Mental State Examination in Alzheimer's disease and multi-infarct dementia. Int Psychogeriatr 8, 127-134.
32. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. (1982). A new clinical scale for the staging of dementia. Br J Psychiatry 140, 566-572.
33. Scheltens P, Launer LJ, Barkhof F, Weinstein HC, Van Gool WA. (1995). Visual assessment of medial temporal lobe atrophy on magnetic resonance imaging: Interobserver reliability. J Neurol 242, 557-560.
34. Hachinski VC, Iliff LD, Zilhka E, Du Boulay GH, McAllister VL, Marshall J, Russell RW, Symon L. (1975). Cerebral blood flow in dementia. Arch Neurol 32, 632-637.
35. Serra L, Cercignani M, Lenzi D, Perri R, Fadda L, Caltagirone C, Macaluso E, Bozzali M. (2010). Grey and white matter changes at different stages of Alzheimer's disease. J Alzheimers Dis 19, 147-159.
36. Serra L, Perri R, Cercignani M, Spanò B, Fadda L, Marra C, Carlesimo GA, Caltagirone C, Bozzali M. (2010). Are the behavioral symptoms of Alzheimer's disease directly associated with neurodegeneration'. J Alzheimers Dis 21, 627-639.
37. Büsch D, Hagemann N, Bender N. (2010). The dimensionality of the Edinburgh Handedness Inventory: An analysis with models of the item response theory. Laterality 15, 610-628.
38. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH. (2011). The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269.
39. Carlesimo GA, Caltagirone C, Gainotti G. (1996). The Mental Deterioration Battery: Normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The Group for the Standardization of the Mental Deterioration Battery. Eur Neurol 36, 378-384.
40. Carlesimo GA, Buccione I, Fadda L, Graceffa A, Mauri M, Lo Russo S, Bevilacqua G, Caltagirone C. (2002). Stan dardizzazione di due test di memoria per uso clinico: Breve Racconto e Figura di Rey. Nuova Riv Neurol 12, 1-13.
41. Monaco M, Costa A, Caltagirone C, Carlesimo GA. (2013). Forward and backward span for verbal and visuo-spatial data: Standardization and normative data from an Italian adult population. Neurol Sci 34, 749-754.
42. Nocentini U, Di Vincenzo S, Panella M, Pasqualetti P, Caltagirone C. (2002). La valutazione delle funzioni esecutive nella pratica neuropsicologica: Dal Modified Card Sorting Test al Modified Card Sorting Test-Roma Version. Dati di standardizzazione. Nuova Riv Neurol 12, 14-24.
43. Miceli G, Laudanna A, Burani C, CapassoR(1991). Batteria per l'analisi dei deficit afasici. Ass.ne per lo sviluppo delle ricerche neuropsicologiche, Berdata, Milano
44. Kelley K, Maxwell SE. (2003). Sample size for multiple regression: Obtaining regression coefficient that are accurate, not simply significant. Psychol Methods 8, 305-321.
45. Barnes J, Bartlett JW, Van De Pol LA, Loy CT, Scahill RI, Frost C, Thompson P, Fox NC. (2009). A meta-Analysis of hippocampal atrophy rates in Alzheimer's disease. Neurobiol Aging 30, 1711-1723.
46. Bernard C, Helmer C, Dilharreguy B, Amieva H, Auriacombe S, Dartigues JF, Allard M, Catheline G. (2014). Time course of brain volume changes in the preclinical phase of Alzheimer's disease. Alzheimers Dement 10, 143-151.
47. Carr DB, Barco PP, Wallendorf MJ, Snellgrove CA, Ott BR. (2011). Predicting road test performance in drivers with dementia. J Am Geriatr Soc 59, 2112-2117.
48. Cassaday HJ, Nelson AJ, Pezze M.A. (2014). From attention to memory along the dorsal-ventral axis of the medial prefrontal cortex: Some methodological considerations. Front Syst Neurosci 8, 160.
49. Matsuda H, Kitayama N, Ohnishi T, Asada T, Nakano S, Sakamoto S, Imabayashi E, Katoh A. (2002). Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease. J Nucl Med 43, 304e11.
50. Borroni B, Anchisi D, Paghera B, Vicini B, Kerrouche N, Garibotto V, Terzi A, Vignolo LA, Di Luca M, Giubbini R, Padovani A, Perani D. (2006). Combined 99mTc-ECD SPECT and neuropsychological studies in MCI for the assessment of conversion to AD. Neurobiol Aging 27, 24-31.
51. Chételat G, Desgranges B, Landeau B, Mézenge F, Poline JB, De la Sayette V, Viader F, Eustache F, Baron JC. (2008). Direct voxel-based comparison between grey matter hypometabolism and atrophy in Alzheimer's disease. Brain 131, 60-71.
52. Diaz-de-Grenu LZ, Acosta-Cabronero J, Chong YF, Pereira JM, Sajjadi SA, Williams GB, Nestor PJ. (2014). A brief history of voxel-based grey matter analysis in Alzheimer's disease. J Alzheimers Dis 38, 647-659.
53. Damoiseaux JS, Prater KE, Miller BL, Greicius MD. (2012). Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging 33, 828.e19-30.
54. Serra L, Fadda L, Perri R, Spanò B, Marra C, Castelli D, Torso M, Makovac E, Cercignani M, Caltagirone C, Bozzali M. (2014). Constructional apraxia as a distinctive cognitive and structural brain feature of pre-senile Alzheimer's disease. J Alzheimers Dis 38, 391-402.
55. Barbeau EJ, Didic M, Joubert S, Guedj E, Koric L, Felician O, Ranjeva JP, Cozzone P, Ceccaldi M. (2012). Extent and neural basis of semantic memory impairment in mild cognitive impairment. J Alzheimers Dis 28, 823-837.
56. Bernal B, Ardila A, RosselliM(2015). Broca's area network in language function: A pooling-data connectivity study. Front Psychol 6, 687.
57. Ben-Zvi S, Soroker N, Levy DA. (2015). Parietal lesion effects on cued recall following pair associate learning. Neuropsychologia 73, 176-194.
58. Lundstrom BN, Ingvar M, Petersson KM. (2005). The role of precuneus and left inferior frontal cortex during source memory episodic retrieval. Neuroimage 27, 824-834.
59. Lundstrom BN, Petersson KM, Andersson J, Johansson M, Fransson P, IngvarM(2003). Isolating the retrieval of imagined pictures during episodic memory: Activation of the left precuneus and left prefrontal cortex. Neuroimage 20, 1934-1943.