Long-Term Morphological and Microarchitectural Stability of Tissue-Engineered, Patient-Specific Auricles in Vivo

Tissue Engineering - Part A

Volumn 22, Issue 5-6, 2016, Pages 461-468

  Cohen, Benjamin Peter ^a   Hooper, Rachel C ^b   Puetzer, Jennifer L ^a   Nordberg, Rachel ^a   Asanbe, Ope ^b   Hernandez, Karina A ^b   Spector, Jason A ^a,b   Bonassar, Lawrence J ^a  

^a Cornell University   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; BIOMECHANICS; BODY FLUIDS; CARTILAGE; COLLAGEN; COMPUTER AIDED DESIGN; HYDROXYPROLINE; INJECTION MOLDING; MECHANICAL PERMEABILITY; SCAFFOLDS (BIOLOGY); TISSUE ENGINEERING;

AURICULAR CHONDROCYTES; COMPUTER ASSISTED DESIGNS; DIGITAL PHOTOGRAMMETRY; HYDRAULIC PERMEABILITY; HYDROXYPROLINE CONTENT; LONG TERM STABILITY; MANUFACTURING TECHNOLOGIES; TISSUE STABILITIES;

TISSUE;

COLLAGEN; DNA; ELASTIN; GLYCOSAMINOGLYCAN; HYDROXYPROLINE; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BOVINE; CARTILAGE CELL; DNA CONTENT; EAR CARTILAGE; ENCAPSULATION; HISTOLOGY; HUMAN; HUMAN TISSUE; HYDRAULIC PERMEABILITY; HYDROGEL; IN VIVO STUDY; MALE; MECHANICS; NONHUMAN; PERICHONDRIUM; PRIORITY JOURNAL; RAT; TISSUE ENGINEERING; TISSUE NECROSIS; TISSUE SCAFFOLD; TISSUE STRUCTURE; YOUNG MODULUS; ANATOMY AND HISTOLOGY; ANIMAL; BIOMECHANICS; CELL SHAPE; CHEMISTRY; NUDE RAT; PHYSIOLOGY; PROCEDURES; PROSTHESIS IMPLANTATION;

ANIMALS; BIOMECHANICAL PHENOMENA; CATTLE; CELL SHAPE; EAR CARTILAGE; HUMANS; MALE; PROSTHESIS IMPLANTATION; RATS, NUDE; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84961795103     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2015.0323     Document Type: Article

References (43)

1. Luquetti, D.V., Heike, C.L., Hing, A. V, Cunningham, M.L., and Cox, T.C. Microtia: epidemiology and genetics. Am J Med Genet A 158A, 124, 2012.
2. Fernandes, R. Ear Reconstruction. Local and Regional Flaps Head Neck Reconstruction: A Practical Approach. First. Hoboken, NJ: John Wiley & Sons, Inc., 2015, pp. 170-185.
3. Shieh, S., Terada, S., and Vacanti, J.P. Tissue engineering auricular reconstruction: in vitro and in vivo studies. Biomaterials 25, 1545, 2004.
4. Bichara, D.A., O'Sullivan, N.-A., Pomerantseva, I., Zhao, X., Sundback, C.A., Vacanti, J.P., and Randolph, M.A. The tissue-engineered auricle: past, present, and future. Tissue Eng Part B Rev 18, 51, 2012.
5. Angela, R., Cao, Y.L., Clemente, I., Pap, S., Vacanti, M., Eavey, R.D., and Vacanti, C.A. Characteristics of cartilage engineered from human pediatric auricular cartilage. Plast Reconstr Surg 103, 1111, 1999.
6. Britt, J.C., and Park, S.S. Autogenous tissue-engineered cartilage. Arch Otolaryngol Head Neck Surg 124, 671, 1998.
7. Brent, B. Microtia repair with rib cartilage grafts. A review of personal experience with 1000 cases. Clin Plast Surg 29, 257, 2002.
8. Romo, T., and Reitzen, S.D. Aesthetic microtia reconstruction with Medpor. Facial Plast Surg 24, 120, 2008.
9. Cao, Y., Vacanti, J.P., Paige, K.T., Upton, J., and Vacanti, C.A. Transplantation of chondrocytes utilizing a polymercell construct to produce tissue-engineered cartilage in the shape of a human ear. Plast Reconstr Surg 100, 297, 1997.
10. Kamil, S.H., Vacanti, M.P., Aminuddin, B.S., Jackson, M.J., Vacanti, C.A., and Eavey, R.D. Tissue engineering of a human sized and shaped auricle using a mold. Laryngoscope 114, 867, 2004.
11. Zhang, L., He, A., Yin, Z., Yu, Z., Luo, X., Liu, W., Zhang, W., Cao, Y., Liu, Y., and Zhou, G. Biomaterials regeneration of human-ear-shaped cartilage by co-culturing human microtia chondrocytes with BMSCs. Biomaterials 35, 4878, 2014.
12. Isogai, N., Asamura, S., Higashi, T., Ikada, Y., Morita, S., Hillyer, J., Jacquet, R., and Landis, W.J. Tissue engineering of an auricular cartilage model utilizing cultured chondrocyte-poly(L-lactide-e-caprolactone) scaffolds. Tissue Eng 10, 673, 2004.
13. Chang, S.C.N., Rowley, J.A., Tobias, G., Genes, N.G., Roy, A.K., Mooney, D.J., Vacanti, C.A., and Bonassar, L.J. Injection molding of chondrocyte/alginate constructs in the shape of facial implants. J Biomed Mater Res 55, 503, 2001.
14. Xu, J.-W., Zaporojan, V., Peretti, G.M., Roses, R.E., Morse, K.R., Roy, A.K., Mesa, J.M., Randolph, M.A., Bonassar, L.J., and Yaremchuk, M.J. Injectable tissueengineered cartilage with different chondrocyte sources. Plast Reconstr Surg 113, 1361, 2004.
15. Awad, H.A., Wickham, M.Q., Leddy, H.A., Gimble, J.M., and Guilak, F. Chondrogenic differentiation of adiposederived adult stem cells in agarose, alginate, and gelatin scaffolds. Biomaterials 25, 3211, 2004.
16. Cao, Y., Angela, R., Vacanti, M., Ibarra, C., Arevalo, C., and Vacanti, C.A. Comparative study of the use of poly(-glycolic acid), calcium alginate and pluronics in the engineering of autologous porcine cartilage. J Biomater Sci Polym Ed 9, 475, 1998.
17. Isogai, N., Kusuhara, H., Ikada, Y., Ohtani, H., Jacquet, R., Hillyer, J., Lowder, E., and Landis, W.J. Comparison of different chondrocytes for use in tissue engineering of cartilage model structures. Tissue Eng 12, 691, 2006.
18. Pelttari, K., Winter, A., Steck, E., Goetzke, K., Hennig, T., Ochs, B.G., Aigner, T., and Richter, W. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 54, 3254, 2006.
19. Liu, Y., Zhang, L., Zhou, G., Li, Q., Liu, W., Yu, Z., Luo, X., Jiang, T., Zhang, W., and Cao, Y. In vitro engineering of human ear-shaped cartilage assisted with CAD/CAM technology. Biomaterials 31, 2176, 2010.
20. Sterodimas, A., and de Faria, J. Human auricular tissue engineering in an immunocompetent animal model. Aesthet Surg J 33, 283, 2013.
21. Lee, S.J., Broda, C., Atala, A., and Yoo, J.J. Engineered cartilage covered ear implants for auricular cartilage reconstruction. Biomacromolecules 12, 306, 2011.
22. Zhou, L., Pomerantseva, I., Bassett, E.K., Bowley, C.M., Zhao, X., Bichara, D.A., Kulig, K.M., Vacanti, J.P., Randolph, M.A., and Sundback, C.A. Engineering ear constructs with a composite scaffold to maintain dimensions. Tissue Eng Part A 17, 1573, 2011.
23. Liao, H.T., Zheng, R., Liu, W., Zhang, W.J., Cao, Y., and Zhou, G. Prefabricated, ear-shaped cartilage tissue engineering by scaffold-free porcine chondrocyte membrane. Plast Reconstr Surg 135, 313, 2015.
24. Xue, J., Feng, B., Zheng, R., Lu, Y., Zhou, G., Liu, W., Cao, Y., Zhang, Y., and Zhang, W.J. Engineering earshaped cartilage using electrospun fibrous membranes of gelatin/polycaprolactone. Biomaterials 34, 2624, 2013.
25. Reiffel, A.J., Kafka, C., Hernandez, K.A., Popa, S., Perez, J.L., Zhou, S., Pramanik, S., Brown, B.N., Ryu, W.S., Bonassar, L.J., and Spector, J.A. High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities. PLoS One 8, e56506, 2013.
26. Von Bomhard, A., Veit, J., Bermueller, C., Rotter, N., Staudenmaier, R., Storck, K., and The, H.N. Prefabrication of 3D cartilage contructs: towards a tissue engineered auricle-A model tested in rabbits. PLoS One 8, e71667, 2013.
27. Institute of Laboratory Animal Research Committee. Guide for the Care and Use of Laboratory Animals: Eighth Edition. Washington DC: The National Academies Press, 2011, p. 118.
28. Chang, S.C.N., Tobias, G., Roy, A.K., Vacanti, C.A., and Bonassar, L.J. Tissue engineering of autologous cartilage for craniofacial reconstruction by injection molding. Plast Reconstr Surg 112, 793, 2003.
29. Elsdale, T., and Bard, J. Collagen substrata for studies on cell behavior. J Cell Biol 54, 626, 1972.
30. Bowles, R.D., Williams, R.M., Zipfel, W.R., and Bonassar, L.J. Self-assembly of aligned tissue-engineered annulus fibrosus and intervertebral disc composite via collagen gel contraction. Tissue Eng Part A 16, 1339, 2010.
31. Cross, V.L., Zheng, Y., Won Choi, N., Verbridge, S.S., Sutermaster, B.A., Bonassar, L.J., Fischbach, C., and Stroock, A.D. Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro. Biomaterials 31, 8596, 2010.
32. Ballyns, J.J., Gleghorn, J.P., Niebrzydowski, V., Rawlinson, J.J., Potter, H.G., Maher, S.A., Wright, T.M., and Bonassar, L.J. Image-guided tissue engineering of anatomically shaped implants via MRI and micro-CT using injection molding. Tissue Eng Part A 14, 1195, 2008.
33. Kim, Y.J., Sah, R.L., Doong, J.Y., and Grodzinsky, A.J. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 174, 168, 1988.
34. Enobakhare, B.O., Bader, D.L., and Lee, D.A. Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue. Anal Biochem 243, 189, 1996.
35. Neuman, R.E., and Logan, M.A. The determination of hydroxyproline. J Biol Chem 184, 299, 1950.
36. Neuman, R.E., and Logan, M.A. The determination of collagen and elastin in tissues. J Biol Chem 186, 549, 1950.
37. Bentley, J.P., and Hanson, A.N. The hydroxyproline of elastin. Biochim Biophys Acta 175, 339, 1969.
38. Puetzer, J.L., and Bonassar, L.J. High density type I collagen gels for tissue engineering of whole menisci. Acta Biomater Acta Mater 9, 7787, 2013.
39. Ibusuki, S., Halbesma, G.J., Randolph, M.A, Redmond, R.W., Kochevar, I.E., and Gill, T.J. Photochemically crosslinked collagen gels as three-dimensional scaffolds for tissue engineering. Tissue Eng 13, 1995, 2007.
40. Wollensak, G., Spoerl, E., and Seiler, T. Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 135, 620, 2003.
41. Ahearne, M., Yang, Y., Then, K.Y., and Liu, K.-K. Mechanical characterisation of UVA-riboflavin crosslinked collagen hydrogels. Br J Ophthalmol 92, 268, 2008.
42. Meretoja, V.V, Dahlin, R.L., Kasper, F.K., and Mikos, A.G. Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells. Biomaterials 33, 6362, 2012.
43. Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S., and Marshak, D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.