메뉴 건너뛰기




Volumn 375, Issue 2, 2016, Pages 384-389

Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours

Author keywords

Metastasis; Neuroblastoma; Paediatric cancer; Patient derived xenograft (PDX); Tumour microenvironment; Tumour stroma

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CHROMOGRANIN A; PROTEIN S100B; SYNAPTOPHYSIN; TYROSINE 3 MONOOXYGENASE;

EID: 84961789680     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2016.02.046     Document Type: Article
Times cited : (33)

References (37)
  • 1
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola I., Landis J. Can the pharmaceutical industry reduce attrition rates?. Nat. Rev. Drug Discov 2004, 3:711-715.
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 3
    • 84906895091 scopus 로고    scopus 로고
    • Patient-derived xenograft models: an emerging platform for translational cancer research
    • Hidalgo M., Amant F., Biankin A.V., Budinska E., Byrne A.T., Caldas C., et al. Patient-derived xenograft models: an emerging platform for translational cancer research. Cancer Discov 2014, 4:998-1013.
    • (2014) Cancer Discov , vol.4 , pp. 998-1013
    • Hidalgo, M.1    Amant, F.2    Biankin, A.V.3    Budinska, E.4    Byrne, A.T.5    Caldas, C.6
  • 5
    • 84883477300 scopus 로고    scopus 로고
    • Patient-derived tumor xenografts: transforming clinical samples into mouse models
    • Siolas D., Hannon G.J. Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer Res 2013, 73:5315-5319.
    • (2013) Cancer Res , vol.73 , pp. 5315-5319
    • Siolas, D.1    Hannon, G.J.2
  • 6
    • 84906790811 scopus 로고    scopus 로고
    • Advances in patient-derived tumor xenografts: from target identification to predicting clinical response rates in oncology
    • Rosfjord E., Lucas J., Li G., Gerber H.P. Advances in patient-derived tumor xenografts: from target identification to predicting clinical response rates in oncology. Biochem. Pharmacol 2014, 91:135-143.
    • (2014) Biochem. Pharmacol , vol.91 , pp. 135-143
    • Rosfjord, E.1    Lucas, J.2    Li, G.3    Gerber, H.P.4
  • 7
    • 84878251843 scopus 로고    scopus 로고
    • Neuroblastoma: developmental biology, cancer genomics and immunotherapy
    • Cheung N.K., Dyer M.A. Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nat. Rev. Cancer 2013, 13:397-411.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 397-411
    • Cheung, N.K.1    Dyer, M.A.2
  • 9
    • 84918532694 scopus 로고    scopus 로고
    • Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours
    • Braekeveldt N., Wigerup C., Gisselsson D., Mohlin S., Merselius M., Beckman S., et al. Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours. Int. J. Cancer 2015, 136:E252-E261.
    • (2015) Int. J. Cancer , vol.136 , pp. E252-E261
    • Braekeveldt, N.1    Wigerup, C.2    Gisselsson, D.3    Mohlin, S.4    Merselius, M.5    Beckman, S.6
  • 11
    • 84925611946 scopus 로고    scopus 로고
    • Microenvironmental regulation of therapeutic response in cancer
    • Klemm F., Joyce J.A. Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol 2015, 25:198-213.
    • (2015) Trends Cell Biol , vol.25 , pp. 198-213
    • Klemm, F.1    Joyce, J.A.2
  • 12
    • 84933050304 scopus 로고    scopus 로고
    • The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
    • Barker H.E., Paget J.T., Khan A.A., Harrington K.J. The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Nat. Rev. Cancer 2015, 15:409-425.
    • (2015) Nat. Rev. Cancer , vol.15 , pp. 409-425
    • Barker, H.E.1    Paget, J.T.2    Khan, A.A.3    Harrington, K.J.4
  • 13
    • 75349091751 scopus 로고    scopus 로고
    • Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
    • Charles N., Ozawa T., Squatrito M., Bleau A.M., Brennan C.W., Hambardzumyan D., et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell 2010, 6:141-152.
    • (2010) Cell Stem Cell , vol.6 , pp. 141-152
    • Charles, N.1    Ozawa, T.2    Squatrito, M.3    Bleau, A.M.4    Brennan, C.W.5    Hambardzumyan, D.6
  • 15
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: interactions with the tumor stroma
    • Pietras K., Ostman A. Hallmarks of cancer: interactions with the tumor stroma. Exp. Cell Res 2010, 316:1324-1331.
    • (2010) Exp. Cell Res , vol.316 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 16
    • 0030034892 scopus 로고    scopus 로고
    • Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma
    • Meitar D., Crawford S.E., Rademaker A.W., Cohn S.L. Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma. J. Clin. Oncol 1996, 14:405-414.
    • (1996) J. Clin. Oncol , vol.14 , pp. 405-414
    • Meitar, D.1    Crawford, S.E.2    Rademaker, A.W.3    Cohn, S.L.4
  • 17
    • 79952158138 scopus 로고    scopus 로고
    • Podoplanin and LYVE-1 expression in lymphatic vessels of human neuroblastoma
    • Ribatti D., Nico B., Cimpean A.M., Raica M. Podoplanin and LYVE-1 expression in lymphatic vessels of human neuroblastoma. J. Neurooncol 2010, 100:151-152.
    • (2010) J. Neurooncol , vol.100 , pp. 151-152
    • Ribatti, D.1    Nico, B.2    Cimpean, A.M.3    Raica, M.4
  • 18
    • 84867052186 scopus 로고    scopus 로고
    • Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    • Asgharzadeh S., Salo J.A., Ji L., Oberthuer A., Fischer M., Berthold F., et al. Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma. J. Clin. Oncol 2012, 30:3525-3532.
    • (2012) J. Clin. Oncol , vol.30 , pp. 3525-3532
    • Asgharzadeh, S.1    Salo, J.A.2    Ji, L.3    Oberthuer, A.4    Fischer, M.5    Berthold, F.6
  • 19
    • 33646240157 scopus 로고    scopus 로고
    • Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors
    • Vakkila J., Jaffe R., Michelow M., Lotze M.T. Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors. Clin. Cancer Res 2006, 12:2049-2054.
    • (2006) Clin. Cancer Res , vol.12 , pp. 2049-2054
    • Vakkila, J.1    Jaffe, R.2    Michelow, M.3    Lotze, M.T.4
  • 20
    • 67650688575 scopus 로고    scopus 로고
    • Presence of cancer-associated fibroblasts inversely correlates with Schwannian stroma in neuroblastoma tumors
    • Zeine R., Salwen H.R., Peddinti R., Tian Y., Guerrero L., Yang Q., et al. Presence of cancer-associated fibroblasts inversely correlates with Schwannian stroma in neuroblastoma tumors. Mod. Pathol 2009, 22:950-958.
    • (2009) Mod. Pathol , vol.22 , pp. 950-958
    • Zeine, R.1    Salwen, H.R.2    Peddinti, R.3    Tian, Y.4    Guerrero, L.5    Yang, Q.6
  • 21
    • 0033565765 scopus 로고    scopus 로고
    • The International Neuroblastoma Pathology Classification (the Shimada system)
    • Shimada H., Ambros I.M., Dehner L.P., Hata J., Joshi V.V., Roald B., et al. The International Neuroblastoma Pathology Classification (the Shimada system). Cancer 1999, 86:364-372.
    • (1999) Cancer , vol.86 , pp. 364-372
    • Shimada, H.1    Ambros, I.M.2    Dehner, L.P.3    Hata, J.4    Joshi, V.V.5    Roald, B.6
  • 22
    • 0021226066 scopus 로고
    • Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas
    • Shimada H., Chatten J., Newton W.A., Sachs N., Hamoudi A.B., Chiba T., et al. Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas. J. Natl. Cancer Inst 1984, 73:405-416.
    • (1984) J. Natl. Cancer Inst , vol.73 , pp. 405-416
    • Shimada, H.1    Chatten, J.2    Newton, W.A.3    Sachs, N.4    Hamoudi, A.B.5    Chiba, T.6
  • 23
    • 84929027817 scopus 로고    scopus 로고
    • Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration
    • Berbegall A.P., Villamon E., Tadeo I., Martinsson T., Canete A., Castel V., et al. Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration. Neoplasia 2014, 16:471-480.
    • (2014) Neoplasia , vol.16 , pp. 471-480
    • Berbegall, A.P.1    Villamon, E.2    Tadeo, I.3    Martinsson, T.4    Canete, A.5    Castel, V.6
  • 24
    • 84894122163 scopus 로고    scopus 로고
    • Quantitative modeling of clinical, cellular, and extracellular matrix variables suggest prognostic indicators in cancer: a model in neuroblastoma
    • Tadeo I., Piqueras M., Montaner D., Villamon E., Berbegall A.P., Canete A., et al. Quantitative modeling of clinical, cellular, and extracellular matrix variables suggest prognostic indicators in cancer: a model in neuroblastoma. Pediatr. Res 2014, 75:302-314.
    • (2014) Pediatr. Res , vol.75 , pp. 302-314
    • Tadeo, I.1    Piqueras, M.2    Montaner, D.3    Villamon, E.4    Berbegall, A.P.5    Canete, A.6
  • 25
    • 0037238131 scopus 로고    scopus 로고
    • The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1
    • Jackson D.G. The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1. Trends Cardiovasc. Med 2003, 13:1-7.
    • (2003) Trends Cardiovasc. Med , vol.13 , pp. 1-7
    • Jackson, D.G.1
  • 26
    • 84859936291 scopus 로고    scopus 로고
    • LYVE-1 upregulation and lymphatic invasion correlate with adverse prognostic factors and lymph node metastasis in neuroblastoma
    • Ramani P., Dungwa J.V., May M.T. LYVE-1 upregulation and lymphatic invasion correlate with adverse prognostic factors and lymph node metastasis in neuroblastoma. Virchows Arch 2012, 460:183-191.
    • (2012) Virchows Arch , vol.460 , pp. 183-191
    • Ramani, P.1    Dungwa, J.V.2    May, M.T.3
  • 27
    • 33744944082 scopus 로고    scopus 로고
    • Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
    • Bossen C., Ingold K., Tardivel A., Bodmer J.L., Gaide O., Hertig S., et al. Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J. Biol. Chem 2006, 281:13964-13971.
    • (2006) J. Biol. Chem , vol.281 , pp. 13964-13971
    • Bossen, C.1    Ingold, K.2    Tardivel, A.3    Bodmer, J.L.4    Gaide, O.5    Hertig, S.6
  • 28
    • 81255135837 scopus 로고    scopus 로고
    • Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
    • DeRose Y.S., Wang G., Lin Y.C., Bernard P.S., Buys S.S., Ebbert M.T., et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat. Med 2011, 17:1514-1520.
    • (2011) Nat. Med , vol.17 , pp. 1514-1520
    • DeRose, Y.S.1    Wang, G.2    Lin, Y.C.3    Bernard, P.S.4    Buys, S.S.5    Ebbert, M.T.6
  • 29
    • 1642389964 scopus 로고    scopus 로고
    • Short-term human prostate primary xenografts: an in vivo model of human prostate cancer vasculature and angiogenesis
    • Gray D.R., Huss W.J., Yau J.M., Durham L.E., Werdin E.S., Funkhouser W.K., et al. Short-term human prostate primary xenografts: an in vivo model of human prostate cancer vasculature and angiogenesis. Cancer Res 2004, 64:1712-1721.
    • (2004) Cancer Res , vol.64 , pp. 1712-1721
    • Gray, D.R.1    Huss, W.J.2    Yau, J.M.3    Durham, L.E.4    Werdin, E.S.5    Funkhouser, W.K.6
  • 30
    • 80052838187 scopus 로고    scopus 로고
    • Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis
    • Bankert R.B., Balu-Iyer S.V., Odunsi K., Shultz L.D., Kelleher R.J., Barnas J.L., et al. Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis. PLoS ONE 2011, 6:e24420.
    • (2011) PLoS ONE , vol.6 , pp. e24420
    • Bankert, R.B.1    Balu-Iyer, S.V.2    Odunsi, K.3    Shultz, L.D.4    Kelleher, R.J.5    Barnas, J.L.6
  • 31
    • 45549083809 scopus 로고    scopus 로고
    • Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice
    • Simpson-Abelson M.R., Sonnenberg G.F., Takita H., Yokota S.J., Conway T.F., Kelleher R.J., et al. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. J. Immunol 2008, 180:7009-7018.
    • (2008) J. Immunol , vol.180 , pp. 7009-7018
    • Simpson-Abelson, M.R.1    Sonnenberg, G.F.2    Takita, H.3    Yokota, S.J.4    Conway, T.F.5    Kelleher, R.J.6
  • 32
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 33
    • 84896747626 scopus 로고    scopus 로고
    • Mechanisms of lymphatic metastasis
    • Karaman S., Detmar M. Mechanisms of lymphatic metastasis. J. Clin. Invest 2014, 124:922-928.
    • (2014) J. Clin. Invest , vol.124 , pp. 922-928
    • Karaman, S.1    Detmar, M.2
  • 34
    • 80052265350 scopus 로고    scopus 로고
    • Humanized tumor mice - a new model to study and manipulate the immune response in advanced cancer therapy
    • Wege A.K., Ernst W., Eckl J., Frankenberger B., Vollmann-Zwerenz A., Mannel D.N., et al. Humanized tumor mice - a new model to study and manipulate the immune response in advanced cancer therapy. Int. J. Cancer 2011, 129:2194-2206.
    • (2011) Int. J. Cancer , vol.129 , pp. 2194-2206
    • Wege, A.K.1    Ernst, W.2    Eckl, J.3    Frankenberger, B.4    Vollmann-Zwerenz, A.5    Mannel, D.N.6
  • 35
    • 84861801527 scopus 로고    scopus 로고
    • IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity
    • Liu D., Song L., Wei J., Courtney A.N., Gao X., Marinova E., et al. IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity. J. Clin. Invest 2012, 122:2221-2233.
    • (2012) J. Clin. Invest , vol.122 , pp. 2221-2233
    • Liu, D.1    Song, L.2    Wei, J.3    Courtney, A.N.4    Gao, X.5    Marinova, E.6
  • 37
    • 84955377769 scopus 로고    scopus 로고
    • XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer
    • Morton J.J., Bird G., Keysar S.B., Astling D.P., Lyons T.R., Anderson R.T., et al. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene 2016, 35:290-300.
    • (2016) Oncogene , vol.35 , pp. 290-300
    • Morton, J.J.1    Bird, G.2    Keysar, S.B.3    Astling, D.P.4    Lyons, T.R.5    Anderson, R.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.