Molecular discriminators of racial disparities in prostate cancer

Trends in Cancer

Volumn 2, Issue 3, 2016, Pages 116-120

  Ateeq, Bushra ^a   Bhatia, Vipul ^a   Goel, Sakshi ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

8q24 locus; prostate cancer; SPINK1; SPOP; TMPRSS2 ERG

Indexed keywords

CANCER GROWTH; CANCER SUSCEPTIBILITY; CANCER THERAPY; ETHNIC DIFFERENCE; ETHNIC GROUP; FUSION GENE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; PROSTATE CANCER; REVIEW; SPINK1 GENE; TMPRSS2 ERG FUSION GENE; ANCESTRY GROUP; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; MALE; PROSTATE TUMOR;

APROTININ; ERG PROTEIN, HUMAN; SERINE PROTEINASE; SPINK1 PROTEIN, HUMAN; TMPRSS2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR ERG;

CONTINENTAL POPULATION GROUPS; ETHNIC GROUPS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PROSTATIC NEOPLASMS; SERINE ENDOPEPTIDASES; TRANSCRIPTIONAL REGULATOR ERG; TRYPSIN INHIBITOR, KAZAL PANCREATIC;

EID: 84961786667     PISSN: 24058033     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trecan.2016.01.005     Document Type: Short Survey

References (14)

1. Cancer Genome Atlas Research Network The molecular taxonomy of primary prostate cancer Cell 163 2015 1011 1025
2. K. Ito Prostate cancer in Asian men Nat. Rev. Urol. 11 2014 197 212
3. S.A. Tomlins, and et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer Science 310 2005 644 648
4. B. Ateeq, and et al. Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India Prostate 75 2015 1051 1062
5. M.L. Freedman, and et al. Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men Proc. Natl. Acad. Sci. U.S.A. 103 2006 14068 14073
6. L.T. Amundadottir, and et al. A common variant associated with prostate cancer in European and African populations Nat. Genet. 38 2006 652 658
7. N. Ahmadiyeh, and et al. 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC Proc. Natl. Acad. Sci. U.S.A. 107 2010 9742 9746
8. D. Robinson, and et al. Integrative clinical genomics of advanced prostate cancer Cell 161 2015 1215 1228
9. P. Rosen, and et al. Differences in frequency of ERG oncoprotein expression between index tumors of Caucasian and African American patients with prostate cancer Urology 80 2012 749 753
10. C. Magi-Galluzzi, and et al. TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of Caucasian, African-American and Japanese patients Prostate 71 2010 489 497
11. F. Khani, and et al. Evidence for molecular differences in prostate cancer between African American and Caucasian men Clin. Cancer Res. 20 2014 4925 4934
12. C.E. Barbieri, and et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer Nat. Genet. 44 2012 685 689
13. R.S. Mani, and et al. Induced chromosomal proximity and gene fusions in prostate cancer Science 326 2009 1230
14. N.C. Bastus, and et al. Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells Cancer Res. 70 2010 9544 9548