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Volumn 15, Issue 4, 2016, Pages 292-

Open Lab as a source of hits and leads against tuberculosis, malaria and kinetoplastid diseases

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ANTITRYPANOSOMAL AGENT; CLAVULANIC ACID; MEROPENEM; MEROPENEM PLUS CLAVULANATE; TAFENOQUINE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

EID: 84961763041     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd.2016.51     Document Type: Letter
Times cited : (9)

References (10)
  • 1
    • 84946483813 scopus 로고    scopus 로고
    • Hit and lead criteria in drug discovery for infectious diseases of the developing world
    • Katsuno, K. et al. Hit and lead criteria in drug discovery for infectious diseases of the developing world. Nat. Rev. Drug Discov. 14, 751-758 (2015).
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 751-758
    • Katsuno, K.1
  • 2
    • 77952704258 scopus 로고    scopus 로고
    • Thousands of chemical starting points for antimalarial lead identification
    • Gamo, F. J. et al. Thousands of chemical starting points for antimalarial lead identification. Nature 465, 305-310 (2010).
    • (2010) Nature , vol.465 , pp. 305-310
    • Gamo, F.J.1
  • 3
    • 84873811860 scopus 로고    scopus 로고
    • Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis
    • Ballell, L. et al. Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis. ChemMedChem. 8, 313-321 (2013).
    • (2013) ChemMedChem. , vol.8 , pp. 313-321
    • Ballell, L.1
  • 4
    • 84924658062 scopus 로고    scopus 로고
    • New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: An open resource
    • Peña, I. et al. New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: An open resource. Sci. Rep. 5, 8771 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 8771
    • Peña, I.1
  • 5
    • 84943338940 scopus 로고    scopus 로고
    • A new set of chemical starting points with Plasmodium falciparum transmission-blocking potential for antimalarial drug discovery
    • Almela, M. J. et al. A new set of chemical starting points with Plasmodium falciparum transmission-blocking potential for antimalarial drug discovery. PLoS ONE. 10, e0135139 (2015).
    • (2015) PLoS ONE. , vol.10 , pp. e0135139
    • Almela, M.J.1
  • 6
    • 84859798468 scopus 로고    scopus 로고
    • 3,5-diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential
    • Younis, Y. et al. 3,5-diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential. J. Med. Chem. 55, 3479-3487 (2012).
    • (2012) J. Med. Chem. , vol.55 , pp. 3479-3487
    • Younis, Y.1
  • 7
    • 84937141039 scopus 로고    scopus 로고
    • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
    • Phillips, M. A. et al. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci. Transl Med. 55, 296ra111 (2015).
    • (2015) Sci. Transl Med. , vol.55 , pp. 296-311
    • Phillips, M.A.1
  • 8
    • 84962300370 scopus 로고    scopus 로고
    • THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria
    • Cox, J. A. G. et al. THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nat. Microbiol. 1, 15006 (2016).
    • (2016) Nat. Microbiol. , vol.1 , pp. 15006
    • Cox, J.A.G.1
  • 9
    • 84931266412 scopus 로고    scopus 로고
    • Identification of Plasmodium PI4 kinase as target of MMV390048 by chemoproteomics
    • Ghidelli-Disse, S. et al. Identification of Plasmodium PI4 kinase as target of MMV390048 by chemoproteomics. Malar. J. 13 (Suppl. 1), P38 (2014).
    • (2014) Malar. J. , vol.13 , pp. 38
    • Ghidelli-Disse, S.1
  • 10
    • 84871764621 scopus 로고    scopus 로고
    • Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. Tuberculosis QcrB
    • Abrahams, K. A. et al. Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB. PLoS ONE. 7, e52951 (2012).
    • (2012) PLoS ONE. , vol.7 , pp. e52951
    • Abrahams, K.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.