메뉴 건너뛰기




Volumn 41, Issue 2, 2016, Pages 180-188

Effect of Aloe vera on glycaemic control in prediabetes and type 2 diabetes: A systematic review and meta-analysis

Author keywords

Aloe vera; diabetes mellitus; glycaemic control; prediabetes; systematic review

Indexed keywords

ALOE VERA EXTRACT; GLUCOSE; HEMOGLOBIN A1C; PLACEBO; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HERBACEOUS AGENT;

EID: 84961753545     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/jcpt.12382     Document Type: Review
Times cited : (39)

References (38)
  • 1
    • 77956392948 scopus 로고    scopus 로고
    • Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus
    • Tripathy D, Chavez AO,. Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus. Curr DiabRep, 2010; 10: 184-191.
    • (2010) Curr DiabRep , vol.10 , pp. 184-191
    • Tripathy, D.1    Chavez, A.O.2
  • 2
    • 84930465070 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2015
    • American Diabetes Association.
    • American Diabetes Association. Standards of medical care in diabetes-2015. Diabetes Care, 2015; 38 (Suppl 1): S1-S93.
    • (2015) Diabetes Care , vol.38 , pp. S1-S93
  • 4
    • 84906935517 scopus 로고    scopus 로고
    • The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations
    • Ezuruike UF, Prieto JM,. The use of plants in the traditional management of diabetes in Nigeria: pharmacological and toxicological considerations. J Ethnopharmacol, 2014; 155: 857-924.
    • (2014) J Ethnopharmacol , vol.155 , pp. 857-924
    • Ezuruike, U.F.1    Prieto, J.M.2
  • 5
    • 84891496535 scopus 로고    scopus 로고
    • Ethnomedicinal application of native remedies used against diabetes and related complications in Mauritius
    • Mootoosamy A, Fawzi Mahomoodally M,. Ethnomedicinal application of native remedies used against diabetes and related complications in Mauritius. J Ethnopharmacol, 2014; 151: 413-444.
    • (2014) J Ethnopharmacol , vol.151 , pp. 413-444
    • Mootoosamy, A.1    Fawzi Mahomoodally, M.2
  • 6
    • 18044363640 scopus 로고    scopus 로고
    • Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats
    • Rajasekaran S, Sivagnanam K, Subramanian S,. Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats. Pharmacol Rep, 2005; 57: 90-96.
    • (2005) Pharmacol Rep , vol.57 , pp. 90-96
    • Rajasekaran, S.1    Sivagnanam, K.2    Subramanian, S.3
  • 7
    • 28644434365 scopus 로고    scopus 로고
    • Mineral contents of Aloe vera leaf gel and their role on streptozotocin-induced diabetic rats
    • Rajasekaran S, Sivagnanam K, Subramanian S,. Mineral contents of Aloe vera leaf gel and their role on streptozotocin-induced diabetic rats. Biol Trace Elem Res, 2005; 108: 185-195.
    • (2005) Biol Trace Elem Res , vol.108 , pp. 185-195
    • Rajasekaran, S.1    Sivagnanam, K.2    Subramanian, S.3
  • 8
    • 55749098476 scopus 로고    scopus 로고
    • Administration of phytosterols isolated from Aloe vera gel reduce visceral fat mass and improve hyperglycemia in Zucker diabetic fatty (ZDF) rats
    • Misawa E, Tanaka M, Nomaguchi K, Yamada M, Toida T, Takase M, Iwatsuki K, Kawada T,. Administration of phytosterols isolated from Aloe vera gel reduce visceral fat mass and improve hyperglycemia in Zucker diabetic fatty (ZDF) rats. Obes Res Clin Prac, 2008; 2: 239-245.
    • (2008) Obes Res Clin Prac , vol.2 , pp. 239-245
    • Misawa, E.1    Tanaka, M.2    Nomaguchi, K.3    Yamada, M.4    Toida, T.5    Takase, M.6    Iwatsuki, K.7    Kawada, T.8
  • 9
    • 67650568107 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus
    • Kim K, Kim H, Kwon J, et al,. Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine, 2009; 16: 856-863.
    • (2009) Phytomedicine , vol.16 , pp. 856-863
    • Kim, K.1    Kim, H.2    Kwon, J.3
  • 10
    • 77957331587 scopus 로고    scopus 로고
    • Down-regulation of adipogenesis and hyperglycemia in diet-induced obesity mouse model by Aloe QDM
    • Kong H, Lee S, Shin S, et al,. Down-regulation of adipogenesis and hyperglycemia in diet-induced obesity mouse model by Aloe QDM. Biomol Ther, 2010; 18: 336-342.
    • (2010) Biomol Ther , vol.18 , pp. 336-342
    • Kong, H.1    Lee, S.2    Shin, S.3
  • 11
    • 84869223441 scopus 로고    scopus 로고
    • Dietary aloe improves insulin sensitivity via the suppression of obesity-induced inflammation in obese mice
    • Shin E, Shim KS, Kong H, et al,. Dietary aloe improves insulin sensitivity via the suppression of obesity-induced inflammation in obese mice. Immune Netw, 2011; 11: 59-67.
    • (2011) Immune Netw , vol.11 , pp. 59-67
    • Shin, E.1    Shim, K.S.2    Kong, H.3
  • 12
    • 84870720646 scopus 로고    scopus 로고
    • Dietary aloe reduces adipogenesis via the activation of AMPK and suppresses obesity-related inflammation in obese mice
    • Shin E, Shin S, Kong H, et al,. Dietary aloe reduces adipogenesis via the activation of AMPK and suppresses obesity-related inflammation in obese mice. Immune Netw, 2011; 11: 107-113.
    • (2011) Immune Netw , vol.11 , pp. 107-113
    • Shin, E.1    Shin, S.2    Kong, H.3
  • 13
    • 84863346623 scopus 로고    scopus 로고
    • Oral ingestion of Aloe vera phytosterols alters hepatic gene expression profiles and ameliorates obesity-associated metabolic disorders in zucker diabetic fatty rats
    • Misawa E, Tanaka M, Nomaguchi K, Nabeshima K, Yamada M, Toida T, Iwatsuki K,. Oral ingestion of Aloe vera phytosterols alters hepatic gene expression profiles and ameliorates obesity-associated metabolic disorders in zucker diabetic fatty rats. J Agric Food Chem, 2012; 60: 2799-2806.
    • (2012) J Agric Food Chem , vol.60 , pp. 2799-2806
    • Misawa, E.1    Tanaka, M.2    Nomaguchi, K.3    Nabeshima, K.4    Yamada, M.5    Toida, T.6    Iwatsuki, K.7
  • 14
    • 84901204629 scopus 로고    scopus 로고
    • Suppression of gut glucose absorption and enhancement of gut fluid absorption in Alloxan - Induced diabetic rats treated with crude Aloe vera gel
    • Akpan UP, Nna VU, Ofem OE, Antai AB, Osim EE,. Suppression of gut glucose absorption and enhancement of gut fluid absorption in Alloxan-induced diabetic rats treated with crude Aloe vera gel. Res J Pharm, Biol Chem Sci, 2014; 5: 647-655.
    • (2014) Res J Pharm, Biol Chem Sci , vol.5 , pp. 647-655
    • Akpan, U.P.1    Nna, V.U.2    Ofem, O.E.3    Antai, A.B.4    Osim, E.E.5
  • 15
    • 0021927458 scopus 로고
    • Prevention of atheromatous heart disease
    • Agarwal OP,. Prevention of atheromatous heart disease. Angiology, 1985; 36: 485-492.
    • (1985) Angiology , vol.36 , pp. 485-492
    • Agarwal, O.P.1
  • 16
  • 18
    • 0001760557 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera L. Juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide
    • Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O,. Antidiabetic activity of Aloe vera L. juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine, 1996; 3: 245-248.
    • (1996) Phytomedicine , vol.3 , pp. 245-248
    • Bunyapraphatsara, N.1    Yongchaiyudha, S.2    Rungpitarangsi, V.3    Chokechaijaroenporn, O.4
  • 20
    • 84962949537 scopus 로고    scopus 로고
    • Effect of Aloe vera in periphery nervous conduction velocity in diabetic patient
    • Liu H, Li P, Liu C,. Effect of Aloe vera in periphery nervous conduction velocity in diabetic patient. Clin Meta-Anal, 2001; 16: 682.
    • (2001) Clin Meta-Anal , vol.16 , pp. 682
    • Liu, H.1    Li, P.2    Liu, C.3
  • 21
    • 72549098607 scopus 로고    scopus 로고
    • Possible hypoglycemic effect of Aloe vera L. High molecular weight fractions on type 2 diabetic patients
    • Yagi A, Hegazy S, Kabbash A, Wahab EA,. Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients. Saudi Pharm J, 2009; 17: 209-215.
    • (2009) Saudi Pharm J , vol.17 , pp. 209-215
    • Yagi, A.1    Hegazy, S.2    Kabbash, A.3    Wahab, E.A.4
  • 23
    • 84891275275 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics
    • Choudhary M, Kochhar A, Sangha J,. Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics. J Food Sci Technol, 2014; 51: 90-96.
    • (2014) J Food Sci Technol , vol.51 , pp. 90-96
    • Choudhary, M.1    Kochhar, A.2    Sangha, J.3
  • 24
    • 84881367993 scopus 로고    scopus 로고
    • Metabolic effects of Aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: Randomized controlled trial
    • Choi HC, Kim SJ, Son KY, Oh BJ, Cho BL,. Metabolic effects of Aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: randomized controlled trial. Nutrition, 2013; 29: 1110-1114.
    • (2013) Nutrition , vol.29 , pp. 1110-1114
    • Choi, H.C.1    Kim, S.J.2    Son, K.Y.3    Oh, B.J.4    Cho, B.L.5
  • 26
    • 84927765608 scopus 로고    scopus 로고
    • Improvement of glucose and lipid profile status with Aloe vera in pre-diabetic subjects: A randomized controlled-trial
    • Alinejad-Mofrad S, Foadoddini M, Saadatjoo SA, Shayesteh M,. Improvement of glucose and lipid profile status with Aloe vera in pre-diabetic subjects: a randomized controlled-trial. J Diabet Metab Disord, 2015; 14: 1-7.
    • (2015) J Diabet Metab Disord , vol.14 , pp. 1-7
    • Alinejad-Mofrad, S.1    Foadoddini, M.2    Saadatjoo, S.A.3    Shayesteh, M.4
  • 27
    • 84962949551 scopus 로고    scopus 로고
    • Effect of aloe in early diabetic nephropathy
    • Liu H, Li P, Liu CS,. Effect of aloe in early diabetic nephropathy. J Weifang Med College, 2002; 24: 62-63.
    • (2002) J Weifang Med College , vol.24 , pp. 62-63
    • Liu, H.1    Li, P.2    Liu, C.S.3
  • 28
    • 62249115015 scopus 로고    scopus 로고
    • Efficacy of Aloe vera juice consumption on glycemic response in type-2 diabetic patients
    • Arora D, Goyal M, Agarwal RP,. Efficacy of Aloe vera juice consumption on glycemic response in type-2 diabetic patients. J Food Sci Technol, 2009; 46: 160-162.
    • (2009) J Food Sci Technol , vol.46 , pp. 160-162
    • Arora, D.1    Goyal, M.2    Agarwal, R.P.3
  • 29
    • 84858151895 scopus 로고    scopus 로고
    • Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: A randomized double-blind placebo-controlled clinical trial
    • Huseini HF, Kianbakht S, Hajiaghaee R, Dabaghian FH,. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med, 2012; 78: 311-316.
    • (2012) Planta Med , vol.78 , pp. 311-316
    • Huseini, H.F.1    Kianbakht, S.2    Hajiaghaee, R.3    Dabaghian, F.H.4
  • 30
    • 84872321574 scopus 로고    scopus 로고
    • Aloe vera leaf gel in treatment of advanced type 2 diabetes mellitus needing insulin therapy: A randomized double-blind placebo-controlled clinical trial
    • Huseini HF, Kianbakht S, Hajiaghaee R, Afkhami-Ardekani M, Bonakdaran A, Dabaghian FH,. Aloe vera leaf gel in treatment of advanced type 2 diabetes mellitus needing insulin therapy: a randomized double-blind placebo-controlled clinical trial. J Med Plants, 2012; 11: 19-27.
    • (2012) J Med Plants , vol.11 , pp. 19-27
    • Huseini, H.F.1    Kianbakht, S.2    Hajiaghaee, R.3    Afkhami-Ardekani, M.4    Bonakdaran, A.5    Dabaghian, F.H.6
  • 31
    • 84945348397 scopus 로고    scopus 로고
    • Effects of Aloe vera supplements on blood glucose level and lipid profile markers in type 2 diabetic patients - A randomized clinical trial
    • Zarrintan A, Mobasseri M, Zarrintan A, Ostadrahimi A,. Effects of Aloe vera supplements on blood glucose level and lipid profile markers in type 2 diabetic patients-a randomized clinical trial. Pharm Sci, 2015; 21: 65-71.
    • (2015) Pharm Sci , vol.21 , pp. 65-71
    • Zarrintan, A.1    Mobasseri, M.2    Zarrintan, A.3    Ostadrahimi, A.4
  • 34
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
    • Stratton IM, Adler AI, Neil HA, et al,. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. Br Med J, 2000; 321: 405-412.
    • (2000) Br Med J , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3
  • 36
    • 58149171455 scopus 로고    scopus 로고
    • An evidence-based systematic review of Aloe vera by the natural standard research collaboration
    • Ulbricht C, Armstrong J, Basch E, et al,. An evidence-based systematic review of Aloe vera by the natural standard research collaboration. J Herb Pharm, 2007; 7: 279-323.
    • (2007) J Herb Pharm , vol.7 , pp. 279-323
    • Ulbricht, C.1    Armstrong, J.2    Basch, E.3
  • 38
    • 79952196958 scopus 로고    scopus 로고
    • Oral Aloe vera for treatment of diabetes mellitus and dyslipidemia
    • Ngo MQ, Nguyen NN, Shah SA,. Oral Aloe vera for treatment of diabetes mellitus and dyslipidemia. Am J Health-Syst Pharm, 2010; 67: 1804-1811.
    • (2010) Am J Health-Syst Pharm , vol.67 , pp. 1804-1811
    • Ngo, M.Q.1    Nguyen, N.N.2    Shah, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.