Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis

Journal of Interferon and Cytokine Research

Volumn 36, Issue 3, 2016, Pages 169-179

  Kouzaki, Hideaki ^a   Matsumoto, Koji ^a   Kato, Tomohisa ^a   Tojima, Ichiro ^a   Shimizu, Shino ^a   Shimizu, Takeshi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; INTERLEUKIN 25; INTERLEUKIN 33; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 2; PURINERGIC P2Y2 RECEPTOR; THYMIC STROMAL LYMPHOPOIETIN; CYTOKINE; IL25 PROTEIN, HUMAN; IL33 PROTEIN, HUMAN; INTERLEUKIN 17;

ADULT; AGED; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHRONIC RHINOSINUSITIS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOPLASM; DISEASE SEVERITY; EOSINOPHILIC CHRONIC RHINOSINUSITIS; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; LIMIT OF DETECTION; MALE; NOSE MUCOSA; NOSE POLYP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; CASE CONTROL STUDY; CHRONIC DISEASE; EOSINOPHIL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MIDDLE AGED; NASAL POLYPS; PATHOLOGY; PRIMARY CELL CULTURE; RHINITIS; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SINUSITIS;

ADULT; AGED; CASE-CONTROL STUDIES; CHRONIC DISEASE; CYTOKINES; EOSINOPHILS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-17; INTERLEUKIN-33; MALE; MIDDLE AGED; NASAL POLYPS; PRIMARY CELL CULTURE; RECEPTOR, PAR-2; RECEPTORS, PURINERGIC P2Y2; RHINITIS; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SINUSITIS;

EID: 84961722049     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2015.0058     Document Type: Article

References (42)

1. Baba S, Kondo K, Kanaya K, Suzukawa K, Ushio M, Urata S, Asakage T, Kakigi A, Suzukawa M, Ohta K, Yamasoba T. 2014. Expression of IL-33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps. Laryngoscope 124:E115-E122.
2. Bachert C. 2006. Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 61:1280-1289.
3. Ballantyne SJ, Barlow JL, Jolin HE, Nath P, Williams AS, Chung KF, Sturton G, Wong SH, McKenzie AN. 2007. Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J Allergy Clin Immunol 120:1324-1331.
4. Bartemes KR, Kita H. 2012. Dynamic role of epitheliumderived cytokines in asthma. Clin Immunol 143:222-235.
5. Briot A, Deraison C, Lacroix M, Bonnart C, Robin A, Besson C, Dubus P, Hovnanian A. 2009. Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J Exp Med 206:1135-1147.
6. Bush RK, Prochnau JJ. 2004. Alternaria-induced asthma. J Allergy Clin Immunol 113:227-234.
7. Cao PP, Zhang YN, Liao B, Ma J, Wang BF, Wang H, Zeng M, Liu WH, Schleimer RP, Liu Z. 2014. Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not noneosinophilic, chronic rhinosinusitis with nasal polyps. Clin Exp Allergy 44:690-700.
8. Ediger D, Sin BA, Heper A, Anadolu Y, Misirligil Z. 2005. Airway inflammation in nasal polyposis: immunopathological aspects of relation to asthma. Clin Exp Allergy 35:319-326.
9. Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, Cohen N, Cervin A, Douglas R, Gevaert P, Georgalas C, Goossens H, Harvey R, Hellings P, Hopkins C, Jones N, Joos G, Kalogjera L, Kern B, Kowalski M, Price D, Riechelmann H, Schlosser R, Senior B, Thomas M, Toskala E, Voegels R, Wang de Y, Wormald PJ. 2012. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 50:1-12.
10. Foreman A, Holtappels G, Psaltis AJ, Jervis-Bardy J, Field J, Wormald PJ, Bachert C. 2011. Adaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Allergy 66:1449-1456.
11. Haenuki Y, Matsushita K, Futatsugi-Yumikura S, Ishii KJ, Kawagoe T, Imoto Y, Fujieda S, Yasuda M, Hisa Y, Akira S, Nakanishi K, Yoshimoto T. 2012. A critical role of IL-33 in experimental allergic rhinitis. J Allergy Clin Immunol 130: 184-194.
12. Hamilos DL. 2011. Chronic rhinosinusitis: epidemiology and medical management. J Allergy Clin Immunol 128:693-707.
13. Iijima K, Kobayashi T, Hara K, Kephart GM, Ziegler SF, McKenzie AN, Kita H. 2014. IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure. J Immunol 15:1549-1559.
14. Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T. 2012. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis. Clin Exp Allergy 42:218-228.
15. Kimura S, Pawankar R, Mori S, Nonaka M, Masuno S, Yagi T, Okubo K. 2011. Increased expression and role of thymic stromal lymphopoietin in nasal polyposis. Allergy Asthma Immunol Res 3:186-193.
16. Knight DA, Lim S, Scaffidi AK, Roche N, Chung KF, Stewart GA, Thompson PJ. 2001. Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma. J Allergy Clin Immunol 108:797-803.
17. Kobayashi T, Kouzaki H, Kita H. 2010. Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP. J Immunol 184:6350-6358.
18. Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H. 2011. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol 186:4375-4387.
19. Kouzaki H, O'Grady SM, Lawrence CB, Kita H. 2009. Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2. J Immunol 183:1427-1434.
20. Kouzaki H, Tojima I, Kita H, Shimizu T. 2013. Transcription of interleukin-25 and extracellular release of the protein is regulated by allergen proteases in airway epithelial cells. Am J Respir Cell Mol Biol 49:741-750.
21. Lam M, Hull L, McLachlan R, Snidvongs K, Chin D, Pratt E, Kalish L, Sacks R, Earls P, Sewell W, Harvey RJ. 2013. Clinical severity and epithelial endotypes in chronic rhinosinusitis. Int Forum Allergy Rhinol 3:121-128.
22. Larson JM. 2006. The Nikon C1si combines high spectral resolution, high sensitivity, and high acquisition speed. Cytometry A 69:825-834.
23. Lund VJ, Mackay IS. 1993. Staging in rhinosinusitis. Rhinology 107:183-184.
24. Müller T, Robaye B, Vieira RP, Ferrari D, Grimm M, Jakob T, Martin SF, Di Virgilio F, Boeynaems JM, Virchow JC, Idzko M. 2010. The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation. Allergy 65:1545-1553.
25. Nagarkar DR, Poposki JA, Tan BK, Comeau MR, Peters AT, Hulse KE, Suh LA, Norton J, Harris KE, Grammer LC, Chandra RK, Conley DB, Kern RC, Schleimer RP, Kato A. 2013. Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis. J Allergy Clin Immunol 132:593-600.
26. Oboki K, Ohno T, Kajiwara N, Arae K, Morita H, Ishii A, Nambu A, Abe T, Kiyonari H, Matsumoto K, Sudo K, Okumura K, Saito H, Nakae S. 2010. IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci U S A 107:18581-18586.
27. Préfontaine D, Nadigel J, Chouiali F, Audusseau S, Semlali A, Chakir J, Martin JG, Hamid Q. 2010. Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol 125:752-754.
28. Saenz SA, Taylor BC, Artis D. 2008. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 226:172-190.
29. Sakashita M, Yoshimoto T, Hirota T, Harada M, Okubo K, Osawa Y, Fujieda S, Nakamura Y, Yasuda K, Nakanishi K, Tamari M. 2008. Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis. Clin Exp Allergy 38:1875-1881.
30. Savinko T, Matikainen S, Saarialho-Kere U, Lehto M, Wang G, Lehtimäki S, Karisola P, Reunala T, Wolff H, Lauerma A, Alenius H. 2012. IL-33 and ST2 in atopic dermatitis: expression profiles and modulation by triggering factors. J Invest Dermatol 132:1392-1400.
31. Sejima T, Holtappels G, Kikuchi H, Imayoshi S, Ichimura K, Bachert C. 2012. Cytokine profiles in Japanese patients with chronic rhinosinusitis. Allergol Int 61:115-122.
32. Shaw JL, Fakhri S, Citardi MJ, Porter PC, Corry DB, Kheradmand F, Liu YJ, Luong A. 2013. IL-33-Responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. Am J Respir Crit Care Med 188:432-439.
33. Shikotra A, Choy DF, Ohri CM, Doran E, Butler C, Hargadon B, Shelley M, Abbas AR, Austin CD, Jackman J, Wu LC, Heaney LG, Arron JR, Bradding P. 2012. Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol 129: 104-111.
34. Shin SH, Ponikau JU, Sherris DA, Congdon D, Frigas E, Homburger HA, Swanson MC, Gleich GJ, Kita H. 2004. Chronic rhinosinusitis: an enhanced immune response to ubiquitous airborne fungi. J Allergy Clin Immunol 114:1369-1375.
35. Tokunaga T, Sakashita M, Haruna T, Asaka D, Takeno S, Ikeda H, Nakayama T, Seki N, Ito S, Murata J, Sakuma Y, Yoshida N, Terada T, Morikura I, Sakaida H, Kondo K, Teraguchi K, Okano M, Otori N, Yoshikawa M, Hirakawa K, Haruna S, Himi T, Ikeda K, Ishitoya J, Iino Y, Kawata R, Kawauchi H, Kobayashi M, Yamasoba T, Miwa T, Urashima M, Tamari M, Noguchi E, Ninomiya T, Imoto Y, Morikawa T, Tomita K, Takabayashi T, Fujieda S. 2015. Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC study. Allergy 70:995-1003.
36. Wang H, Mobini R, Fang Y, Barrenäs F, Zhang H, Xiang Z, Benson M. 2010. Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy 40:1194-1202.
37. Wang YH, Angkasekwinai P, Lu N, Voo KS, Arima K, Hanabuchi S, Hippe A, Corrigan CJ, Dong C, Homey B, Yao Z, Ying S, Huston DP, Liu YJ. 2007. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med 204: 1837-1847.
38. Wang YH, Liu YJ. 2009. Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin Exp Allergy 39:798-806.
39. Yoshida T, Matsuwaki Y, Asaka D, Hama T, Otori N, Moriyama H. 2013. The expression of protease-activated receptors in chronic rhinosinusitis. Int Arch Allergy Immunol 161:138-146.
40. Yu HS, Angkasekwinai P, Chang SH, Chung Y, Dong C. 2010. Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway. J Korean Med Sci. 25:829-834.
41. Zhang N, Van Zele T, Perez-Novo C, Van Bruaene N, Holtappels G, DeRuyck N, Van Cauwenberge P, Bachert C. 2008. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J Allergy Clin Immunol 122:961-968.
42. Ziegler SF, Artis D. 2010. Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol 11:289-293.