Optimization of novel pentablock copolymer based composite formulation for sustained delivery of peptide/protein in the treatment of ocular diseases

Journal of Microencapsulation

Volumn 33, Issue 2, 2016, Pages 103-113

  Patel, Sulabh P ^a   Vaishya, Ravi ^a   Patel, Ashaben ^a   Agrahari, Vibhuti ^a   Pal, Dhananjay ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Biodegradable; intravitreal; nanoparticles; ocular delivery; protein; sustained delivery

Indexed keywords

CATALASE; COPOLYMER; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; INSULIN; LYSOZYME; NANOPARTICLE; OCTREOTIDE; PEPTIDE; DELAYED RELEASE FORMULATION; GEL; POLYMER; PROTEIN;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; EYE DISEASE; GEL; HEAT SENSITIVITY; MOLECULAR WEIGHT; PARTICLE SIZE; SUSTAINED RELEASE FORMULATION; SYNTHESIS; ANIMAL; CHEMISTRY; CHICKEN; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; EYE DISEASES; HUMAN;

ANIMALS; CATALASE; CHICKENS; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EYE DISEASES; GELS; HUMANS; IMMUNOGLOBULIN G; INSULIN; MURAMIDASE; NANOPARTICLES; OCTREOTIDE; PEPTIDES; POLYMERS; PROTEINS;

EID: 84961721062     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2015.1134685     Document Type: Article

References (32)

1. Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology, 2007; 114: 855-9.
2. Bilati U, Allemann E, Doelker E. Sonication parameters for the preparation of biodegradable nanocapsules of controlled size by the double emulsion method. Pharm Dev Technol, 2003; 8: 1-9.
3. Bilati U, Allemann E, Doelker E. Poly(d, l-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency. J Microencapsul, 2005; 22: 205-14.
4. Frank A, Rath SK, Venkatraman SS. Controlled release from bioerodible polymers: Effect of drug type and polymer composition. J Control Release, 2005; 102: 333-44.
5. Fu K, Pack DW, Klibanov AM, Langer R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres. Pharm Res, 2000; 17: 100-6.
6. Gou M, Gong C, Zhang J, Wang X, Wang X, Gu Y, Guo G, Chen L, Luo F, Zhao X., et al. Polymeric matrix for drug delivery: Honokiol-loaded PCL-PEG-PCL nanoparticles in PEG-PCL-PEG thermosensitive hydrogel. J Biomed Mater Res A, 2010; 93: 219-26.
7. Hirani A, Grover A, Lee YW, Pathak Y, Sutariya V. Triamcinolone acetonide nanoparticles incorporated in thermoreversible gels for age-related macular degeneration. Pharm Dev Technol, 2016; 21: 61-7.
8. Huang MH, Li S, Coudane J, Vert M. Synthesis and characterization of block copolymers of e-caprolactone and d,l-lactide initiated by ethylene glycol or poly(ethylene glycol). Macromol Chem Phys, 2003; 204: 1994-2001.
9. Huang MH, Li S, Hutmacher DW, Schantz JT, Vacanti CA, Braud C, Vert M. Degradation and cell culture studies on block copolymers prepared by ring opening polymerization of epsilon-caprolactone in the presence of poly(ethylene glycol). J Biomed Mater Res A, 2004; 69: 417-27.
10. Jager RD, Aiello LP, Patel SC, Cunningham ET, Jr. Risks of intravitreous injection: A comprehensive review. Retina, 2004; 24: 676-98.
11. Jia W, Gu Y, Gou M, Dai M, Li X, Kan B, Yang J, Song Q, Wei Y, Qian Z. Preparation of biodegradable polycaprolactone/poly (ethylene glycol)/polycaprolactone (PCEC) nanoparticles. Drug Deliv, 2008; 15: 409-16.
12. Kulkarni AD, Kuppermann BD. Wet age-related macular degeneration. Adv Drug Deliv Rev, 2005; 57: 1994-2009.
13. Kumar TR, Soppimath K, Nachaegari SK. Novel delivery technologies for protein and peptide therapeutics. Curr Pharm Biotechnol, 2006; 7: 261-76.
14. Lee SH, Zhang Z, Feng SS. Nanoparticles of poly(lactide)-tocopheryl polyethylene glycol succinate (PLA-TPGS) copolymers for protein drug delivery. Biomaterials, 2007; 28: 2041-50.
15. Li S, Dobrzynski P, Kasperczyk J, Bero M, Braud C, Vert M. Structure-property relationships of copolymers obtained by ring-opening polymerization of glycolide and epsilon-caprolactone. Part 2. Influence of composition and chain microstructure on the hydrolytic degradation. Biomacromolecules, 2005; 6: 489-97.
16. Li S, Molina I, Martinez MB, Vert M. Hydrolytic and enzymatic degradations of physically crosslinked hydrogels prepared from PLA/PEO/PLA triblock copolymers. J Mater Sci Mater Med, 2002; 13: 81-6.
17. Liu CB, Gong CY, Huang MJ, Wang JW, Pan YF, Zhang YD, Li GZ, Gou ML, Wang K, Tu MJ., et al. Thermoreversible gel-sol behavior of biodegradable PCL-PEG-PCL triblock copolymer in aqueous solutions. J Biomed Mater Res Part B Appl Biomater, 2008; 84: 165-75.
18. Ozturk BT, Kerimoglu H, Bozkurt B, Okudan S. Comparison of intravitreal bevacizumab and ranibizumab treatment for diabetic macular edema. J Ocul Pharmacol Ther, 2011; 27: 373-7.
19. Perez C, Castellanos IJ, Costantino HR, Al-Azzam W, Griebenow K. Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers. J Pharm Pharmacol, 2002; 54: 301-13.
20. Peyman GA, Lad EM, Moshfeghi DM. Intravitreal injection of therapeutic agents. Retina, 2009; 29: 875-912.
21. Pistel KF, Kissel T. Effects of salt addition on the microencapsulation of proteins using W/O/W double emulsion technique. J Microencapsul, 2000; 17: 467-83.
22. Pourcelle V, Devouge S, Garinot M, Preat V, Marchand-Brynaert J. PCL-PEG-based nanoparticles grafted with GRGDS peptide: Preparation and surface analysis by XPS. Biomacromolecules, 2007; 8: 3977-83.
23. Putney SD. Encapsulation of proteins for improved delivery. Curr Opin Chem Biol, 1998; 2: 548-52.
24. Radivojsa M, Grabnar I, Ahlin Grabnar P. Thermoreversible in situ gelling poloxamer-based systems with chitosan nanocomplexes for prolonged subcutaneous delivery of heparin: Design and in vitro evaluation. Eur J Pharm Sci, 2013; 50: 93-101.
25. Sampat KM, Garg SJ. Complications of intravitreal injections. Curr Opin Ophthalmol, 2010; 21: 178-83.
26. Sayen A, Hubert I, Berrod JP. Age related macular degeneration. Rev Prat, 2011; 61: 159-64.
27. Singh S, Webster DC, Singh J. Thermosensitive polymers: Synthesis, characterization, and delivery of proteins. Int J Pharm, 2007; 341: 68-77.
28. Tang Y, Singh J. Biodegradable and biocompatible thermosensitive polymer based injectable implant for controlled release of protein. Int J Pharm, 2009; 365: 34-43.
29. Van de Weert M, Hennink WE, Jiskoot W. Protein instability in poly (lactic-co-glycolic acid) microparticles. Pharm Res, 2000; 17: 1159-67.
30. Zablotna E, Jaskiewicz A, Legowska A, Miecznikowska H, Lesner A, Rolka K. Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI-1 as a starting structure. J Pept Sci, 2007; 13: 749-55.
31. Zhang JX, Zhu KJ, Chen D. Preparation of bovine serum albumin loaded poly (d, l-lactic-co-glycolic acid) microspheres by a modified phase separation technique. J Microencapsul, 2005; 22: 117-26.
32. Zhang Y, Schwendeman SP. Minimizing acylation of peptides in PLGA microspheres. J Control Release, 2012; 162: 119-26.