Treatment outcomes of HIV-positive patients on first-line antiretroviral therapy in private versus public HIV clinics in johannesburg, South Africa

Clinical Epidemiology

Volumn 8, Issue , 2016, Pages 37-47

  Moyo, Faith ^a   Chasela, Charles ^b,c   Brennan, Alana T ^a,d   Ebrahim, Osman ^e   Sanne, Ian M ^a,f   Long, Lawrence ^a   Evans, Denise ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c HUMAN SCIENCES RESEARCH COUNCIL   (South Africa)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e Brenthurst Clinic   (South Africa)

^f HELEN JOSEPH HOSPITAL   (South Africa)

Author keywords

Attrition; Health systems; HIV programs; Viral suppression

Indexed keywords

ANTIRETROVIRUS AGENT;

ADULT; ANEMIA; ARTICLE; BODY MASS; CAUSE OF DEATH; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; DRUG TREATMENT FAILURE; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PRIVATE HOSPITAL; PUBLIC HOSPITAL; RETROSPECTIVE STUDY; SEX DIFFERENCE; SOUTH AFRICA; TIME TO TREATMENT; TREATMENT DURATION; TREATMENT OUTCOME; VIRUS LOAD;

EID: 84961661977     PISSN: None     EISSN: 11791349     Source Type: Journal    
DOI: 10.2147/CLEP.S93014     Document Type: Article

References (30)

1. Nglazi MD, Lawn SD, Kaplan R, et al. Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa. BMC Infect Dis. 2011;56(1):e1-e8.
2. Shah B, Walshe L, Saple DG, et al. Adherence to antiretroviral therapy and virologic suppression among HIV-infected persons receiving care in private clinics in Mumbai, India. Clin Infect Dis. 2007;44(9):1235-1244.
3. Innes C, Hamilton R, Hoffman CJ, et al. A novel HIV treatment model using private practitioners in South Africa. Sex Transm Infect. 2012;88(2):136-140.
4. Stevensi M, Sinanovici E, Regenesbergi L, Hislopii M. HIV and AIDS, STIs and TB in the private sector, 2010. Available from: http://fullnulled.com/doc/pdf/download/www_hst_org_za-uploads-files-chap14_07.pdf. Accessed December 21, 2015
5. Shet A, DeCosta A, Heylen E, Shastri S, Chandy S, Ekstrand M. High rates of adherence and treatment success in a public and public-private HIV clinic in India: potential benefits of standardized national care delivery systems. BMC Health Serv Res. 2011;11:277
6. Govindasamy D, Ford N, Kranzer K. Risk factors, barriers and facilita- tors for linkage to antiretroviral therapy care: a systematic review. AIDS. 2012;26(23):2059-2067.
7. Bekker LG, Venter F, Cohen K, et al. Provision of antiretroviral therapy in South Africa; the nuts and bolts. Antivir Ther. 2014;19(3);105-116.
8. Fox MP, Brennan A, Maskew M, MacPhail P, Sanne I. Using vital registration data to update mortality among patients lost to follow-up from ART programmes: evidence from the ThembaLethu Clinic, South Africa. Trop Med Int Health. 2010;15(4):405-413.
9. Sanne IM, Westreich D, Macphail AP, Rubel D, Majuba P. Long term outcomes of antiretroviral therapy in a large HIV/AIDS care clinic in urban South Africa: a prospective cohort study. J Int AIDS Soc. 2009;12:38.
10. Nglazi MD, Kranzer K, Holele P, Kaplan R, Mark D, Jaspan H. Ŧreatment outcomes in HIV-infected adolescents attending a community-based antiretroviral therapy clinic in South Africa. BMC Infect Dis. 2012;12(21):1471-2334.
11. Fox MP, Maskew M, MacPhail AP, et al. Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa. Int J Epidemiol. 2013;42(2):430-439
12. Scaling up antiretroviral therapy in resource-limited settings: Treatment guidelines for a public health approach 2004. Available from: http://www.who.int/hiv/pub/prev_care/en/arvrevision2003en.pdf?ua=1. Accessed December 21. 2015
13. Antiretroviral therapy for HIV infection in adults and adolescents: Recommendations for a public health approach 2010. Available from: http://www.ncbi.nlm.nih.gov/books/NBK138523#ch11.s1. Accessed December 21, 2015.
14. National antiretroviral treatment guidelines 2004. Available from: http://www0.sun.ac.za/ruralhealth/ukwandahome/rudasaresources2009/DOH/1.%20Antiretroviral.pdf. Accessed December 22, 2015
15. South African National Department of Health Antiretroviral Therapy Guidelines 2010. Available from: http://www.fidssa.co.za/­Guidelines/2010_Adult_ART_Guidelines.pdf. Accessed October 01, 2014
16. Shearer K, Brennan AT, Maskew M, et al. The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa. J Int AIDS Soc. 2014;17:19065.
17. Westreich D, Maskew M, Evans D, Firnhaber C, Majuba P, Sanne I. Incident pregnancy and time to death or AIDS among HIV-positive women receiving antiretroviral therapy. PLoS One. 2013;8(3):e58117
18. Gounden R. A clinical assessment of antiretroviral-treated patients referred from the private sector to the South African government antiretroviral (ARV) programme: a retrospective analysis. South Afr J HIV Med. 2011;12(1):8-14
19. John S, Johnson J, Majorowski M, Friedman N, Blazer C. Private sector involvement in HIV service provision. Arlington VA: US SAID|AIDSTAR-One Project Task Force Order 1. 2009. Available from: http://www.jsi.com/JSIInternet/Resources/publication/display.cfm?txtGeoArea=INTL&id=11211&thisSection=Resources. Accessed July 22 2014.
20. Somi G, Keogh SC, Todd J, et al. Low mortality risk but high loss to follow-up among patients in the Tanzanian national HIV care and treatment programme. Trop Med Int Health. 2012;17(4):497-506.
21. Lawn SD, Harries AD, Anglaret X, Myer L, Wood R. Early mortality among adults accessing antiretroviral treatment programmes in sub- Saharan Afr. J AIDS. 2008;22:1897-1908.
22. Zachariah R, Harries K, Moses M, et al. Very early mortality in patients starting antiretroviral treatment at primary health centres in rural Malawi. Trop Med Int Health. 2009;14(7):713-721.
23. Mosha F, Muchunguzi V, Matee M, et al. Gender differences in HIV disease progression and treatment outcomes among HIV patients one year after starting antiretroviral treatment (ART) in Dares Salaam, Tanzania. BMC Public Health. 2013;13:38.
24. World Health Organization. Disease Staging System for HIV Infection and Disease; 2006. Available from: http://www.who.int/hiv/pub/guidelines/clinicalstaging.pdf. Accessed April 5, 2014.
25. Stringer J, Zulu I, Levy J, et al. Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: feasibility and early outcomes. J Am Med Assoc. 2006;296(7):782-793.
26. Moshabela M, Schneider H, Cleary SM, Prony P, Eyles J. Does accessibility to antiretroviral care improve after down referral of patients from hospitals to health centres in South Africa? Af J AIDS. 2011;10(4): 393-401
27. Cornell M, Grimsrud A, Fairall L, et al. Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007. J AIDS. 2010;24(14):2263-2270.
28. Maskew M, Brennan AT, Macphail AP, Sanne IM, Fox MP. Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa. J Int Assoc Physicians AIDS Care. 2012;11(1):57-65.
29. Harries AD, Zachariah R, Lawn SD, Rosen S. Strategies to improve patient retention on antiretroviral therapy in sub-Saharan Africa. Trop Med Int Health. 2010;15(1):70-75.
30. Evans D, Menezes C, Mahomed K, et al. Treatment outcomes of HIV-infected adolescents attending public-sector HIV clinics across Gauteng and Mpumalanga, South Africa. AIDS Res Hum Retroviruses. 2013;29(6):892-900