메뉴 건너뛰기




Volumn 16, Issue 13, 2015, Pages

DMAP: A connectivity map database to enable identification of novel drug repositioning candidates

Author keywords

[No Author keywords available]

Indexed keywords

DATABASE SYSTEMS; GENE EXPRESSION; MAPS;

EID: 84961640984     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-16-S13-S4     Document Type: Article
Times cited : (42)

References (33)
  • 1
    • 79958754253 scopus 로고    scopus 로고
    • PREDICT: a method for inferring novel drug indications with application to personalized medicine
    • Gottlieb A, et al: PREDICT: a method for inferring novel drug indications with application to personalized medicine. Mol Syst Biol. 2011, 7: 496-
    • (2011) Mol Syst Biol , vol.7 , pp. 496
    • Gottlieb, A.1
  • 2
    • 84867338003 scopus 로고    scopus 로고
    • Discovery and preclinical validation of drug indications using compendia of public gene expression data
    • 96ra77
    • Sirota M, et al: Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med. 2011, 3 (96): 96ra77.-
    • (2011) Sci Transl Med , vol.3 , Issue.96
    • Sirota, M.1
  • 3
    • 77957044703 scopus 로고    scopus 로고
    • Discovery of drug mode of action and drug repositioning from transcriptional responses
    • Iorio F, et al: Discovery of drug mode of action and drug repositioning from transcriptional responses. Proc Natl Acad Sci USA. 2010, 107 (33): 14621-6.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.33 , pp. 14621-14626
    • Iorio, F.1
  • 4
    • 0037374498 scopus 로고    scopus 로고
    • The price of innovation: new estimates of drug development costs
    • DiMasi JA, RW Hansen, HG Grabowski: The price of innovation: new estimates of drug development costs. J Health Econ. 2003, 22 (2): 151-85.
    • (2003) J Health Econ , vol.22 , Issue.2 , pp. 151-185
    • DiMasi, J.A.1    RW, H.2    HG, G.3
  • 5
    • 4344668661 scopus 로고    scopus 로고
    • Drug repositioning: identifying and developing new uses for existing drugs
    • Ashburn TT, KB Thor: Drug repositioning: identifying and developing new uses for existing drugs. Nat Rev Drug Discov. 2004, 3 (8): 673-83.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.8 , pp. 673-683
    • Ashburn, T.T.1    KB, T.2
  • 6
    • 70449634957 scopus 로고    scopus 로고
    • Predicting new molecular targets for known drugs
    • Keiser MJ, et al: Predicting new molecular targets for known drugs. Nature. 2009, 462 (7270): 175-81.
    • (2009) Nature , vol.462 , Issue.7270 , pp. 175-181
    • Keiser, M.J.1
  • 7
    • 47249146126 scopus 로고    scopus 로고
    • Drug target identification using side-effect similarity
    • Campillos M, et al: Drug target identification using side-effect similarity. Science. 2008, 321 (5886): 263-6.
    • (2008) Science , vol.321 , Issue.5886 , pp. 263-266
    • Campillos, M.1
  • 8
    • 68249111344 scopus 로고    scopus 로고
    • Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts
    • Li J, X Zhu, JY Chen: Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts. PLoS Comput Biol. 2009, 5 (7): e1000450.-
    • (2009) PLoS Comput Biol , vol.5 , Issue.7 , pp. e1000450
    • Li, J.1    Zhu, X.2    JY, C.3
  • 9
    • 68449088145 scopus 로고    scopus 로고
    • Human disease-drug network based on genomic expression profiles
    • Hu G, P Agarwal: Human disease-drug network based on genomic expression profiles. PLoS One. 2009, 4 (8): e6536.-
    • (2009) PLoS One , vol.4 , Issue.8 , pp. e6536
    • Hu, G.1    Agarwal, P.2
  • 10
    • 33845876254 scopus 로고    scopus 로고
    • The Connectivity Map: a new tool for biomedical research
    • Lamb J: The Connectivity Map: a new tool for biomedical research. Nat Rev Cancer. 2007, 7 (1): 54-60.
    • (2007) Nat Rev Cancer , vol.7 , Issue.1 , pp. 54-60
    • Lamb, J.1
  • 11
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, et al: The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science. 2006, 313 (5795): 1929-35.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1929-1935
    • Lamb, J.1
  • 12
    • 33746222185 scopus 로고    scopus 로고
    • The cost of new drug discovery and development
    • Dickson M, JP Gagnon: The cost of new drug discovery and development. Discov Med. 2004, 4 (22): 172-9.
    • (2004) Discov Med , vol.4 , Issue.22 , pp. 172-179
    • Dickson, M.1    JP, G.2
  • 13
    • 79955428497 scopus 로고    scopus 로고
    • The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
    • 80ps16
    • Huang R, et al: The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics. Sci Transl Med. 2011, 3 (80): 80ps16.
    • (2011) Sci Transl Med , vol.3 , Issue.80
    • Huang, R.1
  • 14
    • 84861508376 scopus 로고    scopus 로고
    • STITCH 3: zooming in on protein-chemical interactions
    • Kuhn M, et al: STITCH 3: zooming in on protein-chemical interactions. Nucleic Acids Res. 2012, 40 (Database): D876-80.
    • (2012) Nucleic Acids Res , vol.40 , Issue.DATABASE , pp. D876-D880
    • Kuhn, M.1
  • 15
    • 84941026118 scopus 로고    scopus 로고
    • The Comparative Toxicogenomics Database's 10th year anniversary: update 2015
    • Davis AP, et al: The Comparative Toxicogenomics Database's 10th year anniversary: update 2015. Nucleic Acids Res. 2015, 43 (Database): D914-20.
    • (2015) Nucleic Acids Res , vol.43 , Issue.DATABASE , pp. D914-D920
    • Davis, A.P.1
  • 16
    • 63549137956 scopus 로고    scopus 로고
    • HAPPI: an online database of comprehensive human annotated and predicted protein interactions
    • Chen JY, S Mamidipalli, T Huan: HAPPI: an online database of comprehensive human annotated and predicted protein interactions. BMC Genomics. 2009, 10 (Suppl 1): S16.-
    • (2009) BMC Genomics , vol.10 , pp. S16
    • Chen, J.Y.1    Mamidipalli, S.2    Huan, T.3
  • 17
    • 39049189899 scopus 로고    scopus 로고
    • Mining Alzheimer disease relevant proteins from integrated protein interactome data
    • Chen JY, C Shen, AY Sivachenko: Mining Alzheimer disease relevant proteins from integrated protein interactome data. Pac Symp Biocomput. 2006, 367-78.
    • (2006) Pac Symp Biocomput , pp. 367-378
    • Chen, J.Y.1    Shen, C.2    Sivachenko, A.Y.3
  • 18
    • 75549090848 scopus 로고    scopus 로고
    • Update of TTD: Therapeutic Target Database
    • Zhu F, et al: Update of TTD: Therapeutic Target Database. Nucleic Acids Res. 2010, 38 (Database): D787-91.
    • (2010) Nucleic Acids Res , vol.38 , Issue.DATABASE , pp. D787-D791
    • Zhu, F.1
  • 19
    • 84871748184 scopus 로고    scopus 로고
    • DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
    • Pacini C, et al: DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data. Bioinformatics. 2013, 29 (1): 132-4.
    • (2013) Bioinformatics , vol.29 , Issue.1 , pp. 132-134
    • Pacini, C.1
  • 20
    • 84874271270 scopus 로고    scopus 로고
    • NCBI GEO: archive for functional genomics data sets--update
    • Barrett T, et al: NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013, 41 (D1): D991-5.
    • (2013) Nucleic Acids Res , vol.41 , Issue.D1 , pp. D991-D995
    • Barrett, T.1
  • 21
    • 12344280017 scopus 로고    scopus 로고
    • Summaries of Affymetrix GeneChip probe level data
    • Irizarry RA, et al: Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 2003, 31 (4): e15.-
    • (2003) Nucleic Acids Res , vol.31 , Issue.4 , pp. e15
    • Irizarry, R.A.1
  • 22
    • 27844594381 scopus 로고    scopus 로고
    • Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
    • Warnat P, R Eils, B Brors: Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes. BMC Bioinformatics. 2005, 6: 265-
    • (2005) BMC Bioinformatics , vol.6 , pp. 265
    • Warnat, P.1    Eils, R.2    Brors, B.3
  • 23
    • 70350227039 scopus 로고    scopus 로고
    • Systematic evaluation of drug-disease relationships to identify leads for novel drug uses
    • Chiang AP, AJ Butte: Systematic evaluation of drug-disease relationships to identify leads for novel drug uses. Clin Pharmacol Ther. 2009, 86 (5): 507-10.
    • (2009) Clin Pharmacol Ther , vol.86 , Issue.5 , pp. 507-510
    • Chiang, A.P.1    AJ, B.2
  • 24
    • 84859267371 scopus 로고    scopus 로고
    • Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
    • Zhu F, et al: Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012, 40 (Database): D1128-36.
    • (2012) Nucleic Acids Res , vol.40 , Issue.DATABASE , pp. D1128-D1136
    • Zhu, F.1
  • 25
    • 34547589578 scopus 로고    scopus 로고
    • DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
    • Huang da W, et al: DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 2007, 35 (Web Server): W169-75.
    • (2007) Nucleic Acids Res , vol.35 , Issue.WEB SERVER , pp. W169-W175
    • Huang da, W.1
  • 26
    • 21244485773 scopus 로고    scopus 로고
    • The partial area under the summary ROC curve
    • Walter SD: The partial area under the summary ROC curve. Stat Med. 2005, 24 (13): 2025-40.
    • (2005) Stat Med , vol.24 , Issue.13 , pp. 2025-2040
    • Walter, S.D.1
  • 27
    • 84871511126 scopus 로고    scopus 로고
    • Deaths: Preliminary Data for 2011
    • October 10
    • Hoyert Donna, Xu Jiaquan: Deaths: Preliminary Data for 2011. National Vital Statistics Reports. 2012, 61 (6): October 10
    • (2012) National Vital Statistics Reports , vol.61 , Issue.6
    • Hoyert, D.1    Xu, J.2
  • 28
    • 84876031436 scopus 로고    scopus 로고
    • Synchronous bilateral Wilms tumor: A report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)
    • Indolfi P, et al: Synchronous bilateral Wilms tumor: A report from the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). Cancer. 2013
    • (2013) Cancer
    • Indolfi, P.1
  • 29
    • 67649415969 scopus 로고    scopus 로고
    • Therapeutic target validation of protein kinase C(PKC)-zeta for asthma using a mouse model
    • Do JS, et al: Therapeutic target validation of protein kinase C(PKC)-zeta for asthma using a mouse model. Int J Mol Med. 2009, 23 (4): 561-6.
    • (2009) Int J Mol Med , vol.23 , Issue.4 , pp. 561-566
    • Do, J.S.1
  • 30
    • 34248549442 scopus 로고    scopus 로고
    • The effects of protein kinase C (PKC) on the tension of normal and passively sensitized human airway smooth muscle and the activity of voltage-dependent delayed rectifier potassium channel (Kv)
    • Cheng D, et al: The effects of protein kinase C (PKC) on the tension of normal and passively sensitized human airway smooth muscle and the activity of voltage-dependent delayed rectifier potassium channel (Kv). J Huazhong Univ Sci Technolog Med Sci. 2007, 27 (2): 153-6.
    • (2007) J Huazhong Univ Sci Technolog Med Sci , vol.27 , Issue.2 , pp. 153-156
    • Cheng, D.1
  • 31
    • 0019774112 scopus 로고
    • A calcium antagonist, nifedipine, modifies exercise-induced asthma
    • Barnes PJ, NM Wilson, MJ Brown: A calcium antagonist, nifedipine, modifies exercise-induced asthma. Thorax. 1981, 36 (10): 726-30.
    • (1981) Thorax , vol.36 , Issue.10 , pp. 726-730
    • Barnes, P.J.1    NM, W.2    MJ, B.3
  • 32
    • 0030775651 scopus 로고    scopus 로고
    • Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1)
    • Groshong SD, et al: Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Mol Endocrinol. 1997, 11 (11): 1593-607.
    • (1997) Mol Endocrinol , vol.11 , Issue.11 , pp. 1593-1607
    • Groshong, S.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.