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Volumn 16, Issue 5, 2016, Pages 591-593

Antibody-drug conjugates for non-oncological indications

Author keywords

ADCs; Antibody drug conjugates; non oncology

Indexed keywords

CYTOTOXIC AGENT; DRUG ANTIBODY; ANTIINFECTIVE AGENT; IMMUNOTOXIN;

EID: 84961391260     PISSN: 14712598     EISSN: 17447682     Source Type: Journal    
DOI: 10.1517/14712598.2016.1161753     Document Type: Review
Times cited : (44)

References (13)
  • 1
    • 0343442975 scopus 로고
    • Zur Kenntnis der Antitoxinwirkung
    • Ehrlich P. Zur Kenntnis der Antitoxinwirkung. Fortschr Med. 1897; 15: 41-43.
    • (1897) Fortschr Med , vol.15 , pp. 41-43
    • Ehrlich, P.1
  • 2
    • 84943585563 scopus 로고    scopus 로고
    • Preclinical pharmacokinetic considerations for the development of antibody drug conjugates
    • Kamath AV, Iyer S. Preclinical pharmacokinetic considerations for the development of antibody drug conjugates. Pharm Res. 2015; 32: 3470-3479.
    • (2015) Pharm Res , vol.32 , pp. 3470-3479
    • Kamath, A.V.1    Iyer, S.2
  • 3
    • 84934444640 scopus 로고    scopus 로고
    • Antibody-drug conjugate (ADC) clinical pipeline: A review
    • Sassoon I, Blanc V. Antibody-drug conjugate (ADC) clinical pipeline: a review. Methods Mol Biol. 2013; 1045: 1-27.
    • (2013) Methods Mol Biol , vol.1045 , pp. 1-27
    • Sassoon, I.1    Blanc, V.2
  • 4
    • 84864550598 scopus 로고    scopus 로고
    • Targeting the hemoglobin scavenger receptor CD163 in macrophages highly increases the anti-inflammatory potency of dexamethasone
    • Graversen JH, Svendsen P, Dagnaes-Hansen F, et al. Targeting the hemoglobin scavenger receptor CD163 in macrophages highly increases the anti-inflammatory potency of dexamethasone. Mol Ther. 2012; 20: 1550-8.
    • (2012) Mol Ther , vol.20 , pp. 1550-1558
    • Graversen, J.H.1    Svendsen, P.2    Dagnaes-Hansen, F.3
  • 5
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
    • Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med. 2006; 354: 2531-2541.
    • (2006) N Engl J Med , vol.354 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2    Kantarjian, H.3
  • 6
    • 70350103708 scopus 로고    scopus 로고
    • Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia
    • Giles FJ, ODwyer M, Swords R. Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia. Leukemia. 2009; 23: 1698-1707.
    • (2009) Leukemia , vol.23 , pp. 1698-1707
    • Giles, F.J.1    Odwyer, M.2    Swords, R.3
  • 7
    • 84924690207 scopus 로고    scopus 로고
    • An immunosuppressive antibody-drug conjugate
    • Wang RE, Liu T, Wang Y, et al. An immunosuppressive antibody-drug conjugate. J Am Chem Soc. 2015; 137: 3229-32.
    • (2015) J Am Chem Soc , vol.137 , pp. 3229-3232
    • Wang, R.E.1    Liu, T.2    Wang, Y.3
  • 8
    • 84905216248 scopus 로고    scopus 로고
    • Rational design of CXCR4 specific antibodies with elongated CDRs
    • Liu T, Liu Y, Wang Y, et al. Rational design of CXCR4 specific antibodies with elongated CDRs. J Am Chem Soc. 2014; 136: 10557-10560.
    • (2014) J Am Chem Soc , vol.136 , pp. 10557-10560
    • Liu, T.1    Liu, Y.2    Wang, Y.3
  • 9
    • 49449087300 scopus 로고    scopus 로고
    • Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
    • Junutula JR, Raab H, Clark S, et al. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index. Nat Biotechnol. 2008; 26: 925-32.
    • (2008) Nat Biotechnol , vol.26 , pp. 925-932
    • Junutula, J.R.1    Raab, H.2    Clark, S.3
  • 10
    • 84867040452 scopus 로고    scopus 로고
    • Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
    • Axup JY, Bajjuri KM, Ritland M, et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proc Natl Acad Sci U S A. 2012; 109: 16101-16106.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 16101-16106
    • Axup, J.Y.1    Bajjuri, K.M.2    Ritland, M.3
  • 11
    • 84947707167 scopus 로고    scopus 로고
    • Targeted delivery of LXR agonist using a site-specific antibody-drug conjugate
    • Lim RKV, Yu S, Cheng B, et al. Targeted delivery of LXR agonist using a site-specific antibody-drug conjugate. Bioconjugate Chem. 2015; 26: 2216-2222.
    • (2015) Bioconjugate Chem , vol.26 , pp. 2216-2222
    • Lim, R.K.V.1    Yu, S.2    Cheng, B.3
  • 12
    • 84947751820 scopus 로고    scopus 로고
    • Novel antibody-antibiotic conjugate eliminates intracellular S. Aureus
    • Lehar SM, Pillow T, Xu M, et al. Novel antibody-antibiotic conjugate eliminates intracellular S. aureus. Nature. 2015; 527: 323-328.
    • (2015) Nature , vol.527 , pp. 323-328
    • Lehar, S.M.1    Pillow, T.2    Xu, M.3
  • 13
    • 84903762549 scopus 로고    scopus 로고
    • Antibody-drug conjugates: Current status and future directions
    • Perez HL, Cardarelli PM, Deshpande S, et al. Antibody-drug conjugates: current status and future directions. Drug Discov Today. 2014; 19: 869-881.
    • (2014) Drug Discov Today , vol.19 , pp. 869-881
    • Perez, H.L.1    Cardarelli, P.M.2    Deshpande, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.