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Volumn 56, Issue 4, 2015, Pages 268-274

The skin microbiome: Associations between altered microbial communities and disease

Author keywords

acne; atopic dermatitis; bacteria; chronic wound; dermatology; psoriasis; skin microbiome

Indexed keywords

ACNE VULGARIS; ATOPIC DERMATITIS; BACTERIAL LOAD; CHRONIC WOUND; COMMENSAL; DISEASE ASSOCIATION; DISEASE EXACERBATION; DNA EXTRACTION; DNA SEQUENCE; HUMAN; MICROBIAL COLONIZATION; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; NONHUMAN; PROPIONIBACTERIUM ACNES; PSORIASIS; REVIEW; SKIN DISEASE; SKIN FLORA; STAPHYLOCOCCUS AUREUS; WOUND HEALING IMPAIRMENT; CHRONIC DISEASE; MICROBIOLOGY; MICROFLORA; SKIN; SKIN ULCER; WOUND HEALING;

EID: 84961360449     PISSN: 00048380     EISSN: 14400960     Source Type: Journal    
DOI: 10.1111/ajd.12253     Document Type: Review
Times cited : (91)

References (67)
  • 1
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science 2001; 291: 1304-1351.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 3
    • 84861992014 scopus 로고    scopus 로고
    • The application of ecological theory toward an understanding of the human microbiome
    • Costello EK, Stagaman K, Dethlefsen L, et al. The application of ecological theory toward an understanding of the human microbiome. Science 2012; 336: 1255-1262.
    • (2012) Science , vol.336 , pp. 1255-1262
    • Costello, E.K.1    Stagaman, K.2    Dethlefsen, L.3
  • 4
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy human microbiome
    • Consortium THMP,. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486: 207-214.
    • (2012) Nature , vol.486 , pp. 207-214
    • Consortium, T.1
  • 5
    • 0017341656 scopus 로고
    • Microbial ecology of the gastrointestinal tract
    • Savage DC,. Microbial ecology of the gastrointestinal tract. Annu. Rev. Microbiol. 1977; 31: 107-133.
    • (1977) Annu. Rev. Microbiol. , vol.31 , pp. 107-133
    • Savage, D.C.1
  • 6
    • 79952712983 scopus 로고    scopus 로고
    • Gut microbiome-host interactions in health and disease
    • Kinross JM, Darzi AW, Nicholson JK,. Gut microbiome-host interactions in health and disease. Genome. Med. 2011; 3: 14.
    • (2011) Genome. Med. , vol.3 , pp. 14
    • Kinross, J.M.1    Darzi, A.W.2    Nicholson, J.K.3
  • 7
    • 84858439578 scopus 로고    scopus 로고
    • The human microbiome: At the interface of health and disease
    • Cho I, Blaser MJ,. The human microbiome: at the interface of health and disease. Nat. Rev. Genet. 2012; 13: 260-270.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 260-270
    • Cho, I.1    Blaser, M.J.2
  • 8
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
    • Hsiao EY, McBride SW, Hsien S, et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 2013; 155: 1451-1463.
    • (2013) Cell , vol.155 , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3
  • 9
    • 72949091232 scopus 로고    scopus 로고
    • Bacterial community variation in human body habitats across space and time
    • Costello EK, Lauber CL, Hamady M, et al. Bacterial community variation in human body habitats across space and time. Science 2009; 326: 1694-1697.
    • (2009) Science , vol.326 , pp. 1694-1697
    • Costello, E.K.1    Lauber, C.L.2    Hamady, M.3
  • 11
    • 0016515882 scopus 로고
    • Analysis of lipid composition of isolated human sebaceous gland homogenates after incubation with cutaneous bacteria. Thin-layer chromatography
    • Puhvel SM, Reisner RM, Sakamoto M,. Analysis of lipid composition of isolated human sebaceous gland homogenates after incubation with cutaneous bacteria. Thin-layer chromatography. J. Invest. Dermatol. 1975; 64: 406-411.
    • (1975) J. Invest. Dermatol. , vol.64 , pp. 406-411
    • Puhvel, S.M.1    Reisner, R.M.2    Sakamoto, M.3
  • 12
    • 0033989564 scopus 로고    scopus 로고
    • Evolving superantigens of Staphylococcus aureus
    • Ulrich RG,. Evolving superantigens of Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 2000; 27: 1-7.
    • (2000) FEMS Immunol. Med. Microbiol. , vol.27 , pp. 1-7
    • Ulrich, R.G.1
  • 13
    • 84856940329 scopus 로고    scopus 로고
    • Skin microbiome: Looking back to move forward
    • Kong HH, Segre JA,. Skin microbiome: looking back to move forward. J. Invest. Dermatol. 2012; 132: 933-939.
    • (2012) J. Invest. Dermatol. , vol.132 , pp. 933-939
    • Kong, H.H.1    Segre, J.A.2
  • 14
    • 83755185513 scopus 로고    scopus 로고
    • Experimental and analytical tools for studying the human microbiome
    • Kuczynski J, Lauber CL, Walters WA, et al. Experimental and analytical tools for studying the human microbiome. Nat. Rev. Genet. 2012; 13: 47-58.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 47-58
    • Kuczynski, J.1    Lauber, C.L.2    Walters, W.A.3
  • 15
    • 77950904616 scopus 로고    scopus 로고
    • Forensic identification using skin bacterial communities
    • Fierer N, Lauber CL, Zhou N, et al. Forensic identification using skin bacterial communities. Proc. Natl. Acad. Sci. U.S.A. 2010; 107: 6477-6481.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 6477-6481
    • Fierer, N.1    Lauber, C.L.2    Zhou, N.3
  • 16
    • 78049502174 scopus 로고    scopus 로고
    • The bacterial microbiota in the oral mucosa of rural Amerindians
    • Contreras M, Costello EK, Hidalgo G, et al. The bacterial microbiota in the oral mucosa of rural Amerindians. Microbiology 2010; 156: 3282-3287.
    • (2010) Microbiology , vol.156 , pp. 3282-3287
    • Contreras, M.1    Costello, E.K.2    Hidalgo, G.3
  • 17
    • 84862522999 scopus 로고    scopus 로고
    • Human skin microbiota: High diversity of DNA viruses identified on the human skin by high throughput sequencing
    • Foulongne V, Sauvage V, Hebert C, et al. Human skin microbiota: high diversity of DNA viruses identified on the human skin by high throughput sequencing. PLoS ONE 2012; 7: e38499.
    • (2012) PLoS ONE , vol.7 , pp. e38499
    • Foulongne, V.1    Sauvage, V.2    Hebert, C.3
  • 18
    • 80052851309 scopus 로고    scopus 로고
    • Diversity of the human skin microbiome early in life
    • Capone KA, Dowd SE, Stamatas GN, et al. Diversity of the human skin microbiome early in life. J. Invest. Dermatol. 2011; 131: 2026-2032.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 2026-2032
    • Capone, K.A.1    Dowd, S.E.2    Stamatas, G.N.3
  • 19
    • 46449124442 scopus 로고    scopus 로고
    • A diversity profile of the human skin microbiota
    • Grice EA, Kong HH, Renaud G, et al. A diversity profile of the human skin microbiota. Genome Res. 2008; 18: 1043-1050.
    • (2008) Genome Res. , vol.18 , pp. 1043-1050
    • Grice, E.A.1    Kong, H.H.2    Renaud, G.3
  • 20
    • 84858763397 scopus 로고    scopus 로고
    • Evaluation of methods for the extraction and purification of DNA from the human microbiome
    • Yuan S, Cohen DB, Ravel J, et al. Evaluation of methods for the extraction and purification of DNA from the human microbiome. PLoS ONE 2012; 7: e33865.
    • (2012) PLoS ONE , vol.7 , pp. e33865
    • Yuan, S.1    Cohen, D.B.2    Ravel, J.3
  • 21
    • 84884470145 scopus 로고    scopus 로고
    • A new method for extracting skin microbes allows metagenomic analysis of whole-deep skin
    • Garcia-Garcerà M, Garcia-Etxebarria K, Coscollà M, et al. A new method for extracting skin microbes allows metagenomic analysis of whole-deep skin. PLoS ONE 2013; 8: e74914.
    • (2013) PLoS ONE , vol.8 , pp. e74914
    • Garcia-Garcerà, M.1    Garcia-Etxebarria, K.2    Coscollà, M.3
  • 23
    • 84856305295 scopus 로고    scopus 로고
    • Generating barcoded libraries for multiplex high-throughput sequencing
    • Knapp M, Stiller M, Meyer M,. Generating barcoded libraries for multiplex high-throughput sequencing. Methods Mol. Biol. 2012; 840: 155-170.
    • (2012) Methods Mol. Biol. , vol.840 , pp. 155-170
    • Knapp, M.1    Stiller, M.2    Meyer, M.3
  • 24
    • 35549007148 scopus 로고    scopus 로고
    • Short pyrosequencing reads suffice for accurate microbial community analysis
    • Liu Z, Lozupone C, Hamady M, et al. Short pyrosequencing reads suffice for accurate microbial community analysis. Nucleic Acids Res. 2007; 35: e120.
    • (2007) Nucleic Acids Res. , vol.35 , pp. e120
    • Liu, Z.1    Lozupone, C.2    Hamady, M.3
  • 25
    • 84878647680 scopus 로고    scopus 로고
    • Comparative metagenomic and rRNA microbial diversity characterization using archaeal and bacterial synthetic communities
    • Shakya M, Quince C, Campbell JH, et al. Comparative metagenomic and rRNA microbial diversity characterization using archaeal and bacterial synthetic communities. Environ. Microbiol. 2013; 15: 1882-1899.
    • (2013) Environ. Microbiol. , vol.15 , pp. 1882-1899
    • Shakya, M.1    Quince, C.2    Campbell, J.H.3
  • 26
    • 20244376755 scopus 로고    scopus 로고
    • Comparative metagenomics of microbial communities
    • Tringe SG, von Mering C, Kobayashi A, et al. Comparative metagenomics of microbial communities. Science 2005; 308: 554-557.
    • (2005) Science , vol.308 , pp. 554-557
    • Tringe, S.G.1    Von Mering, C.2    Kobayashi, A.3
  • 27
    • 84860756398 scopus 로고    scopus 로고
    • Performance comparison of benchtop high-throughput sequencing platforms
    • Loman NJ, Misra RV, Dallman TJ, et al. Performance comparison of benchtop high-throughput sequencing platforms. Nat. Biotechnol. 2012; 30: 434-439.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 434-439
    • Loman, N.J.1    Misra, R.V.2    Dallman, T.J.3
  • 28
    • 84865591846 scopus 로고    scopus 로고
    • A tale of three next generation sequencing platforms: Comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers
    • Quail MA, Smith M, Coupland P, et al. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers. BMC Genomics 2012; 13: 341.
    • (2012) BMC Genomics , vol.13 , pp. 341
    • Quail, M.A.1    Smith, M.2    Coupland, P.3
  • 29
    • 77952243141 scopus 로고    scopus 로고
    • QIIME allows analysis of high-throughput community sequencing data
    • Caporaso JG, Kuczynski J, Stombaugh J, et al. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods 2010; 7: 335-336.
    • (2010) Nat. Methods , vol.7 , pp. 335-336
    • Caporaso, J.G.1    Kuczynski, J.2    Stombaugh, J.3
  • 30
    • 72949107142 scopus 로고    scopus 로고
    • Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities
    • Schloss PD, Westcott SL, Ryabin T, et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl. Environ. Microbiol. 2009; 75: 7537-7541.
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 7537-7541
    • Schloss, P.D.1    Westcott, S.L.2    Ryabin, T.3
  • 31
    • 84864440400 scopus 로고    scopus 로고
    • Metagenomic microbial community profiling using unique clade-specific marker genes
    • Segata N, Waldron L, Ballarini A, et al. Metagenomic microbial community profiling using unique clade-specific marker genes. Nat. Methods 2012; 9: 811-814.
    • (2012) Nat. Methods , vol.9 , pp. 811-814
    • Segata, N.1    Waldron, L.2    Ballarini, A.3
  • 32
    • 33847702910 scopus 로고    scopus 로고
    • MEGAN analysis of metagenomic data
    • Huson DH, Auch AF, Qi J, et al. MEGAN analysis of metagenomic data. Genome Res. 2007; 17: 377-386.
    • (2007) Genome Res. , vol.17 , pp. 377-386
    • Huson, D.H.1    Auch, A.F.2    Qi, J.3
  • 34
    • 84871799128 scopus 로고    scopus 로고
    • MGAviewer: A desktop visualization tool for analysis of metagenomics alignment data
    • Zhu Z, Niu B, Chen J, et al. MGAviewer: a desktop visualization tool for analysis of metagenomics alignment data. Bioinformatics 2013; 29: 122-123.
    • (2013) Bioinformatics , vol.29 , pp. 122-123
    • Zhu, Z.1    Niu, B.2    Chen, J.3
  • 35
    • 84869066862 scopus 로고    scopus 로고
    • MetaSee: An interactive and extendable visualization toolbox for metagenomic sample analysis and comparison
    • Song B, Su X, Xu J, et al. MetaSee: an interactive and extendable visualization toolbox for metagenomic sample analysis and comparison. PLoS ONE 2012; 7: e48998.
    • (2012) PLoS ONE , vol.7 , pp. e48998
    • Song, B.1    Su, X.2    Xu, J.3
  • 36
    • 79954997196 scopus 로고    scopus 로고
    • Bioinformatics for human genetics: Promises and challenges
    • Lindblom A, Robinson PN,. Bioinformatics for human genetics: promises and challenges. Hum. Mutat. 2011; 32: 495-500.
    • (2011) Hum. Mutat. , vol.32 , pp. 495-500
    • Lindblom, A.1    Robinson, P.N.2
  • 37
    • 66349083859 scopus 로고    scopus 로고
    • Topographical and temporal diversity of the human skin microbiome
    • Grice EA, Kong HH, Conlan S, et al. Topographical and temporal diversity of the human skin microbiome. Science 2009; 324: 1190-1192.
    • (2009) Science , vol.324 , pp. 1190-1192
    • Grice, E.A.1    Kong, H.H.2    Conlan, S.3
  • 38
    • 84891590750 scopus 로고    scopus 로고
    • Microbiome assembly across multiple body sites in low-birthweight infants
    • Costello EK, Carlisle EM, Bik EM, et al. Microbiome assembly across multiple body sites in low-birthweight infants. MBio 2013; 4: e00782-13.
    • (2013) MBio , vol.4 , pp. e782-e713
    • Costello, E.K.1    Carlisle, E.M.2    Bik, E.M.3
  • 39
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • Dominguez-Bello MG, Costello EK, Contreras M, et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc. Natl. Acad. Sci. U.S.A. 2010; 107: 11971-11975.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3
  • 40
    • 0016757401 scopus 로고
    • Age-related changes in the resident bacterial flora of the human face
    • Leyden JJ, McGinley KJ, Mills OH, et al. Age-related changes in the resident bacterial flora of the human face. J. Invest. Dermatol. 1975; 65: 379-381.
    • (1975) J. Invest. Dermatol. , vol.65 , pp. 379-381
    • Leyden, J.J.1    McGinley, K.J.2    Mills, O.H.3
  • 41
    • 84877119573 scopus 로고    scopus 로고
    • Significant changes in the skin microbiome mediated by the sport of roller derby
    • Meadow JF, Bateman AC, Herkert KM, et al. Significant changes in the skin microbiome mediated by the sport of roller derby. PeerJ 2013; 1: e53.
    • (2013) PeerJ , vol.1 , pp. e53
    • Meadow, J.F.1    Bateman, A.C.2    Herkert, K.M.3
  • 42
    • 84860560056 scopus 로고    scopus 로고
    • Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis
    • Kong HH, Oh J, Deming C, et al. Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis. Genome Res. 2012; 22: 850-859.
    • (2012) Genome Res. , vol.22 , pp. 850-859
    • Kong, H.H.1    Oh, J.2    Deming, C.3
  • 43
    • 84890535921 scopus 로고    scopus 로고
    • The altered landscape of the human skin microbiome in patients with primary immunodeficiencies
    • Oh J, Freeman AF, Park M, et al. The altered landscape of the human skin microbiome in patients with primary immunodeficiencies. Genome Res. 2013; 23: 2103-2114.
    • (2013) Genome Res. , vol.23 , pp. 2103-2114
    • Oh, J.1    Freeman, A.F.2    Park, M.3
  • 44
    • 84872534085 scopus 로고    scopus 로고
    • Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease
    • Nylund L, Satokari R, Nikkilä J, et al. Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease. BMC Microbiol. 2013; 13: 12.
    • (2013) BMC Microbiol. , vol.13 , pp. 12
    • Nylund, L.1    Satokari, R.2    Nikkilä, J.3
  • 45
    • 84960990582 scopus 로고
    • Significance of infections in origin of psoriasis
    • Norrlind R,. Significance of infections in origin of psoriasis. Acta Rheumatol. Scan. 1955; 1: 135-144.
    • (1955) Acta Rheumatol. Scan. , vol.1 , pp. 135-144
    • Norrlind, R.1
  • 46
    • 84921430770 scopus 로고    scopus 로고
    • Antistreptococcal interventions for guttate and chronic plaque psoriasis
    • : CD001976
    • Owen CM, Chalmers RJ, O'Sullivan T, et al. Antistreptococcal interventions for guttate and chronic plaque psoriasis. Cochrane Database Syst. Rev. 2000; (2): CD001976.
    • (2000) Cochrane Database Syst. Rev. , Issue.2
    • Owen, C.M.1    Chalmers, R.J.2    O'Sullivan, T.3
  • 47
    • 84857060175 scopus 로고    scopus 로고
    • Comparison of bacterial microbiota in skin biopsies from normal and psoriatic skin
    • Fahlén A, Engstrand L, Baker BS, et al. Comparison of bacterial microbiota in skin biopsies from normal and psoriatic skin. Arch. Dermatol. Res. 2012; 304: 15-22.
    • (2012) Arch. Dermatol. Res. , vol.304 , pp. 15-22
    • Fahlén, A.1    Engstrand, L.2    Baker, B.S.3
  • 48
    • 84896097133 scopus 로고    scopus 로고
    • Microbiomic signatures of psoriasis: Feasibility and methodology comparison
    • Statnikov A, Alekseyenko AV, Li Z, et al. Microbiomic signatures of psoriasis: feasibility and methodology comparison. Sci. Rep. 2013; 3: 2620.
    • (2013) Sci. Rep. , vol.3 , pp. 2620
    • Statnikov, A.1    Alekseyenko, A.V.2    Li, Z.3
  • 49
    • 84994034999 scopus 로고    scopus 로고
    • Potential anti-inflammatory treatments for chronic wounds
    • McKelvey K, Xue M, Whitmont K, et al. Potential anti-inflammatory treatments for chronic wounds. Wound. Pract. Res. 2012; 20: 86-89.
    • (2012) Wound. Pract. Res. , vol.20 , pp. 86-89
    • McKelvey, K.1    Xue, M.2    Whitmont, K.3
  • 50
    • 84884413581 scopus 로고    scopus 로고
    • Propionibacterium acnes strain populations in the human skin microbiome associated with acne
    • Fitz-Gibbon S, Tomida S, Chiu B-H, et al. Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J. Invest. Dermatol. 2013; 133: 2152-2160.
    • (2013) J. Invest. Dermatol. , vol.133 , pp. 2152-2160
    • Fitz-Gibbon, S.1    Tomida, S.2    Chiu, B.-H.3
  • 51
    • 84884416060 scopus 로고    scopus 로고
    • A distinct acne microbiome: Fact or fiction?
    • Eady EA, Layton AM,. A distinct acne microbiome: fact or fiction? J. Invest. Dermatol. 2013; 133: 2294-2295.
    • (2013) J. Invest. Dermatol. , vol.133 , pp. 2294-2295
    • Eady, E.A.1    Layton, A.M.2
  • 52
  • 53
    • 68149089830 scopus 로고    scopus 로고
    • Community analysis of chronic wound bacteria using 16S rRNA gene-based pyrosequencing: Impact of diabetes and antibiotics on chronic wound microbiota
    • Price LB, Liu CM, Melendez JH, et al. Community analysis of chronic wound bacteria using 16S rRNA gene-based pyrosequencing: impact of diabetes and antibiotics on chronic wound microbiota. PLoS ONE 2009; 4: e6462.
    • (2009) PLoS ONE , vol.4 , pp. e6462
    • Price, L.B.1    Liu, C.M.2    Melendez, J.H.3
  • 54
    • 85056069363 scopus 로고    scopus 로고
    • A comparison of bacterial composition in diabetic ulcers and contralateral intact skin
    • Gontcharova V, Youn E, Sun Y, et al. A comparison of bacterial composition in diabetic ulcers and contralateral intact skin. Open Microbiol. J. 2010; 4: 8-19.
    • (2010) Open Microbiol. J. , vol.4 , pp. 8-19
    • Gontcharova, V.1    Youn, E.2    Sun, Y.3
  • 55
    • 72449120851 scopus 로고    scopus 로고
    • Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches
    • Wolcott RD, Gontcharova V, Sun Y, et al. Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches. BMC Microbiol. 2009; 9: 226.
    • (2009) BMC Microbiol. , vol.9 , pp. 226
    • Wolcott, R.D.1    Gontcharova, V.2    Sun, Y.3
  • 56
    • 79958768051 scopus 로고    scopus 로고
    • Skin microbiome: Genomics-based insights into the diversity and role of skin microbes
    • Kong HH,. Skin microbiome: genomics-based insights into the diversity and role of skin microbes. Trends Mol. Med. 2011; 17: 320-328.
    • (2011) Trends Mol. Med. , vol.17 , pp. 320-328
    • Kong, H.H.1
  • 57
    • 79951501339 scopus 로고    scopus 로고
    • Atopic dermatitis diagnostic criteria and outcome measures for clinical trials: Still a mess
    • Flohr C,. Atopic dermatitis diagnostic criteria and outcome measures for clinical trials: still a mess. J. Invest. Dermatol. 2011; 131: 557-559.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 557-559
    • Flohr, C.1
  • 60
    • 84961330598 scopus 로고    scopus 로고
    • US News World Rep. Available from URL:. (Accessed 23 Apr 2014.)
    • US News World Rep. Rate of diabetes cases doubles in 10 years: CDC. Available from URL: http://health.usnews.com/health-news/diet-fitness/diabetes/articles/2008/10/30/rate-of-diabetes-cases-doubles-in-10-years-cdc. (Accessed 23 Apr 2014.)
    • Rate of Diabetes Cases Doubles in 10 Years: CDC.
  • 61
    • 84875759214 scopus 로고    scopus 로고
    • Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and industrial revolutions
    • Adler CJ, Dobney K, Weyrich LS, et al. Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and industrial revolutions. Nat. Genet. 2013; 45: 450-455.
    • (2013) Nat. Genet. , vol.45 , pp. 450-455
    • Adler, C.J.1    Dobney, K.2    Weyrich, L.S.3
  • 62
    • 84923080032 scopus 로고    scopus 로고
    • Gut microbiome of the Hadza hunter-gatherers
    • Schnorr SL, Candela M, Rampelli S, et al. Gut microbiome of the Hadza hunter-gatherers. Nat. Commun. 2014; 5: 3654.
    • (2014) Nat. Commun. , vol.5 , pp. 3654
    • Schnorr, S.L.1    Candela, M.2    Rampelli, S.3
  • 63
    • 84873875156 scopus 로고    scopus 로고
    • Gut microbiomes of Malawian twin pairs discordant for kwashiorkor
    • Smith MI, Yatsunenko T, Manary MJ, et al. Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Science 2013; 339: 548-554.
    • (2013) Science , vol.339 , pp. 548-554
    • Smith, M.I.1    Yatsunenko, T.2    Manary, M.J.3
  • 64
    • 70449703996 scopus 로고    scopus 로고
    • What are the consequences of the disappearing human microbiota?
    • Blaser MJ, Falkow S,. What are the consequences of the disappearing human microbiota? Nat. Rev. Microbiol. 2009; 7: 887-894.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 887-894
    • Blaser, M.J.1    Falkow, S.2
  • 65
    • 84865477413 scopus 로고    scopus 로고
    • Antibiotics in early life alter the murine colonic microbiome and adiposity
    • Cho I, Yamanishi S, Cox L, et al. Antibiotics in early life alter the murine colonic microbiome and adiposity. Nature 2012; 488: 621-626.
    • (2012) Nature , vol.488 , pp. 621-626
    • Cho, I.1    Yamanishi, S.2    Cox, L.3
  • 66
    • 84873553724 scopus 로고    scopus 로고
    • Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus
    • Shu M, Wang Y, Yu J, et al. Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus. PLoS ONE 2013; 8: e55380.
    • (2013) PLoS ONE , vol.8 , pp. e55380
    • Shu, M.1    Wang, Y.2    Yu, J.3
  • 67
    • 0018039648 scopus 로고
    • Quantitative studies on competitive activities of skin bacteria growing on solid media
    • Milyani RM, Selwyn S,. Quantitative studies on competitive activities of skin bacteria growing on solid media. J. Med. Microbiol. 1978; 11: 379-386.
    • (1978) J. Med. Microbiol. , vol.11 , pp. 379-386
    • Milyani, R.M.1    Selwyn, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.