Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 13, 2015, Pages 4003-4008

  Zhang, Lianjun ^a,b   Chen, Min ^a   Wen, Qing ^a,b   Li, Yaqiong ^a,b   Wang, Yaqing ^c   Wang, Yanbo ^a,b   Qin, Yan ^a,b   Cui, Xiuhong ^a   Yang, Lin ^c   Huff, Vicki ^d,e   Gao, Fei ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

Leydig cells; Sertoli cells; Transdifferentiation; Wt1; catenin

Indexed keywords

WT1 PROTEIN; BETA CATENIN; CTNNB1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENE DELETION; GENE EXPRESSION; GENETIC REGULATION; LEYDIG CELL; MALE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; SERTOLI CELL; TESTIS DEVELOPMENT; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; METABOLISM; TESTIS;

ANIMALS; BETA CATENIN; CELL DIFFERENTIATION; CELL LINEAGE; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; LEYDIG CELLS; MALE; MICE, KNOCKOUT; SERTOLI CELLS; TESTIS; WT1 PROTEINS;

EID: 84961292203     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1422371112     Document Type: Article

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