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Volumn 212, Issue 6, 2016, Pages 517-523

Nuclear unphosphorylated STAT3 correlates with a worse prognosis in human glioblastoma

Author keywords

Glioblastoma; Glioma; Immunohistochemistry; STAT3; u STAT3

Indexed keywords

STAT3 PROTEIN;

EID: 84961267176     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2016.03.001     Document Type: Article
Times cited : (12)

References (30)
  • 1
    • 57849109837 scopus 로고    scopus 로고
    • Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
    • [1] Alcantara Llaguno, S., Chen, J., Kwon, C.H., et al. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 15 (2009), 45–56.
    • (2009) Cancer Cell , vol.15 , pp. 45-56
    • Alcantara Llaguno, S.1    Chen, J.2    Kwon, C.H.3
  • 2
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • [2] Louis, D.N., Ohgaki, H., Wiestler, O.D., et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114 (2007), 97–109.
    • (2007) Acta Neuropathol. , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 3
    • 67349204309 scopus 로고    scopus 로고
    • Histopathologic predictors of pilocytic astrocytoma event-free survival
    • [3] Tibbetts, K.M., Emnett, R.J., Gao, F., et al. Histopathologic predictors of pilocytic astrocytoma event-free survival. Acta Neuropathol. 117 (2009), 657–665.
    • (2009) Acta Neuropathol. , vol.117 , pp. 657-665
    • Tibbetts, K.M.1    Emnett, R.J.2    Gao, F.3
  • 4
    • 84886009591 scopus 로고    scopus 로고
    • CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010
    • [4] Ostrom, Q.T., Gittleman, H., Farah, P., et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010. Neuro. Oncol. 15:Suppl. 2 (2013), 1–56.
    • (2013) Neuro. Oncol. , vol.15 , pp. 1-56
    • Ostrom, Q.T.1    Gittleman, H.2    Farah, P.3
  • 5
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • [5] Stupp, R., Mason, W.P., van den Bent, M.J., et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352 (2005), 987–996.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 6
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORT C-NCIC trial
    • [6] Stupp, R., Hegi, M.E., Mason, W.P., et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORT C-NCIC trial. Lancet Oncol., 2009, 459–466.
    • (2009) Lancet Oncol. , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 7
    • 84939638314 scopus 로고    scopus 로고
    • Nonsurgical treatment of recurrent glioblastoma
    • [7] Gallego, O., Nonsurgical treatment of recurrent glioblastoma. Curr. Oncol. 22 (2015), 273–281.
    • (2015) Curr. Oncol. , vol.22 , pp. 273-281
    • Gallego, O.1
  • 8
    • 84898909914 scopus 로고    scopus 로고
    • Transcription factor STAT3 as a novel molecular target for cancer prevention
    • [8] Xiong, A., Yang, Z., Shen, Y., et al. Transcription factor STAT3 as a novel molecular target for cancer prevention. Cancers 6 (2014), 926–957.
    • (2014) Cancers , vol.6 , pp. 926-957
    • Xiong, A.1    Yang, Z.2    Shen, Y.3
  • 10
    • 84860014863 scopus 로고    scopus 로고
    • Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA
    • [10] Timofeeva, O.A., Chasovskikh, S., Lonskaya, I., et al. Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA. J. Biol. Chem. 287 (2012), 14192–14200.
    • (2012) J. Biol. Chem. , vol.287 , pp. 14192-14200
    • Timofeeva, O.A.1    Chasovskikh, S.2    Lonskaya, I.3
  • 11
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • [11] Wen, Z., Zhong, Z., Darnell, J.E., Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82 (1995), 241–250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell, J.E.3
  • 12
    • 84955677188 scopus 로고    scopus 로고
    • STAT3 serine 727 phosphorylation: a relevant target to radiosensitize human glioblastoma
    • [12] Ouédraogo, Z.G., Müller-Barthélémy, M., Kemeny, J.L., et al. STAT3 serine 727 phosphorylation: a relevant target to radiosensitize human glioblastoma. Brain Pathol. 26 (2015), 18–30.
    • (2015) Brain Pathol. , vol.26 , pp. 18-30
    • Ouédraogo, Z.G.1    Müller-Barthélémy, M.2    Kemeny, J.L.3
  • 13
    • 84867548761 scopus 로고    scopus 로고
    • STAT signaling in glioma cells
    • [13] Swiatek-Machado, K., Kaminska, B., STAT signaling in glioma cells. Glioma Signal 986 (2013), 189–208.
    • (2013) Glioma Signal , vol.986 , pp. 189-208
    • Swiatek-Machado, K.1    Kaminska, B.2
  • 14
    • 84871336215 scopus 로고    scopus 로고
    • The role of STAT3 activation in modulating the immune microenvironment of GBM
    • [14] See, A.P., Han, J.E., Phallen, J., et al. The role of STAT3 activation in modulating the immune microenvironment of GBM. J. Neurooncol. 110 (2012), 359–368.
    • (2012) J. Neurooncol. , vol.110 , pp. 359-368
    • See, A.P.1    Han, J.E.2    Phallen, J.3
  • 15
    • 64849111865 scopus 로고    scopus 로고
    • Targeting STAT3 in cancer: how successful are we?
    • [15] Yue, P., Turkson, J., Targeting STAT3 in cancer: how successful are we?. Expert Opin. Investig. Drugs 18 (2009), 45–56.
    • (2009) Expert Opin. Investig. Drugs , vol.18 , pp. 45-56
    • Yue, P.1    Turkson, J.2
  • 16
    • 84916883583 scopus 로고    scopus 로고
    • Targeting MET for glioma therapy
    • [16] Awad, A.J., Burns, T.C., Zhang, Y., et al. Targeting MET for glioma therapy. Neurosurg. Focus 37 (2014), 1–7.
    • (2014) Neurosurg. Focus , vol.37 , pp. 1-7
    • Awad, A.J.1    Burns, T.C.2    Zhang, Y.3
  • 18
    • 84870901484 scopus 로고    scopus 로고
    • Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity
    • [18] Shen, S., Niso-Santano, M.A.S., Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity. PubMed Commons. Mol. Cell. 48 (2014), 667–680.
    • (2014) PubMed Commons. Mol. Cell. , vol.48 , pp. 667-680
    • Shen, S.1    Niso-Santano, M.A.S.2
  • 19
    • 84860213684 scopus 로고    scopus 로고
    • The value of a tumor bank in the development of cancer research in Brazil: 13 years of experience at the AC camargo hospital
    • [19] Campos, A.H., Silva, A.A., Mota, L.D., et al. The value of a tumor bank in the development of cancer research in Brazil: 13 years of experience at the AC camargo hospital. Biopreserv. Biobank. 10 (2012), 168–173.
    • (2012) Biopreserv. Biobank. , vol.10 , pp. 168-173
    • Campos, A.H.1    Silva, A.A.2    Mota, L.D.3
  • 20
    • 84934945282 scopus 로고    scopus 로고
    • Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival
    • [20] Lopes, M.H., Santos, T.G., Rodrigues, B.R., et al. Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival. Oncogene 34 (2015), 3305–3314.
    • (2015) Oncogene , vol.34 , pp. 3305-3314
    • Lopes, M.H.1    Santos, T.G.2    Rodrigues, B.R.3
  • 21
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • [21] Kononen, J., Bubendorf, L., Kallioniemi, A., et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat. Med. 4 (1998), 844–847.
    • (1998) Nat. Med. , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 22
    • 84878939129 scopus 로고    scopus 로고
    • A comparison between manual and automated evaluations of tissue microarray patterns of protein expression
    • [22] Alvarenga, A.W., Coutinho-Camillo, C.M., Rodrigues, B.R., et al. A comparison between manual and automated evaluations of tissue microarray patterns of protein expression. J. Histochem. Cytochem. 61 (2013), 272–282.
    • (2013) J. Histochem. Cytochem. , vol.61 , pp. 272-282
    • Alvarenga, A.W.1    Coutinho-Camillo, C.M.2    Rodrigues, B.R.3
  • 23
    • 73649123907 scopus 로고    scopus 로고
    • An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1
    • [23] Verhaak, R.G.W., Hoadley, K.A., Purdom, E., et al. An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1. Cancer Cell, 17, 2010, 98.
    • (2010) Cancer Cell , vol.17 , pp. 98
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3
  • 24
    • 13444309088 scopus 로고    scopus 로고
    • Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation
    • [24] Yang, J., Chatterjee-kishore, M., Staugaitis, S.M., et al. Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation. Cancer Res. 65 (2005), 939–947.
    • (2005) Cancer Res. , vol.65 , pp. 939-947
    • Yang, J.1    Chatterjee-kishore, M.2    Staugaitis, S.M.3
  • 25
    • 34848824363 scopus 로고    scopus 로고
    • Long-term survival with glioblastoma multiforme
    • [25] Krex, D., Klink, B., Hartmann, C., et al. Long-term survival with glioblastoma multiforme. Brain 130 (2007), 2596–2606.
    • (2007) Brain , vol.130 , pp. 2596-2606
    • Krex, D.1    Klink, B.2    Hartmann, C.3
  • 26
    • 78449312044 scopus 로고    scopus 로고
    • STAT3 tyrosine phosphorylation influences survival in glioblastoma
    • [26] Birner, P., Toumangelova-Uzeir, K., Natchev, S., et al. STAT3 tyrosine phosphorylation influences survival in glioblastoma. J. Neurooncol. 100 (2010), 339–343.
    • (2010) J. Neurooncol. , vol.100 , pp. 339-343
    • Birner, P.1    Toumangelova-Uzeir, K.2    Natchev, S.3
  • 27
    • 84898777523 scopus 로고    scopus 로고
    • STAT3 Tyr705 phosphorylation affects clinical outcome in patients with newly diagnosed supratentorial glioblastoma
    • [27] Lin, G.S., Yang, L.J., Wang, X.F., et al. STAT3 Tyr705 phosphorylation affects clinical outcome in patients with newly diagnosed supratentorial glioblastoma. Med. Oncol., 31, 2014, 924.
    • (2014) Med. Oncol. , vol.31 , pp. 924
    • Lin, G.S.1    Yang, L.J.2    Wang, X.F.3
  • 28
    • 84887042313 scopus 로고    scopus 로고
    • Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1
    • [28] Soares, I.N., Caetano, F.A., Pinder, J., et al. Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1. Mol. Cell. Proteomics 12 (2013), 3253–3270.
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 3253-3270
    • Soares, I.N.1    Caetano, F.A.2    Pinder, J.3
  • 29
    • 0142152429 scopus 로고    scopus 로고
    • PIAS proteins promote SUMO-1 conjugation to STAT1
    • [29] Ungureanu, D., Vanhatupa, S., Kotaja, N., et al. PIAS proteins promote SUMO-1 conjugation to STAT1. Blood 102 (2003), 3311–3313.
    • (2003) Blood , vol.102 , pp. 3311-3313
    • Ungureanu, D.1    Vanhatupa, S.2    Kotaja, N.3
  • 30
    • 84991208336 scopus 로고    scopus 로고
    • National Institute of Health A Phase I Trial of WP1066. In: ClinicalTrials.gov (Internet). Bethesda (MD): National Library of Medicine (US); NLM Identifier: NCT01904123.
    • [30] MD Anderson Cancer Center; National Institute of Health (2014). A Phase I Trial of WP1066. In: ClinicalTrials.gov (Internet). Bethesda (MD): National Library of Medicine (US); https:clinicaltrials.gov/ct2/show/NCT01904123 NLM Identifier: NCT01904123.
    • (2014)


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