A comparison between manual and automated evaluations of tissue microarray patterns of protein expression

Journal of Histochemistry and Cytochemistry

Volumn 61, Issue 4, 2013, Pages 272-282

  Alvarenga, Arthur W ^a   Coutinho Camillo, Claudia M ^a   Rodrigues, Bruna R ^a   Rocha, Rafael M ^a   Torres, Luiz Fernando B ^b   Martins, Vilma R ^a   da Cunha, Isabela W ^a   Hajj, Glaucia N M ^a  

^a A C CAMARGO CANCER CENTER   (Brazil)

^b Institute Pelé Pequeno Príncipe   (Brazil)

Author keywords

Automated analysis; Immunohistochemistry; Tissue microarray

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOMATION; CARCINOGENESIS; CELL NUCLEUS; CLINICAL ARTICLE; CLINICAL EVALUATION; COMPARATIVE STUDY; CORRELATION ANALYSIS; CYTOPLASM; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RELIABILITY; REPRODUCIBILITY; TISSUE MICROARRAY; BIOSYNTHESIS; IMMUNOHISTOCHEMISTRY; METABOLISM; PHOSPHORYLATION;

AUTOMATION; HUMANS; IMMUNOHISTOCHEMISTRY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TISSUE ARRAY ANALYSIS; TOR SERINE-THREONINE KINASES;

MLCS; MLOWN;

EID: 84878939129     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155413477661     Document Type: Article

References (26)

1. Allred D.C., Harvey JM, Berardo M, Clark GM. 1998. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol. 11(2):155-168.
2. Choudhury K.R., Yagle KJ, Swanson PE, Krohn KA, Rajendran JG. 2010. A robust automated measure of average antibody staining in immunohistochemistry images. J Histochem Cytochem. 58(2):95-107.
3. Cregger M., Berger AJ, Rimm DL. 2006. Immunohistochemistry and quantitative analysis of protein expression. Arch Pathol Lab Med. 130(7):1026-1030.
4. Dancey J. 2010. mTOR signaling and drug development in cancer. Nat Rev Clin Oncol. 7(4):209-219.
5. Dhir R. 2008. Tissue microarrays: an overview. Methods Mol Biol. 441:91-103.
6. Harrington A.M., Hari P, Kroft SH. 2009. Utility of CD56 immunohistochemical studies in follow-up of plasma cell myeloma. Am J Clin Pathol. 132(1):60-66.
7. Hatanaka Y., Hashizume K, Nitta K, Kato T, Itoh I, Tani Y. 2003. Cytometrical image analysis for immunohistochemical hormone receptor status in breast carcinomas. Pathol Int. 53(10):693-699.
8. Hirashima K., Baba Y, Watanabe M, Karashima R, Sato N, Imamura Y, Hiyoshi Y, Nagai Y, Hayashi N, Iyama K, et al. 2010. Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma. Ann Surg Oncol. 17(9):2486-2493.
9. Jara-Lazaro AR, Thamboo TP, Teh M, Tan PH. 2010. Digital pathology: exploring its applications in diagnostic surgical pathology practice. Pathology. 42(6):512-518.
10. Jawhar NM. 2009. Tissue microarray: a rapidly evolving diagnostic and research tool. Ann Saudi Med. 29(2):123-127.
11. Kayser K. 2012. Introduction of virtual microscopy in routine surgical pathology-a hypothesis and personal view from Europe. Diagn Pathol. 7:48.
12. Kim M.K., Kim TJ, Sung CO, Choi CH, Lee JW, Kim BG, Bae DS. 2010. High expression of mTOR is associated with radiation resistance in cervical cancer. J Gynecol Oncol. 21(3):181-185.
13. Kldiashvili E., Schrader T. 2011. Reproducibility of telecytology diagnosis of cervical smears in a quality assurance program: the Georgian experience. Telemed J E Health. 17(7):565-568.
14. Korkolopoulou P., Levidou G, El-Habr EA, Piperi C, Adamopoulos C, Samaras V, Boviatsis E, Thymara I, Trigka EA, Sakellariou S, et al. 2012. Phosphorylated 4E-binding protein 1 (p-4E-BP1): a novel prognostic marker in human astrocytomas. Histopathology. 61(2):293-305.
15. Krupinski E.A., Silverstein LD, Hashmi SF, Graham AR, Weinstein RS, Roehrig H. 2012. Observer performance using virtual pathology slides: impact of LCD color reproduction accuracy. J Digit Imaging. 25(6):738-743.
16. Kundel H.L., Polansky M. 2003. Measurement of observer agreement. Radiology. 228(2):303-308.
17. Landis J.R., Koch GG. 1977. The measurement of observer agreement for categorical data. Biometrics. 33(1):159-174.
18. Laurinaviciene A., Dasevicius D, Ostapenko V, Jarmalaite S, Lazutka J., Laurinavicius A. 2011. Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays. Diagn Pathol. 6:87.
19. Laurinavicius A., Laurinaviciene A, Ostapenko V, Dasevicius D, Jarmalaite S., Lazutka J. 2012. Immunohistochemistry profiles of breast ductal carcinoma: factor analysis of digital image analysis data. Diagn Pathol. 7:27.
20. McCarty KS Jr, Szabo E, Flowers JL, Cox EB, Leight GS, Miller L, Konrath J, Soper JT, Budwit DA, Creasman WT. 1986. Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors. Cancer Res. 46(8, Suppl):4244s-4248s.
21. Nap M., Teunissen R, Pieters M. 2012. A travel report of the implementation of virtual whole slide images in routine surgical pathology. APMIS. 120(4):290-297.
22. Ong C.W., Kim LG, Kong HH, Low LY, Wang TT, Supriya S, Kathiresan M., Soong R, Salto-Tellez M. 2010. Computerassisted pathological immunohistochemistry scoring is more time-effective than conventional scoring, but provides no analytical advantage. Histopathology. 56(4):523-529.
23. R Core Team. 2012. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.
24. Rojo M.G., Bueno G, Slodkowska J. 2009. Review of imaging solutions for integrated quantitative immunohistochemistry in the pathology daily practice. Folia Histochem Cytobiol. 47(3):349-354.
25. Sabatini DM. 2006. mTOR and cancer: insights into a complex relationship. Nat Rev Cancer. 6(9):729-734.
26. van Schaik FD, Oldenburg B, Offerhaus GJ, Schipper ME, Vleggaar FP, Siersema PD, van Oijen MG, Ten Kate FJ. 2012. Role of immunohistochemical markers in predicting progression of dysplasia to advanced neoplasia in patients with ulcerative colitis. Inflamm Bowel Dis. 18(3):480-488.