-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
COI: 1:CAS:528:DC%2BC3cXhtlWhs7fO, PID: 21351269
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127(12):2893–2917
-
(2010)
Int J Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
84555218419
-
Cancer immunotherapy comes of age
-
COI: 1:CAS:528:DC%2BC38Xhslygs7k%3D, PID: 22042955
-
Topalian SL, Weiner GJ, Pardoll DM (2011) Cancer immunotherapy comes of age. J Clin Oncol 29(36):4828–4836. doi:10.1200/jco.2011.38.0899
-
(2011)
J Clin Oncol
, vol.29
, Issue.36
, pp. 4828-4836
-
-
Topalian, S.L.1
Weiner, G.J.2
Pardoll, D.M.3
-
3
-
-
33646804507
-
Mechanisms of immune evasion by tumors
-
COI: 1:CAS:528:DC%2BD1cXhsVCjur4%3D, PID: 16730261
-
Drake CG, Jaffee E, Pardoll DM (2006) Mechanisms of immune evasion by tumors. Adv Immunol 90:51–81. doi:10.1016/s0065-2776(06)90002-9
-
(2006)
Adv Immunol
, vol.90
, pp. 51-81
-
-
Drake, C.G.1
Jaffee, E.2
Pardoll, D.M.3
-
4
-
-
84255197842
-
Cancer immunotherapy comes of age
-
COI: 1:CAS:528:DC%2BC3MXhs1GksLjO, PID: 22193102
-
Mellman I, Coukos G, Dranoff G (2011) Cancer immunotherapy comes of age. Nature 480(7378):480–489. doi:10.1038/nature10673
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
5
-
-
84871532643
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial
-
COI: 1:STN:280:DC%2BC38fltFGrtw%3D%3D, PID: 22858559
-
Reck M, Bondarenko I, Luft A, Serwatowski P, Barlesi F, Chacko R, Sebastian M, Lu H, Cuillerot JM, Lynch TJ (2013) Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial. Ann Oncol 24(1):75–83. doi:10.1093/annonc/mds213
-
(2013)
Ann Oncol
, vol.24
, Issue.1
, pp. 75-83
-
-
Reck, M.1
Bondarenko, I.2
Luft, A.3
Serwatowski, P.4
Barlesi, F.5
Chacko, R.6
Sebastian, M.7
Lu, H.8
Cuillerot, J.M.9
Lynch, T.J.10
-
6
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
COI: 1:CAS:528:DC%2BC3cXhtVCrtrbN, PID: 20525992
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbe C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ (2010) Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363(8):711–723. doi:10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
van den Eertwegh, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbe, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
7
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas A, Kefford R, Marshall MA, Punt CJA, Haanen JB, Marmol M, Garbe C, Gogas H, Schachter J, Linette G, Lorigan P, Kendra KL, Maio M, Trefzer U, Smylie M, McArthur GA, Dreno B, Nathan PD, Mackiewicz J, Kirkwood JM, Gomez-Navarro J, Huang B, Pavlov D, Hauschild A (2013) Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol (Meeting Abstracts) 31 (5):616–622. doi:10.1200/jco.2012.44.6112
-
(2013)
J Clin Oncol (Meeting Abstracts)
, vol.31
, Issue.5
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.A.4
Haanen, J.B.5
Marmol, M.6
Garbe, C.7
Gogas, H.8
Schachter, J.9
Linette, G.10
Lorigan, P.11
Kendra, K.L.12
Maio, M.13
Trefzer, U.14
Smylie, M.15
McArthur, G.A.16
Dreno, B.17
Nathan, P.D.18
Mackiewicz, J.19
Kirkwood, J.M.20
Gomez-Navarro, J.21
Huang, B.22
Pavlov, D.23
Hauschild, A.24
more..
-
8
-
-
76749084659
-
Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinum-based therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC)
-
Zatloukal P, Heo DS, Park K, Kang J, Butts C, Bradford D, Graziano S, Huang B, Healey D (2009) Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinum-based therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC). J Clin Oncol (Meeting Abstracts) 27 (15S):8071
-
(2009)
J Clin Oncol (Meeting Abstracts)
, vol.27
, Issue.15S
, pp. 8071
-
-
Zatloukal, P.1
Heo, D.S.2
Park, K.3
Kang, J.4
Butts, C.5
Bradford, D.6
Graziano, S.7
Huang, B.8
Healey, D.9
-
9
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
COI: 1:CAS:528:DC%2BD2MXhtVKgtb3L, PID: 16087944
-
Attia P, Phan GQ, Maker AV, Robinson MR, Quezado MM, Yang JC, Sherry RM, Topalian SL, Kammula US, Royal RE, Restifo NP, Haworth LR, Levy C, Mavroukakis SA, Nichol G, Yellin MJ, Rosenberg SA (2005) Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 23(25):6043–6053. doi:10.1200/jco.2005.06.205
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
Robinson, M.R.4
Quezado, M.M.5
Yang, J.C.6
Sherry, R.M.7
Topalian, S.L.8
Kammula, U.S.9
Royal, R.E.10
Restifo, N.P.11
Haworth, L.R.12
Levy, C.13
Mavroukakis, S.A.14
Nichol, G.15
Yellin, M.J.16
Rosenberg, S.A.17
-
10
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
COI: 1:CAS:528:DyaK3sXkslShtbs%3D, PID: 1396582
-
Ishida Y, Agata Y, Shibahara K, Honjo T (1992) Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. Embo J 11(11):3887–3895
-
(1992)
Embo J
, vol.11
, Issue.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
11
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
COI: 1:CAS:528:DC%2BD3cXntFSlt7o%3D, PID: 11015443
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 192(7):1027–1034
-
(2000)
J Exp Med
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
12
-
-
33645846313
-
Tissue expression of PD-L1 mediates peripheral T cell tolerance
-
COI: 1:CAS:528:DC%2BD28Xjsl2is78%3D, PID: 16606670
-
Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, Koulmanda M, Freeman GJ, Sayegh MH, Sharpe AH (2006) Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 203(4):883–895. doi:10.1084/jem.20051776
-
(2006)
J Exp Med
, vol.203
, Issue.4
, pp. 883-895
-
-
Keir, M.E.1
Liang, S.C.2
Guleria, I.3
Latchman, Y.E.4
Qipo, A.5
Albacker, L.A.6
Koulmanda, M.7
Freeman, G.J.8
Sayegh, M.H.9
Sharpe, A.H.10
-
13
-
-
80052476869
-
High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation
-
COI: 1:CAS:528:DC%2BC3MXhtVWqtLzJ, PID: 20373055
-
Mu CY, Huang JA, Chen Y, Chen C, Zhang XG (2011) High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation. Med Oncol 28(3):682–688. doi:10.1007/s12032-010-9515-2
-
(2011)
Med Oncol
, vol.28
, Issue.3
, pp. 682-688
-
-
Mu, C.Y.1
Huang, J.A.2
Chen, Y.3
Chen, C.4
Zhang, X.G.5
-
14
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
COI: 1:CAS:528:DC%2BC38XhtV2rsbnJ, PID: 22658128
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, Martins R, Eaton K, Chen S, Salay TM, Alaparthy S, Grosso JF, Korman AJ, Parker SM, Agrawal S, Goldberg SM, Pardoll DM, Gupta A, Wigginton JM (2012) Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 366(26):2455–2465. doi:10.1056/NEJMoa1200694
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
Pitot, H.C.11
Hamid, O.12
Bhatia, S.13
Martins, R.14
Eaton, K.15
Chen, S.16
Salay, T.M.17
Alaparthy, S.18
Grosso, J.F.19
Korman, A.J.20
Parker, S.M.21
Agrawal, S.22
Goldberg, S.M.23
Pardoll, D.M.24
Gupta, A.25
Wigginton, J.M.26
more..
-
15
-
-
84924901863
-
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial
-
COI: 1:CAS:528:DC%2BC2MXjtFShs7s%3D, PID: 25704439
-
Rizvi NA, Mazieres J, Planchard D, Stinchcombe TE, Dy GK, Antonia SJ, Horn L, Lena H, Minenza E, Mennecier B, Otterson GA, Campos LT, Gandara DR, Levy BP, Nair SG, Zalcman G, Wolf J, Souquet PJ, Baldini E, Cappuzzo F, Chouaid C, Dowlati A, Sanborn R, Lopez-Chavez A, Grohe C, Huber RM, Harbison CT, Baudelet C, Lestini BJ, Ramalingam SS (2015) Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol 16(3):257–265. doi:10.1016/s1470-2045(15)70054-9
-
(2015)
Lancet Oncol
, vol.16
, Issue.3
, pp. 257-265
-
-
Rizvi, N.A.1
Mazieres, J.2
Planchard, D.3
Stinchcombe, T.E.4
Dy, G.K.5
Antonia, S.J.6
Horn, L.7
Lena, H.8
Minenza, E.9
Mennecier, B.10
Otterson, G.A.11
Campos, L.T.12
Gandara, D.R.13
Levy, B.P.14
Nair, S.G.15
Zalcman, G.16
Wolf, J.17
Souquet, P.J.18
Baldini, E.19
Cappuzzo, F.20
Chouaid, C.21
Dowlati, A.22
Sanborn, R.23
Lopez-Chavez, A.24
Grohe, C.25
Huber, R.M.26
Harbison, C.T.27
Baudelet, C.28
Lestini, B.J.29
Ramalingam, S.S.30
more..
-
16
-
-
84965172124
-
The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses
-
University of Ottawa, Canada
-
Wells G, Shea B, O’Connell D, Petersen J, Welch V, Losos M, Tugwell P (2011) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. Department of Epidemiology and Community Medicine, University of Ottawa, Canada. http://www.ohrica/programs/clinical_epidemiology/oxfordasp
-
(2011)
Department of Epidemiology and Community Medicine
-
-
Wells, G.1
Shea, B.2
O’Connell, D.3
Petersen, J.4
Welch, V.5
Losos, M.6
Tugwell, P.7
-
17
-
-
84961235277
-
-
Spira AI, Park K, Mazieres J, Vansteenkiste JF, Rittmeyer A, Ballinger M, Waterkamp D, Kowanetz M, Mokatrin A, Fehrenbacher L Efficacy, safety and predictive biomarker results from a randomized phase II study comparing MPDL3280A vs docetaxel in 2 L/3 L NSCLC (POPLAR). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8010
-
Spira AI, Park K, Mazieres J, Vansteenkiste JF, Rittmeyer A, Ballinger M, Waterkamp D, Kowanetz M, Mokatrin A, Fehrenbacher L Efficacy, safety and predictive biomarker results from a randomized phase II study comparing MPDL3280A vs docetaxel in 2 L/3 L NSCLC (POPLAR). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8010
-
-
-
-
18
-
-
84961235278
-
-
Spigel DR, Chaft JE, Gettinger SN, Chao BH, Dirix LY, Schmid P, Chow LQM, Chappey C, Kowanetz M, Sandler A Clinical activity and safety from a phase II study (FIR) of MPDL3280A (anti-PDL1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8028
-
Spigel DR, Chaft JE, Gettinger SN, Chao BH, Dirix LY, Schmid P, Chow LQM, Chappey C, Kowanetz M, Sandler A Clinical activity and safety from a phase II study (FIR) of MPDL3280A (anti-PDL1) in PD-L1-selected patients with non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8028
-
-
-
-
19
-
-
84961235279
-
-
Paz-Ares L, Horn L, Borghaei H, Spigel DR, Steins M, Ready N, Chow LQM, Vokes EE, Felip E, Holgado E Phase III, randomized trial (CheckMate 057) of nivolumab (NIVO) versus docetaxel (DOC) in advanced non-squamous cell (non-SQ) non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p LBA109
-
Paz-Ares L, Horn L, Borghaei H, Spigel DR, Steins M, Ready N, Chow LQM, Vokes EE, Felip E, Holgado E Phase III, randomized trial (CheckMate 057) of nivolumab (NIVO) versus docetaxel (DOC) in advanced non-squamous cell (non-SQ) non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p LBA109
-
-
-
-
20
-
-
84961235280
-
-
Patnaik A, Socinski MA, Gubens MA, Gandhi L, Stevenson J, Bachman RD, Bourque J, Yang Ge J, Im E, Gadgeel SM Phase 1 study of pembrolizumab (pembro; MK-3475) plus ipilimumab (IPI) as second-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 cohort D. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8011
-
Patnaik A, Socinski MA, Gubens MA, Gandhi L, Stevenson J, Bachman RD, Bourque J, Yang Ge J, Im E, Gadgeel SM Phase 1 study of pembrolizumab (pembro; MK-3475) plus ipilimumab (IPI) as second-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 cohort D. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8011
-
-
-
-
21
-
-
84961235281
-
-
Papadimitrakopoulou V, Patnaik A, Borghaei H, Stevenson J, Gandhi L, Gubens MA, Yang JC-H, Sequist LV, Yang Ge J, Bourque J Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 Cohorts A and C. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8031
-
Papadimitrakopoulou V, Patnaik A, Borghaei H, Stevenson J, Gandhi L, Gubens MA, Yang JC-H, Sequist LV, Yang Ge J, Bourque J Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 Cohorts A and C. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8031
-
-
-
-
22
-
-
84961235282
-
-
Nishio M, Hida T, Nakagawa K, Sakai H, Nogami N, Atagi S, Takahashi T, Nokihara H, Saka H, Takenoyama M Phase II studies of nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced squamous (sq) or nonsquamous (non-sq) non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8027
-
Nishio M, Hida T, Nakagawa K, Sakai H, Nogami N, Atagi S, Takahashi T, Nokihara H, Saka H, Takenoyama M Phase II studies of nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced squamous (sq) or nonsquamous (non-sq) non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8027
-
-
-
-
23
-
-
84961235283
-
-
Liu SV, Powderly JD, Camidge DR, Ready N, Heist RS, Hodi FS, Giaccone G, Liu B, Wallin J, Funke RP Safety and efficacy of MPDL3280A (anti-PDL1) in combination with platinum-based doublet chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8030
-
Liu SV, Powderly JD, Camidge DR, Ready N, Heist RS, Hodi FS, Giaccone G, Liu B, Wallin J, Funke RP Safety and efficacy of MPDL3280A (anti-PDL1) in combination with platinum-based doublet chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8030
-
-
-
-
24
-
-
84961235284
-
-
Horn L, Spigel DR, Gettinger SN, Antonia SJ, Gordon MS, Herbst RS, Sequist LV, Chappey C, Kowanetz M, Sandler A Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PDL1) in non-small cell lung cancer (NSCLC): update from a phase Ia study. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8029
-
Horn L, Spigel DR, Gettinger SN, Antonia SJ, Gordon MS, Herbst RS, Sequist LV, Chappey C, Kowanetz M, Sandler A Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PDL1) in non-small cell lung cancer (NSCLC): update from a phase Ia study. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8029
-
-
-
-
25
-
-
84936749833
-
Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced Non-small-cell lung cancer
-
PID: 25897158
-
Gettinger SN, Horn L, Gandhi L, Spigel DR, Antonia SJ, Rizvi NA, Powderly JD, Heist RS, Carvajal RD, Jackman DM, Sequist LV, Smith DC, Leming P, Carbone DP, Pinder-Schenck MC, Topalian SL, Hodi FS, Sosman JA, Sznol M, McDermott DF, Pardoll DM, Sankar V, Ahlers CM, Salvati M, Wigginton JM, Hellmann MD, Kollia GD, Gupta AK, Brahmer JR (2015) Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced Non-small-cell lung cancer. J Clin Oncol. doi:10.1200/jco.2014.58.3708
-
(2015)
J Clin Oncol
-
-
Gettinger, S.N.1
Horn, L.2
Gandhi, L.3
Spigel, D.R.4
Antonia, S.J.5
Rizvi, N.A.6
Powderly, J.D.7
Heist, R.S.8
Carvajal, R.D.9
Jackman, D.M.10
Sequist, L.V.11
Smith, D.C.12
Leming, P.13
Carbone, D.P.14
Pinder-Schenck, M.C.15
Topalian, S.L.16
Hodi, F.S.17
Sosman, J.A.18
Sznol, M.19
McDermott, D.F.20
Pardoll, D.M.21
Sankar, V.22
Ahlers, C.M.23
Salvati, M.24
Wigginton, J.M.25
Hellmann, M.D.26
Kollia, G.D.27
Gupta, A.K.28
Brahmer, J.R.29
more..
-
26
-
-
84961235285
-
-
Gettinger SN, Hellmann MD, Shepherd FA, Antonia SJ, Brahmer JR, Chow LQM, Goldman JW, Juergens RA, Borghaei H, Ready N First-line monotherapy with nivolumab (NIVO; anti-programmed death-1 [PD-1]) in advanced non-small cell lung cancer (NSCLC): Safety, efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8025
-
Gettinger SN, Hellmann MD, Shepherd FA, Antonia SJ, Brahmer JR, Chow LQM, Goldman JW, Juergens RA, Borghaei H, Ready N First-line monotherapy with nivolumab (NIVO; anti-programmed death-1 [PD-1]) in advanced non-small cell lung cancer (NSCLC): Safety, efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 8025
-
-
-
-
27
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
PID: 25891174
-
Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, Carcereny E, Ahn MJ, Felip E, Lee JS, Hellmann MD, Hamid O, Goldman JW, Soria JC, Dolled-Filhart M, Rutledge RZ, Zhang J, Lunceford JK, Rangwala R, Lubiniecki GM, Roach C, Emancipator K, Gandhi L (2015) Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med 372(21):2018–2028. doi:10.1056/NEJMoa1501824
-
(2015)
N Engl J Med
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
Leighl, N.4
Balmanoukian, A.S.5
Eder, J.P.6
Patnaik, A.7
Aggarwal, C.8
Gubens, M.9
Horn, L.10
Carcereny, E.11
Ahn, M.J.12
Felip, E.13
Lee, J.S.14
Hellmann, M.D.15
Hamid, O.16
Goldman, J.W.17
Soria, J.C.18
Dolled-Filhart, M.19
Rutledge, R.Z.20
Zhang, J.21
Lunceford, J.K.22
Rangwala, R.23
Lubiniecki, G.M.24
Roach, C.25
Emancipator, K.26
Gandhi, L.27
more..
-
28
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell Non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, Crino L, Eberhardt WE, Poddubskaya E, Antonia S, Pluzanski A, Vokes EE, Holgado E, Waterhouse D, Ready N, Gainor J, Aren Frontera O, Havel L, Steins M, Garassino MC, Aerts JG, Domine M, Paz-Ares L, Reck M, Baudelet C, Harbison CT, Lestini B, Spigel DR (2015) Nivolumab versus docetaxel in advanced squamous-cell Non-small-cell lung cancer. N Engl J Med. doi:10.1056/NEJMoa1504627
-
(2015)
N Engl J Med
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
Antonia, S.7
Pluzanski, A.8
Vokes, E.E.9
Holgado, E.10
Waterhouse, D.11
Ready, N.12
Gainor, J.13
Aren Frontera, O.14
Havel, L.15
Steins, M.16
Garassino, M.C.17
Aerts, J.G.18
Domine, M.19
Paz-Ares, L.20
Reck, M.21
Baudelet, C.22
Harbison, C.T.23
Lestini, B.24
Spigel, D.R.25
more..
-
29
-
-
84961235286
-
-
Bauer TM, McCleod M, Chandler JC, Blumenschein GR, Schwartzberg LS, Burris H, Waterhouse D, Jotte RM, Hussein M, Spigel DR An ongoing phase IIIb/IV safety trial of nivolumab (NIVO) in patients (pts) with advanced or metastatic non-small-cell lung cancer (NSCLC) who progressed after receiving 1 or more prior systemic regimens. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 3013
-
Bauer TM, McCleod M, Chandler JC, Blumenschein GR, Schwartzberg LS, Burris H, Waterhouse D, Jotte RM, Hussein M, Spigel DR An ongoing phase IIIb/IV safety trial of nivolumab (NIVO) in patients (pts) with advanced or metastatic non-small-cell lung cancer (NSCLC) who progressed after receiving 1 or more prior systemic regimens. In: ASCO Annual Meeting Proceedings, 2015. vol 15_suppl. p 3013
-
-
-
-
30
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
COI: 1:CAS:528:DC%2BC2MXisFGqsLg%3D, PID: 25399552
-
Robert C, Long GV, Brady B, Dutriaux C, Maio M, Mortier L, Hassel JC, Rutkowski P, McNeil C, Kalinka-Warzocha E, Savage KJ, Hernberg MM, Lebbe C, Charles J, Mihalcioiu C, Chiarion-Sileni V, Mauch C, Cognetti F, Arance A, Schmidt H, Schadendorf D, Gogas H, Lundgren-Eriksson L, Horak C, Sharkey B, Waxman IM, Atkinson V, Ascierto PA (2015) Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med 372(4):320–330. doi:10.1056/NEJMoa1412082
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
Dutriaux, C.4
Maio, M.5
Mortier, L.6
Hassel, J.C.7
Rutkowski, P.8
McNeil, C.9
Kalinka-Warzocha, E.10
Savage, K.J.11
Hernberg, M.M.12
Lebbe, C.13
Charles, J.14
Mihalcioiu, C.15
Chiarion-Sileni, V.16
Mauch, C.17
Cognetti, F.18
Arance, A.19
Schmidt, H.20
Schadendorf, D.21
Gogas, H.22
Lundgren-Eriksson, L.23
Horak, C.24
Sharkey, B.25
Waxman, I.M.26
Atkinson, V.27
Ascierto, P.A.28
more..
-
32
-
-
84929939531
-
The prognostic value of PD-L1 expression for non-small cell lung cancer patients: a meta-analysis
-
COI: 1:STN:280:DC%2BC2MrlsVCltA%3D%3D, PID: 25682184
-
Wang A, Wang HY, Liu Y, Zhao MC, Zhang HJ, Lu ZY, Fang YC, Chen XF, Liu GT (2015) The prognostic value of PD-L1 expression for non-small cell lung cancer patients: a meta-analysis. Eur J Surg Oncol 41(4):450–456. doi:10.1016/j.ejso.2015.01.020
-
(2015)
Eur J Surg Oncol
, vol.41
, Issue.4
, pp. 450-456
-
-
Wang, A.1
Wang, H.Y.2
Liu, Y.3
Zhao, M.C.4
Zhang, H.J.5
Lu, Z.Y.6
Fang, Y.C.7
Chen, X.F.8
Liu, G.T.9
-
33
-
-
84926429657
-
Prognostic significance of programmed cell death 1 (PD-1) or PD-1 ligand 1 (PD-L1) expression in epithelial-originated cancer: a meta-analysis
-
COI: 1:CAS:528:DC%2BC2MXjtVSjs74%3D, PID: 25674748
-
Zhang Y, Kang S, Shen J, He J, Jiang L, Wang W, Guo Z, Peng G, Chen G, He J, Liang W (2015) Prognostic significance of programmed cell death 1 (PD-1) or PD-1 ligand 1 (PD-L1) expression in epithelial-originated cancer: a meta-analysis. Medicine 94(6):e515. doi:10.1097/md.0000000000000515
-
(2015)
Medicine
, vol.94
, Issue.6
-
-
Zhang, Y.1
Kang, S.2
Shen, J.3
He, J.4
Jiang, L.5
Wang, W.6
Guo, Z.7
Peng, G.8
Chen, G.9
He, J.10
Liang, W.11
-
34
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
COI: 1:CAS:528:DC%2BC38XhtV2rs7fN, PID: 22658127
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M (2012) Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 366(26):2443–2454. doi:10.1056/NEJMoa1200690
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
Horn, L.14
Drake, C.G.15
Pardoll, D.M.16
Chen, L.17
Sharfman, W.H.18
Anders, R.A.19
Taube, J.M.20
McMiller, T.L.21
Xu, H.22
Korman, A.J.23
Jure-Kunkel, M.24
Agrawal, S.25
McDonald, D.26
Kollia, G.D.27
Gupta, A.28
Wigginton, J.M.29
Sznol, M.30
more..
-
35
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
COI: 1:CAS:528:DC%2BC2cXhs12gtbzK, PID: 24714771
-
Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, Chen L, Pardoll DM, Topalian SL, Anders RA (2014) Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 20(19):5064–5074. doi:10.1158/1078-0432.ccr-13-3271
-
(2014)
Clin Cancer Res
, vol.20
, Issue.19
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
Xu, H.4
Pan, X.5
Kim, J.H.6
Chen, L.7
Pardoll, D.M.8
Topalian, S.L.9
Anders, R.A.10
-
36
-
-
84928605037
-
Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis
-
PID: 25922725
-
Jia M, Feng W, Kang S, Zhang Y, Shen J, He J, Jiang L, Wang W, Guo Z, Peng G, Chen G, He J, Liang W (2015) Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis. J Thorac Dis 7(3):455–461. doi:10.3978/j.issn.2072-1439.2015.02.06
-
(2015)
J Thorac Dis
, vol.7
, Issue.3
, pp. 455-461
-
-
Jia, M.1
Feng, W.2
Kang, S.3
Zhang, Y.4
Shen, J.5
He, J.6
Jiang, L.7
Wang, W.8
Guo, Z.9
Peng, G.10
Chen, G.11
He, J.12
Liang, W.13
|