-
1
-
-
0026667073
-
Apolipoprotein (a) gene accounts for greater than 90 % of the variation in plasma lipoprotein (a) concentrations
-
COI: 1:CAS:528:DyaK38XltVyku7o%3D, PID: 1386087
-
Boerwinkle E, Leffert C, Lin J, Lackner C, Chiesa G, Hobbs HH. Apolipoprotein (a) gene accounts for greater than 90 % of the variation in plasma lipoprotein (a) concentrations. J Clin Invest. 1992;90:52–60.
-
(1992)
J Clin Invest
, vol.90
, pp. 52-60
-
-
Boerwinkle, E.1
Leffert, C.2
Lin, J.3
Lackner, C.4
Chiesa, G.5
Hobbs, H.H.6
-
2
-
-
0028245313
-
The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate
-
COI: 1:CAS:528:DyaK2cXlslGrtL0%3D, PID: 8201014
-
Rader DJ, Cain W, Ikewaki K, et al. The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate. J Clin Invest. 1994;93:2758–63.
-
(1994)
J Clin Invest
, vol.93
, pp. 2758-2763
-
-
Rader, D.J.1
Cain, W.2
Ikewaki, K.3
-
3
-
-
84856101806
-
Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) study
-
COI: 1:CAS:528:DC%2BC38XotVGisg%3D%3D, PID: 22128224
-
Virani SS, Brautbar A, Davis BC, et al. Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) study. Circulation. 2012;125:241–49.
-
(2012)
Circulation
, vol.125
, pp. 241-249
-
-
Virani, S.S.1
Brautbar, A.2
Davis, B.C.3
-
4
-
-
0026355887
-
Relationship of lipoprotein(a) to variables of coagulation and fibrinolysis in a healthy population
-
COI: 1:CAS:528:DyaK38Xkt1Oh, PID: 1834370
-
Heinrich J, Sandkamp M, Kokott R. Relationship of lipoprotein(a) to variables of coagulation and fibrinolysis in a healthy population. Clin Chem. 1991;37:1950–4.
-
(1991)
Clin Chem
, vol.37
, pp. 1950-1954
-
-
Heinrich, J.1
Sandkamp, M.2
Kokott, R.3
-
5
-
-
84884211406
-
Lipoprotein(a) metabolism: potential sites for therapeutic targets
-
COI: 1:CAS:528:DC%2BC38XhsVKgsb%2FO, PID: 23040268
-
Hoover-Plow J, Haung M. Lipoprotein(a) metabolism: potential sites for therapeutic targets. Metabolism. 2013;62:479–91.
-
(2013)
Metabolism
, vol.62
, pp. 479-491
-
-
Hoover-Plow, J.1
Haung, M.2
-
6
-
-
84888305389
-
Estrogens and cardiovascular disease risk revisited: the Women’s Health Initiative
-
COI: 1:CAS:528:DC%2BC3sXhslOmtrjJ, PID: 24184944
-
Howard BV, Roussouw JE. Estrogens and cardiovascular disease risk revisited: the Women’s Health Initiative. Curr Opin Lipidol. 2013;24:493–99.
-
(2013)
Curr Opin Lipidol
, vol.24
, pp. 493-499
-
-
Howard, B.V.1
Roussouw, J.E.2
-
7
-
-
0019997388
-
The natural history of coronary heart disease: prognostic factors after recovery from myocardial infarction in 2789 men. the 5-year findings of the coronary drug project
-
COI: 1:STN:280:DyaL383jsVWisA%3D%3D, PID: 7094247
-
Schlant RC, Forman S, Stamler J, Canner PL. The natural history of coronary heart disease: prognostic factors after recovery from myocardial infarction in 2789 men. the 5-year findings of the coronary drug project. Circulation. 1982;66(2):401–14.
-
(1982)
Circulation
, vol.66
, Issue.2
, pp. 401-414
-
-
Schlant, R.C.1
Forman, S.2
Stamler, J.3
Canner, P.L.4
-
8
-
-
0027716173
-
The relationship between serum levels of lipoprotein (a) and proteins associated with acute phase response
-
COI: 1:STN:280:DyaK2c7pt1anuw%3D%3D, PID: 7511489
-
Ledue TB, Neveux LM, Palomaki GE, Ritchie RF, Craig WY. The relationship between serum levels of lipoprotein (a) and proteins associated with acute phase response. Clin Chim Acta. 1993;223:73–82.
-
(1993)
Clin Chim Acta
, vol.223
, pp. 73-82
-
-
Ledue, T.B.1
Neveux, L.M.2
Palomaki, G.E.3
Ritchie, R.F.4
Craig, W.Y.5
-
9
-
-
0024391373
-
Transient changes of serum lipoprotein(a) as an acute phase protein
-
COI: 1:STN:280:DyaL1Mzpt1Wltw%3D%3D, PID: 2476992
-
Maeda S, Abe A, Seishima M, Makino K, Noma A, Kawade M. Transient changes of serum lipoprotein(a) as an acute phase protein. Atherosclerosis. 1989;78:145–50.
-
(1989)
Atherosclerosis
, vol.78
, pp. 145-150
-
-
Maeda, S.1
Abe, A.2
Seishima, M.3
Makino, K.4
Noma, A.5
Kawade, M.6
-
10
-
-
0027435729
-
The immediate effect of streptokinase on serum lipoprotein (a) concentration and the effect of myocardial infarction on serum lipoprotein (a), apolipoprotein A1 and B, lipids and C-reactive protein
-
COI: 1:CAS:528:DyaK2cXitFChsrs%3D, PID: 8280186
-
Mbewu AD, Durrington PN, Bulleid S, et al. The immediate effect of streptokinase on serum lipoprotein (a) concentration and the effect of myocardial infarction on serum lipoprotein (a), apolipoprotein A1 and B, lipids and C-reactive protein. Atherosclerosis. 1993;103:65–71.
-
(1993)
Atherosclerosis
, vol.103
, pp. 65-71
-
-
Mbewu, A.D.1
Durrington, P.N.2
Bulleid, S.3
-
11
-
-
0031880158
-
Month-to-month variability of lipids, lipoproteins, and apolipoproteins and the impact of acute infection in adolescents
-
COI: 1:CAS:528:DyaK1cXls1agsbo%3D, PID: 9709713
-
Gidding SS, Stone NJ, Bookstein LC, Laskarzewski PM, Stein EA. Month-to-month variability of lipids, lipoproteins, and apolipoproteins and the impact of acute infection in adolescents. J Pediatr. 1998;133:242–6.
-
(1998)
J Pediatr
, vol.133
, pp. 242-246
-
-
Gidding, S.S.1
Stone, N.J.2
Bookstein, L.C.3
Laskarzewski, P.M.4
Stein, E.A.5
-
12
-
-
0034083644
-
Major reduction in plasma Lp(a) levels during sepsis and burns
-
COI: 1:CAS:528:DC%2BD3cXjtV2hsb8%3D, PID: 10764684
-
Mooser V, Berger MM, Tappy L, Cayeux C, Markovina SM, Darioli R, et al. Major reduction in plasma Lp(a) levels during sepsis and burns. Arterioscler Thromb Vasc Biol. 2000;20:1137–42.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1137-1142
-
-
Mooser, V.1
Berger, M.M.2
Tappy, L.3
Cayeux, C.4
Markovina, S.M.5
Darioli, R.6
-
13
-
-
0027979982
-
Lp(a): an acute-phase reactant?
-
Noma A, Abe A, Maeda S. Lp(a): an acute-phase reactant? Chem Phys Lipids. 1994;67/68:411–17.
-
(1994)
Chem Phys Lipids
, vol.67-68
, pp. 411-417
-
-
Noma, A.1
Abe, A.2
Maeda, S.3
-
14
-
-
0027534292
-
Lipoprotein(a) and apolipoprotein B plasma concentrations in hypothyroid, euthyroid and hyperthyroid subjects
-
PID: 8421075
-
De Bruin T, van Barlingen H, van Linde-Sibenius TM, et al. Lipoprotein(a) and apolipoprotein B plasma concentrations in hypothyroid, euthyroid and hyperthyroid subjects. J Clin Endocrinol Metab. 1993;76:121–26.
-
(1993)
J Clin Endocrinol Metab
, vol.76
, pp. 121-126
-
-
De Bruin, T.1
van Barlingen, H.2
van Linde-Sibenius, T.M.3
-
15
-
-
77949349469
-
Use of the thyroid hormone analogue eprotirome in statin treated dyslipidemia
-
Landerson PW, Kristensen JD, Ridgeway EC, et al. Use of the thyroid hormone analogue eprotirome in statin treated dyslipidemia. N Engl J Med. 2010;362:906–16.
-
(2010)
N Engl J Med
, vol.362
, pp. 906-916
-
-
Landerson, P.W.1
Kristensen, J.D.2
Ridgeway, E.C.3
-
16
-
-
84901591020
-
Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo controlled phase 3 study
-
COI: 1:CAS:528:DC%2BC2cXptVaru70%3D, PID: 24731671
-
Sjouke B, Langslet G, Ceska R, et al. Eprotirome in patients with familial hypercholesterolaemia (the AKKA trial): a randomised, double-blind, placebo controlled phase 3 study. Lancet Diabetes Endocrinol. 2014;2:455–63.
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 455-463
-
-
Sjouke, B.1
Langslet, G.2
Ceska, R.3
-
17
-
-
0020624873
-
Studies on the role of specific cell surface receptors in the removal of lipoprotein(a) in man
-
COI: 1:CAS:528:DyaL3sXkt1Sitrs%3D, PID: 6304146
-
Krempler F, Kostner GM, Roscher A, et al. Studies on the role of specific cell surface receptors in the removal of lipoprotein(a) in man. J Clin Invest. 1983;71:1431–41.
-
(1983)
J Clin Invest
, vol.71
, pp. 1431-1441
-
-
Krempler, F.1
Kostner, G.M.2
Roscher, A.3
-
18
-
-
0031456893
-
LDL-mediated interaction of Lp(a) with HepG2 cells: a novel fluorescence microscopy approach
-
COI: 1:CAS:528:DyaK1cXitVOruw%3D%3D, PID: 9458265
-
Hofer G, Steyrer E, Kostner GM, Hermetter A. LDL-mediated interaction of Lp(a) with HepG2 cells: a novel fluorescence microscopy approach. J Lipid Res. 1997;38:2411–21.
-
(1997)
J Lipid Res
, vol.38
, pp. 2411-2421
-
-
Hofer, G.1
Steyrer, E.2
Kostner, G.M.3
Hermetter, A.4
-
19
-
-
0029022637
-
Effect of simvastatin on Lp(a) concentrations
-
Hafner S, Orchard T, Stein E, Schmidt D, LaBelle P. Effect of simvastatin on Lp(a) concentrations. Clin Cardiol. 1995;18:261–5.
-
(1995)
Clin Cardiol
, vol.18
, pp. 261-265
-
-
Hafner, S.1
Orchard, T.2
Stein, E.3
Schmidt, D.4
LaBelle, P.5
-
20
-
-
0027963479
-
Comparative effects of lovastatin and niacin in primary hypercholesterolemia: a prospective trial
-
COI: 1:STN:280:DyaK2czgsVaqug%3D%3D, PID: 8031206
-
Illingworth DR, Stein EA, Mitchel YB, Dujovne CA, Frost PH, Knopp RH, et al. Comparative effects of lovastatin and niacin in primary hypercholesterolemia: a prospective trial. Arch Intern Med. 1994;154:1586–95.
-
(1994)
Arch Intern Med
, vol.154
, pp. 1586-1595
-
-
Illingworth, D.R.1
Stein, E.A.2
Mitchel, Y.B.3
Dujovne, C.A.4
Frost, P.H.5
Knopp, R.H.6
-
21
-
-
0027241858
-
Effects of one year of treatment with pravastatin, an HMG-CoA reductase inhibitor, on lipoprotein a
-
COI: 1:STN:280:DyaK3sznsFSltA%3D%3D, PID: 8366183
-
Hunninghake DB, Stein EA, Mellies MJ. Effects of one year of treatment with pravastatin, an HMG-CoA reductase inhibitor, on lipoprotein a. J Clin Pharmacol. 1993;33(6):574–80.
-
(1993)
J Clin Pharmacol
, vol.33
, Issue.6
, pp. 574-580
-
-
Hunninghake, D.B.1
Stein, E.A.2
Mellies, M.J.3
-
22
-
-
0026344365
-
Serum Lp(a) concentrations are unaffected by treatment with the HMG-CoA reductase inhibitor Pravastatin: results of a 2-year investigation
-
COI: 1:CAS:528:DyaK38Xns1Wntg%3D%3D, PID: 1840246
-
Fieseler HG, Armstrong VW, Wieland E, Thiery J, Schutz E, Walli AK, et al. Serum Lp(a) concentrations are unaffected by treatment with the HMG-CoA reductase inhibitor Pravastatin: results of a 2-year investigation. Clin Chim Acta. 1991;204(1–3):291–300.
-
(1991)
Clin Chim Acta
, vol.204
, Issue.1-3
, pp. 291-300
-
-
Fieseler, H.G.1
Armstrong, V.W.2
Wieland, E.3
Thiery, J.4
Schutz, E.5
Walli, A.K.6
-
23
-
-
0036802128
-
Atorvastatin lowers lipoprotein(a) but not apolipoprotein(a) fragment levels in hypercholesterolemic subjects at high cardiovascular risk
-
COI: 1:CAS:528:DC%2BD38XmsVCrtL0%3D, PID: 12204802
-
Gonbert S, Malinsky S, Sposito AC, Laouenan H, Doucet C, Chapman MJ, et al. Atorvastatin lowers lipoprotein(a) but not apolipoprotein(a) fragment levels in hypercholesterolemic subjects at high cardiovascular risk. Atherosclerosis. 2002;164:305–11.
-
(2002)
Atherosclerosis
, vol.164
, pp. 305-311
-
-
Gonbert, S.1
Malinsky, S.2
Sposito, A.C.3
Laouenan, H.4
Doucet, C.5
Chapman, M.J.6
-
24
-
-
0043169544
-
Long term statin treatment reduces lipoprotein(a) concentrations in heterozygous familial hypercholesterolaemia
-
PID: 12860867
-
van Wissen S, Smilde TJ, Trip MD, de Boo T, Kastelein JJP, Stalenhoef AFH. Long term statin treatment reduces lipoprotein(a) concentrations in heterozygous familial hypercholesterolaemia. Heart. 2003;89:893–6.
-
(2003)
Heart
, vol.89
, pp. 893-896
-
-
van Wissen, S.1
Smilde, T.J.2
Trip, M.D.3
de Boo, T.4
Kastelein, J.J.P.5
Stalenhoef, A.F.H.6
-
25
-
-
84893853699
-
Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the use of statins in prevention: an Intervention Trial Evaluating Rosuvastatin)
-
COI: 1:CAS:528:DC%2BC2cXisF2kt7s%3D, PID: 24243886
-
Khera AV, Everett BM, Caulfield MP, Hantash FM, Wohlgemuth J, Ridker PM, et al. Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the use of statins in prevention: an Intervention Trial Evaluating Rosuvastatin). Circulation. 2014;129:635–42.
-
(2014)
Circulation
, vol.129
, pp. 635-642
-
-
Khera, A.V.1
Everett, B.M.2
Caulfield, M.P.3
Hantash, F.M.4
Wohlgemuth, J.5
Ridker, P.M.6
-
26
-
-
0031409345
-
Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study
-
COI: 1:STN:280:DyaK1c7nvV2gtQ%3D%3D, PID: 9520115
-
Berg K, Dahlen G, Christopherson B, et al. Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study. Clin Genet. 1997;52:254–61.
-
(1997)
Clin Genet
, vol.52
, pp. 254-261
-
-
Berg, K.1
Dahlen, G.2
Christopherson, B.3
-
27
-
-
0037044454
-
Inhibition of intestinal cholesterol absorption by ezetimibe in humans
-
COI: 1:CAS:528:DC%2BD38XnsVartrs%3D, PID: 12370217
-
Sudhop T, Lutjohann D, Kodal A, et al. Inhibition of intestinal cholesterol absorption by ezetimibe in humans. Circulation. 2002;106:1943–8.
-
(2002)
Circulation
, vol.106
, pp. 1943-1948
-
-
Sudhop, T.1
Lutjohann, D.2
Kodal, A.3
-
28
-
-
0037395141
-
Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia
-
Knopp RH, Gitter H, Truitt T. Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia. Eur Heart J. 2003;23:729–41.
-
(2003)
Eur Heart J
, vol.23
, pp. 729-741
-
-
Knopp, R.H.1
Gitter, H.2
Truitt, T.3
-
29
-
-
76249132266
-
Effects of ezetimibe on remnant-like particle cholesterol, lipoprotein(a) and oxidized low-density lipoprotein in patients with dyslipidaemia
-
COI: 1:CAS:528:DC%2BC3MXhvVerur8%3D, PID: 20075599
-
Nozue T, Michishati I, Mizuguchi I. Effects of ezetimibe on remnant-like particle cholesterol, lipoprotein(a) and oxidized low-density lipoprotein in patients with dyslipidaemia. J Atheroscler Thromb. 2010;17(1):37–44.
-
(2010)
J Atheroscler Thromb
, vol.17
, Issue.1
, pp. 37-44
-
-
Nozue, T.1
Michishati, I.2
Mizuguchi, I.3
-
30
-
-
0037188567
-
Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia
-
COI: 1:CAS:528:DC%2BD38XkvFehu7w%3D, PID: 12034651
-
Gagne C, Gaudet D, Bruckert E, et al. Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia. Circulation. 2002;105:2469–75.
-
(2002)
Circulation
, vol.105
, pp. 2469-2475
-
-
Gagne, C.1
Gaudet, D.2
Bruckert, E.3
-
31
-
-
80054712207
-
Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance
-
COI: 1:CAS:528:DC%2BC3MXhsFGrur3N, PID: 21995692
-
Moutzouri E, Liberopoulos E, Mikhailidis DP, et al. Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance. Int J Clin Pract. 2011;65:1141–8.
-
(2011)
Int J Clin Pract
, vol.65
, pp. 1141-1148
-
-
Moutzouri, E.1
Liberopoulos, E.2
Mikhailidis, D.P.3
-
32
-
-
80052380574
-
Farsenoid X receptor represses hepatic human apo(a) gene expression
-
COI: 1:CAS:528:DC%2BC3MXhtFOhtr7O, PID: 21804189
-
Chennamsetty I, Claudel T, Kostner KM, et al. Farsenoid X receptor represses hepatic human apo(a) gene expression. J Clin Invest. 2011;121:3724–34.
-
(2011)
J Clin Invest
, vol.121
, pp. 3724-3734
-
-
Chennamsetty, I.1
Claudel, T.2
Kostner, K.M.3
-
33
-
-
0022360376
-
Brewer HBJr, levels of lipoprotein (a) Lp(a) decline with neomycin and niacin treatment
-
COI: 1:STN:280:DyaL287gtlGmtg%3D%3D, PID: 2935163
-
Gurakar K, Hoeg JM, Kostner G, Papadopolous NM. Brewer HBJr, levels of lipoprotein (a) Lp(a) decline with neomycin and niacin treatment. Atherosclerosis. 1985;57:293–301.
-
(1985)
Atherosclerosis
, vol.57
, pp. 293-301
-
-
Gurakar, K.1
Hoeg, J.M.2
Kostner, G.3
Papadopolous, N.M.4
-
34
-
-
0024466520
-
Pronounced lowering of levels of lipoprotein (a) Lp(a) in hyperlipidemic subjects treated with nicotinic acid
-
COI: 1:STN:280:DyaK3c%2FjvFWjsQ%3D%3D, PID: 2530298
-
Carlson LA, Hamsten A, Asplund A. Pronounced lowering of levels of lipoprotein (a) Lp(a) in hyperlipidemic subjects treated with nicotinic acid. J Intern Med. 1989;226:271–6.
-
(1989)
J Intern Med
, vol.226
, pp. 271-276
-
-
Carlson, L.A.1
Hamsten, A.2
Asplund, A.3
-
35
-
-
0000369454
-
Efficacy and tolerability of low dose simvastatin and niacin, alone and in combination, in patients with combined hyperlipidemia: a prospective trial
-
COI: 1:CAS:528:DyaK28XlvFOntLk%3D, PID: 10684407
-
Stein EA, Davidson MH, Dujovne CA, Hunninghake DB, et al. Efficacy and tolerability of low dose simvastatin and niacin, alone and in combination, in patients with combined hyperlipidemia: a prospective trial. J Cardiovasc Pharmacol Ther. 1996;1:107–16.
-
(1996)
J Cardiovasc Pharmacol Ther
, vol.1
, pp. 107-116
-
-
Stein, E.A.1
Davidson, M.H.2
Dujovne, C.A.3
Hunninghake, D.B.4
-
36
-
-
0037158150
-
Sheehan JP; Diabetes Multicenter Research Group. Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial
-
COI: 1:CAS:528:DC%2BD38XlvFGktLs%3D, PID: 12123399
-
Grundy SM, Vega GL, McGovern ME, Tulloch BR, Kendall DM, Fitz-Patrick D, et al. Sheehan JP; Diabetes Multicenter Research Group. Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial. Arch Intern Med. 2002;162(14):1568–76.
-
(2002)
Arch Intern Med
, vol.162
, Issue.14
, pp. 1568-1576
-
-
Grundy, S.M.1
Vega, G.L.2
McGovern, M.E.3
Tulloch, B.R.4
Kendall, D.M.5
Fitz-Patrick, D.6
-
37
-
-
0032542302
-
Brody. Efficacy and safety of an extended-release niacin (Niaspan): a long-term study
-
COI: 1:CAS:528:DyaK1MXntFemug%3D%3D, PID: 9915666
-
Capuzzi DM, Guyton JR, Morgan JM, Goldberg AC, Kreisberg RA, Brusco OA. Brody. Efficacy and safety of an extended-release niacin (Niaspan): a long-term study. Am J Cardiol. 1998;82(12A):74U–81U.
-
(1998)
Am J Cardiol
, vol.82
, Issue.12A
, pp. 74U-81U
-
-
Capuzzi, D.M.1
Guyton, J.R.2
Morgan, J.M.3
Goldberg, A.C.4
Kreisberg, R.A.5
Brusco, O.A.6
-
38
-
-
0032542277
-
Clinical trial experience with extended-release niacin (Niaspan): dose-escalation study
-
COI: 1:CAS:528:DyaK1MXntFemtg%3D%3D, PID: 9915661
-
Goldberg AC. Clinical trial experience with extended-release niacin (Niaspan): dose-escalation study. Am J Cardiol. 1998;82(12A):35U–8U.
-
(1998)
Am J Cardiol
, vol.82
, Issue.12A
, pp. 35U-38U
-
-
Goldberg, A.C.1
-
39
-
-
0035105681
-
Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects
-
COI: 1:CAS:528:DC%2BD3MXisFyrtbw%3D, PID: 11175492
-
Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CRM, Coelho OR, Ramires JAF. Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects. Braz J Med Biol Res. 2001;34:177–82.
-
(2001)
Braz J Med Biol Res
, vol.34
, pp. 177-182
-
-
Sposito, A.C.1
Mansur, A.P.2
Maranhão, R.C.3
Rodrigues-Sobrinho, C.R.M.4
Coelho, O.R.5
Ramires, J.A.F.6
-
40
-
-
84867358576
-
Effects of prescription niacin and omega-3 fatty acids on lipids and vascular function in metabolic syndrome: a randomized controlled trial[S]
-
COI: 1:CAS:528:DC%2BC38XhsFClsrfL, PID: 22892157
-
Shearer GC, Pottala JV, Hansen SN, Brandenburg V, Harris WS. Effects of prescription niacin and omega-3 fatty acids on lipids and vascular function in metabolic syndrome: a randomized controlled trial[S]. J Lipid Res. 2012;53:2429–35.
-
(2012)
J Lipid Res
, vol.53
, pp. 2429-2435
-
-
Shearer, G.C.1
Pottala, J.V.2
Hansen, S.N.3
Brandenburg, V.4
Harris, W.S.5
-
41
-
-
84863582389
-
Antisense oligonucleotides for the treatment of dyslipidaemia
-
COI: 1:CAS:528:DC%2BC38XptVGntLk%3D, PID: 22634577
-
Visser ME, Witztum JL, Stroes ES, Kastelein JJ. Antisense oligonucleotides for the treatment of dyslipidaemia. Eur Heart J. 2012;33:1451–58.
-
(2012)
Eur Heart J
, vol.33
, pp. 1451-1458
-
-
Visser, M.E.1
Witztum, J.L.2
Stroes, E.S.3
Kastelein, J.J.4
-
42
-
-
84921866616
-
Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials
-
COI: 1:CAS:528:DC%2BC2MXjsVKhsLc%3D, PID: 25614280
-
Santos RD, Raal FJ, Catapano A, et al. Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials. Arterioscler Thromb Vasc Biol. 2015;35:689–99.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 689-699
-
-
Santos, R.D.1
Raal, F.J.2
Catapano, A.3
-
43
-
-
84924415690
-
Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolemia: 2-year interim results of an open-label extension
-
PID: 24366918
-
Santos RD, Duell PB, East C, et al. Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolemia: 2-year interim results of an open-label extension. Eur Heart J. 2015;36:566–75.
-
(2015)
Eur Heart J
, vol.36
, pp. 566-575
-
-
Santos, R.D.1
Duell, P.B.2
East, C.3
-
44
-
-
77949485460
-
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of lower LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC3cXjs1ait74%3D, PID: 20227758
-
Raal FJ, Santos RD, Blom DJ, et al. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of lower LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375:998–1006.
-
(2010)
Lancet
, vol.375
, pp. 998-1006
-
-
Raal, F.J.1
Santos, R.D.2
Blom, D.J.3
-
45
-
-
48349088178
-
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
-
COI: 1:CAS:528:DC%2BD1cXovV2ltrc%3D, PID: 18506154
-
Samaha FF, McKenney J, Bloedon LT, Sasiela WJ, Rader DJ. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat Clin Pract Cardiovasc Med. 2008;5:497–505.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, pp. 497-505
-
-
Samaha, F.F.1
McKenney, J.2
Bloedon, L.T.3
Sasiela, W.J.4
Rader, D.J.5
-
46
-
-
84871945617
-
Phase 3 HoFH Lomitapide Study Investigators. efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
-
COI: 1:CAS:528:DC%2BC38Xhs1ajsb%2FM, PID: 23122768
-
Cuchel M, Meagher EA, du Toit TH, Blom DJ, Marais AD, Hegele RA, et al. Phase 3 HoFH Lomitapide Study Investigators. efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. Lancet. 2013;381:40–6.
-
(2013)
Lancet
, vol.381
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
du Toit, T.H.3
Blom, D.J.4
Marais, A.D.5
Hegele, R.A.6
-
47
-
-
74749107585
-
Efficacy criteria and cholesterol targets for LDL apheresis
-
COI: 1:CAS:528:DC%2BC3cXhtlyru7w%3D, PID: 19589528
-
Thompson GR, Barbir M, Davies D, Dobral P, Gesinde M, Livingston M, et al. Efficacy criteria and cholesterol targets for LDL apheresis. Atherosclerosis. 2010;208:317–21.
-
(2010)
Atherosclerosis
, vol.208
, pp. 317-321
-
-
Thompson, G.R.1
Barbir, M.2
Davies, D.3
Dobral, P.4
Gesinde, M.5
Livingston, M.6
-
48
-
-
0026756999
-
For the Liposorber Study Group, treatment of refractory familial hypercholesterolemia by low-density lipoprotein apheresis using an automated dextran sulfate cellulose absorption system
-
COI: 1:STN:280:DyaK3s%2FjsV2nug%3D%3D, PID: 1414897
-
Gordon BR, Kelsey SF, Bilheimer DW, Brown DC, Dau PC, Gotto AM, et al. For the Liposorber Study Group, treatment of refractory familial hypercholesterolemia by low-density lipoprotein apheresis using an automated dextran sulfate cellulose absorption system. Am J Cardiol. 1992;70:1010–6.
-
(1992)
Am J Cardiol
, vol.70
, pp. 1010-1016
-
-
Gordon, B.R.1
Kelsey, S.F.2
Bilheimer, D.W.3
Brown, D.C.4
Dau, P.C.5
Gotto, A.M.6
-
49
-
-
84890904215
-
Lipoprotein apheresis in patients with maximally tolerated lipid-lowering therapy, lipoprotein(a)-hyperlipoproteinemia, and progressive cardiovascular disease: prospective observational multicenter study
-
COI: 1:CAS:528:DC%2BC3sXhvF2ktLzF, PID: 24056686
-
Leebmann J, Roeseler E, Julius U, Heigl F, et al. Lipoprotein apheresis in patients with maximally tolerated lipid-lowering therapy, lipoprotein(a)-hyperlipoproteinemia, and progressive cardiovascular disease: prospective observational multicenter study. Circulation. 2013;128:2567–76.
-
(2013)
Circulation
, vol.128
, pp. 2567-2576
-
-
Leebmann, J.1
Roeseler, E.2
Julius, U.3
Heigl, F.4
-
50
-
-
78549235583
-
For the DEFINE Investigators Safety of anacetrapib in patients with, or at high risk for coronary heart disease
-
COI: 1:CAS:528:DC%2BC3cXhsF2ltLfL, PID: 21082868
-
Cannon CP, Shah S, Dansky HM, Davidson M, Brinton EA, Gotto AM, et al. For the DEFINE Investigators Safety of anacetrapib in patients with, or at high risk for coronary heart disease. N Engl J Med. 2010;363:2406–15.
-
(2010)
N Engl J Med
, vol.363
, pp. 2406-2415
-
-
Cannon, C.P.1
Shah, S.2
Dansky, H.M.3
Davidson, M.4
Brinton, E.A.5
Gotto, A.M.6
-
51
-
-
84938748425
-
Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial
-
Hovingh GK, Kastelein JJP, van Deventer SJH, Round P, Ford J, Saleheen D, et al. Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet. 2015.
-
(2015)
Lancet
-
-
Hovingh, G.K.1
Kastelein, J.J.P.2
van Deventer, S.J.H.3
Round, P.4
Ford, J.5
Saleheen, D.6
-
52
-
-
84971280903
-
-
Evacetrapib alone or in combination with statins lowers lipoprotein(a) and total and small LDL particle concentrations in mildly hypercholesterolemic patients, J Clin Lipidol
-
Nicholls SJ, Ruotolo G, Brewer BH, Wang MD, Liu L, Willey MB, et al. Evacetrapib alone or in combination with statins lowers lipoprotein(a) and total and small LDL particle concentrations in mildly hypercholesterolemic patients. J Clin Lipidol. 2015. doi:10.1016/j.jacl.2015.11.014.
-
(2015)
et al
-
-
Nicholls, S.J.1
Ruotolo, G.2
Brewer, B.H.3
Wang, M.D.4
Liu, L.5
Willey, M.B.6
-
53
-
-
84961169530
-
-
HPS3/TIMI55 – REVEAL trial of Anacetrapib in high-risk vascular patients recruits the target of 30,000 participants [accessed January 10, 2016]
-
HPS3/TIMI55 – REVEAL trial of Anacetrapib in high-risk vascular patients recruits the target of 30,000 participantshttps://www.ctsu.ox.ac.uk/research/mega-trials/hps3-reveal [accessed January 10, 2016].
-
-
-
-
54
-
-
36348975228
-
Effects of torcetrapib in patients at high risk for coronary events
-
COI: 1:CAS:528:DC%2BD2sXhtlGns7bL, PID: 17984165
-
Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109–22.
-
(2007)
N Engl J Med
, vol.357
, pp. 2109-2122
-
-
Barter, P.J.1
Caulfield, M.2
Eriksson, M.3
Grundy, S.M.4
Kastelein, J.J.5
Komajda, M.6
-
55
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
COI: 1:CAS:528:DC%2BC38XhslyltrvK, PID: 23126252
-
Schwartz GG, Olsson AG, Abt M, et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367:2089–99.
-
(2012)
N Engl J Med
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Abt, M.3
-
56
-
-
84961183036
-
-
Lilly to discontinue development of evacetrapib for high-risk atherosclerotic cardiovascular disease. [accessed January 12, 2016]
-
Lilly to discontinue development of evacetrapib for high-risk atherosclerotic cardiovascular disease. https://investor.lilly.com/releasedetail.cfm?ReleaseID=936130 [accessed January 12, 2016].
-
-
-
-
57
-
-
84858638369
-
Effect of a monoclonal antibody to PCSK9 on LDL cholesterol
-
COI: 1:CAS:528:DC%2BC38XktlCqtLY%3D, PID: 22435370
-
Stein EA, Mellis S, Yancopoulos GD, Stahl N, Logan D, Smith WB, et al. Effect of a monoclonal antibody to PCSK9 on LDL cholesterol. N Engl J Med. 2012;366:1108–18.
-
(2012)
N Engl J Med
, vol.366
, pp. 1108-1118
-
-
Stein, E.A.1
Mellis, S.2
Yancopoulos, G.D.3
Stahl, N.4
Logan, D.5
Smith, W.B.6
-
58
-
-
84897471477
-
Reduction in lipoprotein (a) with the PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of over 1300 patients in 4 phase 2 trials
-
COI: 1:CAS:528:DC%2BC2cXltl2msbo%3D, PID: 24509273
-
Raal FJ, Giugliano RP, Sabatine MS, Koren MJ, Langslet G, Bays H, et al. Reduction in lipoprotein (a) with the PCSK9 monoclonal antibody evolocumab (AMG 145): a pooled analysis of over 1300 patients in 4 phase 2 trials. J Am Coll Cardiol. 2014;63(13):1278–88.
-
(2014)
J Am Coll Cardiol
, vol.63
, Issue.13
, pp. 1278-1288
-
-
Raal, F.J.1
Giugliano, R.P.2
Sabatine, M.S.3
Koren, M.J.4
Langslet, G.5
Bays, H.6
-
59
-
-
84926191670
-
Efficacy and safety of alirocumab in reducing lipids and cardiovascular events
-
COI: 1:CAS:528:DC%2BC2MXotFGlsbc%3D, PID: 25773378
-
Robinson JG, Farnier M, Krempf M, et al. Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. N Engl J Med. 2015;372:1489–99.
-
(2015)
N Engl J Med
, vol.372
, pp. 1489-1499
-
-
Robinson, J.G.1
Farnier, M.2
Krempf, M.3
-
60
-
-
84903754236
-
Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolemia not adequately controlled with current lipid-lowering therapy: design and rationale of the ODYSSEY FH studies
-
COI: 1:CAS:528:DC%2BC2cXosFansbw%3D, PID: 24842558
-
Kastelein JJ, Robinson JG, Farnier M, Krempf M, Langslet G, Lorenzato C, et al. Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolemia not adequately controlled with current lipid-lowering therapy: design and rationale of the ODYSSEY FH studies. Cardiovasc Drugs Ther. 2014;28(3):281–9.
-
(2014)
Cardiovasc Drugs Ther
, vol.28
, Issue.3
, pp. 281-289
-
-
Kastelein, J.J.1
Robinson, J.G.2
Farnier, M.3
Krempf, M.4
Langslet, G.5
Lorenzato, C.6
-
61
-
-
84947976529
-
Donahue S Efficacy and safety of adding alirocumab to rosuvastatin versus adding ezetimibe or doubling the rosuvastatin dose in high cardiovascular risk patients: The ODYSSEY OPTIONS II randomized trial
-
COI: 1:CAS:528:DC%2BC2MXhvFems7fL, PID: 26638010
-
Farnier M, Jones P, Severance R, Averna M, Steinhagen-Thiessen E, Colhoun HM, et al. Donahue S Efficacy and safety of adding alirocumab to rosuvastatin versus adding ezetimibe or doubling the rosuvastatin dose in high cardiovascular risk patients: The ODYSSEY OPTIONS II randomized trial. Atherosclerosis. 2016;244:138–46.
-
(2016)
Atherosclerosis
, vol.244
, pp. 138-146
-
-
Farnier, M.1
Jones, P.2
Severance, R.3
Averna, M.4
Steinhagen-Thiessen, E.5
Colhoun, H.M.6
-
62
-
-
84862219022
-
Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy
-
COI: 1:CAS:528:DC%2BC38XovV2ntLs%3D, PID: 22463922
-
McKenney JM, Koren MJ, Kereiakes DJ, Hanotin C, Ferrand A-C, Stein EA. Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy. J Am Coll Cardiol. 2012;59:2344–53.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2344-2353
-
-
McKenney, J.M.1
Koren, M.J.2
Kereiakes, D.J.3
Hanotin, C.4
Ferrand, A.-C.5
Stein, E.A.6
-
63
-
-
84926206074
-
Efficacy and safety of evolocumab in reducing lipids and cardiovascular events
-
COI: 1:CAS:528:DC%2BC2MXotFGlsL8%3D, PID: 25773607
-
Sabatine MS, Giugliano RP, Wiviott SD, Raal FJ, Blom DJ, Robinson J, et al. Efficacy and safety of evolocumab in reducing lipids and cardiovascular events. New Engl J Med. 2015;372:1500–9.
-
(2015)
New Engl J Med
, vol.372
, pp. 1500-1509
-
-
Sabatine, M.S.1
Giugliano, R.P.2
Wiviott, S.D.3
Raal, F.J.4
Blom, D.J.5
Robinson, J.6
-
64
-
-
84960138958
-
Antisense inhibition of apolipoprotein(a) to lower plasma lipoprotein(a) levels in humans
-
Graham MJ, Viney N, Crooke R, Tsimikas S. Antisense inhibition of apolipoprotein(a) to lower plasma lipoprotein(a) levels in humans. J Lipid Res. 2015 Nov 4.
-
(2015)
J Lipid Res
, pp. 4
-
-
Graham, M.J.1
Viney, N.2
Crooke, R.3
Tsimikas, S.4
-
65
-
-
84944152398
-
Antisense therapy 674 targeting apolipoprotein(a): a randomised, double-blind, placebo- 675 controlled phase 1 study
-
Tsimikas S, Viney NJ, Hughes SG, et al. Antisense therapy 674 targeting apolipoprotein(a): a randomised, double-blind, placebo- 675 controlled phase 1 study. Lancet. 2015;386:1472–83.
-
(2015)
Lancet
, vol.386
, pp. 1472-1483
-
-
Tsimikas, S.1
Viney, N.J.2
Hughes, S.G.3
|