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Volumn 10, Issue 3, 2016, Pages 519-527.e4

Evacetrapib alone or in combination with statins lowers lipoprotein(a) and total and small LDL particle concentrations in mildly hypercholesterolemic patients

Author keywords

CETP inhibitor; Evacetrapib; Hypercholesterolemia; LDL particle; Lipoprotein(a); Small LDL

Indexed keywords

APOLIPOPROTEIN B; ATORVASTATIN; EVACETRAPIB; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN; PLACEBO; ROSUVASTATIN; SIMVASTATIN; VERY LOW DENSITY LIPOPROTEIN; BENZODIAZEPINE DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84971280903     PISSN: 19332874     EISSN: 18764789     Source Type: Journal    
DOI: 10.1016/j.jacl.2015.11.014     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • C. Baigent, A. Keech, P.M. Kearney, and et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins Lancet 366 2005 1267 1278
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 2
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: A meta-analysis of data from 170,000 participants in 26 randomised trials
    • C. Baigent, L. Blackwell, J. Emberson, and et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials Lancet 376 2010 1670 1681
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3
  • 3
    • 84931411520 scopus 로고    scopus 로고
    • Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
    • C.P. Cannon, M.A. Blazing, R.P. Giugliano, and et al. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes N Engl J Med 372 2015 2387 2397
    • (2015) N Engl J Med , vol.372 , pp. 2387-2397
    • Cannon, C.P.1    Blazing, M.A.2    Giugliano, R.P.3
  • 4
    • 84859184996 scopus 로고    scopus 로고
    • Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: A meta-analysis
    • S.M. Boekholdt, B.J. Arsenault, S. Mora, and et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis JAMA 307 2012 1302 1309
    • (2012) JAMA , vol.307 , pp. 1302-1309
    • Boekholdt, S.M.1    Arsenault, B.J.2    Mora, S.3
  • 5
    • 0037044396 scopus 로고    scopus 로고
    • Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women
    • G.J. Blake, J.D. Otvos, N. Rifai, and P.M. Ridker Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women Circulation 106 2002 1930 1937
    • (2002) Circulation , vol.106 , pp. 1930-1937
    • Blake, G.J.1    Otvos, J.D.2    Rifai, N.3    Ridker, P.M.4
  • 6
    • 33846639147 scopus 로고    scopus 로고
    • Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: The EPIC-Norfolk Prospective Population Study
    • K. El Harchaoui, W.A. van der Steeg, E.S. Stroes, and et al. Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study J Am Coll Cardiol 49 2007 547 553
    • (2007) J Am Coll Cardiol , vol.49 , pp. 547-553
    • El Harchaoui, K.1    Van Der Steeg, W.A.2    Stroes, E.S.3
  • 7
    • 0029740950 scopus 로고    scopus 로고
    • Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women
    • C.D. Gardner, S.P. Fortmann, and R.M. Krauss Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women JAMA 276 1996 875 881
    • (1996) JAMA , vol.276 , pp. 875-881
    • Gardner, C.D.1    Fortmann, S.P.2    Krauss, R.M.3
  • 8
    • 84899548103 scopus 로고    scopus 로고
    • All low-density lipoprotein particles are not created equal
    • R.M. Krauss All low-density lipoprotein particles are not created equal Arterioscler Thromb Vasc Biol 34 2014 959 961
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 959-961
    • Krauss, R.M.1
  • 9
    • 61849110301 scopus 로고    scopus 로고
    • Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women
    • S. Mora, J.D. Otvos, N. Rifai, R.S. Rosenson, J.E. Buring, and P.M. Ridker Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women Circulation 119 2009 931 939
    • (2009) Circulation , vol.119 , pp. 931-939
    • Mora, S.1    Otvos, J.D.2    Rifai, N.3    Rosenson, R.S.4    Buring, J.E.5    Ridker, P.M.6
  • 10
    • 84922062274 scopus 로고    scopus 로고
    • Use of lipoprotein particle measures for assessing coronary heart disease risk post-American Heart Association/American College of Cardiology guidelines: The Multi-Ethnic Study of Atherosclerosis
    • B.T. Steffen, W. Guan, A.T. Remaley, and et al. Use of lipoprotein particle measures for assessing coronary heart disease risk post-American Heart Association/American College of Cardiology guidelines: the Multi-Ethnic Study of Atherosclerosis Arterioscler Thromb Vasc Biol 35 2015 448 454
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. 448-454
    • Steffen, B.T.1    Guan, W.2    Remaley, A.T.3
  • 11
    • 85027944383 scopus 로고    scopus 로고
    • Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study
    • S. Parish, A. Offer, R. Clarke, and et al. Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study Circulation 125 2012 2469 2478
    • (2012) Circulation , vol.125 , pp. 2469-2478
    • Parish, S.1    Offer, A.2    Clarke, R.3
  • 12
    • 84899656061 scopus 로고    scopus 로고
    • Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
    • R.C. Hoogeveen, J.W. Gaubatz, W. Sun, and et al. Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study Arterioscler Thromb Vasc Biol 34 2014 1069 1077
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 1069-1077
    • Hoogeveen, R.C.1    Gaubatz, J.W.2    Sun, W.3
  • 13
    • 78649888517 scopus 로고    scopus 로고
    • Lipoprotein(a) as a cardiovascular risk factor: Current status
    • B.G. Nordestgaard, M.J. Chapman, K. Ray, and et al. Lipoprotein(a) as a cardiovascular risk factor: current status Eur Heart J 31 2010 2844 2853
    • (2010) Eur Heart J , vol.31 , pp. 2844-2853
    • Nordestgaard, B.G.1    Chapman, M.J.2    Ray, K.3
  • 14
    • 78549235583 scopus 로고    scopus 로고
    • Safety of anacetrapib in patients with or at high risk for coronary heart disease
    • C.P. Cannon, S. Shah, H.M. Dansky, and et al. Safety of anacetrapib in patients with or at high risk for coronary heart disease N Engl J Med 363 2010 2406 2415
    • (2010) N Engl J Med , vol.363 , pp. 2406-2415
    • Cannon, C.P.1    Shah, S.2    Dansky, H.M.3
  • 15
    • 84938748425 scopus 로고    scopus 로고
    • Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): A randomised, double-blind, placebo-controlled phase 2 trial
    • G.K. Hovingh, J.J. Kastelein, S.J. van Deventer, and et al. Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial Lancet 386 2015 452 460
    • (2015) Lancet , vol.386 , pp. 452-460
    • Hovingh, G.K.1    Kastelein, J.J.2    Van Deventer, S.J.3
  • 16
    • 81255125373 scopus 로고    scopus 로고
    • Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: A randomized controlled trial
    • S.J. Nicholls, H.B. Brewer, J.J. Kastelein, and et al. Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial JAMA 306 2011 2099 2109
    • (2011) JAMA , vol.306 , pp. 2099-2109
    • Nicholls, S.J.1    Brewer, H.B.2    Kastelein, J.J.3
  • 17
    • 84938740733 scopus 로고    scopus 로고
    • The evolving role of CETP inhibition: Beyond HDL cholesterol
    • K.K. Ray, and A.J. Vallejo-Vaz The evolving role of CETP inhibition: beyond HDL cholesterol Lancet 386 2015 412 414
    • (2015) Lancet , vol.386 , pp. 412-414
    • Ray, K.K.1    Vallejo-Vaz, A.J.2
  • 18
    • 33750804460 scopus 로고    scopus 로고
    • Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy
    • E.J. Jeyarajah, W.C. Cromwell, and J.D. Otvos Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy Clin Lab Med 26 2006 847 870
    • (2006) Clin Lab Med , vol.26 , pp. 847-870
    • Jeyarajah, E.J.1    Cromwell, W.C.2    Otvos, J.D.3
  • 19
    • 0030022839 scopus 로고    scopus 로고
    • Quantification of lipoprotein(a): Comparison of an automated latex-enhanced nephelometric assay with an immunoenzymometric method
    • H.H. Schmidt, J.C. Genschel, S. Wagner, and M.P. Manns Quantification of lipoprotein(a): comparison of an automated latex-enhanced nephelometric assay with an immunoenzymometric method Eur J Clin Chem Clin Biochem 34 1996 119 124
    • (1996) Eur J Clin Chem Clin Biochem , vol.34 , pp. 119-124
    • Schmidt, H.H.1    Genschel, J.C.2    Wagner, S.3    Manns, M.P.4
  • 20
    • 0029038845 scopus 로고
    • The log transformation is special
    • O.N. Keene The log transformation is special Stat Med 14 1995 811 819
    • (1995) Stat Med , vol.14 , pp. 811-819
    • Keene, O.N.1
  • 21
    • 84908363070 scopus 로고    scopus 로고
    • Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials)
    • D. Gaudet, D.J. Kereiakes, J.M. McKenney, and et al. Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials) Am J Cardiol 114 2014 711 715
    • (2014) Am J Cardiol , vol.114 , pp. 711-715
    • Gaudet, D.1    Kereiakes, D.J.2    McKenney, J.M.3
  • 22
    • 84921866616 scopus 로고    scopus 로고
    • Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: Results of 4 phase III trials
    • R.D. Santos, F.J. Raal, A.L. Catapano, J.L. Witztum, E. Steinhagen-Thiessen, and S. Tsimikas Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials Arterioscler Thromb Vasc Biol 35 2015 689 699
    • (2015) Arterioscler Thromb Vasc Biol , vol.35 , pp. 689-699
    • Santos, R.D.1    Raal, F.J.2    Catapano, A.L.3    Witztum, J.L.4    Steinhagen-Thiessen, E.5    Tsimikas, S.6
  • 23
    • 84886911170 scopus 로고    scopus 로고
    • Screening for and management of elevated Lp(a)
    • M.B. Boffa, and M.L. Koschinsky Screening for and management of elevated Lp(a) Curr Cardiol Rep 15 2013 417
    • (2013) Curr Cardiol Rep , vol.15 , pp. 417
    • Boffa, M.B.1    Koschinsky, M.L.2
  • 24
    • 84971341667 scopus 로고    scopus 로고
    • Mechanisms by which anacetrapib lowers plasma Lipoprotein (a) concentration
    • Abstract
    • T.A. Thomas, H. Zhou, T. Roddy, and et al. Mechanisms by which anacetrapib lowers plasma Lipoprotein (a) concentration Arterioscler Thromb Vasc Biol 32 5 Suppl 2012 A329 Abstract
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , Issue.5 , pp. A329
    • Thomas, T.A.1    Zhou, H.2    Roddy, T.3
  • 25
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • W.E. Boden, J.L. Probstfield, T. Anderson, and et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy N Engl J Med 365 2011 2255 2267
    • (2011) N Engl J Med , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 26
    • 84904252744 scopus 로고    scopus 로고
    • Effects of extended-release niacin with laropiprant in high-risk patients
    • M.J. Landray, R. Haynes, J.C. Hopewell, and et al. Effects of extended-release niacin with laropiprant in high-risk patients N Engl J Med 371 2014 203 212
    • (2014) N Engl J Med , vol.371 , pp. 203-212
    • Landray, M.J.1    Haynes, R.2    Hopewell, J.C.3
  • 27
    • 84927694074 scopus 로고    scopus 로고
    • Changes in LDL particle concentrations after treatment with the cholesteryl ester transfer protein inhibitor anacetrapib alone or in combination with atorvastatin
    • R.M. Krauss, C.A. Pinto, Y. Liu, A.O. Johnson-Levonas, and H.M. Dansky Changes in LDL particle concentrations after treatment with the cholesteryl ester transfer protein inhibitor anacetrapib alone or in combination with atorvastatin J Clin Lipidol 9 2015 93 102
    • (2015) J Clin Lipidol , vol.9 , pp. 93-102
    • Krauss, R.M.1    Pinto, C.A.2    Liu, Y.3    Johnson-Levonas, A.O.4    Dansky, H.M.5
  • 28
    • 84863232685 scopus 로고    scopus 로고
    • Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib
    • R.M. Krauss, K. Wojnooski, J. Orr, and et al. Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib J Lipid Res 53 2012 540 547
    • (2012) J Lipid Res , vol.53 , pp. 540-547
    • Krauss, R.M.1    Wojnooski, K.2    Orr, J.3
  • 29
    • 0023881202 scopus 로고
    • Small polydisperse low density lipoproteins in familial hyperalphalipoproteinemia with complete deficiency of cholesteryl ester transfer activity
    • S. Yamashita, Y. Matsuzawa, M. Okazaki, and et al. Small polydisperse low density lipoproteins in familial hyperalphalipoproteinemia with complete deficiency of cholesteryl ester transfer activity Atherosclerosis 70 1988 7 12
    • (1988) Atherosclerosis , vol.70 , pp. 7-12
    • Yamashita, S.1    Matsuzawa, Y.2    Okazaki, M.3
  • 30
    • 84896301841 scopus 로고    scopus 로고
    • Comparison of four methods of analysis of lipoprotein particle subfractions for their association with angiographic progression of coronary artery disease
    • P.T. Williams, X.Q. Zhao, S.M. Marcovina, J.D. Otvos, B.G. Brown, and R.M. Krauss Comparison of four methods of analysis of lipoprotein particle subfractions for their association with angiographic progression of coronary artery disease Atherosclerosis 233 2014 713 720
    • (2014) Atherosclerosis , vol.233 , pp. 713-720
    • Williams, P.T.1    Zhao, X.Q.2    Marcovina, S.M.3    Otvos, J.D.4    Brown, B.G.5    Krauss, R.M.6
  • 31
    • 48949097245 scopus 로고    scopus 로고
    • Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis
    • M.P. Caulfield, S. Li, G. Lee, and et al. Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis Clin Chem 54 2008 1307 1316
    • (2008) Clin Chem , vol.54 , pp. 1307-1316
    • Caulfield, M.P.1    Li, S.2    Lee, G.3
  • 32
    • 33750477286 scopus 로고    scopus 로고
    • Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels
    • M.H. Davidson, J.M. McKenney, C.L. Shear, and J.H. Revkin Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels J Am Coll Cardiol 48 2006 1774 1781
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1774-1781
    • Davidson, M.H.1    McKenney, J.M.2    Shear, C.L.3    Revkin, J.H.4
  • 33
    • 33750447972 scopus 로고    scopus 로고
    • Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin
    • J.M. McKenney, M.H. Davidson, C.L. Shear, and J.H. Revkin Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin J Am Coll Cardiol 48 2006 1782 1790
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1782-1790
    • McKenney, J.M.1    Davidson, M.H.2    Shear, C.L.3    Revkin, J.H.4
  • 34
    • 84930402044 scopus 로고    scopus 로고
    • Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects
    • J.S. Millar, G. Reyes-Soffer, P. Jumes, and et al. Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects J Clin Invest 125 2015 2510 2522
    • (2015) J Clin Invest , vol.125 , pp. 2510-2522
    • Millar, J.S.1    Reyes-Soffer, G.2    Jumes, P.3
  • 35
    • 84946763626 scopus 로고    scopus 로고
    • Cholesterol efflux capacity and pre-beta-1 HDL concentrations are increased in dyslipidemic patients treated with evacetrapib
    • S.J. Nicholls, G. Ruotolo, H.B. Brewer, and et al. Cholesterol efflux capacity and pre-beta-1 HDL concentrations are increased in dyslipidemic patients treated with evacetrapib J Am Coll Cardiol 66 2015 2201 2210
    • (2015) J Am Coll Cardiol , vol.66 , pp. 2201-2210
    • Nicholls, S.J.1    Ruotolo, G.2    Brewer, H.B.3
  • 36
    • 78651379500 scopus 로고    scopus 로고
    • Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
    • A.V. Khera, M. Cuchel, M. Llera-Moya, and et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis N Engl J Med 364 2011 127 135
    • (2011) N Engl J Med , vol.364 , pp. 127-135
    • Khera, A.V.1    Cuchel, M.2    Llera-Moya, M.3
  • 37
    • 84919343998 scopus 로고    scopus 로고
    • HDL cholesterol efflux capacity and incident cardiovascular events
    • A. Rohatgi, A. Khera, J.D. Berry, and et al. HDL cholesterol efflux capacity and incident cardiovascular events N Engl J Med 371 2014 2383 2393
    • (2014) N Engl J Med , vol.371 , pp. 2383-2393
    • Rohatgi, A.1    Khera, A.2    Berry, J.D.3
  • 38
    • 84879113852 scopus 로고    scopus 로고
    • Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks
    • X.M. Li, W.H. Tang, M.K. Mosior, and et al. Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks Arterioscler Thromb Vasc Biol 33 2013 1696 1705
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1696-1705
    • Li, X.M.1    Tang, W.H.2    Mosior, M.K.3
  • 39
    • 84942658792 scopus 로고    scopus 로고
    • Abstract 12252: Effects of the Cholesteryl Ester Transfer Protein Inhibitor, Evacetrapib, Administered as Monotherapy or in Combination with Statins on Cholesterol Efflux and HDL Particles in Patients with Dyslipidemia
    • D.J. Rader, G. Ruotolo, J.P. Kane, and et al. Abstract 12252: Effects of the Cholesteryl Ester Transfer Protein Inhibitor, Evacetrapib, Administered as Monotherapy or in Combination With Statins on Cholesterol Efflux and HDL Particles in Patients With Dyslipidemia Circulation 130 2014 A12252
    • (2014) Circulation , vol.130 , pp. A12252
    • Rader, D.J.1    Ruotolo, G.2    Kane, J.P.3
  • 40
    • 84863984491 scopus 로고    scopus 로고
    • Prebeta-1 HDL and coronary heart disease
    • J.P. Kane, and M.J. Malloy Prebeta-1 HDL and coronary heart disease Curr Opin Lipidol 23 2012 367 371
    • (2012) Curr Opin Lipidol , vol.23 , pp. 367-371
    • Kane, J.P.1    Malloy, M.J.2
  • 41
    • 0141885327 scopus 로고    scopus 로고
    • Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress
    • A. Kontush, S. Chantepie, and M.J. Chapman Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress Arterioscler Thromb Vasc Biol 23 2003 1881 1888
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1881-1888
    • Kontush, A.1    Chantepie, S.2    Chapman, M.J.3
  • 42
    • 33847368173 scopus 로고    scopus 로고
    • Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
    • T. Vaisar, S. Pennathur, P.S. Green, and et al. Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL J Clin Invest 117 2007 746 756
    • (2007) J Clin Invest , vol.117 , pp. 746-756
    • Vaisar, T.1    Pennathur, S.2    Green, P.S.3


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