메뉴 건너뛰기




Volumn 53, Issue 3, 2016, Pages 1661-1671

Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway

Author keywords

Akt1; Caspase 3; Ischemia reperfusion; JNK3; Sevoflurane

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE 3; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE B; PROTEIN PRAS40; SEVOFLURANE; UNCLASSIFIED DRUG; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANDROSTANE DERIVATIVE; CHROMONE DERIVATIVE; ETHER DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 10; MORPHOLINE DERIVATIVE; NEUROPROTECTIVE AGENT; WORTMANNIN;

EID: 84961139200     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9111-8     Document Type: Article
Times cited : (47)

References (35)
  • 2
    • 67349230835 scopus 로고    scopus 로고
    • The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice
    • COI: 1:CAS:528:DC%2BD1MXntVKmtLo%3D, PID: 19341776
    • Kim DH, Kim S, Jung WY, Park SJ, Park DH, Kim JM, Cheong JH, Ryu JH (2009) The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice. Food Chem Toxicol 47:1473–1479
    • (2009) Food Chem Toxicol , vol.47 , pp. 1473-1479
    • Kim, D.H.1    Kim, S.2    Jung, W.Y.3    Park, S.J.4    Park, D.H.5    Kim, J.M.6    Cheong, J.H.7    Ryu, J.H.8
  • 3
    • 0027442021 scopus 로고
    • Sevoflurane and halothane reduce focal ischemic brain damage in the rat, Possible influence on thermoregulation
    • COI: 1:CAS:528:DyaK2cXpsFCmug%3D%3D, PID: 8239017
    • Warner DS, McFarlane C, Todd MM, Ludwig P, McAllister AM (1993) Sevoflurane and halothane reduce focal ischemic brain damage in the rat, Possible influence on thermoregulation. Anesthesiology 79:985–992
    • (1993) Anesthesiology , vol.79 , pp. 985-992
    • Warner, D.S.1    McFarlane, C.2    Todd, M.M.3    Ludwig, P.4    McAllister, A.M.5
  • 5
    • 18244386778 scopus 로고    scopus 로고
    • Sevoflurane and nitrous oxide increase regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) in a drug-specific manner in human volunteers
    • COI: 1:CAS:528:DC%2BD38Xms1Gqug%3D%3D, PID: 11804751
    • Kolbitsch C, Lorenz IH, Hormann C, Kremser C, Schocke M, Felber S, Moser PL, Hinteregger M et al (2001) Sevoflurane and nitrous oxide increase regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) in a drug-specific manner in human volunteers. Magn Reson Imaging 19:1253–1260
    • (2001) Magn Reson Imaging , vol.19 , pp. 1253-1260
    • Kolbitsch, C.1    Lorenz, I.H.2    Hormann, C.3    Kremser, C.4    Schocke, M.5    Felber, S.6    Moser, P.L.7    Hinteregger, M.8
  • 7
    • 13844262649 scopus 로고    scopus 로고
    • Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats
    • COI: 1:CAS:528:DC%2BD2MXhtlSmtb0%3D, PID: 15713266
    • Payne RS, Akca O, Roewer N, Schurr A, Kehl F (2005) Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. Brain Res 1034:147–152
    • (2005) Brain Res , vol.1034 , pp. 147-152
    • Payne, R.S.1    Akca, O.2    Roewer, N.3    Schurr, A.4    Kehl, F.5
  • 8
    • 84878396325 scopus 로고    scopus 로고
    • Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats
    • COI: 1:CAS:528:DC%2BC3sXptFCqt7w%3D, PID: 23628555
    • Hu X, Zhang Y, Li W, Liu J, Li Y (2013) Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. Int J Dev Neurosci 31:328–333
    • (2013) Int J Dev Neurosci , vol.31 , pp. 328-333
    • Hu, X.1    Zhang, Y.2    Li, W.3    Liu, J.4    Li, Y.5
  • 9
    • 84866392999 scopus 로고    scopus 로고
    • Sevoflurane and isoflurane preconditioning provides neuroprotection by inhibition of apoptosis-related mRNA expression in a rat model of focal cerebral ischemia
    • PID: 22871953
    • Bedirli N, Bagriacik EU, Emmez H, Yilmaz G, Unal Y, Ozkose Z (2012) Sevoflurane and isoflurane preconditioning provides neuroprotection by inhibition of apoptosis-related mRNA expression in a rat model of focal cerebral ischemia. J Neurosurg Anesthesiol 24:336–344
    • (2012) J Neurosurg Anesthesiol , vol.24 , pp. 336-344
    • Bedirli, N.1    Bagriacik, E.U.2    Emmez, H.3    Yilmaz, G.4    Unal, Y.5    Ozkose, Z.6
  • 10
    • 79953226626 scopus 로고    scopus 로고
    • Sevoflurane preconditioning induces neuroprotection through reactive oxygen species-mediated up-regulation of antioxidant enzymes in rats
    • COI: 1:CAS:528:DC%2BC3MXjslKrtrg%3D, PID: 21385986
    • Yang Q, Dong H, Deng J, Wang Q, Ye R, Li X, Hu S, Dong H et al (2011) Sevoflurane preconditioning induces neuroprotection through reactive oxygen species-mediated up-regulation of antioxidant enzymes in rats. Anesth Analg 112:931–937
    • (2011) Anesth Analg , vol.112 , pp. 931-937
    • Yang, Q.1    Dong, H.2    Deng, J.3    Wang, Q.4    Ye, R.5    Li, X.6    Hu, S.7    Dong, H.8
  • 11
    • 84863982590 scopus 로고    scopus 로고
    • Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation
    • PID: 21720900
    • Ye Z, Guo Q, Wang N, Xia P, Yuan Y, Wang E (2012) Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation. Neurol Sci 33:239–249
    • (2012) Neurol Sci , vol.33 , pp. 239-249
    • Ye, Z.1    Guo, Q.2    Wang, N.3    Xia, P.4    Yuan, Y.5    Wang, E.6
  • 12
    • 84862945450 scopus 로고    scopus 로고
    • Inhibition of sevoflurane postconditioning against cerebral ischemia reperfusion-induced oxidative injury in rats
    • COI: 1:CAS:528:DC%2BC38Xpt1Shuw%3D%3D
    • Zhang Y, Zhang FG, Meng C, Tian SY, Wang YX, Zhao W, Chen J, Zhang XS et al (2012) Inhibition of sevoflurane postconditioning against cerebral ischemia reperfusion-induced oxidative injury in rats. Molecules 17:341–354
    • (2012) Molecules , vol.17 , pp. 341-354
    • Zhang, Y.1    Zhang, F.G.2    Meng, C.3    Tian, S.Y.4    Wang, Y.X.5    Zhao, W.6    Chen, J.7    Zhang, X.S.8
  • 13
    • 23644454848 scopus 로고    scopus 로고
    • The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation
    • COI: 1:CAS:528:DC%2BD2MXnslyisbo%3D, PID: 16018989
    • Hui L, Pei DS, Zhang QG, Guan QH, Zhang GY (2005) The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation. Brain Res 1052:1–9
    • (2005) Brain Res , vol.1052 , pp. 1-9
    • Hui, L.1    Pei, D.S.2    Zhang, Q.G.3    Guan, Q.H.4    Zhang, G.Y.5
  • 14
    • 53649106357 scopus 로고    scopus 로고
    • Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways
    • COI: 1:CAS:528:DC%2BD1cXhsVOgsrrI, PID: 18802401
    • Bayascas JR (2008) Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways. Cell Cycle 7:2978–2982
    • (2008) Cell Cycle , vol.7 , pp. 2978-2982
    • Bayascas, J.R.1
  • 15
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • COI: 1:CAS:528:DyaK1cXisFyntb4%3D, PID: 9561851
    • Downward J (1998) Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10:262–267
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 262-267
    • Downward, J.1
  • 16
    • 84893465991 scopus 로고    scopus 로고
    • Neuroprotective effect of pAkt and HIF-1 alpha on ischemia rats
    • COI: 1:CAS:528:DC%2BC2cXitV2gurk%3D, PID: 24507644
    • Liu BN, Han BX, Liu F (2014) Neuroprotective effect of pAkt and HIF-1 alpha on ischemia rats. Asian Pac J Trop Med 7:221–225
    • (2014) Asian Pac J Trop Med , vol.7 , pp. 221-225
    • Liu, B.N.1    Han, B.X.2    Liu, F.3
  • 17
    • 84896268983 scopus 로고    scopus 로고
    • PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways
    • COI: 1:CAS:528:DC%2BC2cXmslajtbY%3D, PID: 24583056
    • Xiong X, Xie R, Zhang H, Gu L, Xie W, Cheng M, Jian Z, Kovacina K et al (2014) PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways. Neurobiol Dis 66:43–52
    • (2014) Neurobiol Dis , vol.66 , pp. 43-52
    • Xiong, X.1    Xie, R.2    Zhang, H.3    Gu, L.4    Xie, W.5    Cheng, M.6    Jian, Z.7    Kovacina, K.8
  • 18
    • 0035965345 scopus 로고    scopus 로고
    • A kinase-independent function of Ask1 in caspase-independent cell death
    • COI: 1:CAS:528:DC%2BD3MXnt1yku7k%3D, PID: 11493600
    • Charette SJ, Lambert H, Landry J (2001) A kinase-independent function of Ask1 in caspase-independent cell death. J Biol Chem 276:36071–36074
    • (2001) J Biol Chem , vol.276 , pp. 36071-36074
    • Charette, S.J.1    Lambert, H.2    Landry, J.3
  • 19
    • 84870464850 scopus 로고    scopus 로고
    • The neuroprotective effect of losartan through inhibiting AT1/ASK1/MKK4/JNK3 pathway following cerebral I/R in rat hippocampal CA1 region
    • COI: 1:CAS:528:DC%2BC3sXhsVWlsrw%3D, PID: 23095236
    • Zhang TL, Fu JL, Geng Z, Yang JJ, Sun XJ (2012) The neuroprotective effect of losartan through inhibiting AT1/ASK1/MKK4/JNK3 pathway following cerebral I/R in rat hippocampal CA1 region. CNS Neurosci Ther 18:981–987
    • (2012) CNS Neurosci Ther , vol.18 , pp. 981-987
    • Zhang, T.L.1    Fu, J.L.2    Geng, Z.3    Yang, J.J.4    Sun, X.J.5
  • 20
    • 79952752665 scopus 로고    scopus 로고
    • Protective effect of FK506 on myocardial ischemia/reperfusion injury by suppression of CaN and ASK1 signaling circuitry
    • COI: 1:CAS:528:DC%2BC3MXhs1Cqt7Y%3D, PID: 21076890
    • Feng X, Li J, Liu J, Jin M, Liu X, Du H, Zhang L, Sun Z et al (2011) Protective effect of FK506 on myocardial ischemia/reperfusion injury by suppression of CaN and ASK1 signaling circuitry. Cardiovasc Toxicol 11:18–27
    • (2011) Cardiovasc Toxicol , vol.11 , pp. 18-27
    • Feng, X.1    Li, J.2    Liu, J.3    Jin, M.4    Liu, X.5    Du, H.6    Zhang, L.7    Sun, Z.8
  • 21
    • 0035048206 scopus 로고    scopus 로고
    • Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus
    • COI: 1:CAS:528:DC%2BD3MXntFKju7g%3D, PID: 11323521
    • Yano S, Morioka M, Fukunaga K, Kawano T, Hara T, Kai Y, Hamada J, Miyamoto E et al (2001) Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus. J Cereb Blood Flow Metab 21:351–360
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 351-360
    • Yano, S.1    Morioka, M.2    Fukunaga, K.3    Kawano, T.4    Hara, T.5    Kai, Y.6    Hamada, J.7    Miyamoto, E.8
  • 22
    • 84876301610 scopus 로고    scopus 로고
    • Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuroinflammation and apoptosis after neonatal ischemic brain damage
    • COI: 1:CAS:528:DC%2BC3sXivFyjtbg%3D, PID: 23376684
    • Nijboer CH, Bonestroo HJ, Zijlstra J, Kavelaars A, Heijnen CJ (2013) Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuroinflammation and apoptosis after neonatal ischemic brain damage. Neurobiol Dis 54:432–444
    • (2013) Neurobiol Dis , vol.54 , pp. 432-444
    • Nijboer, C.H.1    Bonestroo, H.J.2    Zijlstra, J.3    Kavelaars, A.4    Heijnen, C.J.5
  • 24
    • 84884785768 scopus 로고    scopus 로고
    • Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats
    • PID: 24083559
    • Liu G, Song J, Guo Y, Wang T, Zhou Z (2013) Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats. Behav Brain Funct: BBF 9:36
    • (2013) Behav Brain Funct: BBF , vol.9 , pp. 36
    • Liu, G.1    Song, J.2    Guo, Y.3    Wang, T.4    Zhou, Z.5
  • 25
    • 0038004740 scopus 로고    scopus 로고
    • Targeting JNK for therapeutic benefit: from junk to gold?
    • COI: 1:CAS:528:DC%2BD3sXks1Oru7c%3D, PID: 12815381
    • Manning AM, Davis RJ (2003) Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov 2:554–565
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 554-565
    • Manning, A.M.1    Davis, R.J.2
  • 26
    • 33845990232 scopus 로고    scopus 로고
    • Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway
    • PID: 17184578
    • Wang Q, Zhang QG, Wu DN, Yin XH, Zhang GY (2007) Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway. Acta Pharmacol Sin 28:19–27
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 19-27
    • Wang, Q.1    Zhang, Q.G.2    Wu, D.N.3    Yin, X.H.4    Zhang, G.Y.5
  • 27
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • COI: 1:STN:280:DyaE1M3is1amtQ%3D%3D, PID: 37614
    • Pulsinelli WA, Brierley JB (1979) A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10:267–272
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 28
    • 80053616485 scopus 로고    scopus 로고
    • Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia
    • Yu Q, Chu M, Wang H, Lu S, Gao H, Li P, Gan Y, Shi H et al (2011) Sevoflurane preconditioning protects blood-brain-barrier against brain ischemia. Front Biosci 3:978–988
    • (2011) Front Biosci , vol.3 , pp. 978-988
    • Yu, Q.1    Chu, M.2    Wang, H.3    Lu, S.4    Gao, H.5    Li, P.6    Gan, Y.7    Shi, H.8
  • 29
    • 84878641281 scopus 로고    scopus 로고
    • miR-15b suppression of Bcl-2 contributes to cerebral ischemic injury and is reversed by sevoflurane preconditioning
    • COI: 1:CAS:528:DC%2BC3sXpsVaqsLk%3D, PID: 23469855
    • Shi H, Sun BL, Zhang J, Lu S, Zhang P, Wang H, Yu Q, Stetler RA et al (2013) miR-15b suppression of Bcl-2 contributes to cerebral ischemic injury and is reversed by sevoflurane preconditioning. CNS Neurol Disord Drug Targets 12:381–391
    • (2013) CNS Neurol Disord Drug Targets , vol.12 , pp. 381-391
    • Shi, H.1    Sun, B.L.2    Zhang, J.3    Lu, S.4    Zhang, P.5    Wang, H.6    Yu, Q.7    Stetler, R.A.8
  • 30
    • 85027929787 scopus 로고    scopus 로고
    • Activation of canonical notch signaling pathway is involved in the ischemic tolerance induced by sevoflurane preconditioning in mice
    • COI: 1:CAS:528:DC%2BC38XhsFOqurrE, PID: 22929735
    • Yang Q, Yan W, Li X, Hou L, Dong H, Wang Q, Dong H, Wang S et al (2012) Activation of canonical notch signaling pathway is involved in the ischemic tolerance induced by sevoflurane preconditioning in mice. Anesthesiology 117:996–1005
    • (2012) Anesthesiology , vol.117 , pp. 996-1005
    • Yang, Q.1    Yan, W.2    Li, X.3    Hou, L.4    Dong, H.5    Wang, Q.6    Dong, H.7    Wang, S.8
  • 31
    • 84862816912 scopus 로고    scopus 로고
    • The effects of metabotropic glutamate receptor 7 allosteric agonist N, N'-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase signaling pathway
    • COI: 1:CAS:528:DC%2BC38XjsFKmu7c%3D
    • Wang WY, Wang H, Luo Y, Jia LJ, Zhao JN, Zhang HH, Ma ZW, Xue QS et al (2012) The effects of metabotropic glutamate receptor 7 allosteric agonist N, N'-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase signaling pathway. Neurosci 205:167–177
    • (2012) Neurosci , vol.205 , pp. 167-177
    • Wang, W.Y.1    Wang, H.2    Luo, Y.3    Jia, L.J.4    Zhao, J.N.5    Zhang, H.H.6    Ma, Z.W.7    Xue, Q.S.8
  • 32
    • 82755179964 scopus 로고    scopus 로고
    • Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia-reperfusion injury: role of AMP-activated protein kinase pathway
    • COI: 1:CAS:528:DC%2BC38XhsFOqtb4%3D
    • Song T, Lv LY, Xu J, Tian ZY, Cui WY, Wang QS, Qu G, Shi XM (2011) Diet-induced obesity suppresses sevoflurane preconditioning against myocardial ischemia-reperfusion injury: role of AMP-activated protein kinase pathway. Exp Biol Med (Maywood) 236:1427–1436
    • (2011) Exp Biol Med (Maywood) , vol.236 , pp. 1427-1436
    • Song, T.1    Lv, L.Y.2    Xu, J.3    Tian, Z.Y.4    Cui, W.Y.5    Wang, Q.S.6    Qu, G.7    Shi, X.M.8
  • 33
    • 53249105313 scopus 로고    scopus 로고
    • Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury
    • COI: 1:CAS:528:DC%2BD1cXht1egu77J
    • Wen XR, Li C, Zong YY, Yu CZ, Xu J, Han D, Zhang GY (2008) Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury. Neurosci 156:483–497
    • (2008) Neurosci , vol.156 , pp. 483-497
    • Wen, X.R.1    Li, C.2    Zong, Y.Y.3    Yu, C.Z.4    Xu, J.5    Han, D.6    Zhang, G.Y.7
  • 35
    • 0036208147 scopus 로고    scopus 로고
    • Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain
    • COI: 1:CAS:528:DC%2BD38Xjt1Ogsbo%3D, PID: 11919513
    • Gill R, Soriano M, Blomgren K, Hagberg H, Wybrecht R, Miss MT, Hoefer S, Adam G et al (2002) Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain. J Cereb Blood Flow Metab 22:420–430
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 420-430
    • Gill, R.1    Soriano, M.2    Blomgren, K.3    Hagberg, H.4    Wybrecht, R.5    Miss, M.T.6    Hoefer, S.7    Adam, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.