Poly(β-l-malic acid) (PMLA) from Aureobasidium spp. and its current proceedings

Applied Microbiology and Biotechnology

Volumn 100, Issue 9, 2016, Pages 3841-3851

  Chi, Zhe ^a   Liu, Guang Lei ^a   Liu, Chen Guang ^a   Chi, Zhen Ming ^a  

^a OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Aureobasidium spp; Biosynthesis; Poly( l malic acid); Potential application

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABILITY; BIOSYNTHESIS;

AUREOBASIDIUM SPP; BIOSYNTHESIS PATHWAYS; CHEMICALLY MODIFIED; DRUG DELIVERY SYSTEM; IMMUNOGENICITY; L-MALIC ACID; NATURAL BIOPOLYMERS; WATER SOLUBILITIES;

BIOCHEMISTRY;

BIOPOLYMER; NANOCONJUGATE; NANOPARTICLE; POLY(BETA MALIC ACID); UNCLASSIFIED DRUG; MALIC ACID DERIVATIVE; POLY(MALATE); POLYMER;

BIOCHEMISTRY; BIOTECHNOLOGY; DRUG; EXPLOITATION; FUNGUS; ORGANIC ACID; TECHNOLOGY ADOPTION;

AUREOBASIDIUM; BIOSYNTHESIS; DEGRADATION; DRUG DELIVERY SYSTEM; FOOD INDUSTRY; MICROBIAL DIVERSITY; NONHUMAN; REVIEW; ASCOMYCETES; GENETICS; METABOLISM;

AUREOBASIDIUM; FUNGI;

ASCOMYCOTA; BIOSYNTHETIC PATHWAYS; MALATES; POLYMERS;

EID: 84961114557     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-016-7404-0     Document Type: Review

References (50)

1. Amartey S, Jeffries TW (1994) Comparison of corn steep liquor with other nutrients in the fermentation of D-xylose by Pichia stipitis CBS 6054. Biotechnol Lett 16:211–214
2. Brown SH, Bashkirova L, Berka R (2013) Metabolic engineering of Aspergillus oryzae NRRL 3488 for increased production of L-malic acid. Appl Microbiol Biotechnol 97:8903–8912
3. Cao W, Luo J, Zhao J, Qiao C, Ding L, Qi B, Su Y, Wan Y (2012) Intensification of β-poly(L-malic acid) production by Aureobasidium pullulans ipe-1 in the late exponential growth phase. J Ind Microbiol Biotechnol 39:1073–1080
4. Cao W, Qi B, Zhao J (2013) Control strategy of pH, dissolved oxygen concentration and stirring speed for enhancing β-poly (malic acid) production by Aureobasidium pullulans ipe-1. J Chem Technol Biotech 88:808–817
5. Caruelle JP, Barritault D, Jeanbat-Mimaud V, Cammas-Marion S, Langlois V, Guerin P, Barbaud C (2000) Bioactive functionalized polymer of malic acid for bone repair and muscle regeneration. J Biomat Sci Polym Edition 11:979–991
6. Chen X, Xu G, Xu N (2013) Metabolic engineering of Torulopsis glabrata for malate production. Metab Eng 19:10–16
7. Chi Z, Wang XX, Geng Q, Chi ZM (2013) Role of a GATA-type transcriptional repressor Sre1 in regulation of siderophore biosynthesis in the marine derived Aureobasidium pullulans HN6.2. Biomet 26:955–967
8. Chi Z, Wang XX, Ma ZC, Chi ZM (2012) The unique role of siderophore in marine-derived Aureobasidium pullulans HN6.2. Biomet 25:219–230
9. Chi Z, Wang ZP, Wang GY, Khan I, Chi ZM (2016) Microbial biosynthesis and secretion of L-malic acid and its applications. Crit Rev Biotechnol 36(1):99–107
10. Chi ZM, Wang F, Chi Z (2009) Bioproducts from Aureobasidium pullulans, a biotechnologically important yeast. Appl Microbiol Biotechnol 82:793–804
11. DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM (2013) Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Res 41(7):4336–4343
12. Fischer H, Erdmann S, Holler E (1989) An unusual polyanion from Physarum polycephalum that inhibits homologous DNA polymerase α in vitro. Biochem 28:5219–5225
13. Fournié P, Domurado D, Guérin P, Braud C, Vert M, Madelmont JC (1990) In vivo fate of end-chain radiolabelled poly(β-malic acid), a water soluble biodegradable drug carrier. J Bioact Compat Polym 5:381–395
14. Fournié P, Domurado D, Guérin P, Braud C, Vert M, Pontikis R (1992) In vivo fate of repeat-unitradiolabelled poly(β-malic acid), a potential drug carrier. J Bioact Compat Polym 7:113–129
15. Gasslmaier B, Gasslmaier E (1997) Specificity and direction of depolymerization of poly (L-malate) catalysed by polymalatase from Physarum polycephalum. Eur J Biochem 250:308–314
16. Giese H, Sondergaard TE, Sørensen JL (2013) The AreA transcription factor in Fusarium graminearum regulates the use of some nonpreferred nitrogen sources and secondary metabolite production. Fung Biol 117:814–821
17. Gödde C, Liebergesell M, Steinbüchel A (1999) Isolation of poly (L-L-malic acid)-degrading bacteria and purification and characterization of the PMA hydrolase from Comamonas acidovorans strain 7789. FEMS Microbiol Lett 173:365–372
18. Goldberg I, Rokem JS, Pines O (2006) Organic acids: old metabolites, new themes. J Chem Technol Biotechnol 81:1601–1611
19. Gostinčar C, Ohm RA, Kogej T, Sonjak S, Turk M, Zajc J, Zalar P, Grube M, Sun H, Han J, Sharma A, Chiniquy J, Ngan CY, Lipzen A, Barry K, Grigoriev IV, Gunde-Cimerman N (2014) Genome sequencing of four Aureobasidium pullulans varieties: biotechnological potential, stress tolerance, and description of new species. BMC Genom 15:549–550
20. Holler E, Angerer B, Achhammer G, Miller S, Windisch C (1992) Biological and biosynthetic properties of poly-L-malate. FEMS Microbiol Rev 103:109–118
21. Huang ZW, Laurent V, Chetouania G, Ljubimova JY, Holler E, Benvegnua T, Loyer P, Sandrine Cammas-Marion S (2012) New functional degradable and bio-compatible nanoparticles based on poly(malic acid) derivatives for site-specific anti-cancer drug delivery. Intern J Pharma 423:84–92
22. Kajiyama T, Kobayashi H, Taguchi T, Saito H, Kamatsu Y, Kataoka K, Tanaka J (2004) Synthesis of activated poly(α,β-malic acid) using N-hydroxysuccinimide and its gelation with collagen as biomaterials. Materials Sci Eng C 24:815–819
23. Karl M, Holler E (1998) Multiple polypetides immunologically related to L-poly(L malate) hydrolase (polymalatase) in the plasmodium of the slime mold Physarum polycephalum. Eur J Biochem 251:405–412
24. Khan I, Nazir K, Wang ZP, Liu GL, Chi ZM (2014) Calcium malate overproduction by Penicillium viticola 152 using the medium containing corn steep liquor. Appl Microbiol Biotechnol 98:1539–1546
25. Knuf C, Nookaew I, Brown SH (2013) Investigation of malic acid production in Aspergillus oryzae under nitrogen starvation conditions. Appl Environ Microbiol 79:6050–6058
26. Korherr C, Roth R, Holler E (1995) Poly(L-L-malate) hydrolase from plasmodia of Physarum polycephalum. Can J Microbiol 41:192–199
27. Leathers TD, Manitchotpisit P (2013) Production of poly(β-L-malic acid) (PMA) from agricultural biomass substrates by Aureobasidium pullulans. Biotechnol Lett 35:83–89
28. Lee BS, Holler E (1999) Effects of culture conditions on β-poly(L-malate) production by Physarum polycephalum. Appl Microbiol Biotechnol 51:647–652
29. Lee BS, Maurer T, Kalbitzer HR, Holler E (1999) β-Poly (L-malate) production by Physarum polycephalum. 13C Nuclear magnetic resonance studies. Appl Microbiol Biotechnol 52:415–420
30. Li Y, Chi Z, Wang GY, Wang ZP, Liu GL, Lee CF, Ma ZC, Chi ZM (2015) Taxonomy of Aureobasidium spp. and biosynthesis and regulation of their extracellular polymers. Crit Rev Microbiol 41:228–237
31. Li BX, Zhang N, Peng Q, Yin T, Guan FF, Wang GL, Y L (2009) Production of pigment-free pullulan by swollen cell in Aureobasidium pullulans NG which cell differentiation was affected by pH and nutrition. Appl Microbiol Biotechnol 84:293–300
32. Liu SJ, Steinbüchel A (1996) Investigation of poly(β-L-malic acid) production by strains of Aureobasidium pullulans. Appl Microbiol Biotechnol 46:273–278
33. Liu SJ, Steinbüchel A (1997) Production of poly(malic acid) from different carbon sources and its regulation in Aureobasidium pullulans. Biotechnol Lett 19:11–14
34. Ma Y, Wang GY, Liu GL, Wang ZP, Chi ZM (2013) Overproduction of poly(β-malic acid) (PMA) from glucose by a novel Aureobasidium sp. P6 strain isolated from mangrove system. Appl Microbiol Biotechnol 97:8931–8939
35. Ma ZC, Chi Z, Geng Q, Chi ZM (2012) Disruption of the pullulan synthetase gene in siderophore-producing Aureobasidium pullulans enhances siderophore production and simplifies siderophore extraction. Proc Biochem 47:1807–1812
36. Ma ZC, Liu NN, Chi Z, Liu GL, Chi ZM (2015) Genetic modification of the marine-isolated yeast Aureobasidium melanogenum P16 for efficient pullulan production from inulin. Mar Biotechnol 17:511–522
37. Manitchotpisit P, Skory CD, Peterson SW, Price NPJ, Karl E, Vermillion KE, Leathers TD (2012) Poly(β-L-malic acid) production by diverse phylogenetic clades of Aureobasidium pullulans. J Ind Microbiol Biotechnol 39:125–132
38. Nagata N, Nakahara T, Tabuchi T (1993) Fermentative production of poly(β-L-malic acid), a polyelectolytic biopolyester by Aureobasidium sp. Biosci Biotechnol Biochem 57:638–642
39. Nakajima-Kambe T, Hirotani N, Nakahara T (1996) Poly(betamalic acid) production by the non-growing cells of Aureobasidium sp strain A-91. J Ferm Bioeng 82:411–413
40. Rathberger K, Reiner H, Willibald B (1999) Comparative synthesis and hydrolytic degradation of poly(L-malate) by myxomycetes and fungi. Mycol Res 103:513–520
41. Rødkær SV, Færgeman NJ (2014) Glucose- and nitrogen sensing and regulatory mechanisms in Saccharomyces cerevisiae. FEMS Yeast Res 14:683–696
42. Schaeffer SM, Nakata PA (2015) CRISPR/Cas9-mediated genome editing and gene replacement in plants: transitioning from lab to field. Plant Sci 240:130–142
43. Shimada K, Matsushi K, Fukumoto J, Yamamoto T (1969) Poly(β)-malic acid—a new protease inhibitor from Penicillium cyclopium. Biochem Biophy Res Commun 35:619–624
44. Vert M, Lenz RW (1979) Preparation and properties of poly-beta-malic acid: a functional polyester of potential biomedical importance. Am. Chem. Soc. Div. Polym Chem Prepr 20:608–611
45. 2+-polymalate (PMA) with high molecular mass by Aureobasidium pullulans var. pullulans MCW. Microb Cell Fact. doi:10.1186/s12934-015-0296-3
46. Willibald B, Bildl W, Lee BS, Holler E (1999) Is β-poly(L-malate) synthesis catalysed by a combination of β-L-malyl-AMP-ligase and β-poly(L-malate) polymerase? Eur J Biochem 265:1085–1090
47. Zan Z, Zou X (2013) Efficient production of polymalic acid from raw sweet potato hydrolysate with immobilized cells of Aureobasidium pullulans CCTCC M2012223 in aerobic fibrous bed bioreactor. J Chem Technol Biotechnol. doi:10.1002/jctb.4033
48. Zelle RM, de Hulster E, Kloezen W (2010) Key process conditions for production of C4 dicarboxylic acids in bioreactor batch cultures of an engineered Saccharomyces cerevisiae strain. Appl Environ Microbiol 76:744–750
49. Zhang H, Cai J, Dong J, Zhang D, Huang L, Xu Z, Cen P (2011) High-level production of poly(β-L-malic acid) with a new isolated Aureobasidium pullulans strain. Appl Microbiol Biotechnol 92:295–303
50. Zou X, Zhou Y, Yang ST (2013) Production of polymalic acid and malic acid by Aureobasidium pullulans fermentation and acid hydrolysis. Biotechnol Bioeng 110:2105–2113