Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR

Journal of Molecular Diagnostics

Volumn 18, Issue 2, 2016, Pages 235-243

  Jackson, Jennifer B ^a   Choi, Daniel S ^a   Luketich, James D ^b   Pennathur, Arjun ^b   Ståhlberg, Anders ^a,c   Godfrey, Tony E ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULATING TUMOR DNA; DNA; PROTEIN P53; SMAD4 PROTEIN; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; KRAS PROTEIN, HUMAN; PROTEIN P21; SMAD4 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

ALLELE; ARTICLE; CANCER PATIENT; CASE REPORT; DIGITAL POLYMERASE CHAIN REACTION; DNA EXTRACTION; GENE AMPLIFICATION; GENOTYPE; HUMAN; HUMAN TISSUE; MULTIPLE CANCER; MUTANT; NEOPLASM; POINT MUTATION; POLYMERASE CHAIN REACTION; SIGNAL NOISE RATIO; BLOOD; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; GENETICS; METABOLISM; NUCLEIC ACID AMPLIFICATION; PROCEDURES; SENSITIVITY AND SPECIFICITY;

DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-DIRECTED DNA POLYMERASE; GENE FREQUENCY; HUMANS; NEOPLASMS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS P21(RAS); SENSITIVITY AND SPECIFICITY; SMAD4 PROTEIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84960937089     PISSN: 15251578     EISSN: 19437811     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2015.10.004     Document Type: Article

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