Determining lower limits of detection of digital PCR assays for cancer-related gene mutations

Biomolecular Detection and Quantification

Volumn 1, Issue 1, 2014, Pages 8-22

  Milbury, Coren A ^a   Zhong, Qun ^a   Lin, Jesse ^a   Williams, Miguel ^a   Olson, Jeff ^a   Link, Darren R ^a   Hutchison, Brian ^a  

^a RainDance Technologies   (United States)

Author keywords

Assay sensitivity; Digital PCR; EGFR L858R; EGFR T790M; Limit of detection; Mutation detection

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GENOMIC DNA;

ANALYTICAL PARAMETERS; ARTICLE; CONTROLLED STUDY; DIGITAL POLYMERASE CHAIN REACTION; GEL ELECTROPHORESIS; GENE MUTATION; GENETIC ANALYSIS; HUMAN; LIMIT OF DETECTION; LINEARITY; MATHEMATICAL PARAMETERS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SENSITIVITY; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY; TUMOR GENE;

EID: 84921996965     PISSN: None     EISSN: 22147535     Source Type: Journal    
DOI: 10.1016/j.bdq.2014.08.001     Document Type: Article

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