Multidrug Resistance in Quinolone-Resistant Gram-Negative Bacteria Isolated from Hospital Effluent and the Municipal Wastewater Treatment Plant

Microbial Drug Resistance

Volumn 22, Issue 2, 2016, Pages 155-163

  Vaz Moreira, Ivone ^a   Varela, Ana Rita ^a   Pereira, Thamiris V ^a   Fochat, Romário C ^a   Manaia, Célia M ^a  

^a UNIVERSIDADE CATÓLICA PORTUGUESA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; AMOXICILLIN; CARBAPENEM; CEFALOTIN; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; MEROPENEM; QUINOLONE; STREPTOMYCIN; SULFAMETHOXAZOLE; SULFONAMIDE; ANTIINFECTIVE AGENT; CARBAPENEM DERIVATIVE; QUINOLONE DERIVATIVE; WASTE DISPOSAL; WASTE WATER;

ACINETOBACTER; AEROMONAS; ANTIBIOTIC RESISTANCE; AQUATIC ENVIRONMENT; ARTICLE; BACTERIUM ISOLATE; CHRYSEOBACTERIUM; CITROBACTER; CONTROLLED STUDY; EFFLUENT; ENTEROBACTER; ESCHERICHIA COLI; GENE CASSETTE; GENE SEQUENCE; GRAM NEGATIVE BACTERIUM; HORIZONTAL GENE TRANSFER; INTEGRON; KLEBSIELLA; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MYROIDES; NONHUMAN; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; PSEUDOMONAS; WASTE WATER TREATMENT PLANT; BACTERIAL GENE; BACTERIUM CONJUGATION; CLASSIFICATION; DRUG EFFECTS; FLAVOBACTERIACEAE; GAMMAPROTEOBACTERIA; GENE EXPRESSION; GENETICS; HEALTH SURVEY; HOSPITAL; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL CONSORTIUM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PORTUGAL; WASTE DISPOSAL; WASTE WATER;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CARBAPENEMS; CONJUGATION, GENETIC; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FLAVOBACTERIACEAE; GAMMAPROTEOBACTERIA; GENE EXPRESSION; GENES, BACTERIAL; HOSPITALS; HUMANS; INTEGRONS; MEDICAL WASTE DISPOSAL; MICROBIAL CONSORTIA; MICROBIAL SENSITIVITY TESTS; PORTUGAL; PUBLIC HEALTH SURVEILLANCE; QUINOLONES; WASTE WATER;

EID: 84960912246     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2015.0118     Document Type: Article

References (47)

1. Baquero, F., J. L. Martinez, and R. Canton. 2008. Antibiotics and antibiotic resistance in water environments. Curr. Opin. Biotechnol. 19:260-265.
2. Biswal, B. K., A. Mazza, L. Masson, R. Gehr, and D. Frigon. 2014. Impact of wastewater treatment processes on antimicrobial resistance genes and their co-occurrence with virulence genes in Escherichia coli. Water Res. 50:245-253.
3. Carattoli, A. 2013. Plasmids and the spread of resistance. Int. J. Med. Microbiol. 303:298-304.
4. Chandran, S. P., V. Diwan, A. J. Tamhankar, B. V. Joseph, S. Rosales-Klintz, S. Mundayoor, C. S. Lundborg, and R. Macaden. 2014. Detection of carbapenem resistance genes and cephalosporin, and quinolone resistance genes along with oqxAB gene in Escherichia coli in hospital wastewater: A matter of concern. J. Appl. Microbiol. 117:984-995.
5. [CLSI] Clinical and Laboratory Standards Institute. 2013. Performance Standards for Antimicrobial Susceptibility Testing. Twenty-Third Informational Supplement. Clinical and Laboratory Standards Institute, Wayne, PA, M100-S23.
6. Deepa, R., K. G. Venkatesh, J. D. Parveen, S. T. Banu, and G. Jayalakshmi. 2014. Myroides odoratus and Chryseobacterium indologenes: two rare isolates in the immunocompromised. Indian J. Med. Microbiol. 32:327-330.
7. Diwan, V., S. P. Chandran, A. J. Tamhankar, C. Stalsby Lundborg, and R. Macaden. 2012. Identification of extended-spectrum beta-lactamase and quinolone resistance genes in Escherichia coli isolated from hospital wastewater from central India. J. Antimicrob. Chemother. 67:857-859.
8. [ECDC] European Centre for Disease Prevention and Control. 2013. Point prevalence survey of healthcareassociated infections and antimicrobial use in European long-term care facilities. Stockholm: ECDC.
9. Ferreira da Silva, M., I. Vaz-Moreira, M. Gonzalez-Pajuelo, O. C. Nunes, and C. M. Manaia. 2007. Antimicrobial resistance patterns in Enterobacteriaceae isolated from an urban wastewater treatment plant. FEMS Microbiol. Ecol. 60:166-176.
10. Figueira, V., E. Serra, and C. M. Manaia. 2011. Differential patterns of antimicrobial resistance in population subsets of Escherichia coli isolated from waste-and surface waters. Sci. Total Environ. 409:1017-1023.
11. Figueira, V., E. A. Serra, I. Vaz-Moreira, T. R. S. Branda o, and C. M. Manaia. 2012. Comparison of ubiquitous antibiotic-resistant Enterobacteriaceae populations isolated from wastewaters, surface waters and drinking waters. J. Water Health 10:1-10.
12. Figueira, V., I. Vaz-Moreira, M. Silva, and C. M. Manaia. 2011. Diversity and antibiotic resistance of Aeromonas spp. in drinking and waste water treatment plants. Water Res. 45:5599-5611.
13. Galvin, S., F. Boyle, P. Hickey, A. Vellinga, D. Morris, and M. Cormican. 2010. Enumeration and characterization of antimicrobial-resistant Escherichia coli bacteria in effluent from municipal, hospital, and secondary treatment facility sources. Appl. Environ. Microbiol. 76:4772-4779.
14. Goni-Urriza, M.,M. Capdepuy, C. Arpin, N. Raymond, P. Caumette, and C. Quentin. 2000. Impact of an urban effluent on antibiotic resistance of riverine Enterobacteriaceae and Aeromonas spp. Appl. Environ. Microbiol. 66:125-132.
15. Guardabassi, L., A. Petersen, J. E. Olsen, and A. Dalsgaard. 1998. Antibiotic resistance in Acinetobacter spp. isolated from sewers receiving waste effluent from a hospital and a pharmaceutical plant. Appl. Environ. Microbiol. 64:3499-3502.
16. Henriques, I. S., S. Araujo, J. S. Azevedo, M. S. Alves, C. Chouchani, A. Pereira, and A. Correia. 2012. Prevalence and diversity of carbapenem-resistant bacteria in untreated drinking water in Portugal. Microb. Drug Resist. 18:531-537.
17. Henriques, I. S., F. Fonseca, A. Alves, M. J. Saavedra, and A. Correia. 2006. Occurrence and diversity of integrons and beta-lactamase genes among ampicillinresistant isolates from estuarine waters. Res. Microbiol. 157:938-947.
18. Kim, O. S., Y. J. Cho, K. Lee, S. H. Yoon, M. Kim, H. Na, S. C. Park, Y. S. Jeon, J. H. Lee, H. Yi, S. Won, and J. Chun. 2012. Introducing EzTaxon-e: A prokaryotic 16S rRNA gene sequence database with phylotypes that represent uncultured species. Int. J. Syst. Evol. Microbiol. 62:716-721.
19. Kümmerer, K. 2004. Resistance in the environment. J. Antimicrob. Chemother. 54:311-320.
20. Li, X. Z. 2005. Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms. Int. J. Antimicrob. Agents 25:453-463.
21. Liu, B. T., X. M. Wang, X. P. Liao, J. Sun, H. Q. Zhu, X. Y. Chen, and Y. H. Liu. 2011. Plasmid-mediated quinolone resistance determinants oqxAB and aac(6')-Ib-cr and extended-spectrum beta-lactamase gene blaCTX-M-24 co-located on the same plasmid in one Escherichia coli strain from China. J. Antimicrob. Chemother. 66:1638-1639.
22. Luczkiewicz, A., K. Jankowska, S. Fudala-Ksiazek, and K. Olanczuk-Neyman. 2010. Antimicrobial resistance of fecal indicators in municipal wastewater treatment plant. Water Res. 44:5089-5097.
23. Malik, A., and A. Aleem. 2011. Incidence of metal and antibiotic resistance in Pseudomonas spp. from the river water, agricultural soil irrigated with wastewater and groundwater. Environ. Monit. Assess. 178:293-308.
24. Michel, C., O. Matte-Tailliez, B. Kerouault, and J. F. Bernardet. 2005. Resistance pattern and assessment of phenicol agents' minimum inhibitory concentration in multiple drug resistant Chryseobacterium isolates from fish and aquatic habitats. J. Appl. Microbiol. 99:323-332.
25. Munir, M., K. Wong, and I. Xagoraraki. 2011. Release of antibiotic resistant bacteria and genes in the effluent and biosolids of five wastewater utilities in Michigan. Water Res. 45:681-693.
26. Narciso-da-Rocha, C., I. Vaz-Moreira, L. Svensson-Stadler, E. R. B. Moore, and C. M. Manaia. 2013. Diversity and antibiotic resistance of Acinetobacter spp. in water from the source to the tap. Appl. Microbiol. Biotechnol. 97:329-340.
27. Novo, A., S. Andre, P. Viana, O. C. Nunes, and C. M. Manaia. 2013. Antibiotic resistance, antimicrobial residues and bacterial community composition in urban wastewater. Water Res. 47:1875-1887.
28. Partridge, S. R., J. A. Ellem, S. G. Tetu, Z. Zong, I. T. Paulsen, and J. R. Iredell. 2011. Complete sequence of pJIE143, a pir-type plasmid carrying ISEcp1-blaCTX-M-15 from an Escherichia coli ST131 isolate. Antimicrob. Agents Chemother. 55:5933-5935.
29. Pauwels, B., and W. Verstraete. 2006. The treatment of hospital wastewater: An appraisal. J. Water Health 4:405-416.
30. Rizzo, L., C. Manaia, C. Merlin, T. Schwartz, C. Dagot, M. C. Ploy, I. Michael, and D. Fatta-Kassinos. 2013. Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: A review. Sci. Total Environ. 447:345-360.
31. Robicsek, A., G. A. Jacoby, and D. C. Hooper. 2006. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect. Dis. 6:629-640.
32. Schwartz, T., W. Kohnen, B. Jansen, and U. Obst. 2003. Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms. FEMS Microbiol. Ecol. 43:325-335.
33. Shi, P., S. Jia, X. X. Zhang, T. Zhang, S. Cheng, and A. Li. 2013. Metagenomic insights into chlorination effects on microbial antibiotic resistance in drinking water. Water Res. 47:111-120.
34. Skurnik, D., A. Le Menac'h, D. Zurakowski, D. Mazel, P. Courvalin, E. Denamur, A. Andremont, and R. Ruimy. 2005. Integron-associated antibiotic resistance and phylogenetic grouping of Escherichia coli isolates from healthy subjects free of recent antibiotic exposure. Antimicrob. Agents Chemother. 49:3062-3065.
35. Slekovec, C., J. Plantin, P. Cholley, M. Thouverez, D. Talon, X. Bertrand, and D. Hocquet. 2012. Tracking down antibiotic-resistant Pseudomonas aeruginosa isolates in a wastewater network. PLoS One 7:e49300.
36. Strahilevitz, J., G. A. Jacoby, D. C. Hooper, and A. Robicsek. 2009. Plasmid-mediated quinolone resistance: A multifaceted threat. Clin. Microbiol. Rev. 22:664-689.
37. Szczepanowski, R., B. Linke, I. Krahn, K. H. Gartemann, T. Gutzkow, W. Eichler, A. Puhler, and A. Schluter. 2009. Detection of 140 clinically relevant antibiotic-resistance genes in the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to selected antibiotics. Microbiology 155:2306-2319.
38. Varela, A. R., S. Andre, O. C. Nunes, and C. M. Manaia. 2014. Insights into the relationship between antimicrobial residues and bacterial populations in a hospital-urban wastewater treatment plant system. Water Res. 54:327-336.
39. Varela, A. R., G. Ferro, J. Vredenburg, M. Yanik, L. Vieira, L. Rizzo, C. Lameiras, and C. M. Manaia. 2013. Vancomycin resistant enterococci: from the hospital effluent to the urban wastewater treatment plant. Sci. Total Environ. 450:155-161.
40. Varela, A. R., G. N. Macedo, O. C. Nunes, and C. M. Manaia. 2015. Genetic characterization of fluoroquinolone resistant Escherichia coli from urban streams and municipal and hospital effluents. FEMS Microbiol. Ecol. 91. DOI: 10. 1093/femsec/fiv015.
41. Vaz-Moreira, I., O. C. Nunes, and C. M. Manaia. 2012. Diversity and antibiotic resistance in Pseudomonas spp. from drinking water. Sci. Total Environ. 426:366-374.
42. Vaz-Moreira, I., O. C. Nunes, and C. M. Manaia. 2014. Bacterial diversity and antibiotic resistance in water habitats: searching the links with the human microbiome. FEMS Microbiol. Rev. 38:761-778.
43. Vredenburg, J., A. R. Varela, B. Hasan, S. Bertilsson, B. Olsen, C. Narciso-da-Rocha, J. Bonnedahl, J. Stedt, P. M. Da Costa, and C. M. Manaia. 2014. Quinoloneresistant Escherichia coli isolated from birds of prey in Portugal are genetically distinct from those isolated from water environments and gulls in Portugal, Spain and Sweden. Environ. Microbiol. 16:995-1004.
44. Wellington, E. M., A. B. Boxall, P. Cross, E. J. Feil, W. H. Gaze, P. M. Hawkey, A. S. Johnson-Rollings, D. L. Jones, N. M. Lee, W. Otten, C. M. Thomas, and A. P. Williams. 2013. The role of the natural environment in the emergence of antibiotic resistance in gram-negative bacteria. Lancet Infect. Dis. 13:155-165.
45. Wu, J. J., W. C. Ko, S. H. Tsai, and J. J. Yan. 2007. Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital. Antimicrob. Agents Chemother. 51:1223-1227.
46. Yuan, J., X. Xu, Q. Guo, X. Zhao, X. Ye, Y. Guo, and M. Wang. 2012. Prevalence of the oqxAB gene complex in Klebsiella pneumoniae and Escherichia coli clinical isolates. J. Antimicrob. Chemother. 67:1655-1659.
47. Zhao, W. H., G. Chen, R. Ito, and Z. Q. Hu. 2009. Relevance of resistance levels to carbapenems and integronborne blaIMP-1, blaIMP-7, blaIMP-10 and blaVIM-2 in clinical isolates of Pseudomonas aeruginosa. J. Med. Microbiol. 58:1080-1085.