Prevalence of the oqxAB gene complex in Klebsiella pneumoniae and Escherichia coli clinical isolates

Journal of Antimicrobial Chemotherapy

Volumn 67, Issue 7, 2012, Pages 1655-1659

  Yuan, Jinyi ^a   Xu, Xiaogang ^a   Guo, Qinglan ^a   Zhao, Xu ^a   Ye, Xinyu ^a   Guo, Yan ^a   Wang, Minggui ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Efflux pumps; Plasmid mediated quinolone resistance; Resistance nodulation cell division family

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; LEVOFLOXACIN; MULTIPROTEIN COMPLEX; OQXA PROTEIN; OQXAB PROTEIN COMPLEX; OQXB PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE SEQUENCE; GENETIC SIMILARITY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ANTI-BACTERIAL AGENTS; CONJUGATION, GENETIC; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MEMBRANE TRANSPORT PROTEINS; POLYMERASE CHAIN REACTION; PREVALENCE; QUINOLONES;

EID: 84862675206     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks086     Document Type: Article

References (10)

1. Strahilevitz J, Jacoby GA, Hooper DC et al. Plasmid-mediated quinolone resistance: a multifaceted threat. Clin Microbiol Rev 2009; 22: 664-89.
2. Hansen LH, Johannesen E, Burmølle M et al. Plasmid-encoded multidrug efflux pump conferring resistance to olaquindox in Escherichia coli. Antimicrob Agents Chemother 2004; 48: 3332-7.
3. Sørensen AH, Hansen LH, Johannesen E et al. Conjugative plasmid conferring resistance to olaquindox. Antimicrob Agents Chemother 2003; 47: 798-9.
4. Zhao J, Chen Z, Chen S et al. Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farm workers, and the environment. Antimicrob Agents Chemother 2010; 54: 4219-24.
5. Hansen LH, Jensen LB, Sørensen HI et al. Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria. J Antimicrob Chemother 2007; 60: 145-7.
6. Norman A, Hansen LH, She Q et al. Nucleotide sequence of pOLA52: a conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux. Plasmid 2008; 60: 59-74.
7. Hansen LH, Sørensen SJ, Jørgensen HS et al. The prevalence of the OqxAB multidrug efflux pump amongst olaquindox-resistant Escherichia coli in pigs. Microb Drug Resist 2005; 11: 378-82.
8. Kim HB, Wang M, Park CH et al. oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother 2009; 53: 3582-4.
9. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Twentieth Informational Supplement M100-S20. CLSI, Wayne, PA, USA, 2010.
10. Wang M, Tran JH, Jacoby GA et al. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother 2003; 47: 2242-8.