Hypoxia/ischemia promotes CXCL10 expression in cardiac microvascular endothelial cells by NFkB activation

Cytokine

Volumn 81, Issue , 2016, Pages 63-70

  Xia, Jing Bo ^a   Liu, Guang Hui ^a   Chen, Zhuo Ying ^a   Mao, Cheng Zhou ^a   Zhou, Deng Cheng ^a   Wu, Hai Yan ^a   Park, Kyu Sang ^b   Zhao, Hui ^c   Kim, Soo Ki ^b   Cai, Dong Qing ^a   Qi, Xu Feng ^a  

^a JINAN UNIVERSITY   (China)

^b Yonsei University Wonju College of Medicine   (South Korea)

^c Prince of Wales Hospital   (Hong Kong)

Author keywords

CMECs; CXCL10; Expression; Hypoxia ischemia; NFkB

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR FKHRL1; FOXO3A PROTEIN, RAT; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BINDING SITE; CAPILLARY ENDOTHELIAL CELL; CELL HYPOXIA; CONTROLLED STUDY; CXCL10 GENE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; HEART MUSCLE CELL; MICROVASCULAR ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CORONARY BLOOD VESSEL; CYTOLOGY; ENDOTHELIUM CELL; GENE EXPRESSION; GENETICS; ISCHEMIA; METABOLISM; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; CHEMOKINE CXCL10; CORONARY VESSELS; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FORKHEAD BOX PROTEIN O3; GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISCHEMIA; NF-KAPPA B; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84960905720     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2016.02.007     Document Type: Article

References (30)

1. Sallusto F., Lenig D., Mackay C.R., Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 1998, 187:875-883.
2. Lee E.Y., Lee Z.H., Song Y.W. CXCL10 and autoimmune diseases. Autoimmun. Rev. 2009, 8:379-383.
3. Weng Y., Siciliano S.J., Waldburger K.E., Sirotina-Meisher A., Staruch M.J., Daugherty B.L., et al. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J. Biol. Chem. 1998, 273:18288-18291.
4. Luster A.D. Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 1998, 338:436-445.
5. Liu M., Guo S., Hibbert J.M., Jain V., Singh N., Wilson N.O., et al. CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications. Cytokine Growth Factor Rev. 2011, 22:121-130.
6. Bujak M., Dobaczewski M., Gonzalez-Quesada C., Xia Y., Leucker T., Zymek P., et al. Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ. Res. 2009, 105:973-983.
7. Frangogiannis N.G., Mendoza L.H., Lewallen M., Michael L.H., Smith C.W., Entman M.L. Induction and suppression of interferon-inducible protein 10 in reperfused myocardial infarcts may regulate angiogenesis. FASEB J. 2001, 15:1428-1430.
8. Eom G.H., Kim K.B., Kim J.H., Kim J.Y., Kim J.R., Kee H.J., et al. Histone methyltransferase SETD3 regulates muscle differentiation. J. Biol. Chem. 2011, 286:34733-34742.
9. van den Borne P., Haverslag R.T., Brandt M.M., Cheng C., Duckers H.J., Quax P.H., et al. Absence of chemokine (C-x-C motif) ligand 10 diminishes perfusion recovery after local arterial occlusion in mice. Arterioscler. Thromb. Vasc. Biol. 2014, 34:594-602.
10. Cao L., Zhang L., Chen S., Yuan Z., Liu S., Shen X., et al. BDNF-mediated migration of cardiac microvascular endothelial cells is impaired during ageing. J. Cell Mol. Med. 2012, 16:3105-3115.
11. Liu Y., Ma Y., Wang R., Xia C., Zhang R., Lian K., et al. Advanced glycation end products accelerate ischemia/reperfusion injury through receptor of advanced end product/nitrative thioredoxin inactivation in cardiac microvascular endothelial cells. Antioxid. Redox Signal. 2011, 15:1769-1778.
12. Das A., Smolenski A., Lohmann S.M., Kukreja R.C. Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. J. Biol. Chem. 2006, 281:38644-38652.
13. Zhang T., Yang D., Fan Y., Xie P., Li H. Epigallocatechin-3-gallate enhances ischemia/reperfusion-induced apoptosis in human umbilical vein endothelial cells via AKT and MAPK pathways. Apoptosis 2009, 14:1245-1254.
14. Qi X.F., Chen Z.Y., Xia J.B., Zheng L., Zhao H., Pi L.Q., et al. FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle. J. Mol. Cell. Cardiol. 2015, 81:114-126.
15. Brutsaert D.L. Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity. Physiol. Rev. 2003, 83:59-115.
16. Ellinsworth D.C. Arsenic, reactive oxygen, and endothelial dysfunction. J. Pharmacol. Exp. Ther. 2015, 353:458-464.
17. Gilbert R.E. Endothelial loss and repair in the vascular complications of diabetes: pathogenetic mechanisms and therapeutic implications. Circ. J. 2013, 77:849-856.
18. Hoenig M.R., Bianchi C., Rosenzweig A., Sellke F.W. The cardiac microvasculature in hypertension, cardiac hypertrophy and diastolic heart failure. Curr. Vasc. Pharmacol. 2008, 6:292-300.
19. Angiolillo A.L., Sgadari C., Taub D.D., Liao F., Farber J.M., Maheshwari S., et al. Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J. Exp. Med. 1995, 182:155-162.
20. Keane M.P., Belperio J.A., Arenberg D.A., Burdick M.D., Xu Z.J., Xue Y.Y., et al. IFN-gamma-inducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis. J. Immunol. 1999, 163:5686-5692.
21. Alves G.D., Pazzine M., de Macedo Gomes, Braga L.M., Irigoyen M.C., De Angelis K., Ikuta N., et al. Molecular mapping of the regenerative niche in a murine model of myocardial infarction. Int. J. Mol. Med. 2012, 29:479-484.
22. Zhao J., Du F., Shen G., Zheng F., Xu B. The role of hypoxia-inducible factor-2 in digestive system cancers. Cell Death Dis. 2015, 6:e1600.
23. Ichiki T., Sunagawa K. Novel roles of hypoxia response system in glucose metabolism and obesity. Trends Cardiovasc. Med. 2014, 24:197-201.
24. Qi X.F., Kim D.H., Yoon Y.S., Jin D., Huang X.Z., Li J.H., et al. Essential involvement of cross-talk between IFN-gamma and TNF-alpha in CXCL10 production in human THP-1 monocytes. J. Cell. Physiol. 2009, 220:690-697.
25. Qi X.F., Li Y.J., Chen Z.Y., Kim S.K., Lee K.J., Cai D.Q. Involvement of the FoxO3a pathway in the ischemia/reperfusion injury of cardiac microvascular endothelial cells. Exp. Mol. Pathol. 2013, 95:242-247.
26. Ong S.G., Hausenloy D.J. Hypoxia-inducible factor as a therapeutic target for cardioprotection. Pharmacol. Ther. 2012, 136:69-81.
27. Loor G., Schumacker P.T. Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Cell Death Differ. 2008, 15:686-690.
28. Burma O., Onat E., Uysal A., Ilhan N., Erol D., Ozcan M., et al. Effects of rosuvastatin on ADMA, rhokinase, NADPH oxidase, caveolin-1, hsp 90 and NFkB levels in a rat model of myocardial ischaemia-reperfusion. Cardiovasc. J. Afr. 2014, 25:212-216.
29. Ziypak T., Halici Z., Alkan E., Akpinar E., Polat B., Adanur S., et al. Renoprotective effect of aliskiren on renal ischemia/reperfusion injury in rats: electron microscopy and molecular study. Ren. Fail. 2015, 37:343-354.
30. Webster C.M., Hokari M., McManus A., Tang X.N., Ma H., Kacimi R., et al. Microglial P2Y12 deficiency/inhibition protects against brain ischemia. PLoS ONE 2013, 8:e70927.