Three-dimensional plotted hydroxyapatite scaffolds with predefined architecture: Comparison of stabilization by alginate cross-linking versus sintering

Journal of Biomaterials Applications

Volumn 30, Issue 8, 2016, Pages 1168-1181

  Kumar, Alok ^a   Akkineni, Ashwini R ^b   Basu, Bikramjit ^a   Gelinsky, Michael ^b  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

additive manufacturing; direct plotting; hydroxyapatite; rapid prototyping; robocasting; Three dimensional plotting

Indexed keywords

3D PRINTERS; ALGINATE; BINDERS; BINS; BONE; CELL ENGINEERING; CELL PROLIFERATION; COMPRESSIVE STRENGTH; CROSSLINKING; HYDROXYAPATITE; MANUFACTURE; POLYSACCHARIDES; RAPID PROTOTYPING; SINTERING; SODIUM; SODIUM ALGINATE; STABILIZATION; TISSUE; TISSUE ENGINEERING;

BONE TISSUE ENGINEERING; CHEMICAL STABILIZATION; DIRECT PLOTTING; EXTRACELLULAR MATRICES; PROGRESSIVE DEFORMATION; ROBOCASTING; THREE-DIMENSIONAL POROUS SCAFFOLDS; THREE-DIMENSIONAL STRUCTURE;

SCAFFOLDS (BIOLOGY);

ALGINIC ACID; HYDROXYAPATITE; MALTODEXTRIN; MOLECULAR SCAFFOLD; CALCIUM CHLORIDE; CROSS LINKING REAGENT; GLUCURONIC ACID; HEXURONIC ACID;

ARTICLE; CHEMICAL PROCEDURES; COMPARATIVE STUDY; COMPRESSIVE STRENGTH; CONTROLLED STUDY; CROSS LINKING; MOLECULAR STABILITY; POROSITY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SINTERING; STRUCTURE ANALYSIS; CHEMISTRY; MATERIALS TESTING; PROCEDURES; TISSUE ENGINEERING; TISSUE SCAFFOLD;

ALGINATES; CALCIUM CHLORIDE; COMPRESSIVE STRENGTH; CROSS-LINKING REAGENTS; DURAPATITE; GLUCURONIC ACID; HEXURONIC ACIDS; MATERIALS TESTING; POROSITY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84960847710     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328215617058     Document Type: Article

References (30)

1. Rho JY, Kuhn-Spearing L, Zioupos P,. Mechanical properties and the hierarchical structure of bone. Med Eng Phys 1998; 20: 92-102.
2. Murugan R, Ramakrishna S,. Development of nanocomposites for bone grafting. Compos Sci Technol 2005; 65: 2385-2406.
3. Dorozhkin S,. Calcium orthophosphate-based bioceramics. Materials (Basel) 2013; 6: 3840-3942.
4. Kumar A, Biswas K, Basu B,. Hydroxyapatite-titanium bulk composites for bone tissue engineering applications. J Biomed Mater Res A 2014; 103: 791-806.
5. Kumar A, Biswas K, Basu B,. On the toughness enhancement in hydroxyapatite-based composites. Acta Mater 2013; 61: 5198-5215.
6. Feng B, Jinkang Z, Zhen W, et al. The effect of pore size on tissue ingrowth and neovascularization in porous bioceramics of controlled architecture in vivo. Biomed Mater 2011; 6: 015007-015007.
7. Fulmer MT, Ison IC, Hankermayer CR, et al. Measurements of the solubilities and dissolution rates of several hydroxyapatites. Biomaterials 2002; 23: 751-755.
8. Karageorgiou V, Kaplan D,. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 2005; 26: 5474-5491.
9. Vasireddi R and Basu B. Conceptual design of three-dimensional scaffolds of powder-based materials for bone tissue engineering applications. Rapid Prototyp J. Epub ahead of print 2015. DOI: 10.1108/RPJ-12-2013-0123.
10. Lode A, Meissner K, Luo Y, et al. Fabrication of porous scaffolds by three-dimensional plotting of a pasty calcium phosphate bone cement under mild conditions. J Tissue Eng Regen Med 2014; 8: 682-693.
11. Castilho M, Dias M, Gbureck U,. Fabrication of computationally designed scaffolds by low temperature 3D printing. Biofabrication 2013; 66: 911-917.
12. Klammert U, Gbureck U, Vorndran E, et al. 3D powder printed calcium phosphate implants for reconstruction of cranial and maxillofacial defects. J Craniomaxillofac Surg 2010; 38: 565-570.
13. Chumnanklang R, Panyathanmaporn T, Sitthiseripratip K, et al. 3D printing of hydroxyapatite: effect of binder concentration in pre-coated particle on part strength. Mater Sci Eng C 2007; 27: 914-921.
14. Luo Y, Lode A, Sonntag F, et al. Well-ordered biphasic calcium phosphate-alginate scaffolds fabricated by multi-channel 3D plotting under mild conditions. J Mater Chem B 2013; 1: 4088-4098.
15. Landers R, Hübner U, Schmelzeisen R, et al. Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering. Biomaterials 2002; 23: 4437-4447.
16. Luo Y, Akkineni AR, Gelinsky M,. Three-dimensional plotting is a versatile rapid prototyping method for the customized manufacturing of complex scaffolds and tissue engineering constructs. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2014; 28: 279-285.
17. Bajaj P, Schweller RM, Khademhosseini A, et al. 3D biofabrication strategies for tissue engineering and regenerative medicine. Annu Rev Biomed Eng 2014; 16: 247-276.
18. Akkineni AR, Luo Y, Schumacher M, et al. 3D plotting of growth factor loaded calcium phosphate cement scaffolds. Acta Biomater 2015; 27: 264-274.
19. Miranda P, Saiz E, Gryn K, et al. Sintering and robocasting of beta-tricalcium phosphate scaffolds for orthopaedic applications. Acta Biomater 2006; 2: 457-466.
20. Dellinger JG, Cesarano J, Jamison RD,. Robotic deposition of model hydroxyapatite scaffolds with multiple architectures and multiscale porosity for bone tissue engineering. J Biomed Mater Res A 2007; 82A: 383-394.
21. Saiz E, Gremillard L, Menendez G, et al. Preparation of porous hydroxyapatite scaffolds. Mater Sci Eng C 2007; 27: 546-550.
22. Houmard M, Fu Q, Genet M, et al. On the structural, mechanical, and biodegradation properties of HA/β-TCP robocast scaffolds. J Biomed Mater Res B Appl Biomater 2013; 101: 1233-1242.
23. Wu C, Fan W, Zhou Y, et al. 3D-printing of highly uniform CaSiO3 ceramic scaffolds: preparation, characterization and in vivo osteogenesis. J Mater Chem 2012; 22: 12288-12295.
24. Miranda P, Pajares A, Saiz E, et al. Fracture modes under uniaxial compression in hydroxyapatite scaffolds fabricated by robocasting. J Biomed Mater Res A 2007; 83: 646-655.
25. Miranda P, Pajares A, Saiz E, et al. Mechanical properties of calcium phosphate scaffolds fabricated by robocasting. J Biomed Mater Res Part A 2008; 85: 218-227.
26. Franco J, Hunger P, Launey M, et al. Direct write assembly of calcium phosphate scaffolds using a water-based hydrogel. Acta Biomater 2010; 6: 218-228.
27. Maazouz Y, Montufar EB, Guillem-Marti J, et al. Robocasting of biomimetic hydroxyapatite scaffolds using self-setting inks. J Mater Chem B 2014; 2: 5378-5386.
28. Webster TJ, Ergun C, Doremus RH, et al. Enhanced functions of osteoblasts on nanophase ceramics. Biomaterials 2000; 21: 1803-1810.
29. Kang S-JL,. Sintering: densification, grain growth and microstructure, Oxford, UK: Elsevier Butterworth-Heinemann, 2004.
30. Chanda A, SinghaRoy R, Xue W,. Bone cell materials interaction on alumina ceramics with different grain sizes. Mater Sci Eng C 2009; 29: 1201-1206.