3D plotting of growth factor loaded calcium phosphate cement scaffolds

Acta Biomaterialia

Volumn 27, Issue , 2015, Pages 264-274

  Akkineni, Ashwini Rahul ^a   Luo, Yongxiang ^a,b   Schumacher, Matthias ^a   Nies, Berthold ^c   Lode, Anja ^a   Gelinsky, Michael ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b SHANGHAI INSTITUTE OF CERAMICS   (China)

^c InnoTERE GmbH   (Germany)

Author keywords

3D printing; Additive manufacturing; Calcium phosphate cement; Cement setting; Drug delivery

Indexed keywords

BIOMECHANICS; BODY FLUIDS; CALCIUM PHOSPHATE; CARTILAGE; CELL CULTURE; CELL ENGINEERING; CEMENTS; CONTROLLED DRUG DELIVERY; ENDOTHELIAL CELLS; FABRICATION; PROTEINS; SCAFFOLDS (BIOLOGY); SOLUTIONS; STEM CELLS; SULFUR COMPOUNDS; SURFACE TOPOGRAPHY; TARGETED DRUG DELIVERY;

3-D PRINTING; 3D-PRINTING; BIOLOGICAL COMPONENTS; CALCIUM PHOSPHATE CEMENT; CEMENT PASTE; CEMENT SETTINGS; CONDITION; GEOMETRICAL FEATURES; GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR;

3D PRINTERS;

BONE CEMENT; BOVINE SERUM ALBUMIN; CALCIUM PHOSPHATE; CHITOSAN; DEXTRAN SULFATE; GROWTH FACTOR; MOLECULAR SCAFFOLD; VASCULOTROPIN; WATER; BONE PROSTHESIS; DRUG IMPLANT; NANOCAPSULE; SIGNAL PEPTIDE;

AQUEOUS SOLUTION; ARTICLE; ATMOSPHERE; BIOCHEMICAL ANALYSIS; BIOCOMPATIBILITY; BIOLOGICAL ACTIVITY; BONE DEVELOPMENT; CELL CULTURE; CELL PROLIFERATION; COMPRESSION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENCAPSULATION; ENDOTHELIUM CELL; FEASIBILITY STUDY; FREEZE DRYING; HOSPITAL SERVICE; HUMAN; HUMAN CELL; HUMIDITY; IMMERSION; LEACHING; MECHANICS; MESENCHYMAL STEM CELL; MICROENCAPSULATION; PASTE; POROSITY; PRIORITY JOURNAL; PROTEIN SECRETION; SURFACE PROPERTY; TOPOGRAPHY; X RAY DIFFRACTION; ADMINISTRATION AND DOSAGE; BONE PROSTHESIS; CHEMISTRY; DEVICE FAILURE ANALYSIS; DIFFUSION; DRUG IMPLANT; INJECTION; MATERIALS TESTING; PROSTHESIS DESIGN; THREE DIMENSIONAL PRINTING; TISSUE SCAFFOLD; ULTRASTRUCTURE;

BONE CEMENTS; BONE SUBSTITUTES; CALCIUM PHOSPHATES; DIFFUSION; DRUG IMPLANTS; EQUIPMENT FAILURE ANALYSIS; INJECTIONS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATERIALS TESTING; NANOCAPSULES; POROSITY; PRINTING, THREE-DIMENSIONAL; PROSTHESIS DESIGN; TISSUE SCAFFOLDS;

EID: 84944274278     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.08.036     Document Type: Article

References (42)

1. M. Bohner, and G. Baroud Injectability of calcium phosphate pastes Biomaterials 26 2005 1553 1563
2. S. Larsson, and T.W. Bauer Use of injectable calcium phosphate cement for fracture fixation: a review Clin. Orthop. Relat. Res. 395 2002 23 32
3. A.J. Ambard, and L. Mueninghoff Calcium phosphate cement: review of mechanical and biological properties J. Prosthodont. 15 2006 321 328
4. M.P. Ginebra Cement as bone repair materials J.A. Planell, S.M. Best, D. Lacroix, A. Merolli, Bone Repair Biomaterials 2009 Woodhead Publishing Series in Biomaterials Elsevier 271 308
5. M. Bohner Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements Injury 31 2000 37 47
6. S.V. Dorozhkin Calcium orthophosphate cements for biomedical application J. Mater. Sci. 43 2008 3028 3057
7. F.C. Driessens, J. Planell, M.G. Boltong, I. Khairoun, and M.P. Ginebra Osteotransductive bone cements Proc. Inst. Mech. Eng. H 212 1998 427 435
8. S. Heinemann, S. Rössler, M. Lemm, M. Ruhnow, and B. Nies Properties of injectable ready-to-use calcium phosphate cement based on water-immiscible liquid Acta Biomater. 9 2013 6199 6207
9. A. Lode, K. Meissner, Y. Luo, F. Sonntag, S. Glorius, B. Nies, C. Vater, F. Despang, T. Hanke, and M. Gelinsky Fabrication of porous scaffolds by three-dimensional plotting of a pasty calcium phosphate bone cement under mild conditions J. Tissue Eng. Regen. Med. 8 2014 682 693
10. A. Pfister, R. Landers, A. Laib, and R. Schmelzeisen Biofunctional rapid prototyping for tissue engineering applications: 3D bioplotting versus 3D printing J. Polym. Sci. A Polym. Chem. 42 2003 624 638
11. D.W. Hutmacher, M. Sittinger, and M.V. Risbud Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems Trends Biotechnol. 22 2004 354 362
12. S. Dorozhkin Bioceramics of calcium orthophosphates Biomaterials 31 2010 1465 1485
13. H. Liao, X.F. Walboomers, W.J.E.M. Habraken, Z. Zhang, Y. Li, D.W. Grijpma, and et al. Injectable calcium phosphate cement with PLGA, gelatin and PTMC microspheres in a rabbit femoral defect Acta Biomater. 7 2011 1752 1759
14. M. Lopez-Heredia, K. Sariibrahimoglu, W. Yang, M. Bohner, D. Yamashita, A. Kunstar, and et al. Influence of the pore generator on the evolution of the mechanical properties and the porosity and interconnectivity of a calcium phosphate cement Acta Biomater. 8 2012 404 414
15. K. Lee, M.D. Weir, E. Lippens, M. Mehta, P. Wang, G.N. Duda, and et al. Bone regeneration via novel macroporous CPC scaffolds in critical-sized cranial defects in rats Dent. Mater. 30 2014 e199 e207
16. R. Landers, and R. Mülhaupt Desktop manufacturing of complex objects, prototypes and biomedical scaffolds by means of computer-assisted design combined with computer-guided 3D plotting of polymers and reactive oligomers Macromol. Mater. Eng. 282 2000 17 21
17. E. Sachs, M. Cima, J. Cornie, D. Brancazio, J. Bredt, A. Curodeau, and et al. Three-dimensional printing: the physics and implications of additive manufacturing CIRP Ann. Manuf. Technol. 42 1993 257 260
18. H. Seitz, W. Rieder, S. Irsen, B. Leukers, and C. Tille Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering J. Biomed. Mater. Res. B Appl. Biomater. 74 2005 782 788
19. U. Gbureck, E. Vorndran, F. Müller, and J.E. Barralet Low temperature direct 3D printed bioceramics and biocomposites as drug release matrices J. Control. Release 122 2007 173 180
20. U. Gbureck, T. Hölzel, I. Biermann, J.E. Barralet, and L.M. Grover Preparation of tricalcium phosphate/calcium pyrophosphate structures via rapid prototyping J. Mater. Sci. Mater. Med. 19 2008 1559 1563
21. P. Miranda, E. Saiz, K. Gryn, and A.P. Tomsia Sintering and robocasting of beta-tricalcium phosphate scaffolds for orthopaedic applications Acta Biomater. 2 2006 457 466
22. P. Miranda, A. Pajares, E. Saiz, A.P. Tomsia, and F. Guiberteau Fracture modes under uniaxial compression in hydroxyapatite scaffolds fabricated by robocasting J. Biomed. Mater. Res. A 83 2007 646 655
23. J. Franco, P. Hunger, M.E. Launey, A.P. Tomsia, and E. Saiz Direct write assembly of calcium phosphate scaffolds using a water-based hydrogel Acta Biomater. 6 2010 218 228
24. C.J.D. Bergmann, J.C.E. Odekerken, T.J.M. Welting, F. Jungwirth, D. Devine, L. Bouré, S. Zeiter, L.W. van Rhijn, R. Telle, H. Fischer, and P.J. Emans Calcium phosphate based three-dimensional cold plotted bone scaffolds for critical size bone defects BioMed. Res. Int. 2014 2014 Article ID 852610, 10 pages
25. Y. Luo, A. Lode, F. Sonntag, B. Nies, and M. Gelinsky Well-ordered biphasic calcium phosphate-alginate scaffolds fabricated by multi-channel 3D plotting under mild conditions J. Mater. Chem. B 1 2013 4088
26. A. des Rieux, B. Ucakar, B.P.K. Mupendwa, D. Colau, O. Feron, P. Carmeliet, and et al. 3D systems delivering VEGF to promote angiogenesis for tissue engineering J. Control. Release 150 2011 272 278
27. S. Knaack, A. Lode, B. Hoyer, A. Rösen-Wolff, A. Gabrielyan, I. Roeder, and M. Gelinsky Heparin modification of a biomimetic bone matrix for controlled release of VEGF J. Biomed. Mater. Res. A 102 2014 3500 3511
28. M.P. Ginebra, C. Canal, M. Espanol, D. Pastorino, and E.B. Montufar Calcium phosphate cements as drug delivery materials Adv. Drug Deliv. Rev. 64 2012 1090 1110
29. F.C.J. van de Watering, J.D.M. Molkenboer-Kuenen, O.C. Boerman, J.J.J.P. van den Beucken, and J.A. Jansen Differential loading methods for BMP-2 within injectable calcium phosphate cement J. Control. Release 164 2012 283 290
30. Y. Xiao, Q. Yin, L. Wang, and C. Bao Macro-porous calcium phosphate scaffold with collagen and growth factors for periodontal bone regeneration in dogs Ceram. Int. 41 2015 995 1003
31. A. Lode, C. Wolf-Brandstetter, A. Reinstorf, A. Bernhardt, U. König, W. Pompe, and M. Gelinsky Calcium phosphate bone cements, functionalized with VEGF: release kinetics and biological activity J. Biomed. Mater. Res. A 81 2007 474 483
32. W.J.E.M. Habraken, O.C. Boerman, J.G.C. Wolke, A.G. Mikos, and J.A. Jansen In vitro growth factor release from injectable calcium phosphate cements containing gelatin microspheres J. Biomed. Mater. Res. A 91A 2009 614 622
33. R.P. Félix Lanao, R. Bosco, S.C.G. Leeuwenburgh, M.J.F. Kersten-Niessen, J.G.C. Wolke, J.J.J.P. van den Beucken, and et al. RANKL delivery from calcium phosphate containing PLGA microspheres J. Biomed. Mater. Res. A 101 2013 3123 3130
34. E.J. Blom, J. Klein-Nulend, C.P. Klein, K. Kurashina, M. van Waas, and E.H. Burger Transforming growth factor-beta1 incorporated during setting in calcium phosphate cement stimulates bone cell differentiation in vitro J. Biomed. Mater. Res. 50 2000 67 74
35. E. Vorndran, M. Geffers, A. Ewald, M. Lemm, B. Nies, and U. Gbureck Ready-to-use injectable calcium phosphate bone cement paste as drug carrier Acta Biomater. 9 2013 9558 9567
36. M. Huang, S.N. Vitharana, L.J. Peek, T. Coop, and C. Berkland Polyelectrolyte complexes stabilize and controllably release vascular endothelial growth factor Biomacromolecules 8 2007 1607 1614
37. M. Schumacher, A. Henß, M. Rohnke, and M. Gelinsky A novel and easy-to-prepare strontium(II) modified calcium phosphate bone cement with enhanced mechanical properties Acta Biomater. 9 2013 7536 7544
38. M.P. Ginebra, T. Traykova, and J.A. Planell Calcium phosphate cements as bone drug delivery systems: a review J. Control. Release 113 2006 102 110
39. S. Bose, and S. Tarafder Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review Acta Biomater. 8 2012 1401 1421
40. H.W. Kim, J.C. Knowles, and H.E. Kim Hydroxyapatite/poly(ε-caprolactone) composite coatings on hydroxyapatite porous bone scaffold for drug delivery Biomaterials 25 2004 1279 1287
41. W. Xue, A. Bandyopadhyay, and S. Bose Polycaprolactone coated porous tricalcium phosphate scaffolds for controlled release of protein for tissue engineering J. Biomed. Mater. Res. B Appl. Biomater. 91 2009 831 838
42. Y. Fu, and W.J. Kao Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems Expert Opin. Drug Deliv. 7 2010 429 444