-
1
-
-
84903885666
-
Regulation of adipocyte lipolysis
-
Fruhbeck G, Mendez-Gimenez L, Fernandez-Formoso JA, Fernandez S, Rodriguez A. Regulation of adipocyte lipolysis. Nutr Res Rev 2014; 27: 63-93.
-
(2014)
Nutr Res Rev
, vol.27
, pp. 63-93
-
-
Fruhbeck, G.1
Mendez-Gimenez, L.2
Fernandez-Formoso, J.A.3
Fernandez, S.4
Rodriguez, A.5
-
2
-
-
84930970521
-
Targeting adipose tissue lipid metabolism to improve glucose metabolism in cardiometabolic disease
-
Jocken JWE, Goossens GH, Blaak EE. Targeting adipose tissue lipid metabolism to improve glucose metabolism in cardiometabolic disease. EMJ Diabet 2014; 2: 73-82.
-
(2014)
EMJ Diabet
, vol.2
, pp. 73-82
-
-
Jocken, J.W.E.1
Goossens, G.H.2
Blaak, E.E.3
-
3
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPARalpha and PGC-1
-
Haemmerle G, Moustafa T, Woelkart G, Buttner S, Schmidt A, van de Weijer T, et al. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPARalpha and PGC-1. Nat Med 2011; 17: 1076-1085.
-
(2011)
Nat Med
, vol.17
, pp. 1076-1085
-
-
Haemmerle, G.1
Moustafa, T.2
Woelkart, G.3
Buttner, S.4
Schmidt, A.5
Van De Weijer, T.6
-
4
-
-
84864098852
-
Lipolytic products activate peroxisome proliferator-Activated receptor (PPAR) alpha and delta in brown adipocytes to match fatty acid oxidation with supply
-
Mottillo EP, Bloch AE, Leff T, Granneman JG. Lipolytic products activate peroxisome proliferator-Activated receptor (PPAR) alpha and delta in brown adipocytes to match fatty acid oxidation with supply. J Biol Chem 2012; 287: 25038-25048.
-
(2012)
J Biol Chem
, vol.287
, pp. 25038-25048
-
-
Mottillo, E.P.1
Bloch, A.E.2
Leff, T.3
Granneman, J.G.4
-
5
-
-
68549135297
-
Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: Evidence from mice lacking HSL
-
Strom K, Gundersen TE, Hansson O, Lucas S, Fernandez C, Blomhoff R, et al. Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL. FASEB J 2009; 23: 2307-2316.
-
(2009)
FASEB J
, vol.23
, pp. 2307-2316
-
-
Strom, K.1
Gundersen, T.E.2
Hansson, O.3
Lucas, S.4
Fernandez, C.5
Blomhoff, R.6
-
6
-
-
0344667491
-
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormonesensitive lipase-Deficient white adipose tissue
-
Zimmermann R, Haemmerle G, Wagner EM, Strauss JG, Kratky D, Zechner R. Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormonesensitive lipase-Deficient white adipose tissue. J Lipid Res 2003; 44: 2089-2099.
-
(2003)
J Lipid Res
, vol.44
, pp. 2089-2099
-
-
Zimmermann, R.1
Haemmerle, G.2
Wagner, E.M.3
Strauss, J.G.4
Kratky, D.5
Zechner, R.6
-
7
-
-
42949088997
-
The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance
-
Goossens GH. The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance. Physiol Behav 2008; 94: 206-218.
-
(2008)
Physiol Behav
, vol.94
, pp. 206-218
-
-
Goossens, G.H.1
-
8
-
-
84897366439
-
Multiple adipose depots increase cardiovascular risk via local and systemic effects
-
Karastergiou K, Fried SK. Multiple adipose depots increase cardiovascular risk via local and systemic effects. Curr Atheroscler Rep 2013; 15: 361.
-
(2013)
Curr Atheroscler Rep
, vol.15
, pp. 361
-
-
Karastergiou, K.1
Fried, S.K.2
-
9
-
-
80053408094
-
Fatty acids, obesity, and insulin resistance: Time for a reevaluation
-
Karpe F, Dickmann JR, Frayn KN. Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 2011; 60: 2441-2449.
-
(2011)
Diabetes
, vol.60
, pp. 2441-2449
-
-
Karpe, F.1
Dickmann, J.R.2
Frayn, K.N.3
-
10
-
-
37549042471
-
Effect of beta-Adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men
-
Jocken JW, Goossens GH, van Hees AM, Frayn KN, van Baak M, Stegen J, et al. Effect of beta-Adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men. Diabetologia 2008; 51: 320-327.
-
(2008)
Diabetologia
, vol.51
, pp. 320-327
-
-
Jocken, J.W.1
Goossens, G.H.2
Van Hees, A.M.3
Frayn, K.N.4
Van Baak, M.5
Stegen, J.6
-
11
-
-
34347219137
-
Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state
-
Jocken JW, Langin D, Smit E, Saris WH, Valle C, Hul GB, et al. Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. J Clin Endocrinol Metab 2007; 92: 2292-2299.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2292-2299
-
-
Jocken, J.W.1
Langin, D.2
Smit, E.3
Saris, W.H.4
Valle, C.5
Hul, G.B.6
-
12
-
-
78751534190
-
Downregulation of adipose tissue fatty acid trafficking in obesity: A driver for ectopic fat deposition?
-
McQuaid SE, Hodson L, Neville MJ, Dennis AL, Cheeseman J, Humphreys SM, et al. Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? Diabetes 2011; 60: 47-55.
-
(2011)
Diabetes
, vol.60
, pp. 47-55
-
-
McQuaid, S.E.1
Hodson, L.2
Neville, M.J.3
Dennis, A.L.4
Cheeseman, J.5
Humphreys, S.M.6
-
13
-
-
30744477567
-
Adipocyte lipases and defect of lipolysis in human obesity
-
Langin D, Dicker A, Tavernier G, Hoffstedt J, Mairal A, Ryden M, et al. Adipocyte lipases and defect of lipolysis in human obesity. Diabetes 2005; 54: 3190-3197.
-
(2005)
Diabetes
, vol.54
, pp. 3190-3197
-
-
Langin, D.1
Dicker, A.2
Tavernier, G.3
Hoffstedt, J.4
Mairal, A.5
Ryden, M.6
-
14
-
-
84899489259
-
Lipolysis in lipid turnover, cancer cachexia, and obesityinduced insulin resistance
-
Arner P, Langin D. Lipolysis in lipid turnover, cancer cachexia, and obesityinduced insulin resistance. Trends Endocrinol Metab 2014; 25: 255-262.
-
(2014)
Trends Endocrinol Metab
, vol.25
, pp. 255-262
-
-
Arner, P.1
Langin, D.2
-
15
-
-
84859631366
-
Adipocyte lipases and lipid droplet-Associated proteins: Insight from transgenic mouse models
-
Girousse A, Langin D. Adipocyte lipases and lipid droplet-Associated proteins: insight from transgenic mouse models. Int J Obes (Lond) 2012; 36: 581-594.
-
(2012)
Int J Obes (Lond
, vol.36
, pp. 581-594
-
-
Girousse, A.1
Langin, D.2
-
16
-
-
67650522935
-
Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes
-
Bezaire V, Mairal A, Ribet C, Lefort C, Girousse A, Jocken J, et al. Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes. J Biol Chem 2009; 284: 18282-18291.
-
(2009)
J Biol Chem
, vol.284
, pp. 18282-18291
-
-
Bezaire, V.1
Mairal, A.2
Ribet, C.3
Lefort, C.4
Girousse, A.5
Jocken, J.6
-
17
-
-
84912117473
-
Fatty acid chain length and saturation influences PPARalpha transcriptional activation and repression in HepG2 cells
-
Popeijus HE, van Otterdijk SD, van der Krieken SE, Konings M, Serbonij K, Plat J, et al. Fatty acid chain length and saturation influences PPARalpha transcriptional activation and repression in HepG2 cells. Mol Nutr Food Res 2014; 58: 2342-2349.
-
(2014)
Mol Nutr Food Res
, vol.58
, pp. 2342-2349
-
-
Popeijus, H.E.1
Van Otterdijk, S.D.2
Van Der Krieken, S.E.3
Konings, M.4
Serbonij, K.5
Plat, J.6
-
18
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957; 226: 497-509.
-
(1957)
J Biol Chem
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
19
-
-
84890120647
-
Insulinmediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance
-
Jocken JW, Goossens GH, Boon H, Mason RR, Essers Y, Havekes B, et al. Insulinmediated suppression of lipolysis in adipose tissue and skeletal muscle of obese type 2 diabetic men and men with normal glucose tolerance. Diabetologia 2013; 56: 2255-2265.
-
(2013)
Diabetologia
, vol.56
, pp. 2255-2265
-
-
Jocken, J.W.1
Goossens, G.H.2
Boon, H.3
Mason, R.R.4
Essers, Y.5
Havekes, B.6
-
20
-
-
0014578265
-
The kinetic properties of citrate synthase from rat liver mitochondria
-
Shepherd D, Garland PB. The kinetic properties of citrate synthase from rat liver mitochondria. Biochem J 1969; 114: 597-610.
-
(1969)
Biochem J
, vol.114
, pp. 597-610
-
-
Shepherd, D.1
Garland, P.B.2
-
21
-
-
33846029180
-
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
-
Schweiger M, Schreiber R, Haemmerle G, Lass A, Fledelius C, Jacobsen P, et al. Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem 2006; 281: 40236-40241.
-
(2006)
J Biol Chem
, vol.281
, pp. 40236-40241
-
-
Schweiger, M.1
Schreiber, R.2
Haemmerle, G.3
Lass, A.4
Fledelius, C.5
Jacobsen, P.6
-
22
-
-
0037085450
-
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
-
Haemmerle G, Zimmermann R, Hayn M, Theussl C, Waeg G, Wagner E, et al. Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem 2002; 277: 4806-4815.
-
(2002)
J Biol Chem
, vol.277
, pp. 4806-4815
-
-
Haemmerle, G.1
Zimmermann, R.2
Hayn, M.3
Theussl, C.4
Waeg, G.5
Wagner, E.6
-
23
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999; 98: 115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
-
24
-
-
84893740957
-
Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size
-
Yin X, Lanza IR, Swain JM, Sarr MG, Nair KS, Jensen MD. Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size. J Clin Endocrinol Metab 2014; 99: E209-E216.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E209-E216
-
-
Yin, X.1
Lanza, I.R.2
Swain, J.M.3
Sarr, M.G.4
Nair, K.S.5
Jensen, M.D.6
-
25
-
-
77957562729
-
Acute stimulation of white adipocyte respiration by PKA-induced lipolysis
-
Yehuda-Shnaidman E, Buehrer B, Pi J, Kumar N, Collins S. Acute stimulation of white adipocyte respiration by PKA-induced lipolysis. Diabetes 2010; 59: 2474-2483.
-
(2010)
Diabetes
, vol.59
, pp. 2474-2483
-
-
Yehuda-Shnaidman, E.1
Buehrer, B.2
Pi, J.3
Kumar, N.4
Collins, S.5
-
26
-
-
34247342582
-
Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-Activated receptor alpha deficiency
-
Walker CG, Holness MJ, Gibbons GF, Sugden MC. Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-Activated receptor alpha deficiency. Int J Obes (Lond) 2007; 31: 1165-1171.
-
(2007)
Int J Obes (Lond
, vol.31
, pp. 1165-1171
-
-
Walker, C.G.1
Holness, M.J.2
Gibbons, G.F.3
Sugden, M.C.4
-
27
-
-
19944403543
-
Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue
-
Maeda N, Funahashi T, Hibuse T, Nagasawa A, Kishida K, Kuriyama H, et al. Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue. Proc Natl Acad Sci USA 2004; 101: 17801-17806.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17801-17806
-
-
Maeda, N.1
Funahashi, T.2
Hibuse, T.3
Nagasawa, A.4
Kishida, K.5
Kuriyama, H.6
-
28
-
-
84874692963
-
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass
-
Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, et al. Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. PLoS Biol 2013; 11: e1001485.
-
(2013)
PLoS Biol
, vol.11
, pp. e1001485
-
-
Girousse, A.1
Tavernier, G.2
Valle, C.3
Moro, C.4
Mejhert, N.5
Dinel, A.L.6
-
29
-
-
84864153448
-
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; Lower lipolysis rate despite an increased level of adipose triglyceride lipase
-
Bakke SS, Moro C, Nikolic N, Hessvik NP, Badin PM, Lauvhaug L, et al. Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase. Biochim Biophys Acta 2012; 1821: 1323-1333.
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 1323-1333
-
-
Bakke, S.S.1
Moro, C.2
Nikolic, N.3
Hessvik, N.P.4
Badin, P.M.5
Lauvhaug, L.6
-
30
-
-
84874759915
-
Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy
-
van de Weijer T, Havekes B, Bilet L, Hoeks J, Sparks L, Bosma M, et al. Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy. Circ Res 2013; 112: e51-E54.
-
(2013)
Circ Res
, vol.112
, pp. e51-E54
-
-
Van De Weijer, T.1
Havekes, B.2
Bilet, L.3
Hoeks, J.4
Sparks, L.5
Bosma, M.6
-
31
-
-
0036068739
-
Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose
-
Smih F, Rouet P, Lucas S, Mairal A, Sengenes C, Lafontan M, et al. Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose. Diabetes 2002; 51: 293-300.
-
(2002)
Diabetes
, vol.51
, pp. 293-300
-
-
Smih, F.1
Rouet, P.2
Lucas, S.3
Mairal, A.4
Sengenes, C.5
Lafontan, M.6
-
32
-
-
33745849713
-
The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-Alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma
-
Kim JY, Tillison K, Lee JH, Rearick DA, Smas CM. The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-Alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma. Am J Physiol Endocrinol Metab 2006; 291: E115-E127.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E115-E127
-
-
Kim, J.Y.1
Tillison, K.2
Lee, J.H.3
Rearick, D.A.4
Smas, C.M.5
-
33
-
-
33644764922
-
Adipose triglyceride lipase: Function, regulation by insulin, and comparison with adiponutrin
-
Kershaw EE, Hamm JK, Verhagen LA, Peroni O, Katic M, Flier JS. Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin. Diabetes 2006; 55: 148-157.
-
(2006)
Diabetes
, vol.55
, pp. 148-157
-
-
Kershaw, E.E.1
Hamm, J.K.2
Verhagen, L.A.3
Peroni, O.4
Katic, M.5
Flier, J.S.6
-
34
-
-
23644436551
-
Isoproterenol TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes
-
Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M, et al. Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes. Mol Cell Endocrinol 2005; 240: 43-49.
-
(2005)
Mol Cell Endocrinol
, vol.240
, pp. 43-49
-
-
Kralisch, S.1
Klein, J.2
Lossner, U.3
Bluher, M.4
Paschke, R.5
Stumvoll, M.6
-
35
-
-
0029983591
-
Carbohydrate metabolism in insulin resistance: Glucose uptake and lactate production by adipose and forearm tissues in vivo before and after a mixed meal
-
Coppack SW, Fisher RM, Humphreys SM, Clark ML, Pointon JJ, Frayn KN. Carbohydrate metabolism in insulin resistance: glucose uptake and lactate production by adipose and forearm tissues in vivo before and after a mixed meal. Clin Sci (Lond) 1996; 90: 409-415.
-
(1996)
Clin Sci (Lond
, vol.90
, pp. 409-415
-
-
Coppack, S.W.1
Fisher, R.M.2
Humphreys, S.M.3
Clark, M.L.4
Pointon, J.J.5
Frayn, K.N.6
-
36
-
-
0035113719
-
Whole-body and adipose tissue glucose metabolism in response to short-Term fasting in lean and obese women
-
Horowitz JF, Coppack SW, Klein S. Whole-body and adipose tissue glucose metabolism in response to short-Term fasting in lean and obese women. Am J Clin Nutr 2001; 73: 517-522.
-
(2001)
Am J Clin Nutr
, vol.73
, pp. 517-522
-
-
Horowitz, J.F.1
Coppack, S.W.2
Klein, S.3
-
37
-
-
84902159389
-
Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes
-
Albert JS, Yerges-Armstrong LM, Horenstein RB, Pollin TI, Sreenivasan UT, Chai S, et al. Null mutation in hormone-sensitive lipase gene and risk of type 2 diabetes. N Engl J Med 2014; 370: 2307-2315.
-
(2014)
N Engl J Med
, vol.370
, pp. 2307-2315
-
-
Albert, J.S.1
Yerges-Armstrong, L.M.2
Horenstein, R.B.3
Pollin, T.I.4
Sreenivasan, U.T.5
Chai, S.6
|