Exploration of the protein requirement during weight loss in obese older adults

Clinical Nutrition

Volumn 35, Issue 2, 2016, Pages 394-398

  Weijs, Peter J M ^a,b   Wolfe, Robert R ^c  

^a AMSTERDAM UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Elderly; Obesity; Protein needs; Treatment; Weight loss

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; APPENDICULAR MUSCLE; ARTICLE; BODY MASS; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DUAL ENERGY X RAY ABSORPTIOMETRY; EXPLORATORY RESEARCH; FAT FREE MASS; FEMALE; HUMAN; LOW CALORY DIET; MAJOR CLINICAL STUDY; MALE; MUSCLE MASS; NUTRITIONAL REQUIREMENT; OBESITY; PATIENT COMPLIANCE; POST HOC ANALYSIS; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL; REFERENCE VALUE; RESISTANCE TRAINING; SEX DIFFERENCE; SKELETAL MUSCLE; TREATMENT DURATION; WEIGHT REDUCTION; ADMINISTRATION AND DOSAGE; CALORIC INTAKE; DIET THERAPY; HAND STRENGTH; METABOLISM; MIDDLE AGED; STATISTICAL MODEL; WAIST CIRCUMFERENCE;

PROTEIN INTAKE;

ADULT; AGED; BODY MASS INDEX; DIET, REDUCING; DIETARY PROTEINS; DOUBLE-BLIND METHOD; ENERGY INTAKE; FEMALE; HAND STRENGTH; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; NUTRITIONAL REQUIREMENTS; OBESITY; RESISTANCE TRAINING; WAIST CIRCUMFERENCE; WEIGHT LOSS;

EID: 84960500254     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2015.02.016     Document Type: Article

References (34)

1. Mathus-Vliegen E.M. Obesity management task force of the European association for the study of obesity. Prevalence, pathophysiology, health consequences and treatment options of obesity in the elderly: a guideline. Obes Facts 2012, 5(3):460-483.
2. Salihu H.M., Bonnema S.M., Alio A.P. Obesity: what is an elderly population growing into?. Maturitas 2009 May 20, 63(1):7-12.
3. Zamboni M., Mazzali G., Zoico E., Harris T.B., Meigs J.B., Di Francesco V., et al. Health consequences of obesity in the elderly: a review of four unresolved questions. Int J Obes (Lond) 2005 Sep, 29(9):1011-1029.
4. Bales C.W., Buhr G. Is obesity bad for older persons? A systematic review of the pros and cons of weight reduction in later life. J Am Med Dir Assoc 2008 Jun, 9(5):302-312.
5. Visvanathan R., Chapman I. Preventing sarcopaenia in older people. Maturitas 2010 Aug, 66(4):383-388.
6. Villareal D.T., Apovian C.M., Kushner R.F., Klein S. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, the obesity society. Obes Res 2005 Nov, 13(11):1849-1863.
7. Wolfe R.R. The underappreciated role of muscle in health and disease. Am J Clin Nutr 2006 Sep, 84(3):475-482.
8. Wolfe R.R., Miller S.L., Miller K.B. Optimal protein intake in the elderly. Clin Nutr 2008 Oct, 27(5):675-684.
9. Joint WHO/FAO/UNU Expert Consultation Protein and amino acid requirements in human nutrition. World Health Organ Tech Rep Ser 2007, 935:1-265.
10. EFSA Panel on Dietetic Products Nutrition and allergies (NDA); scientific opinion on dietary reference values for protein. EFSA J 2012, 10(2):2557.
11. Rand W.M., Pellett P.L., Young V.R. Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults. Am J Clin Nutr 2003 Jan, 77(1):109-127.
12. Deutz N.E., Bauer J.M., Barazzoni R., Biolo G., Boirie Y., Bosy-Westphal A., et al. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group. Clin Nutr 2014 Dec, 33(6):929-936.
13. Bauer J., Biolo G., Cederholm T., Cesari M., Cruz-Jentoft A.J., Morley J.E., et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc 2013 Aug, 14(8):542-559.
14. Peterson MD, Sen A, Gordon PM. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sports Exerc 43(2):249-258.
15. Evans W.J. Protein nutrition, exercise and aging. J Am Coll Nutr 2004 Dec, 23(6 Suppl.). 601S-9S.
16. Tieland M., Dirks M.L., van der Zwaluw N., Verdijk L.B., van de Rest O., de Groot L.C., et al. Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc 2012 Oct, 13(8):713-719.
17. Verreijen A.M., Verlaan S., Engberink M.F., Swinkels S., de Vogel-van den Bosch J., Weijs P.J.M. A high whey protein, leucine and vitamin D enriched supplement preserves muscle mass during intentional weight loss in obese older adults: a double blind randomized controlled trial. Am J Clin Nutr 2015 Feb, 101(2):279-286.
18. Guideline diagnostics and treatment of obesity in adults and children 2008, Dutch Institute for Healthcare Improvement CBO, Utrecht.
19. Dutch food composition database (NEVO) 2011, Voedingscentrum, The Hague.
20. Conley T.B., McCabe G.P., Lim E., Yarasheski K.E., Johnson C.A., Campbell W.W. Age and sex affect protein metabolism at protein intakes that span the range of adequacy: comparison of leucine kinetics and nitrogen balance data. J Nutr Biochem 2013 Apr, 24(4):693-699.
21. Singer P., Berger M.M., Van den Berghe G., Biolo G., Calder P., Forbes A. ESPEN Guidelines on parenteral nutrition: intensive care. Clin Nutr 2009, 28:387-400.
22. Houston D.K., Nicklas B.J., Zizza C.A. Weighty concerns: the growing prevalence of obesity among older adults. J Am Diet Assoc 2009 Nov, 109(11):1886-1895.
23. Villareal D.T., Chode S., Parimi N., Sinacore D.R., Hilton T., Armamento-Villareal R., et al. Weight loss, exercise, or both and physical function in obese older adults. N Engl J Med 2011 Mar 31, 364(13):1218-1229.
24. Waters D.L., Ward A.L., Villareal D.T. Weight loss in obese adults 65years and older: a review of the controversy. Exp Gerontol 2013 Oct, 48(10):1054-1061.
25. Shea M.K., Nicklas B.J., Marsh A.P., Houston D.K., Miller G.D., Isom S., et al. The effect of pioglitazone and resistance training on body composition in older men and women undergoing hypocaloric weight loss. Obes (Silver Spring) 2011 Aug, 19(8):1636-1646.
26. Mojtahedi M.C., Thorpe M.P., Karampinos D.C., Johnson C.L., Layman D.K., Georgiadis J.G., et al. The effects of a higher protein intake during energy restriction on changes in body composition and physical function in older women. J Gerontol A Biol Sci Med Sci 2011 Nov, 66(11):1218-1225.
27. Churchward-Venne T.A., Murphy C.H., Longland T.M., Phillips S.M. Role of protein and amino acids in promoting lean mass accretion with resistance exercise and attenuating lean mass loss during energy deficit in humans. Amino Acids 2013 Aug, 45(2):231-240.
28. Burd N.A., Yang Y., Moore D.R., Tang J.E., Tarnopolsky M.A., Phillips S.M. Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. Br J Nutr 2012 Sep 28, 108(6):958-962.
29. Breen L., Phillips S.M. Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing. Nutr Metab (Lond) 2011 Oct 5, 8:68.
30. Jourdan M., Deutz N.E., Cynober L., Aussel C. Features, causes and consequences of splanchnic sequestration of amino acid in old rats. PLoS One 2011, 6(11):e27002.
31. Boirie Y., Gachon P., Beaufrere B. Splanchnic and whole-body leucine kinetics in young and elderly men. Am J Clin Nutr 1997, 65(2):489-495.
32. Volpi E., Sheffield-Moore M., Rasmussen B.B., Wolfe R.R. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA 2001, 286(10):1206-1212.
33. Dardevet D., Remond D., Peyron M.A., Papet I., Savary-Auzeloux I., Mosoni L. Muscle wasting and resistance of muscle anabolism: the "anabolic threshold concept" for adapted nutritional strategies during sarcopenia. Sci World J 2012, 2012:269531.
34. Lang C.H., Frost R.A. Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle. Mol Med 2006, 12(11-12):291-299.