In Vitro Activation of eNOS by Mangifera indica (Careless™) and Determination of an Effective Dosage in a Randomized, Double-Blind, Human Pilot Study on Microcirculation

Planta Medica

Volumn 82, Issue 4, 2015, Pages 298-304

  Gerstgrasser, Alexandra ^a   Röchter, Sigrid ^a   Dressler, Dirk ^b   Schön, Christiane ^b   Reule, Claudia ^b   Buchwald Werner, Sybille ^a  

^a Vital Solutions Swiss AG   (Switzerland)

^b BIOTESYS GMBH   (Germany)

Author keywords

Anacardiaceae; Careless ; endothelial function; eNOS; human study; HUVEC; Mangifera indica; microcirculation

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLAVONOL; GALLIC ACID; MANGIFERA INDICA EXTRACT; MANGIFERIN; PROTOCATECHUIC ACID; NOS3 PROTEIN, HUMAN; OXYGEN;

ADULT; AGED; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; EFFECTIVE DOSE (PHARMACOLOGY); ENZYME ACTIVATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPEREMIA; IN VITRO STUDY; MANGO; MICROCIRCULATION; NORMAL HUMAN; PILOT STUDY; PULSE AMPLITUDE TONOMETRY; RANDOMIZED CONTROLLED TRIAL; SIMULATION; SKIN BLOOD FLOW; SPECTROPHOTOMETER; TIME; TONOMETRY; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; BLOOD; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MANGIFERA; METABOLISM; MIDDLE AGED;

CELLS, CULTURED; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FEMALE; HUMANS; MANGIFERA; MICROCIRCULATION; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN; PILOT PROJECTS;

EID: 84960494315     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1558219     Document Type: Article

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