메뉴 건너뛰기




Volumn 26, Issue 3, 2016, Pages 171-175

Genetically predicted 17beta-estradiol and cardiovascular risk factors in women: A Mendelian randomization analysis using young women in Hong Kong and older women in the Guangzhou Biobank Cohort Study

Author keywords

Cardiovascular risk factors; Chinese; Estrogen; Mendelian randomization analysis; Women

Indexed keywords

ESTRADIOL; GENETIC MARKER;

EID: 84960439148     PISSN: 10472797     EISSN: 18732585     Source Type: Journal    
DOI: 10.1016/j.annepidem.2016.01.005     Document Type: Article
Times cited : (6)

References (36)
  • 1
    • 84924973471 scopus 로고    scopus 로고
    • Effects of low-dose versus placebo or conventional-dose postmenopausal hormone therapy on variables related to cardiovascular risk: a systematic review and meta-analyses of randomized clinical trials
    • Casanova G., Bossardi Ramos R., Ziegelmann P., Spritzer P.M. Effects of low-dose versus placebo or conventional-dose postmenopausal hormone therapy on variables related to cardiovascular risk: a systematic review and meta-analyses of randomized clinical trials. J Clin Endocrinol Metab 2015, 100(3):1028-1037.
    • (2015) J Clin Endocrinol Metab , vol.100 , Issue.3 , pp. 1028-1037
    • Casanova, G.1    Bossardi Ramos, R.2    Ziegelmann, P.3    Spritzer, P.M.4
  • 2
    • 84884917272 scopus 로고    scopus 로고
    • Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials
    • Manson J.E., Chlebowski R.T., Stefanick M.L., Aragaki A.K., Rossouw J.E., Prentice R.L., et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA 2013, 310(13):1353-1368.
    • (2013) JAMA , vol.310 , Issue.13 , pp. 1353-1368
    • Manson, J.E.1    Chlebowski, R.T.2    Stefanick, M.L.3    Aragaki, A.K.4    Rossouw, J.E.5    Prentice, R.L.6
  • 3
    • 23944460333 scopus 로고    scopus 로고
    • Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial
    • Prentice R.L., Langer R., Stefanick M.L., Howard B.V., Pettinger M., Anderson G., et al. Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial. Am J Epidemiol 2005, 162(5):404-414.
    • (2005) Am J Epidemiol , vol.162 , Issue.5 , pp. 404-414
    • Prentice, R.L.1    Langer, R.2    Stefanick, M.L.3    Howard, B.V.4    Pettinger, M.5    Anderson, G.6
  • 4
    • 84927039506 scopus 로고    scopus 로고
    • Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis
    • Hodis H.N., Mack W.J., Shoupe D., Azen S.P., Stanczyk F.Z., Hwang-Levine J., et al. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause (New York, NY) 2015, 22(4):391-401.
    • (2015) Menopause (New York, NY) , vol.22 , Issue.4 , pp. 391-401
    • Hodis, H.N.1    Mack, W.J.2    Shoupe, D.3    Azen, S.P.4    Stanczyk, F.Z.5    Hwang-Levine, J.6
  • 5
    • 34548043257 scopus 로고    scopus 로고
    • Invited commentary: hormone therapy and risk of coronary heart disease why renew the focus on the early years of menopause?
    • Manson J.E., Bassuk S.S. Invited commentary: hormone therapy and risk of coronary heart disease why renew the focus on the early years of menopause?. Am J Epidemiol 2007, 166(5):511-517.
    • (2007) Am J Epidemiol , vol.166 , Issue.5 , pp. 511-517
    • Manson, J.E.1    Bassuk, S.S.2
  • 6
    • 0037208992 scopus 로고    scopus 로고
    • Hormone replacement therapy in epidemiologic studies and randomized clinical trials - are we checkmate?
    • Michels K.B. Hormone replacement therapy in epidemiologic studies and randomized clinical trials - are we checkmate?. Epidemiology 2003, 14(1):3-5.
    • (2003) Epidemiology , vol.14 , Issue.1 , pp. 3-5
    • Michels, K.B.1
  • 7
    • 84877780704 scopus 로고    scopus 로고
    • Mendelian randomization and estimation of treatment efficacy for chronic diseases
    • Schooling C.M., Freeman G., Cowling B.J. Mendelian randomization and estimation of treatment efficacy for chronic diseases. Am J Epidemiol 2013, 177(10):1128-1133.
    • (2013) Am J Epidemiol , vol.177 , Issue.10 , pp. 1128-1133
    • Schooling, C.M.1    Freeman, G.2    Cowling, B.J.3
  • 8
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor D.A., Harbord R.M., Sterne J.A., Timpson N., Davey-Smith G. Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology. Stat Med 2008, 27(8):1133-1163.
    • (2008) Stat Med , vol.27 , Issue.8 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey-Smith, G.5
  • 9
    • 84880230242 scopus 로고    scopus 로고
    • Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
    • Wensley F., Gao P., Burgess S., Kaptoge S., Di Angelantonio E., Shah T., et al. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 2011, 342:d548.
    • (2011) BMJ , vol.342 , pp. d548
    • Wensley, F.1    Gao, P.2    Burgess, S.3    Kaptoge, S.4    Di Angelantonio, E.5    Shah, T.6
  • 10
    • 84876992300 scopus 로고    scopus 로고
    • Mendelian Randomization Estimates May Be Inflated
    • Schooling C.M., Au Yeung S.L., Freeman G. Mendelian Randomization Estimates May Be Inflated. J Am Coll Cardiol 2013, 61(18):1931.
    • (2013) J Am Coll Cardiol , vol.61 , Issue.18 , pp. 1931
    • Schooling, C.M.1    Au Yeung, S.L.2    Freeman, G.3
  • 11
    • 84884973036 scopus 로고    scopus 로고
    • Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators
    • Pierce B.L., Burgess S. Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators. Am J Epidemiol 2013, 178(7):1177-1184.
    • (2013) Am J Epidemiol , vol.178 , Issue.7 , pp. 1177-1184
    • Pierce, B.L.1    Burgess, S.2
  • 12
    • 84896866847 scopus 로고    scopus 로고
    • Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study
    • Zhao J., Jiang C., Lam T.H., Liu B., Cheng K.K., Xu L., et al. Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study. Int J Epidemiol 2014, 43(1):140-148.
    • (2014) Int J Epidemiol , vol.43 , Issue.1 , pp. 140-148
    • Zhao, J.1    Jiang, C.2    Lam, T.H.3    Liu, B.4    Cheng, K.K.5    Xu, L.6
  • 13
    • 84904185092 scopus 로고    scopus 로고
    • Genetically predicted 17beta-estradiol and systemic inflammation in women: a separate-sample Mendelian randomisation analysis in the Guangzhou Biobank Cohort Study
    • Zhao J., Jiang C.Q., Lam T.H., Liu B., Cheng K.K., Kavikondala S., et al. Genetically predicted 17beta-estradiol and systemic inflammation in women: a separate-sample Mendelian randomisation analysis in the Guangzhou Biobank Cohort Study. J Epidemiol Community Health 2014, 68(8):780-785.
    • (2014) J Epidemiol Community Health , vol.68 , Issue.8 , pp. 780-785
    • Zhao, J.1    Jiang, C.Q.2    Lam, T.H.3    Liu, B.4    Cheng, K.K.5    Kavikondala, S.6
  • 14
    • 84929180117 scopus 로고    scopus 로고
    • Genetically predicted testosterone and systemic inflammation in men: a separate-sample Mendelian randomization analysis in older Chinese men
    • Zhao J., Jiang C., Lam T.H., Liu B., Cheng K.K., Xu L., et al. Genetically predicted testosterone and systemic inflammation in men: a separate-sample Mendelian randomization analysis in older Chinese men. PLoS One 2015, 10(5):e0126442.
    • (2015) PLoS One , vol.10 , Issue.5 , pp. e0126442
    • Zhao, J.1    Jiang, C.2    Lam, T.H.3    Liu, B.4    Cheng, K.K.5    Xu, L.6
  • 16
    • 33749603021 scopus 로고    scopus 로고
    • Cohort profile: The Guangzhou Biobank Cohort Study, a Guangzhou-Hong Kong-Birmingham collaboration
    • Jiang C., Thomas G.N., Lam T.H., Schooling C.M., Zhang W., Lao X., et al. Cohort profile: The Guangzhou Biobank Cohort Study, a Guangzhou-Hong Kong-Birmingham collaboration. Int J Epidemiol 2006, 35(4):844-852.
    • (2006) Int J Epidemiol , vol.35 , Issue.4 , pp. 844-852
    • Jiang, C.1    Thomas, G.N.2    Lam, T.H.3    Schooling, C.M.4    Zhang, W.5    Lao, X.6
  • 17
    • 84861360012 scopus 로고    scopus 로고
    • Evaluation of moderate alcohol use and cognitive function among men using a Mendelian randomization design in the Guangzhou Biobank Cohort Study
    • Au Yeung S.L., Jiang C.Q., Cheng K.K., Liu B., Zhang W.S., Lam T.H., et al. Evaluation of moderate alcohol use and cognitive function among men using a Mendelian randomization design in the Guangzhou Biobank Cohort Study. Am J Epidemiol 2012, 175(10):1021-1028.
    • (2012) Am J Epidemiol , vol.175 , Issue.10 , pp. 1021-1028
    • Au Yeung, S.L.1    Jiang, C.Q.2    Cheng, K.K.3    Liu, B.4    Zhang, W.S.5    Lam, T.H.6
  • 18
    • 36849014030 scopus 로고    scopus 로고
    • Haplotypes of the estrogen receptor beta gene and breast cancer risk
    • Breast, Prostate Cancer Cohort Consortium, Cox D.G., Bretsky P., Kraft P., Pharoah P., et al. Haplotypes of the estrogen receptor beta gene and breast cancer risk. Int J Cancer 2008, 122(2):387-392.
    • (2008) Int J Cancer , vol.122 , Issue.2 , pp. 387-392
    • Cox, D.G.1    Bretsky, P.2    Kraft, P.3    Pharoah, P.4
  • 19
    • 84866238503 scopus 로고    scopus 로고
    • Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer
    • Lundin E., Wirgin I., Lukanova A., Afanasyeva Y., Krogh V., Axelsson T., et al. Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer. Cancer Epidemiol 2012, 36(5):445-452.
    • (2012) Cancer Epidemiol , vol.36 , Issue.5 , pp. 445-452
    • Lundin, E.1    Wirgin, I.2    Lukanova, A.3    Afanasyeva, Y.4    Krogh, V.5    Axelsson, T.6
  • 20
    • 70350702803 scopus 로고    scopus 로고
    • Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer
    • Udler M.S., Azzato E.M., Healey C.S., Ahmed S., Pooley K.A., Greenberg D., et al. Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer. Int J Cancer 2009, 125(11):2687-2696.
    • (2009) Int J Cancer , vol.125 , Issue.11 , pp. 2687-2696
    • Udler, M.S.1    Azzato, E.M.2    Healey, C.S.3    Ahmed, S.4    Pooley, K.A.5    Greenberg, D.6
  • 21
    • 51649097937 scopus 로고    scopus 로고
    • A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer risk
    • Talbott K.E., Gammon M.D., Kibriya M.G., Chen Y., Teitelbaum S.L., Long C.M., et al. A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer risk. Breast Cancer Res Treat 2008, 111(3):481-487.
    • (2008) Breast Cancer Res Treat , vol.111 , Issue.3 , pp. 481-487
    • Talbott, K.E.1    Gammon, M.D.2    Kibriya, M.G.3    Chen, Y.4    Teitelbaum, S.L.5    Long, C.M.6
  • 22
    • 84960445551 scopus 로고    scopus 로고
    • Available from:
    • National Centre for Biotechnology Information Database of single nucleotide polymorphisms (SNPs). Available from: . http://www.ncbi.nlm.nih.gov/snp.
  • 23
    • 2542437775 scopus 로고    scopus 로고
    • Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study
    • Liu J., Hong Y., D'Agostino R.B., Wu Z., Wang W., Sun J., et al. Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study. JAMA 2004, 291(21):2591-2599.
    • (2004) JAMA , vol.291 , Issue.21 , pp. 2591-2599
    • Liu, J.1    Hong, Y.2    D'Agostino, R.B.3    Wu, Z.4    Wang, W.5    Sun, J.6
  • 26
    • 33746862148 scopus 로고    scopus 로고
    • Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women
    • Salpeter S.R., Walsh J.M., Ormiston T.M., Greyber E., Buckley N.S., Salpeter E.E. Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab 2006, 8(5):538-554.
    • (2006) Diabetes Obes Metab , vol.8 , Issue.5 , pp. 538-554
    • Salpeter, S.R.1    Walsh, J.M.2    Ormiston, T.M.3    Greyber, E.4    Buckley, N.S.5    Salpeter, E.E.6
  • 27
    • 33244469258 scopus 로고    scopus 로고
    • The effect of conjugated equine oestrogen on diabetes incidence: the Women's Health Initiative randomised trial
    • Bonds D.E., Lasser N., Qi L., Brzyski R., Caan B., Heiss G., et al. The effect of conjugated equine oestrogen on diabetes incidence: the Women's Health Initiative randomised trial. Diabetologia 2006, 49(3):459-468.
    • (2006) Diabetologia , vol.49 , Issue.3 , pp. 459-468
    • Bonds, D.E.1    Lasser, N.2    Qi, L.3    Brzyski, R.4    Caan, B.5    Heiss, G.6
  • 28
    • 33645299302 scopus 로고    scopus 로고
    • Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease
    • Prentice R.L., Langer R.D., Stefanick M.L., Howard B.V., Pettinger M., Anderson G.L., et al. Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease. Am J Epidemiol 2006, 163(7):589-599.
    • (2006) Am J Epidemiol , vol.163 , Issue.7 , pp. 589-599
    • Prentice, R.L.1    Langer, R.D.2    Stefanick, M.L.3    Howard, B.V.4    Pettinger, M.5    Anderson, G.L.6
  • 29
    • 84889645312 scopus 로고    scopus 로고
    • The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis
    • Zimmerman Y., Eijkemans M.J., Coelingh Bennink H.J., Blankenstein M.A., Fauser B.C. The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis. Hum Reprod Update 2014, 20(1):76-105.
    • (2014) Hum Reprod Update , vol.20 , Issue.1 , pp. 76-105
    • Zimmerman, Y.1    Eijkemans, M.J.2    Coelingh Bennink, H.J.3    Blankenstein, M.A.4    Fauser, B.C.5
  • 31
    • 84884793216 scopus 로고    scopus 로고
    • Power and sample size calculations for Mendelian randomization studies using one genetic instrument
    • Freeman G., Cowling B.J., Schooling C.M. Power and sample size calculations for Mendelian randomization studies using one genetic instrument. Int J Epidemiol 2013, 42(4):1157-1163.
    • (2013) Int J Epidemiol , vol.42 , Issue.4 , pp. 1157-1163
    • Freeman, G.1    Cowling, B.J.2    Schooling, C.M.3
  • 32
    • 0032499462 scopus 로고    scopus 로고
    • Myth and paradox of coronary risk and the menopause
    • Tunstall-Pedoe H. Myth and paradox of coronary risk and the menopause. Lancet 1998, 351(9113):1425-1427.
    • (1998) Lancet , vol.351 , Issue.9113 , pp. 1425-1427
    • Tunstall-Pedoe, H.1
  • 33
    • 3242888502 scopus 로고    scopus 로고
    • Commentary: hormone replacement therapy and coronary heart disease: four lessons
    • Petitti D. Commentary: hormone replacement therapy and coronary heart disease: four lessons. Int J Epidemiol 2004, 33(3):461-463.
    • (2004) Int J Epidemiol , vol.33 , Issue.3 , pp. 461-463
    • Petitti, D.1
  • 34
    • 9644254419 scopus 로고    scopus 로고
    • Socioeconomic position and hormone replacement therapy use: Explaining the discrepancy in evidence from observational and randomized controlled trials
    • Lawlor D.A., Davey-Smith G., Ebrahim S. Socioeconomic position and hormone replacement therapy use: Explaining the discrepancy in evidence from observational and randomized controlled trials. Am J Public Health 2004, 94(12):2149-2154.
    • (2004) Am J Public Health , vol.94 , Issue.12 , pp. 2149-2154
    • Lawlor, D.A.1    Davey-Smith, G.2    Ebrahim, S.3
  • 35
    • 23944487497 scopus 로고    scopus 로고
    • Invited commentary: how far can epidemiologists get with statistical adjustment?
    • discussion 9-20
    • Petitti D.B., Freedman D.A. Invited commentary: how far can epidemiologists get with statistical adjustment?. Am J Epidemiol 2005, 162(5):415-418. discussion 9-20.
    • (2005) Am J Epidemiol , vol.162 , Issue.5 , pp. 415-418
    • Petitti, D.B.1    Freedman, D.A.2
  • 36
    • 58149476776 scopus 로고    scopus 로고
    • Contraceptive hormone use and cardiovascular disease
    • Shufelt C.L., Bairey Merz C.N. Contraceptive hormone use and cardiovascular disease. J Am Coll Cardiol 2009, 53(3):221-231.
    • (2009) J Am Coll Cardiol , vol.53 , Issue.3 , pp. 221-231
    • Shufelt, C.L.1    Bairey Merz, C.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.