-
1
-
-
84865846727
-
Genomic analysis of high-risk smoldering multiple myeloma
-
López-Corral L, Mateos MV, Corchete LA, et al. Genomic analysis of high-risk smoldering multiple myeloma. Haematologica. 2012;97(9):1439-1443.
-
(2012)
Haematologica
, vol.97
, Issue.9
, pp. 1439-1443
-
-
López-Corral, L.1
Mateos, M.V.2
Corchete, L.A.3
-
2
-
-
79953322412
-
The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells
-
López-Corral L, Gutiérrez NC, Vidriales MB, et al. The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells. Clin Cancer Res. 2011;17(7):1692-1700.
-
(2011)
Clin Cancer Res.
, vol.17
, Issue.7
, pp. 1692-1700
-
-
López-Corral, L.1
Gutiérrez, N.C.2
Vidriales, M.B.3
-
3
-
-
84893810104
-
Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms
-
Walker BA, Wardell CP, Melchor L, et al. Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms. Leukemia. 2014;28(2):384-390.
-
(2014)
Leukemia
, vol.28
, Issue.2
, pp. 384-390
-
-
Walker, B.A.1
Wardell, C.P.2
Melchor, L.3
-
4
-
-
84871233578
-
SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status
-
López-Corral L, Sarasquete ME, Beà S, et al. SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status. Leukemia. 2012;26(12):2521-2529.
-
(2012)
Leukemia
, vol.26
, Issue.12
, pp. 2521-2529
-
-
López-Corral, L.1
Sarasquete, M.E.2
Beà, S.3
-
5
-
-
84892871404
-
Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del (17p), t (4;14), gain 1q, hyperdiploidy, and tumor load
-
Neben K, Jauch A, Hielscher T, et al. Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del (17p), t (4;14), gain 1q, hyperdiploidy, and tumor load. J Clin Oncol. 2013;31(34):4325-4332.
-
(2013)
J Clin Oncol.
, vol.31
, Issue.34
, pp. 4325-4332
-
-
Neben, K.1
Jauch, A.2
Hielscher, T.3
-
6
-
-
84881477133
-
Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma
-
Rajkumar SV, Gupta V, Fonseca R, et al. Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma. Leukemia. 2013;27(8):1738-1744.
-
(2013)
Leukemia
, vol.27
, Issue.8
, pp. 1738-1744
-
-
Rajkumar, S.V.1
Gupta, V.2
Fonseca, R.3
-
7
-
-
84904060605
-
Serial exome analysis of disease progression in premalignant gammopathies
-
Zhao S, Choi M, Heuck C, et al. Serial exome analysis of disease progression in premalignant gammopathies. Leukemia. 2014;28(7):1548-1552.
-
(2014)
Leukemia
, vol.28
, Issue.7
, pp. 1548-1552
-
-
Zhao, S.1
Choi, M.2
Heuck, C.3
-
9
-
-
34547677725
-
Immunodeficiency and immunotherapy in multiple myeloma
-
Pratt G, Goodyear O, Moss P. Immunodeficiency and immunotherapy in multiple myeloma. Br J Haematol. 2007;138(5):563-579.
-
(2007)
Br J Haematol.
, vol.138
, Issue.5
, pp. 563-579
-
-
Pratt, G.1
Goodyear, O.2
Moss, P.3
-
10
-
-
84961551887
-
The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies
-
Dosani T, Carlsten M, Maric I, Landgren O. The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies. Blood Cancer J. 2015;5:e306.
-
(2015)
Blood Cancer J
, vol.5
, pp. e306
-
-
Dosani, T.1
Carlsten, M.2
Maric, I.3
Landgren, O.4
-
11
-
-
34948907366
-
New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells
-
Pérez-Persona E, Vidriales MB, Mateo G, et al. New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells. Blood. 2007;110(7):2586-2592.
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2586-2592
-
-
Pérez-Persona, E.1
Vidriales, M.B.2
Mateo, G.3
-
12
-
-
27644457376
-
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
-
Thomas DA, Massagué J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell. 2005;8(5):369-380.
-
(2005)
Cancer Cell.
, vol.8
, Issue.5
, pp. 369-380
-
-
Thomas, D.A.1
Massagué, J.2
-
13
-
-
0035525736
-
Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8 (1) CD57 (1) CD28 (-) compartment
-
Sze DM, Giesajtis G, Brown RD, et al. Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8 (1) CD57 (1) CD28 (-) compartment. Blood. 2001;98(9):2817-2827.
-
(2001)
Blood
, vol.98
, Issue.9
, pp. 2817-2827
-
-
Sze, D.M.1
Giesajtis, G.2
Brown, R.D.3
-
14
-
-
0032427590
-
The expression of T cell related costimulatory molecules in multiple myeloma
-
Brown RD, Pope B, Yuen E, Gibson J, Joshua DE. The expression of T cell related costimulatory molecules in multiple myeloma. Leuk Lymphoma. 1998;31(3-4):379-384.
-
(1998)
Leuk Lymphoma.
, vol.31
, Issue.3-4
, pp. 379-384
-
-
Brown, R.D.1
Pope, B.2
Yuen, E.3
Gibson, J.4
Joshua, D.E.5
-
15
-
-
77957701558
-
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody
-
Benson DM Jr, Bakan CE, Mishra A, et al. The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood. 2010;116(13):2286-2294.
-
(2010)
Blood
, vol.116
, Issue.13
, pp. 2286-2294
-
-
Benson, D.M.1
Bakan, C.E.2
Mishra, A.3
-
16
-
-
84943587397
-
PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma
-
Paiva B, Azpilikueta A, Puig N, et al. PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma. Leukemia. 2015;29(10):2110-2113.
-
(2015)
Leukemia
, vol.29
, Issue.10
, pp. 2110-2113
-
-
Paiva, B.1
Azpilikueta, A.2
Puig, N.3
-
17
-
-
84895784261
-
New drugs and novel mechanisms of action in multiple myeloma in 2013: A report from the International Myeloma Working Group (IMWG)
-
Ocio EM, Richardson PG, Rajkumar SV, et al. New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG). Leukemia. 2014;28(3):525-542.
-
(2014)
Leukemia
, vol.28
, Issue.3
, pp. 525-542
-
-
Ocio, E.M.1
Richardson, P.G.2
Rajkumar, S.V.3
-
18
-
-
34250694807
-
Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma
-
Kyle RA, Remstein ED, Therneau TM, et al. Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma. N Engl J Med. 2007;356(25):2582-2590.
-
(2007)
N Engl J Med.
, vol.356
, Issue.25
, pp. 2582-2590
-
-
Kyle, R.A.1
Remstein, E.D.2
Therneau, T.M.3
-
19
-
-
84880862419
-
Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma
-
Mateos MV, Hernández MT, Giraldo P, et al. Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma. N Engl J Med. 2013;369(5):438-447.
-
(2013)
N Engl J Med.
, vol.369
, Issue.5
, pp. 438-447
-
-
Mateos, M.V.1
Hernández, M.T.2
Giraldo, P.3
-
20
-
-
84929088921
-
Long term follow-up on the tretament [sic] of high risk smoldering myeloma with lenalidomide plus low dose dex (rd) (phase III Spanish trial): Persistent benefit in overall survival [abstract]
-
3465
-
Mateos M, Hernandez MT, Giraldo P, et al. Long term follow-up on the tretament [sic] of high risk smoldering myeloma with lenalidomide plus low dose dex (rd) (phase III spanish trial): persistent benefit in overall survival [abstract]. Blood. 2014;124(21). Abstract 3465.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
Mateos, M.1
Hernandez, M.T.2
Giraldo, P.3
-
21
-
-
84886945614
-
Are the immuno-stimulatory properties of lenalidomide extinguished by co-administration of Dexamethasone?
-
Hsu A, Ritchie DS, Neeson P. Are the immuno-stimulatory properties of lenalidomide extinguished by co-administration of Dexamethasone? OncoImmunology. 2012;1(3):372-374.
-
(2012)
OncoImmunology
, vol.1
, Issue.3
, pp. 372-374
-
-
Hsu, A.1
Ritchie, D.S.2
Neeson, P.3
-
22
-
-
79551615800
-
The immunostimulatory effect of lenalidomide on NKcell function is profoundly inhibited by concurrent dexamethasone therapy
-
Hsu AK, Quach H, Tai T, et al. The immunostimulatory effect of lenalidomide on NKcell function is profoundly inhibited by concurrent dexamethasone therapy. Blood. 2011;117(5):1605-1613.
-
(2011)
Blood
, vol.117
, Issue.5
, pp. 1605-1613
-
-
Hsu, A.K.1
Quach, H.2
Tai, T.3
-
23
-
-
83455225450
-
Effect of combined dexamethasone/lenalidomide therapy on NK cell-receptor levels in myeloma patients
-
author reply 6466-6468
-
Carter CR, Feyler S, Smalle N, et al. Effect of combined dexamethasone/lenalidomide therapy on NK cell-receptor levels in myeloma patients. Blood. 2011;118(24):6465-6466, author reply 6466-6468.
-
(2011)
Blood
, vol.118
, Issue.24
, pp. 6465-6466
-
-
Carter, C.R.1
Feyler, S.2
Smalle, N.3
-
24
-
-
84903957798
-
Treatment with lenalidomide induces immunoactivating and counter-regulatory immunosuppressive changes in myeloma patients
-
Busch A, Zeh D, Janzen V, et al. Treatment with lenalidomide induces immunoactivating and counter-regulatory immunosuppressive changes in myeloma patients. Clin Exp Immunol. 2014;177(2):439-453.
-
(2014)
Clin Exp Immunol.
, vol.177
, Issue.2
, pp. 439-453
-
-
Busch, A.1
Zeh, D.2
Janzen, V.3
-
25
-
-
77950644007
-
Dexamethasone synergizes with lenalidomide to inhibit multiple myeloma tumor growth, but reduces lenalidomide-induced immunomodulation of T and NK cell function
-
Gandhi AK, Kang J, Capone L, et al. Dexamethasone synergizes with lenalidomide to inhibit multiple myeloma tumor growth, but reduces lenalidomide-induced immunomodulation of T and NK cell function. Curr Cancer Drug Targets. 2010;10(2):155-167.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, Issue.2
, pp. 155-167
-
-
Gandhi, A.K.1
Kang, J.2
Capone, L.3
-
26
-
-
84885020018
-
Haematological cancer: Treatment of smoldering multiple myeloma
-
Rajkumar SV, Kyle RA. Haematological cancer: Treatment of smoldering multiple myeloma. Nat Rev Clin Oncol. 2013;10(10):554-555.
-
(2013)
Nat Rev Clin Oncol.
, vol.10
, Issue.10
, pp. 554-555
-
-
Rajkumar, S.V.1
Kyle, R.A.2
-
27
-
-
84865855905
-
EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols
-
Kalina T, Flores-Montero J, van der Velden VH, et al; EuroFlow Consortium (EU-FP6, LSHB-CT-2006-018708). EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols. Leukemia. 2012;26(9):1986-2010.
-
(2012)
Leukemia
, vol.26
, Issue.9
, pp. 1986-2010
-
-
EuroFlow Consortium (EU-FP6, LSHB-CT-2006-018708),1
Kalina, T.2
Flores-Montero, J.3
Van Der Velden, V.H.4
-
28
-
-
84892495770
-
Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile
-
Paiva B, Paino T, Sayagues JM, et al. Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile. Blood. 2013;122(22):3591-3598.
-
(2013)
Blood
, vol.122
, Issue.22
, pp. 3591-3598
-
-
Paiva, B.1
Paino, T.2
Sayagues, J.M.3
-
29
-
-
84908604358
-
International myeloma working group updated criteria for the diagnosis of multiple myeloma
-
Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15(12):e538-e548.
-
(2014)
Lancet Oncol.
, vol.15
, Issue.12
, pp. e538-e548
-
-
Rajkumar, S.V.1
Dimopoulos, M.A.2
Palumbo, A.3
-
30
-
-
84891819060
-
Clinical, genomic, and imaging predictors of myeloma progression from asymptomatic monoclonal gammopathies (SWOG S0120)
-
Dhodapkar MV, Sexton R, Waheed S, et al. Clinical, genomic, and imaging predictors of myeloma progression from asymptomatic monoclonal gammopathies (SWOG S0120). Blood. 2014;123(1):78-85.
-
(2014)
Blood
, vol.123
, Issue.1
, pp. 78-85
-
-
Dhodapkar, M.V.1
Sexton, R.2
Waheed, S.3
-
31
-
-
84879072352
-
Differential expression of natural killer cell activating receptors in blood versus bone marrow in patients with monoclonal gammopathy
-
Costello RT, Boehrer A, Sanchez C, et al. Differential expression of natural killer cell activating receptors in blood versus bone marrow in patients with monoclonal gammopathy. Immunology. 2013;139(3):338-341.
-
(2013)
Immunology
, vol.139
, Issue.3
, pp. 338-341
-
-
Costello, R.T.1
Boehrer, A.2
Sanchez, C.3
-
32
-
-
53449089919
-
Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma
-
Dhodapkar KM, Barbuto S, Matthews P, et al. Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma. Blood. 2008;112(7):2878-2885.
-
(2008)
Blood
, vol.112
, Issue.7
, pp. 2878-2885
-
-
Dhodapkar, K.M.1
Barbuto, S.2
Matthews, P.3
-
33
-
-
0038543513
-
A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
-
Dhodapkar MV, Geller MD, Chang DH, et al. A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma. J Exp Med. 2003;197(12):1667-1676.
-
(2003)
J Exp Med.
, vol.197
, Issue.12
, pp. 1667-1676
-
-
Dhodapkar, M.V.1
Geller, M.D.2
Chang, D.H.3
-
34
-
-
0345599884
-
Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy
-
Dhodapkar MV, Krasovsky J, Osman K, Geller MD. Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy. J Exp Med. 2003;198(11):1753-1757.
-
(2003)
J Exp Med.
, vol.198
, Issue.11
, pp. 1753-1757
-
-
Dhodapkar, M.V.1
Krasovsky, J.2
Osman, K.3
Geller, M.D.4
-
35
-
-
33646477295
-
Impaired activating receptor expression pattern in natural killer cells from patients with multiple myeloma
-
Fauriat C, Mallet F, Olive D, Costello RT. Impaired activating receptor expression pattern in natural killer cells from patients with multiple myeloma. Leukemia. 2006;20(4):732-733.
-
(2006)
Leukemia
, vol.20
, Issue.4
, pp. 732-733
-
-
Fauriat, C.1
Mallet, F.2
Olive, D.3
Costello, R.T.4
-
36
-
-
39549084084
-
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
-
Jinushi M, Vanneman M, Munshi NC, et al. MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci USA. 2008;105(4):1285-1290.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.4
, pp. 1285-1290
-
-
Jinushi, M.1
Vanneman, M.2
Munshi, N.C.3
-
37
-
-
38849089445
-
Peripheral blood dendritic cell subsets from patients with monoclonal gammopathies show an abnormal distribution and are functionally impaired
-
Martín-Ayuso M, Almeida J, Pérez-Andrés M, et al. Peripheral blood dendritic cell subsets from patients with monoclonal gammopathies show an abnormal distribution and are functionally impaired. Oncologist. 2008;13(1):82-92.
-
(2008)
Oncologist
, vol.13
, Issue.1
, pp. 82-92
-
-
Martín-Ayuso, M.1
Almeida, J.2
Pérez-Andrés, M.3
-
38
-
-
78149322663
-
A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma
-
Noonan K, Marchionni L, Anderson J, Pardoll D, Roodman GD, Borrello I. A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma. Blood. 2010;116(18):3554-3563.
-
(2010)
Blood
, vol.116
, Issue.18
, pp. 3554-3563
-
-
Noonan, K.1
Marchionni, L.2
Anderson, J.3
Pardoll, D.4
Roodman, G.D.5
Borrello, I.6
-
39
-
-
10644224388
-
High Th1/Th2 ratio in patients with multiple myeloma
-
Ogawara H, Handa H, Yamazaki T, et al. High Th1/Th2 ratio in patients with multiple myeloma. Leuk Res. 2005;29(2):135-140.
-
(2005)
Leuk Res.
, vol.29
, Issue.2
, pp. 135-140
-
-
Ogawara, H.1
Handa, H.2
Yamazaki, T.3
-
40
-
-
33644847914
-
Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates increased infiltration by cytotoxic/Th1 T cells demonstrating a squed TCRVbeta repertoire
-
Pérez-Andres M, Almeida J, Martin-Ayuso M, et al; Spanish Network on Multiple Myeloma; Spanish Network of Cancer Research Centers. Characterization of bone marrow T cells in monoclonal gammopathy of undetermined significance, multiple myeloma, and plasma cell leukemia demonstrates increased infiltration by cytotoxic/Th1 T cells demonstrating a squed TCRVbeta repertoire. Cancer. 2006;106(6):1296-1305.
-
(2006)
Cancer
, vol.106
, Issue.6
, pp. 1296-1305
-
-
Spanish Network on Multiple Myeloma1
Spanish Network of Cancer Research Centers2
Pérez-Andres, M.3
Almeida, J.4
Martin-Ayuso, M.5
-
41
-
-
84872087150
-
Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry
-
Pessoa de Magalhães RJ, Vidriales MB, Paiva B, et al; Spanish Myeloma Group (GEM); Grupo Castellano-Leones de Gammapatias Monoclonales, cooperative study groups. Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry. Haematologica. 2013;98(1):79-86.
-
(2013)
Haematologica
, vol.98
, Issue.1
, pp. 79-86
-
-
Pessoa De Magalhães, R.J.1
Vidriales, M.B.2
Paiva, B.3
-
42
-
-
77955862810
-
Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
-
Prabhala RH, Pelluru D, Fulciniti M, et al. Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma. Blood. 2010;115(26):5385-5392.
-
(2010)
Blood
, vol.115
, Issue.26
, pp. 5385-5392
-
-
Prabhala, R.H.1
Pelluru, D.2
Fulciniti, M.3
-
43
-
-
84885350915
-
Long-term survival in multiple myeloma is associated with a distinct immunological profile, which includes proliferative cytotoxic T-cell clones and a favourable Treg/Th17 balance
-
Bryant C, Suen H, Brown R, et al. Long-term survival in multiple myeloma is associated with a distinct immunological profile, which includes proliferative cytotoxic T-cell clones and a favourable Treg/Th17 balance. Blood Cancer J. 2013;3:e148.
-
(2013)
Blood Cancer J
, vol.3
, pp. e148
-
-
Bryant, C.1
Suen, H.2
Brown, R.3
-
44
-
-
38349136782
-
Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma
-
Dispenzieri A, Kyle RA, Katzmann JA, et al. Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma. Blood. 2008;111(2):785-789.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 785-789
-
-
Dispenzieri, A.1
Kyle, R.A.2
Katzmann, J.A.3
-
45
-
-
84856423569
-
The frequency of T regulatory cells modulates the survival of multiple myeloma patients: Detailed characterisation of immune status in multiple myeloma
-
Giannopoulos K, Kaminska W, Hus I, Dmoszynska A. The frequency of T regulatory cells modulates the survival of multiple myeloma patients: detailed characterisation of immune status in multiple myeloma. Br J Cancer. 2012;106(3):546-552.
-
(2012)
Br J Cancer
, vol.106
, Issue.3
, pp. 546-552
-
-
Giannopoulos, K.1
Kaminska, W.2
Hus, I.3
Dmoszynska, A.4
-
46
-
-
84867372743
-
Increased T regulatory cells are associated with adverse clinical features and predict progression in multiple myeloma
-
Muthu Raja KR, Rihova L, Zahradova L, Klincova M, Penka M, Hajek R. Increased T regulatory cells are associated with adverse clinical features and predict progression in multiple myeloma. PLoS One. 2012;7(10):e47077.
-
(2012)
PLoS One
, vol.7
, Issue.10
, pp. e47077
-
-
Muthu Raja, K.R.1
Rihova, L.2
Zahradova, L.3
Klincova, M.4
Penka, M.5
Hajek, R.6
-
47
-
-
84892576029
-
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
-
Krönke J, Udeshi ND, Narla A, et al. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science. 2014;343(6168):301-305.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 301-305
-
-
Krönke, J.1
Udeshi, N.D.2
Narla, A.3
-
48
-
-
84892593087
-
The myeloma drug lenalidomide promotes the cereblondependent destruction of Ikaros proteins
-
Lu G, Middleton RE, Sun H, et al. The myeloma drug lenalidomide promotes the cereblondependent destruction of Ikaros proteins. Science. 2014;343(6168):305-309.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 305-309
-
-
Lu, G.1
Middleton, R.E.2
Sun, H.3
-
49
-
-
84937827650
-
Lenalidomide augments actin remodeling and lowers NK-cell activation thresholds
-
Lagrue K, Carisey A, Morgan DJ, Chopra R, Davis DM. Lenalidomide augments actin remodeling and lowers NK-cell activation thresholds. Blood. 2015;126(1):50-60.
-
(2015)
Blood
, vol.126
, Issue.1
, pp. 50-60
-
-
Lagrue, K.1
Carisey, A.2
Morgan, D.J.3
Chopra, R.4
Davis, D.M.5
-
50
-
-
33745961875
-
Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: Therapeutic implications
-
Chang DH, Liu N, Klimek V, et al. Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implications. Blood. 2006;108(2):618-621.
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 618-621
-
-
Chang, D.H.1
Liu, N.2
Klimek, V.3
-
51
-
-
84933567284
-
Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: Impact of immune activation and cereblon targets
-
Sehgal K, Das R, Zhang L, et al. Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets. Blood. 2015;125(26):4042-4051.
-
(2015)
Blood
, vol.125
, Issue.26
, pp. 4042-4051
-
-
Sehgal, K.1
Das, R.2
Zhang, L.3
-
52
-
-
84862742268
-
Induction by lenalidomide and dexamethasone combination increases regulatory cells of patients with previously untreated multiple myeloma
-
Muthu Raja KR, Kovarova L, Hajek R. Induction by lenalidomide and dexamethasone combination increases regulatory cells of patients with previously untreated multiple myeloma. Leuk Lymphoma. 2012;53(7):1406-1408.
-
(2012)
Leuk Lymphoma
, vol.53
, Issue.7
, pp. 1406-1408
-
-
Muthu Raja, K.R.1
Kovarova, L.2
Hajek, R.3
-
53
-
-
84940449779
-
Downregulation of myeloma-induced ICOS-L and regulatory T cell generation by lenalidomide and dexamethasone therapy
-
Scott GB, Carter C, Parrish C, Wood PM, Cook G. Downregulation of myeloma-induced ICOS-L and regulatory T cell generation by lenalidomide and dexamethasone therapy. Cell Immunol. 2015;297(1):1-9.
-
(2015)
Cell Immunol.
, vol.297
, Issue.1
, pp. 1-9
-
-
Scott, G.B.1
Carter, C.2
Parrish, C.3
Wood, P.M.4
Cook, G.5
-
54
-
-
77951640552
-
TNF activates a NF-kappaB-regulated cellular program in human CD45RA-regulatory T cells that modulates their suppressive function
-
Nagar M, Jacob-Hirsch J, Vernitsky H, et al. TNF activates a NF-kappaB-regulated cellular program in human CD45RA-regulatory T cells that modulates their suppressive function. J Immunol. 2010;184(7):3570-3581.
-
(2010)
J Immunol.
, vol.184
, Issue.7
, pp. 3570-3581
-
-
Nagar, M.1
Jacob-Hirsch, J.2
Vernitsky, H.3
-
55
-
-
84942326495
-
Engineering antimyeloma responses using affinity-enhanced TCRengineered T cells
-
San Miguel JF, Paiva B, Lasarte JJ. Engineering antimyeloma responses using affinity-enhanced TCRengineered T cells. Cancer Cell. 2015;28(3):281-283.
-
(2015)
Cancer Cell.
, vol.28
, Issue.3
, pp. 281-283
-
-
San Miguel, J.F.1
Paiva, B.2
Lasarte, J.J.3
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