MiRNA targeting of oxysterol-binding protein-like 6 regulates cholesterol trafficking and efflux

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 5, 2016, Pages 942-951

  Ouimet, Mireille ^a   Hennessy, Elizabeth J ^a   Van Solingen, Coen ^a   Koelwyn, Graeme J ^a   Hussein, Maryem A ^a   Ramkhelawon, Bhama ^a   Rayner, Katey J ^a,b   Temel, Ryan E ^c   Perisic, Ljubica ^d   Hedin, Ulf ^d   Maegdefessel, Lars ^d   Garabedian, Michael J ^a   Holdt, Lesca M ^e   Teupser, Daniel ^e   Moore, Kathryn J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^c UNIVERSITY OF KENTUCKY   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

cholesterol; cholesterol homeostasis; lipids and lipoproteins; macrophages; microRNA

Indexed keywords

BINDING PROTEIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER X RECEPTOR; MICRORNA; MIR 27B; MIR 33; OXYSTEROL; OXYSTEROL BINDING PROTEIN LIKE 6; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ABC TRANSPORTER A1; ABCA1 PROTEIN, HUMAN; LOW DENSITY LIPOPROTEIN RECEPTOR; MIRN27 MICRORNA, HUMAN; MIRN27 MICRORNA, MOUSE; MIRN33 MICRORNA, HUMAN; MIRN33 MICRORNA, MOUSE; OXYSTEROL BINDING PROTEIN; PROTEIN BINDING; STEROID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELLULAR DISTRIBUTION; CHOLESTEROL ESTERIFICATION; CHOLESTEROL HOMEOSTASIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOSTASIS; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; WESTERN DIET; 3' UNTRANSLATED REGION; ANIMAL; ATHEROSCLEROSIS; BINDING SITE; BLOOD; C57BL MOUSE; CHLOROCEBUS AETHIOPS; DEFICIENCY; DISEASE MODEL; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HEP-G2 CELL LINE; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TRANSPORT AT THE CELLULAR LEVEL;

3' UNTRANSLATED REGIONS; ANIMALS; ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; BINDING SITES; BIOLOGICAL TRANSPORT; CERCOPITHECUS AETHIOPS; CHOLESTEROL; CHOLESTEROL, HDL; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; HEK293 CELLS; HEP G2 CELLS; HEPATOCYTES; HUMANS; LIVER X RECEPTORS; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; PLAQUE, ATHEROSCLEROTIC; PROTEIN BINDING; RECEPTORS, LDL; RECEPTORS, STEROID; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84960157214     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307282     Document Type: Article

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