Membrane-bound PenA β-lactamase of Burkholderia pseudomallei

Antimicrobial Agents and Chemotherapy

Volumn 60, Issue 3, 2016, Pages 1509-1514

  Randall, Linnell B ^a,b   Dobos, Karen ^b   Papp Wallace, Krisztina M ^c   Bonomo, Robert A ^c,d   Schweizer, Herbert P ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMPICILLIN; BETA LACTAMASE; CARBENICILLIN; CEFTAZIDIME; CYSTEINE; GLOBOMYCIN; IMIPENEM; ISOLEUCINE; LIPOPROTEIN; MEMBRANE BOUND PENA BETA LACTAMASE; SERINE; SIGNAL PEPTIDASE I; SIGNAL PEPTIDE; TRITON X 114; UNCLASSIFIED DRUG; MACROGOL DERIVATIVE; NONIDET P-40; PEPTIDE;

ARTICLE; BURKHOLDERIA PSEUDOMALLEI; ENZYME ACTIVITY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING; ANTIBIOTIC RESISTANCE; CELL MEMBRANE; CHEMISTRY; DRUG EFFECTS; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; METABOLISM; MICROBIAL SENSITIVITY TEST; MUTATION; PHYSIOLOGY;

BETA-LACTAMASES; BURKHOLDERIA PSEUDOMALLEI; CELL MEMBRANE; DRUG RESISTANCE, BACTERIAL; LIPOPROTEINS; MICROBIAL SENSITIVITY TESTS; MUTATION; PEPTIDES; POLYETHYLENE GLYCOLS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBSTRATE SPECIFICITY;

EID: 84960157192     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02444-15     Document Type: Article

References (39)

1. Wiersinga WJ, Currie BJ, Peacock SJ. 2012. Melioidosis. N Engl J Med 367:1035-1044. http://dx.doi.org/10.1056/NEJMra1204699.
2. Wuthiekanun V, Peacock SJ. 2006. Management of melioidosis. Expert Rev Anti Infect Ther 4:445-455. http://dx.doi.org/10.1586/14787210.4.3.445.
3. Schweizer HP. 2012. Mechanisms of antibiotic resistance in Burkholderia pseudomallei: implications for treatment of melioidosis. Future Microbiol 7:1389-1399. http://dx.doi.org/10.2217/fmb.12.116.
4. Dance D. 2014. Treatment and prophylaxis of melioidosis. Int J Antimicrob Agents 43:310-318. http://dx.doi.org/10.1016/j.ijantimicag.2014.01.005.
5. White NJ, Dance DA, Chaowagul W, Wattanagoon Y, Wuthiekanun V, Pitakwatchara N. 1989. Halving of mortality of severe melioidosis by ceftazidime. Lancet ii: 697-701.
6. Lipsitz R, Garges S, Aurigemma R, Baccam P, Blaney DD, Cheng AC, Currie BJ, Dance D, Gee JE, Larsen J, Limmathurotsakul D, Morrow MG, Norton R, O'Mara E, Peacock SJ, Pesik N, Rogers LP, Schweizer HP, Steinmetz I, Tan G, Tan P, Wiersinga WJ, Wuthiekanun V, Smith TL. 2012. Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010. Emerg Infect Dis 18:e2. http://dx.doi.org/10.3201/eid1812.120638.
7. Wuthiekanun V, Amornchai P, Saiprom N, Chantratita N, Chierakul W, Koh GC, Chaowagul W, Day NP, Limmathurotsakul D, Peacock SJ. 2011. Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand. Antimicrob Agents Chemother 55:5388-5391. http://dx.doi.org/10.1128/AAC.05517-11.
8. Tribuddharat C, Moore RA, Baker P, Woods DE. 2003. Burkholderia pseudomallei class A beta-lactamase mutations that confer selective resistance against ceftazidime or clavulanic acid inhibition. Antimicrob Agents Chemother 47:2082-2087. http://dx.doi.org/10.1128/AAC.47.7.2082-2087.2003.
9. Sam IC, See KH, Puthucheary SD. 2009. Variations in ceftazidime and amoxicillin-clavulanate susceptibilities within a clonal infection of Burkholderia pseudomallei. J Clin Microbiol 47:1556-1558. http://dx.doi.org/10.1128/JCM.01657-08.
10. Rholl DA, Papp-Wallace KM, Tomaras AP, Vasil ML, Bonomo RA, Schweizer HP. 2011. Molecular investigations of PenA-mediated betalactam resistance in Burkholderia pseudomallei. Front Microbiol 2:139. http://dx.doi.org/10.3389/fmicb.2011.00139.
11. Sarovich DS, Price EP, Von Schulze AT, Cook JM, Mayo M, Watson LM, Richardson L, Seymour ML, Tuanyok A, Engelthaler DM, Pearson T, Peacock SJ, Currie BJ, Keim P, Wagner DM. 2012. Characterization of ceftazidime resistance mechanisms in clinical isolates of Burkholderia pseudomallei from Australia. PLoS One 7:e30789. http://dx.doi.org/10.1371/journal.pone.0030789.
12. Sarovich DS, Price EP, Limmathurotsakul D, Cook JM, Von Schulze AT, Wolken SR, Keim P, Peacock SJ, Pearson T. 2012. Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection. Infect Drug Resist 5:129-132. http://dx.doi.org/10.2147/IDR. S35529.
13. Chantratita N, Rholl DA, Sim B, Wuthiekanun V, Limmathurotsakul D, Amornchai P, Thanwisai A, Chua HH, Ooi WF, Holden MTG, Day NP, Tan P, Schweizer HP, Peacock SJ. 2011. Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei. Proc Natl Acad Sci U S A 108:17165-17170. http://dx.doi.org/10.1073/pnas.1111020108.
14. Papp-Wallace KM, Taracila MA, Gatta JA, Ohuchi N, Bonomo RA, Nukaga M. 2013. Insights into beta-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants. J Biol Chem 288:19090-19102. http://dx.doi.org/10.1074/jbc. M113.458315.
15. Livermore DM, Chau PY, Wong AI, Leung YK. 1987. Beta-lactamase of Pseudomonas pseudomallei and its contribution to antibiotic resistance. J Antimicrob Chemother 20:313-321. http://dx.doi.org/10.1093/jac/20.3.313.
16. Propst KL, Mima T, Choi KH, Dow SW, Schweizer HP. 2010. A Burkholderia pseudomallei ΔpurM mutant is avirulent in immunocompetent and immunodeficient animals: candidate strain for exclusion from select-agent lists. Infect Immun 78:3136-3143. http://dx.doi.org/10.1128/IAI.01313-09.
17. Lopez CM, Rholl DA, Trunck LA, Schweizer HP. 2009. Versatile dualtechnology system for markerless allele replacement in Burkholderia pseudomallei. Appl Environ Microbiol 75:6496-6503. http://dx.doi.org/10.1128/AEM.01669-09.
18. Clinical and Laboratory Standards Institute. 2015. Performance standards for antimicrobial susceptibility testing: twenty-fifth informal supplement M100-S25. Clinical and Laboratory Standards Institute, Wayne, PA.
19. Choi K-H, Mima T, Casart Y, Rholl D, Kumar A, Beacham IR, Schweizer HP. 2008. Genetic tools for select agent compliant manipulation of Burkholderia pseudomallei. Appl Environ Microbiol 74:1064-1075. http://dx.doi.org/10.1128/AEM.02430-07.
20. Kovacs-Simon A, Titball RW, Michell SL. 2011. Lipoproteins of bacterial pathogens. Infect Immun 79:548-561. http://dx.doi.org/10.1128/IAI.00682-10.
21. Dev IK, Harvey RJ, Ray PH. 1985. Inhibition of prolipoprotein signal peptidase by globomycin. J Biol Chem 260:5891-5894.
22. Hussain M, Ichihara S, Mizushima S. 1980. Accumulation of glyceridecontaining precursor of the outer membrane lipoprotein in the cytoplasmic membrane of Escherichia coli treated with globomycin. J Biol Chem 255:3707-3712.
23. Ames GF-L, Prody C, Kustu S. 1984. Simple, rapid, and quantitative release of periplasmic proteins by chloroform. J Bacteriol 160:1181-1183.
24. Radolf JD, Chamberlain NR, Clausell A, Norgard MV. 1988. Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent Triton X-114. Infect Immun 56:490-498.
25. Bordier C. 1981. Phase separation of integral membrane proteins in Triton X-114 solution. J Biol Chem 256:1604-1607.
26. Sjostedt A, Tarnvik A, Sandstrom G. 1991. The T-cell-stimulating 17-kilodalton protein of Francisella tularensis LVS is a lipoprotein. Infect Immun 59:3163-3168.
27. Janson H, Heden LO, Forsgren A. 1992. Protein D, the immunoglobulin D-binding protein of Haemophilus influenzae, is a lipoprotein. Infect Immun 60:1336-1342.
28. Tibor A, Decelle B, Letesson JJ. 1999. Outer membrane proteins Omp10, Omp16, and Omp19 of Brucella spp. are lipoproteins. Infect Immun 67:4960-4962.
29. Maeda Y, Makino M, Crick DC, Mahapatra S, Srisungnam S, Takii T, Kashiwabara Y, Brennan PJ. 2002. Novel 33-kilodalton lipoprotein from Mycobacterium leprae. Infect Immun 70:4106-4111. http://dx.doi.org/10.1128/IAI.70.8.4106-4111.2002.
30. Juncker AS, Willenbrock H, Von Heijne G, Brunak S, Nielsen H, Krogh A. 2003. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Protein Sci 12:1652-1662. http://dx.doi.org/10.1110/ps.0303703.
31. Valente FM, Pereira PM, Venceslau SS, Regalla M, Coelho AV, Pereira IA. 2007. The [NiFeSe] hydrogenase from Desulfovibrio vulgaris Hildenborough is a bacterial lipoprotein lacking a typical lipoprotein signal peptide. FEBS Lett 581:3341-3344. http://dx.doi.org/10.1016/j.febslet.2007.06.020.
32. Bootsma HJ, Aerts PC, Posthuma G, Harmsen T, Verhoef J, Van Dijk H, Mooi FR. 1999. Moraxella (Branhamella) catarrhalis BRO β-lactamase: a lipoprotein of Gram-positive origin? J Bacteriol 181:5090-5093.
33. King D, Strynadka N. 2011. Crystal structure of New Delhi metallo-betalactamase reveals molecular basis for antibiotic resistance. Protein Sci 20:1484-1491. http://dx.doi.org/10.1002/pro.697.
34. Gonzalez L, Bahr G, Bonomo RA, Vila A. 2014. Membrane anchoring of carbapenemase Ndm-1 favors protein stability and resistance transfer, abstr C162c. Abstr 54th Intersci Conf Antimicrob Agents Chemother. American Society for Microbiology, Washington, DC.
35. Paetzel M, Karla A, Strynadka NC, Dalbey RE. 2002. Signal peptidases. Chem Rev 102:4549-4580. http://dx.doi.org/10.1021/cr010166y.
36. Tuteja R. 2005. Type I signal peptidase: an overview. Arch Biochem Biophys 441:107-111. http://dx.doi.org/10.1016/j.abb.2005.07.013.
37. Ferrandez Y, Condemine G. 2008. Novel mechanism of outer membrane targeting of proteins in Gram-negative bacteria. Mol Microbiol 69:1349-1357. http://dx.doi.org/10.1111/j.1365-2958.2008.06366.x.
38. Viarre V, Cascales E, Ball G, Michel GP, Filloux A, Voulhoux R. 2009. HxcQ liposecretin is self-piloted to the outer membrane by its N-terminal lipid anchor. J Biol Chem 284:33815-33823. http://dx.doi.org/10.1074/jbc. M109.065938.
39. Winsor GL, Khaira B, Van Rossum T, Lo R, Whiteside MD, Brinkman FSL. 2008. The Burkholderia Genome Database: facilitating flexible queries and comparative analyses. Bioinformatics 24:2803-2804. http://dx.doi.org/10.1093/bioinformatics/btn524.