Inhibition of T-Type Voltage Sensitive Calcium Channel Reduces Load-Induced OA in Mice and Suppresses the Catabolic Effect of Bone Mechanical Stress on Chondrocytes

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Srinivasan, Padma P ^a   Parajuli, Ashutosh ^a   Price, Christopher ^a   Wang, Liyun ^a   Duncan, Randall L ^a   Kirn Safran, Catherine B ^a  

^a UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL T TYPE;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE STRESS; CARTILAGE CELL; CARTILAGE INJURY; CONTROLLED STUDY; GENE EXPRESSION; HYPERTROPHY; IN VITRO STUDY; KNEE; MALE; MECHANICAL STIMULATION; MECHANICAL STRESS; MOUSE; NONHUMAN; OSTEOARTHRITIS; OSTEOBLAST; PROTEIN FUNCTION; SHEAR STRESS; SIGNAL TRANSDUCTION; ANIMAL; BONE; C57BL MOUSE; CHONDROCYTE; METABOLISM; PHYSIOLOGY;

ANIMALS; BONE AND BONES; CALCIUM CHANNELS, T-TYPE; CARTILAGE, ARTICULAR; CHONDROCYTES; MALE; METABOLISM; MICE; MICE, INBRED C57BL; OSTEOBLASTS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 84960145668     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127290     Document Type: Article

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